- Intermolecular 3′UTR-3′UTR interactions drive Wnt gene activation through heteromeric protein assembly
2026/05/07 by Ting Cai, Nelly M. Cruz, Sudipto Basu +2 · 1 voice · 1 citation
Biochemistry, Genetics and Molecular Biology · #Biogenesis #Developmental Biology and Gene Regulation #Gene expression #Messenger RNA #Regulation of gene expression #Skin and Cellular Biology Research #Transcription (linguistics) #Transcription factor #Wnt signaling pathway #Wnt/β-catenin signaling in development and cancer #Zebrafish
- Synchronous spatio-temporal control of autophagy and organelle trafficking is necessary for appressorium-mediated plant infection by Magnaporthe oryzae
2025/10/06 by Alice Bisola Eseola, Yan Xia, Míriam Osés-Ruiz +4 · 1 voice · 1 citation
Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · #Appressorium #Autophagy #Biogenesis #Cell #Organelle #Organelle biogenesis #Plant Pathogenic Bacteria Studies #Plant Pathogens and Fungal Diseases #Plant-Microbe Interactions and Immunity #Programmed cell death #Vacuole
- Lipid droplets: Open questions and conceptual advances around a unique organelle
2025/08/28 by W. Mike Henne, Emma Reynolds, William A. Prinz · 1 voice · 1 citation
Biochemistry, Genetics and Molecular Biology · Medicine · #Adipose Tissue and Metabolism #Biogenesis #Lipid droplet #Lipid metabolism #Lipid metabolism and biosynthesis #Organelle #Organelle biogenesis #Plant biochemistry and biosynthesis
- Lactylation stabilizes TFEB to elevate autophagy and lysosomal activity
2024/04/04 by Yewei Huang, Gan Luo, Kesong Peng +13 · 25 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Autophagy #Autophagy in Disease and Therapy #Basic helix-loop-helix leucine zipper transcription factors #Biochemistry #Biogenesis #Biology #Cell biology #Cellular transport and secretion #Chemistry #DNA-binding protein #Enzyme #Gene #Lysosome #Proteasome #Regulator #TFEB #Transcription factor #Ubiquitin #Ubiquitin and proteasome pathways #Ubiquitin ligase #Ubiquitin-Protein Ligases
- Rescue of Mitochondrial Function in Hutchinson-Gilford Progeria Syndrome by the Pharmacological Modulation of Exportin CRM1
2023/01/10 by Feliciano Monterrubio-Ledezma, Fernando Navarro‐García, Lourdes Massieu +4 · 1 citation
Biochemistry, Genetics and Molecular Biology · Nursing · #Nuclear Structure and Function #Mitochondrial Function and Pathology #Trace Elements in Health #Progeria #Mitochondrion #Cell biology #Mitochondrial biogenesis #Biology #Mitophagy #Biogenesis #Premature aging #Lamin #Autophagy #Genetics #Gene #Nucleus #Apoptosis
- TREM2-dependent lipid droplet biogenesis in phagocytes is required for remyelination
2021/08/23 by Garyfallia Gouna, Christian Klose, Mar Bosch-Queralt +7 · 29 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Neuroscience · Pharmacology, Toxicology and Pharmaceutics · #Biochemistry #Biogenesis #Biology #Cell biology #Central nervous system #Chemistry #Endoplasmic reticulum #Immune system #Immunology #Inflammation #Innate immune system #Lipid droplet #Microglia #Myelin #Neuroinflammation and Neurodegeneration Mechanisms #Neuroscience #Pharmacological Effects of Natural Compounds #Remyelination #Sphingolipid Metabolism and Signaling #TREM2 #Unfolded protein response
- Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein
2020/03/09 by Alexandra C. Walls, Young‐Jun Park, Young-Jun Park +4 · 77 citations
Agricultural and Biological Sciences · Medicine · #Animal Virus Infections Studies #Antibody #Antigenicity #Biochemistry #Biogenesis #Biology #Cell biology #Coronavirus #Coronavirus disease 2019 (COVID-19) #Ectodomain #Epitope #Furin #Gene #Genetics #Glycoprotein #Immunogen #Molecular biology #Monoclonal antibody #Polyclonal antibodies #Receptor #SARS-CoV-2 and COVID-19 Research #Viral Infections and Outbreaks Research #Viral entry #Viral replication #Virology #Virus
