- Prefusion-specific glycoprotein B human antibodies protect against neonatal HSV-2 infection
2026/02/24 by Parastoo Amlashi, JeongRyeol Kim, Nisali N. Mendis +11 · 1 voice · 1 citation
Biochemistry, Genetics and Molecular Biology · Medicine · #Antibody #Cytomegalovirus and herpesvirus research #Epitope #Glycoprotein #Herpes simplex virus #Herpesvirus Infections and Treatments #Immune system #Monoclonal antibody #Neutralizing antibody #Virus #Virus-based gene therapy research
- Neutralizing antibodies protect mice against Venezuelan equine encephalitis virus aerosol challenge
2022/03/17 by Natasha M. Kafai, Lauren E. Williamson, Elad Binshtein +14 · 20 citations
Medicine · #Alphavirus #Antibody #Antigen #Biology #Epitope #Immunology #Monoclonal antibody #Mosquito-borne diseases and control #Venezuelan equine encephalitis virus #Viral Infections and Vectors #Virology #Virology and Viral Diseases #Virus
- SARS-CoV-2 T Cell Responses Elicited by COVID-19 Vaccines or Infection Are Expected to Remain Robust against Omicron
2022/01/02 by Syed Faraz Ahmed, Ahmed Abdul Quadeer, Matthew R. McKay · 2 citations
Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · Medicine · #Antibody #Biology #Cell #Coronavirus disease 2019 (COVID-19) #Disease #Epitope #Genetics #Immune system #Immunology #Immunotherapy and Immune Responses #Infectious disease (medical specialty) #Medicine #SARS-CoV-2 and COVID-19 Research #Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) #T cell #Virology #vaccines and immunoinformatics approaches
- Striking antibody evasion manifested by the Omicron variant of SARS-CoV-2
2021/12/23 by Lihong Liu, Sho Iketani, Yicheng Guo +20 · 6 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Antibody #Biology #COVID-19 Clinical Research Studies #Coronavirus disease 2019 (COVID-19) #Disease #Epitope #Immunology #Infectious disease (medical specialty) #Medicine #Monoclonal antibody #Neutralization #SARS-CoV-2 and COVID-19 Research #Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) #Spike Protein #Virology #vaccines and immunoinformatics approaches
- Immunogenicity of Recombinant-Deficient Lactobacillus casei with Complementary Plasmid Expressing Alanine Racemase Gene and Core Neutralizing Epitope Antigen against Porcine Epidemic Diarrhea Virus
2021/09/26 by Fengsai Li, Xiaona Wang, Xiaolong Fan +8 · 1 voice · 4 citations
Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · Medicine · #Animal Virus Infections Studies #Antibody #Antigen #Bacteria #Biology #Epitope #Gene #Immune system #Immunogenicity #Immunology #Lactobacillus casei #Microbiology #Plasmid #Porcine epidemic diarrhea virus #Recombinant DNA #Viral gastroenteritis research and epidemiology #Virology #Virus #Virus-based gene therapy research
- Downregulation of G3BP2 reduces atherosclerotic lesions in ApoE mice
2020/08/26 by Tianhan Li, Maharani Safitri, Kang Zhang +8 · 14 citations
Immunology and Microbiology · Medicine · #Antibody #Apolipoprotein E #Atherosclerosis and Cardiovascular Diseases #Biochemistry #Biology #Cytokine Signaling Pathways and Interactions #Disease #Downregulation and upregulation #Endocrinology #Epitope #Immune Response and Inflammation #Immune system #Immunization #Immunology #Inflammation #Internal medicine #Keyhole limpet hemocyanin #Medicine
- Evidence That Pathogenic Transglutaminase 2 in Celiac Disease Derives From Enterocytes
2020/04/14 by Rasmus Iversen, Sunniva F. Amundsen, Liv Kleppa +4 · 25 citations
Medicine · Veterinary · #Animal health and immunology #Antibody #Antigen #Autoantibody #Biochemistry #Biology #Celiac Disease Research and Management #Disease #Enzyme #Epitope #Gluten #Immune system #Immunology #Medicine #Pancreatitis Pathology and Treatment #Pathogenesis #Pathology #Tissue transglutaminase
- Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein
2020/03/09 by Alexandra C. Walls, Young‐Jun Park, Young-Jun Park +4 · 77 citations
Agricultural and Biological Sciences · Medicine · #Animal Virus Infections Studies #Antibody #Antigenicity #Biochemistry #Biogenesis #Biology #Cell biology #Coronavirus #Coronavirus disease 2019 (COVID-19) #Ectodomain #Epitope #Furin #Gene #Genetics #Glycoprotein #Immunogen #Molecular biology #Monoclonal antibody #Polyclonal antibodies #Receptor #SARS-CoV-2 and COVID-19 Research #Viral Infections and Outbreaks Research #Viral entry #Viral replication #Virology #Virus
