1. Selection of Ruthenium Polypyridyl Complex-Modified Aptamers for Photodynamic Therapy against Streptococcus Pneumonia
   2025/11/08 by Marie Flamme, Germain Niogret, Luke K. McKenzie +9 · 1 voice · 2 citations
   Biochemistry, Genetics and Molecular Biology · Engineering · Medicine · #Advanced biosensing and bioanalysis techniques #Aptamer #DNA #Nanoplatforms for cancer theranostics #Nucleotide #Photodynamic Therapy Research Studies #Photodynamic therapy #Polymerase #Ruthenium #Systematic evolution of ligands by exponential enrichment
2. Enzyme cascades for the synthesis of nucleotide sugars: Updates to recent production strategies
   2022/11/29 by Hannes Frohnmeyer, Lothar Elling · 11 citations
   Biochemistry, Genetics and Molecular Biology · Chemistry · #Biochemistry #Carbohydrate Chemistry and Synthesis #Chemistry #Enzyme #Enzyme Production and Characterization #Gene #Glycan #Glycoconjugate #Glycoprotein #Glycosylation and Glycoproteins Research #Glycosyltransferase #Nucleotide #Nucleotide sugar #Sugar #Yield (engineering)
3. Nucleotide-amino acid π-stacking interactions initiate photo cross-linking in RNA-protein complexes
   2022/05/17 by Anna Knörlein, Chris P. Sarnowski, Tebbe de Vries +6 · 1 citation
   Biochemistry, Genetics and Molecular Biology · Chemistry · #RNA Research and Splicing #RNA and protein synthesis mechanisms #RNA modifications and cancer #RNA #Stacking #Nucleobase #Nucleotide #Amino acid #RNA splicing #Biochemistry #Protein–protein interaction #Chemistry #Biology #RNA-binding protein #Computational biology #DNA #Gene
4. NADH/NAD+ binding and linked tetrameric assembly of the oncogenic transcription factors CtBP1 and CtBP2
   2022/01/08 by Heidi Erlandsen, Anne M. Jecrois, Jeffry C. Nichols +2 · 8 citations
   Biochemistry, Genetics and Molecular Biology · Chemistry · #Binding site #Biochemistry #Biology #Biophysics #Chemistry #Cofactor #Dimer #Dissociation constant #Enzyme #Gene #Isothermal titration calorimetry #Kruppel-like factors research #Microbial metabolism and enzyme function #NAD+ kinase #Nucleotide #Plasma protein binding #RNA modifications and cancer #Receptor #Stereochemistry #Tetramer
5. Metabolic Reprogramming in Cancer Is Induced to Increase Proton Production
   2020/01/13 by Huiyan Sun, Yi Zhou, Michael Skaro +6 · 25 citations
   Biochemistry, Genetics and Molecular Biology · Chemistry · #ATP Synthase and ATPases Research #Biochemistry #Biology #Cancer #Cancer cell #Cancer research #Cancer, Hypoxia, and Metabolism #Cell #Cell biology #Chemistry #Gene #Genetics #Intracellular #Mitochondrial Function and Pathology #Nucleotide #Reprogramming #Sialic acid #Warburg effect
6. Insights into the Cooperative Nature of ATP Hydrolysis in Actin Filaments
   2018/09/01 by Harshwardhan H. Katkar, Aram Davtyan, Aleksander E. P. Durumeric +5 · 1 citation
   Biochemistry, Genetics and Molecular Biology · Chemistry · Engineering · Materials Science · #ATP hydrolysis #ATPase #Actin #Adhesion, Friction, and Surface Interactions #Binding site #Biochemistry #Biology #Biophysics #Cellular Mechanics and Interactions #Chemical physics #Chemistry #Cooperative binding #Cooperativity #Crystallography #Granularity #Kinetics #Material Dynamics and Properties #Nucleotide #Physics #Protein filament
7. Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome
   2018/04/04 by Yanan Zhu, Wei Li Wang, Daqi Yu +3 · 3 citations
   Biochemistry, Genetics and Molecular Biology · Chemistry · #AAA proteins #ATPase #Biochemistry #Biology #Cell biology #Chemistry #Endoplasmic Reticulum Stress and Disease #Enzyme #Gene #Genetics and Neurodevelopmental Disorders #Mechanism (biology) #Nucleotide #Physics #Proteasome #Ubiquitin and proteasome pathways
8. The Contribution of Nicotinamide Nucleotide Transhydrogenase to Peroxide Detoxification Is Dependent on the Respiratory State and Counterbalanced by Other Sources of NADPH in Liver Mitochondria
   2016/07/30 by Juliana A. Ronchi, Juliana Aparecida Ronchi, Annelise Francisco +6 · 26 citations
   Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #ATP Synthase and ATPases Research #Biochemistry #Chemistry #Coenzyme Q10 studies and effects #Detoxification (alternative medicine) #Enzyme #Gene #Internal medicine #Medicine #Mitochondrial Function and Pathology #Mitochondrion #NAD+ kinase #Nicotinamide #Nucleotide #Organic chemistry #Peroxide #Respiratory chain #Respiratory system
9. Single-nucleotide-resolution mapping of m6A and m6Am throughout the transcriptome
   2015/06/29 by Bastian Linder, Anya V Grozhik, Anya V. Grozhik +7 · 3 citations
   Biochemistry, Genetics and Molecular Biology · Engineering · Medicine · #Biology #Computational biology #Gene #Gene expression #Genetics #HVDC Systems and Fault Protection #Nucleotide #RNA modifications and cancer #Transcriptome #Viral-associated cancers and disorders
10. Activation of Autophagy and Nucleotide-Binding Domain Leucine-Rich Repeat–Containing-Like Receptor Family, Pyrin Domain–Containing 3 Inflammasome during Leishmania infantum–Associated Glomerulonephritis
    2015/06/14 by Kevin J. Esch, Robert G. Schaut, Ian M. Lamb +11 · 26 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Autoimmune and Inflammatory Disorders Research #Biology #Cyclic nucleotide-binding domain #Gene #Genetics #Immunology #Inflammasome #Inflammasome and immune disorders #Leishmania #Leishmania infantum #Leishmaniasis #Microbiology #Nucleotide #Pyrin domain #Receptor #Research on Leishmaniasis Studies #Virology #Visceral leishmaniasis
11. Streptococcus sanguinis Class Ib Ribonucleotide Reductase
    2014/01/01 by Olga V. Makhlynets, Amie K. Boal, DeLacy V. L. Rhodes +3 · 1 citation
    Chemistry · Medicine · #Metal-Catalyzed Oxygenation Mechanisms #Metal complexes synthesis and properties #Infective Endocarditis Diagnosis and Management #Ribonucleotide reductase #Thioredoxin reductase #Cofactor #Biochemistry #Streptococcus sanguinis #Glutaredoxin #Thioredoxin #Flavin adenine dinucleotide #Biology #Ribonucleotide #Reductase #Chemistry #Nucleotide #Enzyme #Streptococcus mutans #Bacteria #Genetics
12. Analysis of CLIP and iCLIP methods for nucleotide-resolution studies of protein-RNA interactions
    2012/08/03 by Yoichiro Sugimoto, Julian König, Shobbir Hussain +4 · 7 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · #RNA Research and Splicing #RNA modifications and cancer #RNA and protein synthesis mechanisms #RNA #Immunoprecipitation #Complementary DNA #Nucleotide #RNA-binding protein #Biology #Computational biology #Molecular biology #Protein–protein interaction #Uridine #Genetics #Chemistry #Gene
13. Analysis of Protein–RNA Interactions with Single‐Nucleotide Resolution Using iCLIP and Next‐Generation Sequencing
    2011/12/14 by Julian König, Nicholas J. McGlincy, Jernej Ule · 1 citation
    Biochemistry, Genetics and Molecular Biology · #RNA and protein synthesis mechanisms #RNA Research and Splicing #RNA modifications and cancer #Computational biology #RNA-binding protein #RNA #Nucleotide #Biology #Gene #Binding site #Genetics
14. Water Molecules in the Nucleotide Binding Cleft of Actin: Effects on Subunit Conformation and Implications for ATP Hydrolysis
    2011/08/14 by Marissa G. Saunders, Gregory A. Voth · 1 citation
    Biochemistry, Genetics and Molecular Biology · Chemistry · #ATP hydrolysis #ATPase #Actin #Active site #Advanced Fluorescence Microscopy Techniques #Biochemistry #Biology #Biophysics #Catalysis #Cellular Mechanics and Interactions #Chemistry #Crystallography #Deprotonation #Enzyme #Microtubule and mitosis dynamics #Nucleotide #Organic chemistry #Protein filament #Protein structure #Protein subunit
15. Mapping in vivo protein-RNA interactions at single-nucleotide resolution from HITS-CLIP data
    2011/06/01 by Chaolin Zhang, Robert B Darnell, Robert B. Darnell · 4 citations
    Biochemistry, Genetics and Molecular Biology · #Argonaute #Biology #Computational biology #Gene #Genetics #Immunoprecipitation #Messenger RNA #Molecular biology #Nucleotide #RNA #RNA Research and Splicing #RNA and protein synthesis mechanisms #RNA interference #RNA modifications and cancer #RNA-binding protein
