Robert B. Darnell

1. HITS-CLIP yields genome-wide insights into brain alternative RNA processing
   2008/11/01 by Donny D. Licatalosi, Aldo Mele, John J. Fak +11 · 14 citations
   Biochemistry, Genetics and Molecular Biology · #Alternative splicing #Biology #Computational biology #Gene #Genetics #Genome #Messenger RNA #Polyadenylation #RNA #RNA Research and Splicing #RNA and protein synthesis mechanisms #RNA modifications and cancer #RNA splicing #RNA-binding protein #Untranslated region
2. CLIP Identifies Nova-Regulated RNA Networks in the Brain
   2003/11/13 by Jernej Ule, Kirk B. Jensen, Matteo Ruggiu +3 · 9 citations
   Biochemistry, Genetics and Molecular Biology · #RNA Research and Splicing #Genetics and Neurodevelopmental Disorders #RNA and protein synthesis mechanisms #RNA splicing #RNA #Biology #RNA-binding protein #Gephyrin #Alternative splicing #Cell biology #Messenger RNA #Gene #Molecular biology #Genetics #Glycine receptor #Glycine #Amino acid
3. Argonaute HITS-CLIP decodes microRNA–mRNA interaction maps
   2009/06/17 by Sung Wook, Sung Wook Chi, Julie B. Zang +2 · 8 citations
   Biochemistry, Genetics and Molecular Biology · #Argonaute #Biology #Cell biology #Computational biology #Drosha #Gene #Gene silencing #Genetics #Messenger RNA #MicroRNA in disease regulation #RNA #RNA Research and Splicing #RNA interference #RNA regulation and disease #RNA silencing #microRNA
4. FMRP Stalls Ribosomal Translocation on mRNAs Linked to Synaptic Function and Autism
   2011/07/01 by Jennifer C. Darnell, Jennifer C. Darnell, Sarah J. Van Driesche +19 · 6 citations
   Biochemistry, Genetics and Molecular Biology · Neuroscience · #Autism #Biology #Cell biology #Chromosomal translocation #Function (biology) #Gene #Genetics #Genetics and Neurodevelopmental Disorders #Neuroscience #RNA Research and Splicing #RNA and protein synthesis mechanisms #Ribosomal RNA
5. Mapping in vivo protein-RNA interactions at single-nucleotide resolution from HITS-CLIP data
   2011/06/01 by Chaolin Zhang, Robert B. Darnell, Robert B Darnell · 4 citations
   Biochemistry, Genetics and Molecular Biology · #Argonaute #Biology #Computational biology #Gene #Genetics #Immunoprecipitation #Messenger RNA #Molecular biology #Nucleotide #RNA #RNA Research and Splicing #RNA and protein synthesis mechanisms #RNA interference #RNA modifications and cancer #RNA-binding protein
6. Mapping Argonaute and conventional RNA-binding protein interactions with RNA at single-nucleotide resolution using HITS-CLIP and CIMS analysis
   2014/01/09 by Michael J. Moore, Michael J Moore, Chaolin Zhang +7 · 3 citations
   Biochemistry, Genetics and Molecular Biology · #Argonaute #Biology #Computational biology #Gene #Genetics #Immunoprecipitation #RNA #RNA Research and Splicing #RNA and protein synthesis mechanisms #RNA interference #RNA modifications and cancer #RNA-binding protein #microRNA
7. HITS‐CLIP: panoramic views of protein–RNA regulation in living cells
   2010/08/02 by Robert B. Darnell · 4 citations
   Biochemistry, Genetics and Molecular Biology · #RNA Research and Splicing #RNA and protein synthesis mechanisms #RNA regulation and disease #RNA #Computational biology #Context (archaeology) #Transcription (linguistics) #Biology #DNA #Gene #Genetics
8. Muscleblind-like 2-Mediated Alternative Splicing in the Developing Brain and Dysregulation in Myotonic Dystrophy
   2012/08/01 by Konstantinos Charizanis, Kuang-Yung Lee, Ranjan Batra +29 · 3 citations
