1. Nuclear speckles enable processing of RNA from GC-rich isochores
   2026/02/25 by Michał Małszycki, Lisa Martina, İbrahim Avşar Ilık +12 · 3 voices · 3 citations
   Biochemistry, Genetics and Molecular Biology · Physics and Astronomy · #Downregulation and upregulation #Gene #Intron #Nuclear Structure and Function #Organelle #Origins and Evolution of Life #RNA #RNA Research and Splicing #RNA splicing #Rna processing #Speckle pattern #Trans-splicing
2. TDP-43 dysfunction leads to the accumulation of cryptic transposable element-derived exons, crypTEs, in iPSC derived neurons and ALS/FTD patient tissues
   2026/01/09 by Isobel Bolger, Regina Shaw, Oliver H. Tam +7 · 2 voices
   Biochemistry, Genetics and Molecular Biology · Medicine · Neuroscience · #Alternative splicing #Amyotrophic Lateral Sclerosis Research #Exon #Gene #Gene expression #Genetic Neurodegenerative Diseases #Intron #RNA #RNA Research and Splicing #RNA splicing #Regulation of gene expression #Transposable element
3. Hemoglobin-Gene Cluster Deletions in Antarctic White-Blooded Icefishes Facilitated by Transposable Elements
   2025/09/25 by Thomas Desvignes, Angel G. Rivera‐Colón, John H. Postlethwait · 1 voice · 2 citations
   Biochemistry, Genetics and Molecular Biology · Environmental Science · #Fish biology, ecology, and behavior #Gene #Gene cluster #Gene duplication #Hemoglobin #Hemoglobin structure and function #Intron #Phylogenetics #Physiological and biochemical adaptations #Transposable element #myr
4. Structural basis for the evolution of a domesticated group II intron–like reverse transcriptase to function in host cell DNA repair
   2025/07/29 by Seung Kuk Park, Mo Guo, Jennifer L. Stamos +4 · 1 voice · 2 citations
   Biochemistry, Genetics and Molecular Biology · #Bacterial Genetics and Biotechnology #Biology #CRISPR and Genetic Engineering #Computational biology #DNA #DNA repair #Gene #Genetics #Group II intron #Homologous recombination #Intron #RNA #RNA and protein synthesis mechanisms #RNA splicing #Reverse transcriptase
5. The genetic basis of tail-loss evolution in humans and apes
   2021/09/16 by Bo Xia, Weimin Zhang, Aleksandra Wudzinska +9 · 1 citation
   Biochemistry, Genetics and Molecular Biology · #RNA Research and Splicing #Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities #Cancer-related molecular mechanisms research #Alu element #Biology #Exon #Genetics #Phenotype #Lineage (genetic) #Evolutionary biology #Genome #Brachyury #Intron #Gene #Most recent common ancestor #Gene duplication #Human genome
6. m6A mRNA modifications are deposited in nascent pre-mRNA and are not required for splicing but do specify cytoplasmic turnover
   2017/05/15 by Shengdong Ke, Amy Pandya‐Jones, Yuhki Saito +7 · 1 citation
   Biochemistry, Genetics and Molecular Biology · #RNA modifications and cancer #Cancer-related gene regulation #Cancer-related molecular mechanisms research #Biology #RNA splicing #Messenger RNA #Precursor mRNA #Exon #Molecular biology #Intron #RNA #Mature messenger RNA #P-bodies #Nucleoplasm #Cell biology #Small nuclear RNA #Cytoplasm #Genetics #Non-coding RNA #Gene #Translation (biology) #Nucleolus
7. A majority of m6A residues are in the last exons, allowing the potential for 3′ UTR regulation
   2015/09/24 by Shengdong Ke, Endalkachew A. Alemu, Claudia Mertens +12 · 2 citations
   Biochemistry, Genetics and Molecular Biology · #RNA modifications and cancer #Cancer-related gene regulation #RNA Research and Splicing #Exon #Biology #Untranslated region #Exon trapping #Genetics #Messenger RNA #Exon shuffling #Intron #Stop codon #Molecular biology #Gene #Tandem exon duplication #Alternative splicing
8. Complete plastid genomes from Ophioglossum californicum, Psilotum nudum, and Equisetum hyemale reveal an ancestral land plant genome structure and resolve the position of Equisetales among monilophytes
   2013/01/11 by Felix Grewe, Wenhu Guo, Emily A Gubbels +2 · 2 citations
