- Homer condensates orchestrate YAP–Wnt signaling crosstalk downstream of the Crumbs polarity complex
2026/07/15 by Siti Maryam J. M. Yatim, Linda Jiabao Woo, Yuhong Chen +2 · 1 voice
Biochemistry, Genetics and Molecular Biology · #Cancer-related gene regulation #Hippo pathway signaling and YAP/TAZ #Wnt/β-catenin signaling in development and cancer
- DNMT1 loss leads to hypermethylation of a subset of late replicating domains by DNMT3A
2026/04/02 by Ioannis Kafetzopoulos, Francesca Taglini, Moira Pasquier +5 · 1 voice · 1 citation
Biochemistry, Genetics and Molecular Biology · #Epigenetics and DNA Methylation #Cancer-related gene regulation #Cancer Genomics and Diagnostics
- Genotoxic stress triggers Scd6-dependent regulation of translation to modulate the DNA damage response
2025/04/24 by Gayatri Mohanan, Raju Roy, Hélène Malka-Mahieu +8 · 1 voice · 1 citation
Biochemistry, Genetics and Molecular Biology · #Cancer-related gene regulation #RNA Research and Splicing #RNA modifications and cancer
- The landscape of N6-methyladenosine in localized primary prostate cancer
2025/03/24 by Xin Xu, Helen Zhu, Helen He Zhu +51 · 1 voice · 2 citations
Biochemistry, Genetics and Molecular Biology · #RNA modifications and cancer #Cancer-related gene regulation #Cancer-related molecular mechanisms research
- Aberrant miRNA expression and protein arginine methyltransferase 5 (PRMT5) in cancer: A review
2025/02/22 by Saïd Sif, Saı̈d Sif, Majdi Al Alawneh · 1 citation
Biochemistry, Genetics and Molecular Biology · #Cancer-related gene regulation
- DNMT1 loss leads to hypermethylation of a subset of late replicating domains by DNMT3A
2024/12/19 by Ioannis Kafetzopoulos, Francesca Taglini, Hazel Davidson‐Smith +1 · 2 voices · 1 citation
Biochemistry, Genetics and Molecular Biology · #Cancer-related gene regulation #Epigenetics and DNA Methylation #RNA modifications and cancer
- Epigenetics-targeted drugs: current paradigms and future challenges
2024/11/26 by Wanlin Dai, Xinbo Qiao, Yuanyuan Fang +9 · 1 voice · 2 citations
Biochemistry, Genetics and Molecular Biology · #Cancer-related gene regulation #Epigenetics and DNA Methylation #RNA modifications and cancer
- Methylarginine targeting chimeras for lysosomal degradation of intracellular proteins
2024/10/16 by Laurence J. Seabrook, Carolina N. Franco, Cody A. Loy +14 · 1 voice · 1 citation
Biochemistry, Genetics and Molecular Biology · #Protein Degradation and Inhibitors #Ubiquitin and proteasome pathways #Cancer-related gene regulation
- Reading m<sup>6</sup>A marks in mRNA: A potent mechanism of gene regulation in plants
2024/10/04 by Thi Kim Hang Nguyen, Hunseung Kang · 1 voice · 2 citations
Biochemistry, Genetics and Molecular Biology · Engineering · #RNA modifications and cancer #Cancer-related gene regulation #HVDC Systems and Fault Protection
- Chemoproteomic mapping of the N-terminal cysteinome
2024/09/24 by Esben B. Svenningsen, Fatih Demir, Florian Kromm +4 · 2 voices
Biochemistry, Genetics and Molecular Biology · Medicine · #Cancer-related gene regulation #Peptidase Inhibition and Analysis #Ubiquitin and proteasome pathways
- First-in-human study of AMG 193, an MTA-cooperative PRMT5 inhibitor, in patients with MTAP-deleted solid tumors: results from phase I dose exploration
2024/09/16 by Jordi Rodón, J. Rodon, H. Prenen +33 · 1 voice · 3 citations
Biochemistry, Genetics and Molecular Biology · #Cancer-related gene regulation #Polyamine Metabolism and Applications #Virus-based gene therapy research
- De Novo Genes
2024/08/01 by Li Zhao, Nicolas Svetec, David J. Begun +1 · 1 voice · 14 citations
Biochemistry, Genetics and Molecular Biology · #Cancer-related gene regulation #Epigenetics and DNA Methylation #RNA modifications and cancer
- Not All Layers of LLMs Are Necessary During Inference
2024/03/04 by Siqi Fan, Fan, Siqi, Xin Jiang +15 · 12 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Artificial Intelligence (cs.AI) #Cancer-related gene regulation #Cancer-related molecular mechanisms research #Cell Adhesion Molecules Research #Computation and Language (cs.CL) #FOS: Computer and information sciences #Machine Learning (cs.LG)
- Generative Flows on Discrete State-Spaces: Enabling Multimodal Flows with Applications to Protein Co-Design
2024/02/07 by Andrew T. Campbell, Campbell, Andrew, Jason Yim +7 · 50 citations
Biochemistry, Genetics and Molecular Biology · Computer Science · #Biomedical Text Mining and Ontologies #Cancer-related gene regulation #FOS: Biological sciences #FOS: Computer and information sciences #Machine Learning (cs.LG) #Machine Learning (stat.ML) #Quantitative Methods (q-bio.QM) #Topic Modeling
- Budding yeast as an ideal model for elucidating the role of <i>N</i><sup>6</sup>‐methyladenosine in regulating gene expression
2024/01/18 by Waleed S. Albihlal, Wei Yee Chan, Folkert J. van Werven · 1 citation
Biochemistry, Genetics and Molecular Biology · Engineering · #RNA modifications and cancer #HVDC Systems and Fault Protection #Cancer-related gene regulation
- Why Should This Article Be Deleted? Transparent Stance Detection in Multilingual Wikipedia Editor Discussions