   Biochemistry, Genetics and Molecular Biology · Neuroscience · Psychology · #Alternative splicing #Biology #Exon #Gene #Genetic Neurodegenerative Diseases #Genetics #Mitochondrial Function and Pathology #Muscle Physiology and Disorders #Myotonic dystrophy #Neuroscience #Psychology #RNA #RNA splicing
9. Neuronal Elav-like (Hu) Proteins Regulate RNA Splicing and Abundance to Control Glutamate Levels and Neuronal Excitability
   2012/09/01 by Gulayse Ince-Dunn, Hirotaka James Okano, Hirotaka J. Okano +20 · 3 citations
   Biochemistry, Genetics and Molecular Biology · Chemistry · Neuroscience · #Alternative splicing #Biochemistry #Biology #Cell biology #Chemistry #Gene #Glutamate receptor #Messenger RNA #Neuroscience #Premovement neuronal activity #RNA #RNA Research and Splicing #RNA and protein synthesis mechanisms #RNA modifications and cancer #RNA splicing
10. Ptbp2 represses adult-specific splicing to regulate the generation of neuronal precursors in the embryonic brain
    2012/07/15 by Donny D. Licatalosi, Masato Yano, John J. Fak +4 · 3 citations
    Biochemistry, Genetics and Molecular Biology · Neuroscience · #RNA Research and Splicing #RNA modifications and cancer #Cancer-related molecular mechanisms research #Biology #Neurogenesis #Alternative splicing #Exon #RNA-binding protein #Cell biology #RNA splicing #Neocortex #Embryonic stem cell #Neural stem cell #Long non-coding RNA #Progenitor cell #Polypyrimidine tract-binding protein #RNA #Genetics #Stem cell #Gene #Neuroscience
11. A majority of m6A residues are in the last exons, allowing the potential for 3′ UTR regulation
    2015/09/24 by Shengdong Ke, Endalkachew A. Alemu, Claudia Mertens +12 · 2 citations
    Biochemistry, Genetics and Molecular Biology · #RNA modifications and cancer #Cancer-related gene regulation #RNA Research and Splicing #Exon #Biology #Untranslated region #Exon trapping #Genetics #Messenger RNA #Exon shuffling #Intron #Stop codon #Molecular biology #Gene #Tandem exon duplication #Alternative splicing
12. A humanized NOVA1 splicing factor alters mouse vocal communications
    2025/02/18 by Yoko Tajima, César D. M. Vargas, Keiichi Ito +9 · 1 voice · 2 citations
    Biochemistry, Genetics and Molecular Biology · #Cancer-related molecular mechanisms research #RNA Research and Splicing #RNA and protein synthesis mechanisms
13. m6A mRNA modifications are deposited in nascent pre-mRNA and are not required for splicing but do specify cytoplasmic turnover
    2017/05/15 by Shengdong Ke, Amy Pandya‐Jones, Yuhki Saito +7 · 1 citation
    Biochemistry, Genetics and Molecular Biology · #RNA modifications and cancer #Cancer-related gene regulation #Cancer-related molecular mechanisms research #Biology #RNA splicing #Messenger RNA #Precursor mRNA #Exon #Molecular biology #Intron #RNA #Mature messenger RNA #P-bodies #Nucleoplasm #Cell biology #Small nuclear RNA #Cytoplasm #Genetics #Non-coding RNA #Gene #Translation (biology) #Nucleolus
14. CLIP: A method for identifying protein–RNA interaction sites in living cells
    2005/12/01 by Jernej Ule, Kirk Jensen, Aldo Mele +1 · 1 citation
15. CLIP (Cross-Linking and Immunoprecipitation) Identification of RNAs Bound by a Specific Protein
    2012/11/01 by Robert B. Darnell · 1 citation
    Biochemistry, Genetics and Molecular Biology · Chemistry · #RNA and protein synthesis mechanisms #RNA modifications and cancer #RNA Research and Splicing #RNA #Immunoprecipitation #Ribosome #Computational biology #RNA-binding protein #Biology #Chemistry #Cell biology #Biochemistry #Gene