   Biochemistry, Genetics and Molecular Biology · Agricultural and Biological Sciences · #Genomics and Phylogenetic Studies #Protist diversity and phylogeny #Fern and Epiphyte Biology #Biology #Fern #Phylogenetic tree #Genome #Plastid #Lineage (genetic) #Sister group #Phylogenomics #Plant evolution #Evolutionary biology #Phylogenetics #Intron #Botany #Genetics #Gene #Chloroplast #Clade
9. Extremely high major histocompatibility complex class IIb gene intron 2 variation and population structure in Chinese alligator
   2012/08/15 by CHUANPENG NIE, Chuanpeng Nie, YANYAN LI +5 · 1 citation
   Agricultural and Biological Sciences · Immunology and Microbiology · #Alligator #American alligator #Animal Virus Infections Studies #Aquaculture disease management and microbiota #Biology #Ecology #Evolutionary biology #Gene #Genetics #Intron #Major histocompatibility complex #Population #interferon and immune responses
10. Evolutionary origin of β-defensins
    2012/02/25 by Shunyi Zhu, Bin Gao · 1 citation
    Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · #Antimicrobial Peptides and Activities #Beta defensin #Biology #Conserved sequence #Defensin #Evolutionary biology #Exon #Exon shuffling #Gene #Genetics #Intron #Invertebrate Immune Response Mechanisms #Lineage (genetic) #Peptide sequence #Phylogenetic tree #Phylogenetics #Phylum #Protein Hydrolysis and Bioactive Peptides #Tandem exon duplication #Vertebrate
11. Using positional distribution to identify splicing elements and predict pre-mRNA processing defects in human genes
    2011/06/17 by Kian‐Huat Lim, Luciana Ferraris, Madeleine E. Filloux +2 · 1 citation
    Biochemistry, Genetics and Molecular Biology · #Alternative splicing #Biology #Exon #Exonic splicing enhancer #Gene #Genetics #Intron #Minigene #RNA #RNA Research and Splicing #RNA and protein synthesis mechanisms #RNA modifications and cancer #RNA splicing #Ribonucleoprotein #SR protein #Splicing factor
12. iCLIP reveals the function of hnRNP particles in splicing at individual nucleotide resolution
    2010/07/01 by Julian König, Kathi Zarnack, Gregor Rot +8 · 18 citations
    Biochemistry, Genetics and Molecular Biology · #Alternative splicing #Biology #Cell biology #Exon #Exonic splicing enhancer #Gene #Genetics #Heterogeneous nuclear ribonucleoprotein #Heterogeneous ribonucleoprotein particle #Immunoprecipitation #Intron #Precursor mRNA #RNA #RNA Research and Splicing #RNA and protein synthesis mechanisms #RNA modifications and cancer #RNA splicing #RNA-binding protein #Ribonucleoprotein #Small nuclear ribonucleoprotein
13. Human mitochondrial mRNAs—like members of all families, similar but different
    2010/03/09 by Richard J. Temperley, Richard Temperley, Mateusz Wydro +3 · 32 citations
    Biochemistry, Genetics and Molecular Biology · #Biology #Coding region #Gene #Genetics #Genomics and Phylogenetic Studies #Intron #Messenger RNA #Mitochondrial DNA #Mitochondrial Function and Pathology #Mitochondrion #Molecular biology #Nucleotide #RNA #RNA and protein synthesis mechanisms #Stop codon #Three prime untranslated region #Transfer RNA #Translation (biology) #Untranslated region
14. Splicing factor SFRS1 recognizes a functionally diverse landscape of RNA transcripts
    2008/12/30 by Jeremy R. Sanford, Xin Wang, Matthew Mort +5 · 7 citations
    Biochemistry, Genetics and Molecular Biology · #RNA and protein synthesis mechanisms #RNA Research and Splicing #RNA modifications and cancer #Biology #RNA splicing #Genetics #Alternative splicing #Exon #Intron #Gene #Splicing factor #RNA-binding protein #Minigene #Exonic splicing enhancer #Computational biology #RNA
15. Phylogenetic relationships within Passerida (Aves: Passeriformes): A review and a new molecular phylogeny based on three nuclear intron markers
    2008/06/01 by Ulf S. Johansson, Jon Fjeldså, Rauri C.K. Bowie +1 · 7 citations
    Biochemistry, Genetics and Molecular Biology · Earth and Planetary Sciences · #Biology #Clade #Evolution and Paleontology Studies #Evolutionary biology #Gene #Genetic diversity and population structure #Genetics #Genomics and Phylogenetic Studies #Intron #Mitochondrial DNA #Molecular phylogenetics #Monophyly #Nuclear gene #Phylogenetic tree #Phylogenetics #Zoology