- Plant Selective Autophagy—Still an Uncharted Territory With a Lot of Hidden Gems
2019/06/28 by Madlen Stephani, Yasin Dagdas · 30 citations
Agricultural and Biological Sciences · Medicine · Neuroscience · #Arabidopsis #Autophagosome #Autophagy #Autophagy in Disease and Therapy #Biogenesis #Biology #Cell biology #Computational biology #Gene #Genetics #Neuroscience #Plant Parasitism and Resistance #Plant-Microbe Interactions and Immunity
- Mitochondrial NCKX5 regulates melanosomal biogenesis and pigment production
2019/06/14 by Zhao Zhang, Juanjuan Gong, Elena V. Sviderskaya +2 · 26 citations
Biochemistry, Genetics and Molecular Biology · Nursing · #Biochemical Analysis and Sensing Techniques #Biochemistry #Biogenesis #Biology #Cell biology #Gene #Mitochondrial biogenesis #Mitochondrion #Pigment #Retinal Development and Disorders #melanin and skin pigmentation
- Amyloid assembly and disassembly
2018/04/13 by Edward Chuang, Acacia M. Hori, Acacia M Hori +2 · 25 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Alzheimer's disease research and treatments #Amyloid (mycology) #Amyloid disease #Amyloid fibril #Amyloid β #Amyotrophic Lateral Sclerosis Research #Autophagy #Biochemistry #Biogenesis #Biology #Cell biology #Disease #Fibril #Internal medicine #Medicine #Prion Diseases and Protein Misfolding #Proteasome #Protein aggregation #Protein folding
- UsnRNP biogenesis: mechanisms and regulation
2017/08/01 by Oliver J. Gruss, Oliver J. Gruß, Rajyalakshmi Meduri +2 · 26 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Biochemistry #Biogenesis #Biology #Cancer-related gene regulation #Cell biology #Computational biology #Function (biology) #Gene #Neurogenetic and Muscular Disorders Research #RNA Research and Splicing
- TFEB at a glance
2016/06/02 by Gennaro Napolitano, Andrea Ballabio · 37 citations
Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · Medicine · Neuroscience · #Autophagy #Autophagy in Disease and Therapy #Basic helix-loop-helix leucine zipper transcription factors #Biochemistry #Biogenesis #Biology #Cell biology #Cellular transport and secretion #DNA-binding protein #Gene #Lysosome #Mechanistic target of rapamycin #Neuroscience #PI3K/AKT/mTOR pathway #Plant Molecular Biology Research #Signal transduction #TFEB #Transcription factor
- The role of plastoglobules in thylakoid lipid remodeling during plant development
2015/02/07 by Sarah Rottet, Céline Besagni, Félix Kessler +1 · 29 citations
Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · #Biochemistry #Biogenesis #Biology #Cell biology #Chloroplast #Chloroplast membrane #Lipid metabolism and biosynthesis #Photosynthetic Processes and Mechanisms #Plant Molecular Biology Research #Thylakoid #Twin-arginine translocation pathway
- The ER-Golgi intermediate compartment feeds the phagophore membrane
2013/11/11 by Liang Ge, Randy Schekman · 1 citation
Medicine · Biochemistry, Genetics and Molecular Biology · #Autophagy in Disease and Therapy #Calcium signaling and nucleotide metabolism #Cellular transport and secretion #Autophagosome #Autophagy #Lipid-anchored protein #Biogenesis #Cell biology #Biology #Compartment (ship) #ATG8 #Golgi apparatus #Organelle #Biochemistry #Endoplasmic reticulum
- 4-thiouridine inhibits rRNA synthesis and causes a nucleolar stress response
2013/09/11 by Kaspar Burger, Bastian Mühl, Markus Kellner +6 · 4 citations
Biochemistry, Genetics and Molecular Biology · #RNA modifications and cancer #RNA and protein synthesis mechanisms #RNA Research and Splicing #Ribosome biogenesis #Biology #Nucleophosmin #Ribosomal RNA #Nucleolus #RNA #Ribonucleoside #Ribosome #Protein biosynthesis #Cell biology #Molecular biology #Messenger RNA #Biogenesis #Biochemistry #Gene #Cytoplasm
- Exosomes: Looking back three decades and into the future