2023/10/09 by Lucie-Aimée Kaffee, Kaffee, Lucie-Aimée, Arnav Arora +3 · 1 citation
Biochemistry, Genetics and Molecular Biology · Computer Science · Social Sciences · #Cancer-related gene regulation #Computation and Language (cs.CL) #Computers and Society (cs.CY) #FOS: Computer and information sciences #Hate Speech and Cyberbullying Detection #Machine Learning (cs.LG) #Wikis in Education and Collaboration
- PI3K/Akt signaling in urological cancers: Tumorigenesis function, therapeutic potential, and therapy response regulation
2023/07/23 by Sahar Rezaei, Negin Nikpanjeh, Aryan Rezaee +15 · 13 citations
Biochemistry, Genetics and Molecular Biology · #Cancer-related gene regulation #Protein Degradation and Inhibitors #Ubiquitin and proteasome pathways
- FBXO22 Mediates the NGF/TRKA Signaling Pathway in Bone Metastases in Prostate Cancer
2023/06/08 by Yuehua Zhang, Wen Li, Shenghu Guo +8 · 9 citations
Biochemistry, Genetics and Molecular Biology · #Kruppel-like factors research #Cancer-related gene regulation #Wnt/β-catenin signaling in development and cancer
- A DNA methylation atlas of normal human cell types
2023/01/04 by Netanel Loyfer, Judith Magenheim, Ayelet Peretz +50 · 19 citations
Biochemistry, Genetics and Molecular Biology · #Epigenetics and DNA Methylation #Cancer-related gene regulation #RNA modifications and cancer
- Cancer epigenetics in clinical practice
2022/12/13 by Veronica Davalos, Verónica Dávalos, Manel Esteller · 30 citations
Biochemistry, Genetics and Molecular Biology · #Epigenetics and DNA Methylation #Histone Deacetylase Inhibitors Research #Cancer-related gene regulation
- Structure-based Drug Design with Equivariant Diffusion Models
2022/10/24 by Arne Schneuing, Schneuing, Arne, Charles B. Harris +22 · 40 citations
Computer Science · Medicine · Biochemistry, Genetics and Molecular Biology · #Computational Drug Discovery Methods #Monoclonal and Polyclonal Antibodies Research #Cancer-related gene regulation
- WNT signaling and cancer stemness
2022/07/15 by Masuko Katoh, Masaru Katoh · 2 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Wnt/β-catenin signaling in development and cancer #Cancer Cells and Metastasis #Cancer-related gene regulation
- Diffusion probabilistic modeling of protein backbones in 3D for the motif-scaffolding problem
2022/06/08 by Brian L. Trippe, Trippe, Brian L., Jason Yim +11 · 25 citations
Biochemistry, Genetics and Molecular Biology · Computer Science · #Biomolecules (q-bio.BM) #Cancer-related gene regulation #FOS: Biological sciences #FOS: Computer and information sciences #Machine Learning (cs.LG) #Machine Learning (stat.ML) #Protein Structure and Dynamics #Software Engineering Research
- Wnt/β-catenin signalling: function, biological mechanisms, and therapeutic opportunities
2022/01/03 by Jiaqi Liu, Qing Xiao, Jiani Xiao +6 · 18 citations
Biochemistry, Genetics and Molecular Biology · #Cancer-related gene regulation #Epigenetics and DNA Methylation #Wnt/β-catenin signaling in development and cancer
- Glycogen synthesis and beyond, a comprehensive review of GSK3 as a key regulator of metabolic pathways and a therapeutic target for treating metabolic diseases
2021/11/03 by Li Wang, Jiajia Li, Li‐jun Di · 4 citations
Biochemistry, Genetics and Molecular Biology · #Wnt/β-catenin signaling in development and cancer #Cancer-related gene regulation #Metabolism, Diabetes, and Cancer
- Variants in the degron of AFF3 are associated with intellectual disability, mesomelic dysplasia, horseshoe kidney, and epileptic encephalopathy
2021/05/01 by Norine Voisin, Rhonda E. Schnur, Sofia Douzgou +74 · 16 citations
Biochemistry, Genetics and Molecular Biology · #Ubiquitin and proteasome pathways #Genetics and Neurodevelopmental Disorders #Cancer-related gene regulation
- Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia
2021/04/26 by Eliza Yankova, Wesley Blackaby, Mark Albertella +26 · 15 citations
Biochemistry, Genetics and Molecular Biology · #Cancer-related gene regulation #RNA Research and Splicing #RNA modifications and cancer
- Yes associated protein 1 promotes resistance to 5-fluorouracil in gastric cancer by regulating GLUT3-dependent glycometabolism reprogramming of tumor-associated macrophages
2021/03/13 by Zhanke He, Da Chen, Jiani Wu +9 · 25 citations
Biochemistry, Genetics and Molecular Biology · #Hippo pathway signaling and YAP/TAZ #Cancer-related gene regulation #Ubiquitin and proteasome pathways
- The role of m6A modification in the biological functions and diseases
2021/02/21 by Xiulin Jiang, Baiyang Liu, Zhi Nie +5 · 7 citations
Biochemistry, Genetics and Molecular Biology · #RNA modifications and cancer #Cancer-related gene regulation #Cancer-related molecular mechanisms research
- Targeting the Wnt/β-catenin signaling pathway in cancer
2020/12/01 by Ya Zhang, Xin Wang · 4 citations
Biochemistry, Genetics and Molecular Biology · #Wnt/β-catenin signaling in development and cancer #Cancer-related gene regulation #Hedgehog Signaling Pathway Studies
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