- Biotinylated Oligo-α-(1 → 4)-d-galactosamines and Their N-Acetylated Derivatives: α-Stereoselective Synthesis and Immunology Application
2020/01/08 by Ekaterina D. Kazakova, Ekaterina Kazakova, Dmitry V. Yashunsky +9 · 20 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Antibody #Antifungal resistance and susceptibility #Antigen #Aspergillus fumigatus #Biochemistry #Biotin #Biotinylation #Carbohydrate Chemistry and Synthesis #Chemistry #Epitope #Glycoconjugate #Glycoprotein #Glycosyl #Glycosylation #Glycosylation and Glycoproteins Research #Immunology #Microbiology #Molecular biology #Monoclonal antibody #Stereochemistry #Streptavidin
- Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo
2017/08/28 by Max Medina-Ramírez, Fernando Garcés, Fernando Garces +35 · 30 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Immunology and Microbiology · Medicine · #Antibody #Biochemistry #Biology #Cell biology #Chemistry #Epitope #Genetics #Glycoprotein #Glycosylation and Glycoproteins Research #Gp41 #HIV Research and Treatment #Immunology #In vitro #In vivo #Molecular biology #Monoclonal and Polyclonal Antibodies Research #Neutralizing antibody #Trimer #Virology
- MultiTEP platform-based DNA epitope vaccine targeting N-terminus of tau induces strong immune responses and reduces tau pathology in THY-Tau22 mice
2017/03/18 by Hayk Davtyan, Wesley W. Chen, Karen Zagorski +8 · 17 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Alzheimer's disease research and treatments #Antibody #Biology #DNA vaccination #Disease #ELISPOT #Epitope #Genetically modified mouse #Immune system #Immunization #Immunohistochemistry #Immunology #Medicinal Plants and Neuroprotection #Medicine #Neurodegeneration #Pathology #T cell #Tauopathy #Transgene #Transgenic Plants and Applications #Vaccination
- The oligodendrocyte‐specific antibody ‘CC1’ binds Quaking 7
2016/07/25 by Jenea M. Bin, Stephanie N. Harris, Timothy E. Kennedy · 28 citations
Biochemistry, Genetics and Molecular Biology · #Adenomatous polyposis coli #Antibody #Antigen #Biochemistry #Biology #Cancer #Central nervous system #DNA #Epitope #Gene #Genetics #Immunology #Molecular biology #Monoclonal antibody #Myelin #Oligodendrocyte #RNA #RNA Research and Splicing #RNA modifications and cancer #RNA-binding protein #Signaling Pathways in Disease #clone (Java method)
- Unique potential of 4-1BB agonist antibody to promote durable regression of HPV + tumors when combined with an E6/E7 peptide vaccine
2015/09/08 by Todd Bartkowiak, Shailbala Singh, Guojun Yang +6 · 26 citations
Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · Medicine · #Agonist #Antibody #Cancer #Cancer Immunotherapy and Biomarkers #Cancer research #Cervical cancer #Epitope #HPV infection #HPV vaccines #Immune system #Immunology #Immunotherapy #Immunotherapy and Immune Responses #Internal medicine #Medicine #Oncology #Peptide vaccine #Receptor #Vaccination #vaccines and immunoinformatics approaches
- Significance of the Evolutionary α1,3-Galactosyltransferase (GGTA1) Gene Inactivation in Preventing Extinction of Apes and Old World Monkeys
2014/10/14 by Uri Galili · 28 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Animal Genetics and Reproduction #Antibody #Biological evolution #Biology #Epitope #Evolutionary biology #Gene #Genetics #Hominidae #Old World #Phylogenetics #Primate #Virus-based gene therapy research #Xenotransplantation and immune response #Zoology
- Novel antibody binding determinants on the capsid surface of serotype O foot-and-mouth disease virus
2014/03/01 by Amin S. Asfor, Sasmita Upadhyaya, Nick J. Knowles +3 · 16 citations
Agricultural and Biological Sciences · Medicine · #Amino acid #Animal Disease Management and Epidemiology #Antibody #Antigen #Antiserum #Aphthovirus #Biology #Capsid #Epitope #Foot-and-mouth disease virus #Gene #Genetics #Monoclonal antibody #Mutant #Neutralization #Neutralizing antibody #Serotype #Vector-Borne Animal Diseases #Viral Infections and Immunology Research #Virology #Virus
- Antibodies to a Single, Conserved Epitope in Anopheles APN1 Inhibit Universal Transmission of Plasmodium falciparum and Plasmodium vivax Malaria