16. A Three–Single-Nucleotide Polymorphism Haplotype in Intron 1 of OCA2 Explains Most Human Eye-Color Variation
    2007/01/19 by David L. Duffy, Grant W. Montgomery, Wei Chen +7 · 2 citations
    Biochemistry, Genetics and Molecular Biology · Nursing · #Biochemical Analysis and Sensing Techniques #Biology #Evolutionary biology #Gene #Genetic variation #Genetics #Genotype #Haplotype #Intron #Polymorphism (computer science) #Retinal Development and Disorders #Single-nucleotide polymorphism #Variation (astronomy) #melanin and skin pigmentation
17. Structural Basis for Recognition and Sequestration of UUUOH 3′ Temini of Nascent RNA Polymerase III Transcripts by La, a Rheumatic Disease Autoantigen
    2006/01/01 by Marianna Teplova, Yu-Ren Yuan, Anh Tuân Phan +5 · 1 citation
    Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · #Biology #Cell biology #DNA #Exonuclease #Galectins and Cancer Biology #Gene #Gene expression #Genetics #Intron #Molecular biology #Polymerase #RNA #RNA Research and Splicing #RNA and protein synthesis mechanisms #RNA polymerase II #RNA polymerase III #RNA splicing #RNA-binding protein #RNA-dependent RNA polymerase
18. Molecular Studies of Subfamily Gilliesioideae (Alliaceae)
    2006/01/01 by Michael F. Fay, Paula J. Rudall, Mark W. Chase · 2 citations
    Biochemistry, Genetics and Molecular Biology · Agricultural and Biological Sciences · #Plant and Fungal Species Descriptions #Plant Diversity and Evolution #Plant and animal studies #Biology #Polyphyly #Subfamily #Evolutionary biology #Taxon #Intron #Ribosomal DNA #Intergenic region #Botany #Genetics #Genome #Phylogenetics #Clade #Gene
19. Recurrent inversion breaking intron 1 of the factor VIII gene is a frequent cause of severe hemophilia A
    2002/01/01 by Richard D. Bagnall, Naushin Waseem, Peter M. Green +2 · 27 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Biology #Cancer-related gene regulation #Chromosomal inversion #Chromosome #Chronic Myeloid Leukemia Treatments #Cosmid #Exon #Gene #Genetics #Hemophilia Treatment and Research #Intron #Molecular biology
20. Fine organization of Bombyx mori fibroin heavy chain gene
    2000/06/15 by Cong‐Zhao Zhou · 3 citations
    Biochemistry, Genetics and Molecular Biology · Materials Science · #Animal Genetics and Reproduction #Biology #Bombyx #Bombyx mori #Coding region #Conserved sequence #Exon #Fibroin #Gene #Genetics #Genome #Genomic organization #Homology (biology) #Insect and Arachnid Ecology and Behavior #Intron #Peptide sequence #Repeated sequence #SILK #Sequence (biology) #Silk-based biomaterials and applications #Tandem repeat
21. Molecular Cloning of the Mouse Apolipoprotein D Gene and Its Upregulated Expression in Niemann-Pick Disease Type C Mouse Model
    1996/10/01 by Kunihiro Yoshida, Emily S. Cleaveland, James W. Nagle +6 · 3 citations
    Medicine · Biochemistry, Genetics and Molecular Biology · #Lysosomal Storage Disorders Research #Pregnancy and preeclampsia studies #Retinoids in leukemia and cellular processes #Biology #Molecular biology #Exon #Northern blot #Lipocalin #Gene #Apolipoprotein B #In situ hybridization #Gene expression #Prohibitin #Intron #Genetics #Endocrinology
22. One gene, two transcripts: isolation of an alternative transcript encoding for the autoantigen La/SS-B from a cDNA library of a patient with primary Sjögrens' syndrome.
    1994/12/01 by Helmut Tröster, Thomas Metzger, Imre Semsei +4 · 3 citations
    Medicine · Immunology and Microbiology · #Monoclonal and Polyclonal Antibodies Research #Galectins and Cancer Biology #Systemic Lupus Erythematosus Research #Exon #Intron #Biology #Molecular biology #Complementary DNA #cDNA library #Alternative splicing #Gene #RNA splicing #Genetics #Transcription (linguistics) #Genomic library #Messenger RNA #RNA #Peptide sequence
23. Structure, chromosome location, and expression of the human smooth muscle (enteric type) gamma-actin gene: evolution of six human actin genes.
