1. Shrinking to bird size with dinosaur-level cancer defences: Evolution of cancer suppression over macroevolutionary time
   2025/09/09 by E. Yagmur Erten, Marc Tollis, Hanna Kokko · 1 voice · 1 citation
   Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · #Animal Behavior and Reproduction #Cancer #Cancer cell #Cancer prevention #Evolution and Genetic Dynamics #Genetic diversity and population structure #Mutation #Mutation Accumulation #Mutation rate #Natural selection #Population #Selection (genetic algorithm)
2. Allometric scaling of somatic mutation and epimutation rates in trees
   2024/10/21 by Frank Johannes · 9 citations
   Biochemistry, Genetics and Molecular Biology · Environmental Science · #Allometry #Biology #Ecology #Evolution and Genetic Dynamics #Evolutionary biology #Gene #Genetic diversity and population structure #Genetics #Mutation #Mutation Accumulation #Mutation rate #Scaling #Somatic cell #Species Distribution and Climate Change
3. What IsNe, Anyway?
   2022/05/03 by Robin S Waples, Robin S. Waples · 38 citations
   Biochemistry, Genetics and Molecular Biology · #Allele #Biology #Computer science #Demography #Effective population size #Evolution and Genetic Dynamics #Evolutionary biology #Gene #Genetic Mapping and Diversity in Plants and Animals #Genetic diversity #Genetic diversity and population structure #Genetic drift #Genetic variation #Genetics #Inbreeding #Loss of heterozygosity #Mutation rate #Natural selection #Neutral theory of molecular evolution #Population #Population bottleneck #Population size #Selection (genetic algorithm)
4. Correlation Analysis Reveals an Important Role of GC Content in Accumulation of Deletion Mutations in the Coding Region of Angiosperm Plastomes
   2021/01/12 by Ying Yu, Hongtao Li, Hong-Tao Li +4 · 7 citations
   Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · #Biology #Chloroplast #Evolutionary biology #GC-content #Gene #Genetics #Genome #Genomics and Phylogenetic Studies #Mutation rate #Negative selection #Phylogenetic tree #Phylogenetics #Plant Diversity and Evolution #Plant and Fungal Species Descriptions #Plastid
5. What is mutation? A chapter in the series: How microbes “jeopardize” the modern synthesis
   2019/04/01 by Devon M. Fitzgerald, Susan M. Rosenberg · 1 citation
   Biochemistry, Genetics and Molecular Biology · Neuroscience · #Adaptation (eye) #Biology #CRISPR and Genetic Engineering #Computational biology #Evolution and Genetic Dynamics #Gene #Genetics #Genome #Genomics and Phylogenetic Studies #Molecular evolution #Mutagenesis #Mutation #Mutation Accumulation #Mutation rate #Neuroscience
6. Somatic POLE exonuclease domain mutations are early events in sporadic endometrial and colorectal carcinogenesis, determining driver mutational landscape, clonal neoantigen burden and immune response
   2018/03/31 by Daniel Temko, Inge C Van Gool, Inge C. van Gool +30 · 26 citations
   Biochemistry, Genetics and Molecular Biology · Medicine · #Allele #Biology #Cancer #Cancer Genomics and Diagnostics #Cancer research #Carcinogenesis #Colorectal cancer #DNA #DNA damage #DNA mismatch repair #Exome #Exome sequencing #Exonuclease #Gene #Genetic factors in colorectal cancer #Genetics #Genome instability #Germline mutation #Microsatellite #Microsatellite instability #Monoclonal and Polyclonal Antibodies Research #Mutation #Mutation rate #Somatic cell
7. Direct estimate of the spontaneous germ line mutation rate in African green monkeys
   2017/10/25 by Susanne P. Pfeifer · 28 citations
   Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · #Biology #Chromosomal and Genetic Variations #Demography #Ecology #Effective population size #Evolution and Genetic Dynamics #Evolutionary biology #Gene #Genetic diversity and population structure #Genetic variation #Genetics #Mutation #Mutation rate #Pedigree chart #Point mutation #Population #Primate
8. Evolutionary Trajectories to Antibiotic Resistance
   2017/07/12 by Diarmaid Hughes, Dan I. Andersson · 1 citation
   Biochemistry, Genetics and Molecular Biology · Medicine · Pharmacology, Toxicology and Pharmaceutics · #Antibiotic Resistance in Bacteria #Antibiotic resistance #Antibiotics #Biology #Computational biology #Drug resistance #Ecology #Epistasis #Evolution and Genetic Dynamics #Experimental evolution #Function (biology) #Gene #Genetics #Mechanism (biology) #Medicine #Mutation #Mutation rate #Pharmacogenetics and Drug Metabolism #Population #Resistance (ecology)
9. Horizontal Transfer Can Drive a Greater Transposable Element Load in Large Populations
   2016/08/24 by Sam B. Groth, Justin P. Blumenstiel · 7 citations
   Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · #Biology #CRISPR and Genetic Engineering #Chromatin #Chromosomal and Genetic Variations #Ectopic recombination #Euchromatin #Evolutionary biology #Gene #Genetic recombination #Genetics #Genome #Genome evolution #Heterochromatin #Mutation rate #Plant Disease Resistance and Genetics #Population #Recombination #Transposable element
10. Regional Differences in the Accumulation of SNPs on the Male-Specific Portion of the Human Y Chromosome Replicate Autosomal Patterns: Implications for Genetic Dating
    2015/07/30 by Beniamino Trombetta, Eugenia D’Atanasio, Andrea Massaia +4 · 1 citation
    Biochemistry, Genetics and Molecular Biology · Agricultural and Biological Sciences · #Genetic diversity and population structure #Chromosomal and Genetic Variations #Forensic and Genetic Research #Autosome #Biology #Genetics #Y chromosome #Haplogroup #Evolutionary biology #Mutation rate #Chromosome #Human genome #Haplotype #Gene #Genome #Allele
11. Elevated germline mutation rate in teenage fathers
    2015/02/18 by Peter Forster, Carsten Hohoff, Bettina Dunkelmann +4 · 1 citation
    Biochemistry, Genetics and Molecular Biology · #Cancer Genomics and Diagnostics #Evolution and Genetic Dynamics #CRISPR and Genetic Engineering #Germline #Germline mutation #Biology #Mutation rate #Sperm #Genetics #Mutation #Point mutation #Microsatellite #Germ cell #Gene #Allele
12. Improved Calibration of the Human Mitochondrial Clock Using Ancient Genomes
    2014/08/05 by Adrien Rieux, Anders Eriksson, Mingkun Li +6 · 1 citation
    Biochemistry, Genetics and Molecular Biology · #Genomics and Phylogenetic Studies #Forensic and Genetic Research #Genetic diversity and population structure #Biology #Phylogenetic tree #Molecular clock #Mitochondrial DNA #Divergence (linguistics) #Ancient DNA #Evolutionary biology #Tree (set theory) #Phylogenetics #Sequence (biology) #Calibration #Set (abstract data type) #Genome #Tree of life (biology) #Mutation rate #Data set #Genetics #Statistics #Gene #Demography #Computer science
13. Epidemiological Feedbacks Affect Evolutionary Emergence of Pathogens
    2014/02/12 by Matthew Hartfield, Samuel Alizon · 13 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Basic reproduction number #Biology #Demography #Ecology #Evolution and Genetic Dynamics #Evolutionary biology #Gene #Genetics #Mathematical and Theoretical Epidemiology and Ecology Models #Mosquito-borne diseases and control #Mutation #Mutation rate #Outbreak #Pathogen #Population #Strain (injury) #Susceptible individual #Virology
14. Are there species smaller than 1 mm?
    2013/07/24 by Axel G. Rossberg, Tim Rogers, Alan J. McKane · 9 citations
    Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · Environmental Science · Mathematics · #Abundance (ecology) #Adaptability #Biodiversity #Biology #Ecology #Evolution and Genetic Dynamics #Evolutionary biology #Genetics #Identification (biology) #Mathematics #Meiobenthos #Mutation rate #Plant and animal studies #Population #Product (mathematics) #Sociology #Species Distribution and Climate Change
15. Somatic deleterious mutation rate in a woody plant: estimation from phenotypic data
    2013/06/19 by Kyle Bobiwash, K Bobiwash, S T Schultz +3 · 13 citations
    Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · #Biology #Botany #Demography #Evolution and Genetic Dynamics #Gene #Genetic diversity and population structure #Genetics #Germline mutation #Horticulture #Inbreeding #Inbreeding depression #Inflorescence #Mutation #Mutation rate #Plant and animal studies #Pollen #Pollen source #Pollination #Pollinator #Population #Somatic cell
16. Historical variations in mutation rate in an epidemic pathogen, Yersinia pestis
    2012/12/27 by Yujun Cui, Chang Yu, Yanfeng Yan +30 · 1 citation
    Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · #Yersinia bacterium, plague, ectoparasites research #Vector-borne infectious diseases #Evolution and Genetic Dynamics #Yersinia pestis #Biology #Genetics #Nonsynonymous substitution #Single-nucleotide polymorphism #Mutation rate #Genetic drift #Natural selection #Fixation (population genetics) #Evolutionary biology #Rate of evolution #Nucleotide diversity #Genetic diversity #Genome #Gene #Haplotype #Selection (genetic algorithm) #Genetic variation #Phylogenetic tree #Allele #Genotype #Virulence #Population
17. Viral Mutation Rates
    2010/07/21 by Rafael Sanjuán, Miguel Nebot, Nicola Chirico +2 · 1 citation