2013/12/10 by Jennifer S. Armistead, Isabelle Morlais, Derrick Mathias +13 · 25 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Anopheles #Antibody #Apicomplexa #Biology #Epitope #Immunology #Malaria #Malaria Research and Control #Mosquito-borne diseases and control #Parasite hosting #Plasmodium (life cycle) #Plasmodium falciparum #Plasmodium vivax #Transmission (telecommunications) #Vibrio bacteria research studies #Virology
- Engineering HIV envelope protein to activate germline B cell receptors of broadly neutralizing anti-CD4 binding site antibodies
2013/03/25 by Andrew T. McGuire, Sam Hoot, Anita M. Dreyer +11 · 34 citations
Immunology and Microbiology · #AIDS Vaccines #Antibody #Biology #Epitope #Gene #Genetics #Germline #Glycoprotein #Glycosylation #Gp41 #HIV Research and Treatment #HIV vaccine #Human immunodeficiency virus (HIV) #Immune Cell Function and Interaction #Immunology #Molecular biology #Neutralizing antibody #T-cell and B-cell Immunology #Vaccine trial #Virology #Virus
- T cells induced by recombinant chimpanzee adenovirus alone and in prime‐boost regimens decrease chimeric EcoHIV/NDK challenge virus load
2012/08/29 by Yaowaluck Maprang Roshorm, Yaowaluck Roshorm, Mathew G. Cottingham +4 · 11 citations
Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · #AIDS Vaccines #Antigen #Biology #DNA vaccination #Epitope #Gene #Genetics #HIV Research and Treatment #Immune system #Immunization #Immunogenicity #Immunology #Immunotherapy and Immune Responses #Modified vaccinia Ankara #Plasmid #Recombinant DNA #Recombineering #Vaccination #Vaccine trial #Vaccinia #Virology #Virus #Virus-based gene therapy research
- ZnT8 Is a Major CD8+ T Cell–Recognized Autoantigen in Pediatric Type 1 Diabetes
2012/05/15 by Émmanuelle Énée, Emmanuelle Énée, Roland Kratzer +13 · 23 citations
Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · Medicine · #Antibody #Antigen #Autoantibody #CD8 #Diabetes and associated disorders #Diabetes mellitus #ELISPOT #Endocrinology #Epitope #Human leukocyte antigen #Immune Cell Function and Interaction #Immune system #Immunology #Medicine #Population #T cell #T-cell and B-cell Immunology #Type 1 diabetes
- Zinc transporter (ZnT)8186–194 is an immunodominant CD8+ T cell epitope in HLA-A2+ type 1 diabetic patients
2012/04/19 by M. Scotto, Matthieu Scotto, Georgia Afonso +29 · 24 citations
Biochemistry, Genetics and Molecular Biology · Medicine · Nursing · #Antibody #Antigen #Autoantibody #Autoimmunity #Biology #CD8 #Diabetes and associated disorders #Epitope #Genetics #Human leukocyte antigen #Immune system #Immunodominance #Immunology #Medicine #Pancreatic function and diabetes #Peripheral blood mononuclear cell #T cell #Trace Elements in Health
- Stiff-person syndrome (SPS) and anti-GAD-related CNS degenerations: Protean additions to the autoimmune central neuropathies
2011/06/24 by Fatima Ali, Fatima Al Ali, Merrill J. Rowley +6 · 2 citations
Chemistry · Medicine · Neuroscience · #Antibody #Autoantibody #Autoimmune Neurological Disorders and Treatments #Autoimmune disease #Autoimmunity #Biochemistry #Biology #Chemistry #Conformational epitope #Enzyme #Epitope #Genetic Neurodegenerative Diseases #Glutamate decarboxylase #Immunology #Medicine #Neurological disorders and treatments #Neuroscience #Stiff person syndrome
- Lymph node–resident lymphatic endothelial cells mediate peripheral tolerance via Aire-independent direct antigen presentation
2010/03/22 by Jarish N. Cohen, Cynthia J. Guidi, Eric F. Tewalt +8 · 32 citations
Immunology and Microbiology · Medicine · #Antigen #Antigen presentation #Antigen-presenting cell #Autoimmune regulator #Autoimmunity #Biology #CD8 #Cancer research #Cross-presentation #Epitope #Immune system #Immune tolerance #Immunology #Immunotherapy and Immune Responses #Lymph node #Lymph node stromal cell #Lymphatic Endothelium #Lymphatic System and Diseases #Lymphatic system #Peripheral tolerance #Stromal cell #T cell #T-cell and B-cell Immunology
- Biological significance of amino acid substitutions in hepatitis B surface antigen (HBsAg) for glycosylation, secretion, antigenicity and immunogenicity of HBsAg and hepatitis B virus replication