    1991/06/01 by T. Miwa, Yoshitaka Manabe, Kiyoshi Kurokawa +5 · 1 citation
    Biochemistry, Genetics and Molecular Biology · #RNA and protein synthesis mechanisms #Fungal and yeast genetics research #RNA Research and Splicing #Biology #Intron #Gene #Genetics #Exon #Untranslated region #Actin #Molecular biology #Coding region #RNA
24. An internal deletion within an 11p13 zinc finger gene contributes to the development of Wilms' tumor
    1990/06/01 by Daniel A. Haber, Alan J. Buckler, Alan Buckler +7 · 1 citation
    Biochemistry, Genetics and Molecular Biology · Medicine · #Allele #Biology #Carcinogenesis #Ethics and Legal Issues in Pediatric Healthcare #Exon #Gene #Genetics #Intron #Loss of heterozygosity #Molecular biology #Prenatal Screening and Diagnostics #Renal and related cancers #Transcription factor #Tumor suppressor gene #Wilms' tumor #Zinc finger
25. Genomic structure and amino acid sequence domains of the human La autoantigen.
    1988/12/01 by J C Chambers, Daniel J. Kenan, Benjamín Martín +1 · 8 citations
    Medicine · Biochemistry, Genetics and Molecular Biology · #Monoclonal and Polyclonal Antibodies Research #RNA and protein synthesis mechanisms #RNA Research and Splicing #Biology #Ribonucleoprotein #Peptide sequence #Intron #Molecular biology #Complementary DNA #Epitope #Exon #Amino acid #Consensus sequence #RNA #Genetics #Gene #Antigen
26. Human Apolipoprotein D Gene: Gene Sequence, Chromosome Localization, and Homology to the α 2u -Globulin Superfamily
    1987/06/01 by Dennis Drayna, John W. McLean, Karen L. Wion +3 · 5 citations
    Medicine · Biochemistry, Genetics and Molecular Biology · #Blood Coagulation and Thrombosis Mechanisms #Protease and Inhibitor Mechanisms #Cell Adhesion Molecules Research #Gene #Homology (biology) #Intron #Exon #Genetics #Biology #Coding region #Untranslated region #Molecular biology #Messenger RNA
27. Structure, evolution, and polymorphisms of the human apolipoprotein A4 gene (APOA4).
    1986/11/01 by Sotirios K. Karathanasis, Peter Oettgen, I. Aiza Haddad +1 · 1 citation
    Biochemistry, Genetics and Molecular Biology · Medicine · #Metabolism and Genetic Disorders #Folate and B Vitamins Research #Peroxisome Proliferator-Activated Receptors #Genetics #Intron #Gene #Biology #Coding region
28. Comparison of the human apolipoprotein genes
    1985/11/01 by C.Simon Shelley, Chris Shelley, Colin R. Sharpe +3 · 2 citations
    Biochemistry, Genetics and Molecular Biology · #Amino acid #Biology #Conserved sequence #Exon #Function (biology) #Gene #Genetics #Homologous chromosome #Intron #Molecular biology #Peptide sequence #Peroxisome Proliferator-Activated Receptors #RNA Research and Splicing #RNA modifications and cancer #Sequence (biology)
29. The human apolipoprotein A-II gene: complete nucleic acid sequence and genomic organization
    1985/01/01 by Karl J. Lackner, S W Law, H. Bryan Brewer · 1 citation
    Biochemistry, Genetics and Molecular Biology · #Peroxisome Proliferator-Activated Receptors #RNA and protein synthesis mechanisms #RNA Research and Splicing #Biology #Genetics #Gene #genomic DNA #Molecular biology #Intron #Restriction fragment length polymorphism #Restriction fragment #Nucleic acid #DNA #Restriction map #Nucleic acid sequence #Polymerase chain reaction
30. Isolation and Sequence Analysis of the Human Apolipoprotein CIII Gene and the Intergenic Region between the Apo AI and Apo CIII Genes
    1984/12/01 by Andrew A. Protter, Beatriz Levy-Wilson, J. S. Miller +3 · 1 citation
    Medicine · Biochemistry, Genetics and Molecular Biology · #Diabetes, Cardiovascular Risks, and Lipoproteins #Peroxisome Proliferator-Activated Receptors #Lipoproteins and Cardiovascular Health #Intergenic region #Gene #Genetics #Biology #Coding region #Apolipoprotein B #Intron #Sequence analysis #Apolipoprotein C2 #Nucleic acid sequence #Sequence (biology) #DNA #Molecular biology #Lipoprotein #Genome #Biochemistry #Very low-density lipoprotein

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