1. LBR and LAP2 mediate heterochromatin tethering to the nuclear periphery to preserve genome homeostasis
   2026/02/24 by Renard TM Lewis, Virginia Sinigiani, Noura Maziak +10 · 1 voice · 2 citations
   Biochemistry, Genetics and Molecular Biology · #Chromatin #Epigenetics #Euchromatin #Genomics and Chromatin Dynamics #Heterochromatin #Heterochromatin protein 1 #Lamin #Nuclear Structure and Function #Tethering #Virus-based gene therapy research
2. Acetylation of H3K115 is associated with fragile nucleosomes at CpG island promoters and active regulatory sites
   2026/02/17 by Yatendra Kumar, Dipta Sengupta, Elias T. Friman +7 · 1 voice · 1 citation
   Biochemistry, Genetics and Molecular Biology · #Acetylation #Chromatin #CpG site #Epigenetics and DNA Methylation #Genetics and Neurodevelopmental Disorders #Genomics and Chromatin Dynamics #Histone #Histone H3 #Histone code #Nucleosome #Promoter
3. LINE-1 Locus Transcription Nucleates Oncogenic Chromatin Architecture
   2026/01/05 by Michael Lee, Yuannyu Zhang, Jun Yi Stanley Lim +9 · 1 voice · 2 citations
   Agricultural and Biological Sciences · Immunology and Microbiology · #Chromatin #Chromosomal and Genetic Variations #Gene #Gene expression #Genome #Locus (genetics) #RNA #Regulation of gene expression #Retrotransposon #T-cell and Retrovirus Studies #Transcription (linguistics) #interferon and immune responses
4. Two distinct chromatin modules regulate proinflammatory gene expression
   2025/12/24 by Isabelle Seufert, Irene Gerosa, Vassiliki Varamogianni-Mamatsi +12 · 1 voice · 2 citations
   Biochemistry, Genetics and Molecular Biology · #ChIA-PET #Chromatin #Chromatin remodeling #Epigenetics and DNA Methylation #Gene expression #Genomics and Chromatin Dynamics #Proinflammatory cytokine #Regulation of gene expression #Single-cell and spatial transcriptomics #Transcription factor
5. Mapping chromatin structure at base-pair resolution unveils a unified model of cis-regulatory element interactions
   2025/11/05 by Hangpeng Li, James Dalgleish, George Lister +22 · 1 voice · 8 citations
   Biochemistry, Genetics and Molecular Biology · #Chromatin #Chromosome conformation capture #DNA #DNA and Nucleic Acid Chemistry #Developmental Biology and Gene Regulation #Eukaryotic transcription #Genomics and Chromatin Dynamics #Nucleosome #Resolution (logic) #Transcription (linguistics) #Transcription factor #Unified Model
6. Cryo-EM reveals open and closed Asgard chromatin assemblies
   2025/10/28 by Harsh Ranawat, Marc K M Cajili, Natalia Lopez‐Barbosa +3 · 1 voice · 5 citations
   Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · #Acetylation #Advanced Electron Microscopy Techniques and Applications #ChIA-PET #Chromatin #Chromatin remodeling #Chromosomal and Genetic Variations #Genomics and Chromatin Dynamics #Histone
7. HP1 loses its chromatin clustering and phase separation function across evolution
   2025/07/10 by Sanâa Bensaha, Dominika Lewandowska, Fernando Muzzopappa +6 · 1 voice · 7 citations
   Biochemistry, Genetics and Molecular Biology · Chemistry · #Artificial intelligence #Biology #Cell biology #Chemistry #Chromatin #Cluster analysis #Computational biology #Computer science #DNA #Function (biology) #Genetics #Genomics and Chromatin Dynamics #Machine learning #Phase (matter) #RNA Research and Splicing #RNA modifications and cancer #Separation (statistics)
8. Micronuclear collapse from oxidative damage
   2024/08/29 by Melody Di Bona, Yanyang Chen, Albert S. Agustinus +35 · 29 citations
   Biochemistry, Genetics and Molecular Biology · Chemistry · #Biochemistry #Biology #Cell biology #Chemistry #Chromatin #Cytosol #DNA #ESCRT #Endosome #Intracellular #Micronucleus test #Microtubule and mitosis dynamics #Mitochondrial Function and Pathology #Mitochondrion #Nuclear Structure and Function #Reactive oxygen species