2009/10/07 by C. Wu, Chunli Wu, X. Zhang +11 · 26 citations
Immunology and Microbiology · Medicine · #Antigen #Antigenicity #Biology #Epitope #HBsAg #Hepatitis B Virus Studies #Hepatitis B virus #Hepatitis C virus research #Immunogenicity #Immunology #Immunotherapy and Immune Responses #Molecular biology #Virology #Virus
- Oxidation-specific epitopes are dominant targets of innate natural antibodies in mice and humans
2009/04/14 by Meng-Yun Chou, Linda Fogelstrand, Karsten Hartvigsen +12 · 31 citations
Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · #Acquired immune system #Antibody #Atherosclerosis and Cardiovascular Diseases #Biochemistry #Biology #Cell biology #Epitope #Homeostasis #Immune system #Immunology #Inflammasome and immune disorders #Inflammation #Innate immune system #Lipoprotein #Neutrophil, Myeloperoxidase and Oxidative Mechanisms #Pattern recognition receptor #Receptor #Scavenger receptor
- Apotopes and the biliary specificity of primary biliary cirrhosis†
2009/01/30 by Ana Lleò, Carlo Selmi, Pietro Invernizzi +7 · 1 citation
Medicine · #Liver Diseases and Immunity #Liver physiology and pathology #Drug Transport and Resistance Mechanisms #Primary biliary cirrhosis #Biology #Apoptosis #Intrahepatic bile ducts #Antibody #Immune system #Biliary cirrhosis #Epitope #Immunology #Monoclonal antibody #Isotype #Autoimmune disease #Medicine #Internal medicine #Bile duct #Genetics
- Generation and analysis of recombinant Bunyamwera orthobunyaviruses expressing V5 epitope-tagged L proteins
2009/01/13 by Xiǎohóng Shí, Xiaohong Shi, Richard M. Elliott · 7 citations
Agricultural and Biological Sciences · Medicine · #Antibody #Biochemistry #Biology #Epitope #FLAG-tag #Fusion protein #Gene #Genetics #Molecular biology #Mosquito-borne diseases and control #Myc-tag #RNA #RNA virus #Recombinant DNA #Subgenomic mRNA #Vector-Borne Animal Diseases #Vero cell #Viral Infections and Vectors #Viral replication #Virology #Virus
- Influenza virus antigenic variation, host antibody production and new approach to control epidemics
2009/01/01 by Jiezhong Chen, Yi‐Mo Deng · 1 citation
Medicine · Agricultural and Biological Sciences · #Influenza Virus Research Studies #Respiratory viral infections research #Animal Disease Management and Epidemiology #Virology #Biology #Antigenic drift #Antigenicity #Antigenic shift #Antigen #Hemagglutinin (influenza) #Virus #Original antigenic sin #Antibody #Neuraminidase #Monoclonal antibody #Antigenic variation #H5N1 genetic structure #Epitope #Vaccination #Microbiology #Immunology #Infectious disease (medical specialty) #Disease #Coronavirus disease 2019 (COVID-19) #Medicine
- Clonally expanded plasma cells in the cerebrospinal fluid of MS patients produce myelin‐specific antibodies
2008/06/03 by H.‐Christian von Büdingen, Hans‐Christian von Büdingen, Melanie D. Harrer +4 · 26 citations
Immunology and Microbiology · Medicine · #Antibody #Antigen #Biology #Central nervous system #Cerebrospinal fluid #Epitope #Immunofluorescence #Immunology #Medicine #Molecular biology #Monoclonal antibody #Multiple Sclerosis Research Studies #Multiple sclerosis #Myelin #Pathology #Systemic Lupus Erythematosus Research #T-cell and B-cell Immunology #White matter
- PEPITO: improved discontinuous B-cell epitope prediction using multiple distance thresholds and half sphere exposure
2008/04/28 by Michael J. Sweredoski, Pierre Baldi · 2 citations
Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · #vaccines and immunoinformatics approaches #Immunotherapy and Immune Responses #Machine Learning in Bioinformatics #Epitope #Benchmark (surveying) #Computer science #Computational biology #Antigen #Artificial intelligence #Biology #Immunology
- 2S Albumin Storage Proteins: What Makes them Food Allergens?
2008/02/06 by F. Javier Moreno, Alfonso Clemente · 1 citation
Medicine · Chemistry · #Food Allergy and Anaphylaxis Research #Allergic Rhinitis and Sensitization #Contact Dermatitis and Allergies #Epitope #Ovalbumin #Food allergy #Immune system #Immunoglobulin E #Storage protein #Chemistry #Allergic response #Albumin #Gastrointestinal tract #Biology #Immunology #Allergy #Biochemistry #Antibody
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