2013/02/18 by Clifford V. Harding, John E. Heuser, Philip D. Stahl · 28 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Biogenesis #Biology #Cell biology #Endosome #Exocytosis #Extracellular vesicles #Extracellular vesicles in disease #Genetics #Intracellular #Membrane #MicroRNA in disease regulation #Microvesicles #Viral Infections and Vectors #microRNA
- A-Type Carrier Protein ErpA Is Essential for Formation of an Active Formate-Nitrate Respiratory Pathway in Escherichia coli K-12
2011/11/12 by Constanze Pinske, R. Gary Sawers · 12 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Energy · Environmental Science · #Bacterial Genetics and Biotechnology #Biochemistry #Biogenesis #Biology #Chemistry #Cofactor #Complementation #Enzyme #Formate dehydrogenase #Gene #Metalloenzymes and iron-sulfur proteins #Microbial Fuel Cells and Bioremediation #Mutant #Protein subunit #Scaffold protein #Signal transduction #Wild type
- Membrane trafficking and organelle biogenesis in Giardia lamblia: Use it or lose it
2011/02/05 by Carmen Faso, Adrian B. Hehl · 20 citations
Immunology and Microbiology · Medicine · #Biochemistry #Biogenesis #Biology #Cell biology #Endoplasmic reticulum #Gene #Giardia #Giardia lamblia #Golgi apparatus #Membrane #Microbiology #Organelle #Organelle biogenesis #Parasitic Infections and Diagnostics #Parasitic infections in humans and animals #Toxoplasma gondii Research Studies #Vesicle
- FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end–directed vesicle transport
2010/01/25 by Serhiy Pankiv, Endalkachew A. Alemu, Andreas Brech +6 · 33 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Autophagy #Autophagy in Disease and Therapy #Biochemistry #Biogenesis #Biology #Cell biology #Cellular transport and secretion #Cytosol #Effector #Endoplasmic Reticulum Stress and Disease #Membrane #Microtubule #Organelle #Phosphatidylinositol #Signal transducing adaptor protein #Signal transduction #Transport protein #Vesicle #Vesicular transport protein
- Evolution, biogenesis and function of promoter-associated RNAs
2009/08/01 by Ryan J. Taft, Craig D. Kaplan, Cas Simons +1 · 1 citation
Biochemistry, Genetics and Molecular Biology · #Biogenesis #Biology #Cancer-related molecular mechanisms research #Cell biology #Chromatin #Gene #Gene expression #General transcription factor #Genetics #Nucleosome #Promoter #RNA Research and Splicing #RNA modifications and cancer #RNA polymerase II #Transcription (linguistics) #Transcription preinitiation complex
- ABCA1 Promotes the de Novo Biogenesis of Apolipoprotein CIII-Containing HDL Particles in Vivo and Modulates the Severity of Apolipoprotein CIII-Induced Hypertriglyceridemia
2008/09/04 by Kyriakos E. Kypreos · 1 citation
Medicine · Biochemistry, Genetics and Molecular Biology · Chemistry · #Cholesterol and Lipid Metabolism #Lipid metabolism and disorders #Cancer, Lipids, and Metabolism #Apolipoprotein B #Hypertriglyceridemia #Biogenesis #Apolipoprotein C2 #In vivo #Chemistry #Cholesterol #Internal medicine #Medicine #Biology #Biochemistry #Lipoprotein #Very low-density lipoprotein #Triglyceride #Genetics #Gene
- Chapter 6 Phagocytosis and Host–Pathogen Interactions in Dictyostelium with a Look at Macrophages
2008/01/01 by Salvatore Bozzaro, Cecilia Bucci, Michael Steinert · 1 citation
Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · #Biogenesis #Biology #Cell biology #Cellular transport and secretion #Dictyostelium #Dictyostelium discoideum #Eukaryote #Gene #Genetics #Genome #Model organism #Pathogen #Phagocytosis #Phagocytosis and Immune Regulation #Phagosome #Vibrio bacteria research studies
- Functional domain mapping of peroxin Pex19p: interaction with Pex3p is essential for function and translocation
2006/08/09 by Yuji Matsuzono, Takashi Matsuzaki, Yukio Fujiki · 18 citations