16. Human mitochondrial mRNAs—like members of all families, similar but different
    2010/03/09 by Richard Temperley, Richard J. Temperley, Mateusz Wydro +3 · 32 citations
    Biochemistry, Genetics and Molecular Biology · #Biology #Coding region #Gene #Genetics #Genomics and Phylogenetic Studies #Intron #Messenger RNA #Mitochondrial DNA #Mitochondrial Function and Pathology #Mitochondrion #Molecular biology #Nucleotide #RNA #RNA and protein synthesis mechanisms #Stop codon #Three prime untranslated region #Transfer RNA #Translation (biology) #Untranslated region
17. Continuous base identification for single-molecule nanopore DNA sequencing
    2009/02/22 by James Clarke, Hai‐Chen Wu, Hai-Chen Wu +5 · 7 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · Engineering · #Adapter (computing) #Advanced biosensing and bioanalysis techniques #Base pair #Base sequence #Biochemistry #Biology #Biophysics #Chemistry #Cleave #Computational biology #Computer science #Cytosine #DNA #DNA polymerase #DNA sequencing #Exonuclease #Gene #Genomic library #Materials science #Nanopore #Nanopore and Nanochannel Transport Studies #Nanopore sequencing #Nanotechnology #Nucleic acid #Nucleotide #RNA modifications and cancer #Sequencing by ligation #Thymine
18. Are histones, tubulin, and actin derived from a common ancestral protein?
    2008/07/09 by John Gardiner, J. Gardiner, P. A. McGee +5 · 1 citation
    Biochemistry, Genetics and Molecular Biology · #Acetylation #Actin #Actin cytoskeleton #Actin-binding protein #Biochemistry #Biology #Cell #Cell biology #Cytoskeleton #DNA #FtsZ #Gene #Genetics #Histone #Histone Deacetylase Inhibitors Research #Microtubule #Nucleotide #Signaling Pathways in Disease #Tubulin #Ubiquitin and proteasome pathways
19. The Electronic Properties of DNA Bases
    2007/09/03 by Mingsheng Xu, Robert G. Endres, Yasuhiko Arakawa · 2 citations
    Engineering · Biochemistry, Genetics and Molecular Biology · Chemistry · #Nanopore and Nanochannel Transport Studies #Advanced biosensing and bioanalysis techniques #DNA and Nucleic Acid Chemistry #DNA #Guanine #Thymine #Density functional theory #Base pair #Scanning tunneling microscope #Nucleobase #Cytosine #Molecule #Quantum tunnelling #A-DNA #DNA sequencing #Chemical physics #Chemistry #Electronic structure #Nanotechnology #Crystallography #Materials science #Computational chemistry #Nucleotide #Optoelectronics #Biochemistry #Gene
20. Deoxyribonucleotides and Disorders of Mitochondrial DNA Integrity
    2004/12/01 by Ann Saada · 2 citations
    Biochemistry, Genetics and Molecular Biology · #Mitochondrial Function and Pathology #Metabolism and Genetic Disorders #ATP Synthase and ATPases Research #Biology #Mitochondrial DNA #Deoxyribonucleotides #Mitochondrion #Deoxyribonucleoside #DNA replication #Genetics #Deoxyribonucleotide #Human genetics #DNA repair #DNA #Nucleotide #Oligonucleotide #Gene
21. Arabidopsis CYP735A1 and CYP735A2 Encode Cytokinin Hydroxylases That Catalyze the Biosynthesis of trans-Zeatin
    2004/07/27 by Kentaro Takei, Tomoyuki Yamaya, Hitoshi Sakakibara · 29 citations
    Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · Chemistry · #Arabidopsis #Auxin #Biochemistry #Biology #Biosynthesis #Chemistry #Cytokinin #Enzyme #Gene #Hydroxylation #Mutant #Nucleoside #Nucleotide #Photosynthetic Processes and Mechanisms #Plant Molecular Biology Research #Plant biochemistry and biosynthesis #Stereochemistry #Zeatin
22. Molecular Basis of an Inherited Form of Incomplete Achromatopsia
    2004/01/07 by Dimitri Tränkner, Herbert Jägle, Susanne Kohl +6 · 2 citations
    Biochemistry, Genetics and Molecular Biology · Neuroscience · #Retinal Development and Disorders #Photoreceptor and optogenetics research #Neuroscience and Neuropharmacology Research #Achromatopsia #Mutant #Genetics #Cyclic nucleotide-gated ion channel #Biology #Phenotype #Mutation #Gene #Protein subunit #Heterologous expression #Biophysics #Cell biology #Nucleotide #Recombinant DNA #Biochemistry #Cyclic nucleotide #Retinal