9. Heterozygous deletion of the autism-associated gene CHD8 impairs synaptic function through widespread changes in gene expression and chromatin compaction
   2023/10/01 by Xi Shi, Congyi Lu, Alba Corman +8 · 12 citations
   Biochemistry, Genetics and Molecular Biology · Neuroscience · #Autism Spectrum Disorder Research #Biology #CRISPR and Genetic Engineering #Chromatin #Chromodomain #Exome sequencing #Gene #Genetics #Genomics and Chromatin Dynamics #Mutation #Neuroscience
10. Histone Acetyltransferases p300 and CBP Coordinate Distinct Chromatin Remodeling Programs in Vascular Smooth Muscle Plasticity
    2022/06/06 by Raja Chakraborty, Allison C. Ostriker, Yi Xie +14 · 27 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Acetylation #Biology #Cancer research #Cell biology #Chromatin #Chromatin immunoprecipitation #Chromatin remodeling #Endocrinology #Epigenetics #Epigenetics and DNA Methylation #Gene #Gene expression #Gene knockdown #Genetics #Histone #Histone Acetyltransferases #Histone H4 #Internal medicine #Kruppel-like factors research #Medicine #Molecular biology #Neointima #P300-CBP Transcription Factors #Promoter #Protein Degradation and Inhibitors #Vascular smooth muscle
11. Biophysics of Chromatin Remodeling
    2021/01/05 by Ilana M. Nodelman, Gregory D. Bowman · 1 citation
    Biochemistry, Genetics and Molecular Biology · #Biology #Cell biology #Chromatin #Chromatin Remodeling and Cancer #Chromatin remodeling #Computational biology #DNA #Epigenetics #Epigenetics and DNA Methylation #Gene #Genetics #Genomics and Chromatin Dynamics #Helicase #Histone #Nucleosome #RNA
12. Emerging Properties and Functions of Actin and Actin Filaments Inside the Nucleus
    2020/12/07 by Svenja Ulferts, Bina Prajapati, Robert Grosse +1 · 1 citation
    Biochemistry, Genetics and Molecular Biology · #RNA Research and Splicing #Nuclear Structure and Function #Genomics and Chromatin Dynamics #Biology #Actin #Nucleus #Actin remodeling #Cell biology #Cytoskeleton #Chromatin #Formins #Genome #Cell nucleus #Compartment (ship) #Actin cytoskeleton #Cell #Genetics #Gene
13. Candidate silencer elements for the human and mouse genomes
    2020/02/26 by Naresh Doni Jayavelu, Ajay Jajodia, Arpit Mishra +1 · 3 citations
    Biochemistry, Genetics and Molecular Biology · #Biology #Chromatin #Computational biology #Enhancer #Gene #Gene expression #Gene silencing #Genetics #Genome #Genomics and Chromatin Dynamics #Promoter #RNA Research and Splicing #RNA and protein synthesis mechanisms #Silencer
14. Islet-specific Prmt5 excision leads to reduced insulin expression and glucose intolerance in mice
    2019/09/20 by Jian Ma, Xin He, Yan Cao +10 · 10 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Beta cell #Biology #Cancer-related gene regulation #Cell biology #Chromatin #Endocrinology #Epigenetics and DNA Methylation #Gene #Gene expression #Genetics #Glucose homeostasis #Histone #Histone methyltransferase #Insulin #Insulin resistance #Internal medicine #Islet #Medicine #Methylation #Methyltransferase #Pancreatic function and diabetes #Protein arginine methyltransferase 5
15. Enhanced nuclear protein export in premature aging and rescue of the progeria phenotype by modulation of CRM1 activity
    2019/07/15 by Ian García‐Aguirre, Alma Alamillo‐Iniesta, Ruth Rodríguez‐Pérez +11 · 1 citation
    Biochemistry, Genetics and Molecular Biology · #Biology #Cell biology #Cell nucleus #Chromatin #Gene #Genetics #Heterochromatin #LMNA #Lamin #Nuclear Structure and Function #Nuclear export signal #Nuclear lamina #Nuclear protein #Nucleus #Phenotype #Premature aging #Progeria #RNA Research and Splicing #Retinoids in leukemia and cellular processes #Senescence #Transcription factor
16. Histones predate the split between bacteria and archaea