Biochemistry, Genetics and Molecular Biology · #Biochemistry #Biogenesis #Biology #Cell biology #Chaperone (clinical) #Cytosol #Enzyme #Gene #Membrane #Membrane protein #Mutant #Peptide sequence #Peroxisomal targeting signal #Peroxisome #Peroxisome Proliferator-Activated Receptors #Protein targeting #RNA Research and Splicing #Receptor #Signaling Pathways in Disease #Transport protein
- A Macromolecular Complex Formed by a Pilin-like Protein in Competent Bacillus subtilis
2006/06/03 by Inês Chen, Roberta Provvedi, David Dubnau · 29 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Environmental Science · #Bacillus subtilis #Bacterial Genetics and Biotechnology #Bacteriophages and microbial interactions #Biochemistry #Biogenesis #Biology #Biophysics #Cell biology #Chemistry #DNA #Escherichia coli #Gene #Genetics #Pilin #Pilus #Protein subunit #RNA and protein synthesis mechanisms
- A Comparative Categorization of Protein Function Encoded in Bacterial or Archeal Genomic Islands
2005/12/06 by Rainer Merkl · 9 citations
Biochemistry, Genetics and Molecular Biology · #Bacterial Genetics and Biotechnology #Biogenesis #Biology #Cog #Computational biology #Escherichia coli #Gene #Genetics #Genome #Genomics and Phylogenetic Studies #Horizontal gene transfer #Operon #RNA and protein synthesis mechanisms #Translation (biology)
- Formation of stacked ER cisternae by low affinity protein interactions
2003/10/27 by Erik L. Snapp, Ramanujan S. Hegde, Maura Francolini +6 · 29 citations
Biochemistry, Genetics and Molecular Biology · #Antiparallel (mathematics) #Biochemistry #Biogenesis #Biology #Cell biology #Cellular transport and secretion #Cytoplasm #Endoplasmic reticulum #Fluorescence recovery after photobleaching #Gene #Green fluorescent protein #Membrane #Membrane protein #Microtubule and mitosis dynamics #Photosynthetic Processes and Mechanisms #Unfolded protein response
- Alzheimer's disease: the cholesterol connection
2003/03/26 by Luigi Puglielli, Rudolph E. Tanzi, Dora M. Kovacs · 5 citations
Medicine · Neuroscience · #Alzheimer's disease #Alzheimer's disease research and treatments #Amyloid beta #Amyloid precursor protein #Apolipoprotein B #Apolipoprotein E #Biogenesis #Bioinformatics #Biology #Cholesterol #Cholesterol and Lipid Metabolism #Disease #Endocrinology #Gene #Genetics #Internal medicine #Lipoproteins and Cardiovascular Health #Medicine #Neuroscience #Pathogenesis
- Structure of eukaryotic prefoldin and of its complexes with unfolded actin and the cytosolic chaperonin CCT
2002/11/27 by Jaime Martín‐Benito, Jasminka Boskovic, Paulino Gómez‐Puertas +6 · 4 citations
Biochemistry, Genetics and Molecular Biology · Materials Science · #Actin #Biochemistry #Biogenesis #Biology #Biophysics #Cell #Cell biology #Chaperonin #Cytoskeleton #Cytosol #Enzyme Structure and Function #Heat shock proteins research #Microtubule #Protein Structure and Dynamics #Protein folding #Tubulin
- The glycine decarboxylase system: a fascinating complex
2001/04/01 by Roland Douce, Jacques Bourguignon, Michel Neuburger +1 · 2 citations
Biochemistry, Genetics and Molecular Biology · Materials Science · #Amino acid #Aromatic L-amino acid decarboxylase #Biochemical Acid Research Studies #Biochemistry #Biogenesis #Biology #Cofactor #Enzyme #Enzyme Structure and Function #Gene #Glycine #Glycine cleavage system #Lipoic acid #Metabolism and Genetic Disorders #Mitochondrial matrix #Peroxisome #Photorespiration #Serine #Serine hydroxymethyltransferase
- Structure and functions of nucleolin
1999/03/15 by Hervé Ginisty, Hélène Sicard, Benoit Roger +2 · 29 citations
Biochemistry, Genetics and Molecular Biology · #Biogenesis #Biology #Cell biology #Chromatin #Cytoplasm #Gene #Genetics #Genomics and Chromatin Dynamics #Nucleolin #Nucleolus #RNA #RNA and protein synthesis mechanisms #RNA modifications and cancer #Ribosomal protein #Ribosome #Ribosome biogenesis
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