23. Achromatopsia-associated Mutation in the Human Cone Photoreceptor Cyclic Nucleotide-gated Channel CNGB3 Subunit Alters the Ligand Sensitivity and Pore Properties of Heteromeric Channels
    2003/08/29 by Changhong Peng, Elizabeth D. Rich, Michael D. Varnum · 2 citations
    Biochemistry, Genetics and Molecular Biology · Neuroscience · #Retinal Development and Disorders #Neuroscience and Neuropharmacology Research #Ion channel regulation and function #Cyclic nucleotide-gated ion channel #Achromatopsia #Homomeric #Protein subunit #Mutation #Xenopus #Biology #Transmembrane domain #Cell biology #Biophysics #Genetics #Molecular biology #Biochemistry #Gene #Cyclic nucleotide #Retinal #Nucleotide
24. Comparative analysis of the ATP‐binding sites of Hsp90 by nucleotide affinity cleavage: a distinct nucleotide specificity of the C‐terminal ATP‐binding site
    2003/05/12 by Csaba So ̋ti, Csaba So˝ti, Ákos Vermes +3 · 27 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · #Binding site #Biochemistry #Biology #Chemistry #Cyclic nucleotide-binding domain #Enzyme #GTP' #Heat shock proteins research #Nucleotide
25. Inherited Mitochondrial DNA Depletion
    2003/05/13 by Orly Elpeleg · 2 citations
    Biochemistry, Genetics and Molecular Biology · #ATP Synthase and ATPases Research #Biology #DNA #DNA replication #Gene #Genetics #Metabolism and Genetic Disorders #Mitochondrial DNA #Mitochondrial Function and Pathology #Mitochondrion #Nucleotide #Phenotype
26. Exchange of the Actin-bound Nucleotide in Intact Arterial Smooth Muscle
    2001/12/01 by Michael Bárány, John T. Barron, Liping Gu +1 · 1 citation
    Biochemistry, Genetics and Molecular Biology · Medicine · Chemistry · #Cellular Mechanics and Interactions #Cardiomyopathy and Myosin Studies #Cell Adhesion Molecules Research #Actin #Nucleotide #Chemistry #Cardiology #Anatomy #Biology #Biochemistry #Medicine #Gene
27. Force and kinetic barriers to unzipping of the DNA double helix
    2001/07/10 by Simona Cocco, S. Cocco, R. Monasson +3 · 1 citation
    Biochemistry, Genetics and Molecular Biology · Chemistry · Engineering · Physics and Astronomy · #Biochemistry #Biology #Biophysics #Chemistry #Classical mechanics #Composite material #DNA #Double stranded #Force Microscopy Techniques and Applications #Helix (gastropod) #Kinetic energy #Kinetics #Materials science #Molecule #Nanofabrication and Lithography Techniques #Near-Field Optical Microscopy #Nucleotide #Physics #Rigidity (electromagnetism) #cond-mat.stat-mech #q-bio
28. Development and current status of the CHARMM force field for nucleic acids
    2000/01/01 by Alexander D. MacKerell, Nilesh Banavali, Nilesh K. Banavali +1 · 34 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · Materials Science · #Biochemistry #Chemistry #Computational chemistry #DNA #DNA and Nucleic Acid Chemistry #Enzyme Structure and Function #Field (mathematics) #Force field (fiction) #Materials science #Molecular dynamics #Nanotechnology #Nucleic acid #Nucleotide #Physics #Protein Structure and Dynamics #RNA
29. Crystal Structures of Substrates and Products Bound to the Phosphoglycerate Kinase Active Site Reveal the Catalytic Mechanism
    1998/03/01 by B Bernstein, Bradley E. Bernstein, Wim G. J. Hol · 23 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Active site #Biochemical and Molecular Research #Biochemistry #Carbohydrate Chemistry and Synthesis #Catalysis #Chemistry #Crystallography #Enzyme #Glycogen Storage Diseases and Myoclonus #Nucleotide #Phosphoglycerate kinase #Stereochemistry #Ternary complex
30. Autotaxin Is an Exoenzyme Possessing 5′-Nucleotide Phosphodiesterase/ATP Pyrophosphatase and ATPase Activities
    1997/01/01 by Timothy Clair, Hoi Young Lee, Lance A. Liotta +1 · 3 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · #ATPase #Adenosine and Purinergic Signaling #Adenylate kinase #Autotaxin #Biochemistry #Biology #Calcium signaling and nucleotide metabolism #Cell biology #Chemistry #Enzyme #Enzyme function and inhibition #Exoenzyme #Lysophosphatidic acid #Nucleotide #Phosphodiesterase #Pyrophosphatase #Receptor

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