    2018/12/05 by Vikram Alva, Andrei N. Lupas · 1 citation
    Biochemistry, Genetics and Molecular Biology · #Bacterial Genetics and Biotechnology #Genomics and Chromatin Dynamics #Protist diversity and phylogeny #Histone #Biology #Archaea #Nucleosome #Histone-modifying enzymes #Genetics #Histone code #Chromatin #DNA #Evolutionary biology #Computational biology #Gene
17. Chromatin remodelers couple inchworm motion with twist-defect formation to slide nucleosomal DNA
    2018/11/05 by Giovanni B. Brandani, Shoji Takada · 1 citation
    Biochemistry, Genetics and Molecular Biology · #Advanced biosensing and bioanalysis techniques #Biology #Biophysics #Cell biology #Chromatin #Chromatin remodeling #Computational biology #DNA #DNA replication #Gene #Genetics #Genomics and Chromatin Dynamics #Nucleosome #RNA Interference and Gene Delivery #Translocase
18. Chromatin Regulation of Neuronal Maturation and Plasticity
    2018/03/09 by David A. Gallegos, Urann Chan, Liang-Fu Chen +2 · 2 citations
    Biochemistry, Genetics and Molecular Biology · Neuroscience · Psychology · #Biology #Chromatin #Developmental plasticity #Epigenetics and DNA Methylation #Gene #Genetics #Genomics and Chromatin Dynamics #Neuroplasticity #Neuroscience #Physics #Plasticity #Psychology #RNA Research and Splicing
19. Horizontal Transfer Can Drive a Greater Transposable Element Load in Large Populations
    2016/08/24 by Sam B. Groth, Justin P. Blumenstiel · 7 citations
    Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · #Biology #CRISPR and Genetic Engineering #Chromatin #Chromosomal and Genetic Variations #Ectopic recombination #Euchromatin #Evolutionary biology #Gene #Genetic recombination #Genetics #Genome #Genome evolution #Heterochromatin #Mutation rate #Plant Disease Resistance and Genetics #Population #Recombination #Transposable element
20. Defining the Human Brain Proteome Using Transcriptomics and Antibody-Based Profiling with a Focus on the Cerebral Cortex
    2015/06/15 by Evelina Sjöstedt, Linn Fagerberg, Björn M. Hallström +7 · 1 citation
    Biochemistry, Genetics and Molecular Biology · Neuroscience · #RNA Research and Splicing #Single-cell and spatial transcriptomics #Bioinformatics and Genomic Networks #Transcriptome #Biology #Gene #Human brain #Computational biology #Proteome #Gene expression #Gene expression profiling #Alternative splicing #Brain atlas #Chromatin #Genetics #Neuroscience #Messenger RNA
21. Mechanisms and Consequences of Double‐Strand DNA Break Formation in Chromatin
    2015/06/03 by Wendy J. Cannan, David S. Pederson · 31 citations
    Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · #Biology #Carcinogens and Genotoxicity Assessment #Cell biology #Chromatin #Chromothripsis #DNA #DNA Repair Mechanisms #DNA damage #DNA repair #Genetics #Genome instability #Homologous recombination #Plant Genetic and Mutation Studies
22. Proteome-Wide Lysine Acetylation in Cortical Astrocytes and Alterations That Occur during Infection with Brain Parasite Toxoplasma gondii
    2015/03/18 by Anne Bouchut, Aarti Chawla, Victoria Jeffers +2 · 1 citation
    Immunology and Microbiology · Medicine · #Toxoplasma gondii Research Studies #HIV Research and Treatment #Sirtuins and Resveratrol in Medicine #Acetylation #Biology #Lysine #Proteome #Cell biology #Acetyltransferase #Toxoplasma gondii #Chromatin #Gene #Biochemistry #Amino acid #Genetics
23. Nup2 requires a highly divergent partner, NupA, to fulfill functions at nuclear pore complexes and the mitotic chromatin region
    2014/12/25 by Sarine Markossian, Subbulakshmi Suresh, Aysha H. Osmani +1 · 1 citation
    Biochemistry, Genetics and Molecular Biology · #Anaphase #Biology #Cell #Cell biology #Cell cycle #Chromatin #DNA #Gene #Genetics #Genomics and Chromatin Dynamics #Interphase #Meiosis #Microtubule and mitosis dynamics #Mitosis #Mitotic exit #Polo-like kinase #Prophase #Ubiquitin and proteasome pathways
24. Epigenetic Involvement in Hutchinson-Gilford Progeria Syndrome: A Mini-Review
    2014/01/01 by Walter Arancio, Giuseppe Pizzolanti, Swonild Ilenia Genovese +2 · 1 citation
    Biochemistry, Genetics and Molecular Biology · #Nuclear Structure and Function #RNA Research and Splicing #Genomics and Chromatin Dynamics #Progeria #LMNA #Lamin #Biology #Nuclear lamina #Premature aging #Heterochromatin #Epigenetics #Genetics #Cell biology #Chromatin #Senescence #Phenotype #Gene #Nuclear protein
25. Reduced C9orf72 gene expression in c9FTD/ALS is caused by histone trimethylation, an epigenetic event detectable in blood
    2013/10/28 by Véronique Belzil, Veronique V. Belzil, Peter Bauer +18 · 26 citations
    Medicine · #Allele #Amyotrophic Lateral Sclerosis Research #Biology #C9orf72 #Chromatin #Chromatin immunoprecipitation #Epigenetics #Gene #Gene expression #Genetics #Haploinsufficiency #Histone #Histone H3 #Molecular biology #Neurogenetic and Muscular Disorders Research #Parkinson's Disease Mechanisms and Treatments #Phenotype #Promoter #Regulation of gene expression #Trinucleotide repeat expansion
26. Serum-mediated transgenerational effects on sperm: Evidence for lamarckian inheritance?
    2013/04/01 by Yoshiyuki Seki, Roberto J. Groszmann, Yasuko Iwakiri +1 · 1 citation
    Biochemistry, Genetics and Molecular Biology · Medicine · #Epigenetics and DNA Methylation #Hemoglobinopathies and Related Disorders #Biology #Epigenetics #DNA methylation #Myofibroblast #Reprogramming #Histone #Chromatin remodeling #Fibrosis #Cancer research #Chromatin #Epigenome #Cell biology #Sperm #Endocrinology #Internal medicine #Genetics #Gene expression #Medicine #Gene
27. The chromatin insulator CTCF and the emergence of metazoan diversity
    2012/10/08 by Peter Heger, Birger Marin, Marek Bartkuhn +2 · 1 voice · 34 citations
    Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · #Bilateria #Biology #CTCF #Chromatin #Chromosomal and Genetic Variations #Developmental Biology and Gene Regulation #Evolutionary biology #Gene #Genetics #Genome #Genomics and Chromatin Dynamics #Homeobox #Hox gene #Phylogenetics #Transcription factor #Vertebrate
28. Toxoplasmahistone acetylation remodelers as novel drug targets
    2012/10/01 by Laura Vanagas, Victoria Jeffers, Silvina S. Bogado +3 · 1 citation
    Immunology and Microbiology · Medicine · #Toxoplasma gondii Research Studies #Herpesvirus Infections and Treatments #HIV Research and Treatment #Histone Acetyltransferases #Histone #Biology #Nucleosome #Histone code #Histone deacetylase #Histone H2A #Acetylation #Chromatin #Histone deacetylase 2 #Histone methyltransferase #Genetics #Computational biology #Cell biology #Gene
29. The protein arginine deiminases: Structure, function, inhibition, and disease
    2012/07/19 by Kevin L. Bicker, Paul R. Thompson · 25 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Amino acid #Arginine #Biochemistry #Biology #Cell biology #Chemistry #Chromatin #Citrullination #Citrulline #Histone #Immunology #Inflammation #Medicine #Neutrophil extracellular traps #Peptidase Inhibition and Analysis #Protease and Inhibitor Mechanisms #Protein folding #Signaling Pathways in Disease
30. Proximity of H2A.Z containing nucleosome to the transcription start site influences gene expression levels in the mammalian liver and brain
    2012/07/19 by Rhishikesh Bargaje, Mohammad P. Alam, Ashok Patowary +10 · 1 citation
    Biochemistry, Genetics and Molecular Biology · #Biology #Chromatin #Gene #Gene expression #Genetics #Genomics and Chromatin Dynamics #Histone #Molecular biology #Nucleosome #RNA Research and Splicing #RNA modifications and cancer #Transcription (linguistics)

more