    Biochemistry, Genetics and Molecular Biology · Agricultural and Biological Sciences · #Evolution and Genetic Dynamics #Plant Virus Research Studies #CRISPR and Genetic Engineering #Biology #Mutation rate #Mutation #Indel #Genetics #Viral evolution #RNA #DNA #Genome #Virology #Virus #Gene #Single-nucleotide polymorphism #Genotype
18. DNA Slippage Occurs at Microsatellite Loci without Minimal Threshold Length in Humans: A Comparative Genomic Approach
    2010/05/19 by S. Leclercq, Éric Rivals, Philippe Jarne · 2 citations
    Biochemistry, Genetics and Molecular Biology · Agricultural and Biological Sciences · #RNA and protein synthesis mechanisms #RNA Research and Splicing #Chromosomal and Genetic Variations #Indel #Microsatellite #Genetics #Tandem repeat #Biology #Mutation rate #Slippage #Genome #INDEL Mutation #Point mutation #Mutation #Single-nucleotide polymorphism #Gene
19. Explaining the Imperfection of the Molecular Clock of Hominid Mitochondria
    2009/12/28 by Eva-Liis Loogväli, Toomas Kivisild, Tõnu Margus +1 · 2 citations
    Biochemistry, Genetics and Molecular Biology · #Forensic and Genetic Research #Genomics and Phylogenetic Studies #Genetic diversity and population structure #Molecular clock #Mitochondrial DNA #Biology #Mutation rate #Negative selection #Genetics #Synonymous substitution #Phylogenetic tree #Neutral theory of molecular evolution #Evolutionary biology #Mutation #Coding region #Molecular evolution #Effective population size #Population #Mutation Accumulation #Point mutation #Heteroplasmy #Gene #Genome #Genetic variation #Codon usage bias
20. Climbing Mount Probable: Mutation as a Cause of Nonrandomness in Evolution
    2009/07/22 by Arlin Stoltzfus, Lev Y. Yampolsky · 1 citation
    Biochemistry, Genetics and Molecular Biology · #Evolution and Genetic Dynamics #Genomics and Phylogenetic Studies #Genetic diversity and population structure #Biology #Mutation #Variation (astronomy) #Evolutionary biology #Genetics #Mutation rate #Causation #Neutrality #Variance (accounting) #Human evolution #Gene #Epistemology
21. Correcting for Purifying Selection: An Improved Human Mitochondrial Molecular Clock
    2009/06/01 by Pedro Soares, Luca Ermini, Noel Thomson +8 · 144 citations
    Biochemistry, Genetics and Molecular Biology · #Biological dispersal #Biology #Demography #Evolutionary biology #Forensic and Genetic Research #Gene #Genetic diversity and population structure #Genetics #Genome #Genomics and Phylogenetic Studies #Genotype #Haplotype #Mitochondrial DNA #Molecular clock #Mutation rate #Phylogenetic tree #Population #mtDNA control region
22. Mutationism and the dual causation of evolutionary change
    2006/05/01 by Arlin Stoltzfus · 1 citation
    Biochemistry, Genetics and Molecular Biology · Social Sciences · Arts and Humanities · Psychology · #Evolution and Genetic Dynamics #Evolutionary Game Theory and Cooperation #Philosophy and History of Science #Modern evolutionary synthesis #Evolvability #Causation #Variation (astronomy) #Phenomenon #Evolutionary developmental biology #Biology #Mutation #Inheritance (genetic algorithm) #Evolutionary biology #Darwin (ADL) #Dual (grammatical number) #Epistemology #Orthodoxy #Mutation rate #Cognitive science #Genetics #Philosophy #Gene #Computer science #Psychology
23. Quantifying the genomic decay paradox due to Muller's ratchet in human mitochondrial DNA
    2006/04/01 by Laurence Loewe · 1 citation
    Biochemistry, Genetics and Molecular Biology · #Biology #DNA Repair Mechanisms #Evolution and Genetic Dynamics #Evolutionary biology #Extinction (optical mineralogy) #Gene #Genetics #Mitochondrial DNA #Mitochondrial Function and Pathology #Mutation #Mutation Accumulation #Mutation rate #Physics #Quantum mechanics #Range (aeronautics) #Ratchet #Work (physics)
24. High mutation rates have driven extensive structural polymorphism among human Y chromosomes
    2006/02/26 by Sjoerd Repping, Saskia K M van Daalen, Saskia K.M. van Daalen +13 · 1 citation
    Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · #Biology #Chromosomal and Genetic Variations #Chromosome #Copy-number variation #Evolutionary biology #Gene #Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities #Genetics #Genome #Genomics and Chromatin Dynamics #Human genome #Mutation rate #Structural variation
25. Molecular clocks: when timesare a-changin'
    2005/12/15 by S HO, Göran Larson, Башлаева Ирина Александровна +1 · 11 citations
    Biochemistry, Genetics and Molecular Biology · Computer Science · Mathematics · #Algorithm #Biology #Combinatorics #Computer science #Cybersecurity and Information Systems #Discrete mathematics #Divergence (linguistics) #Evolutionary biology #Exponential function #Extrapolation #Forensic and Genetic Research #Function (biology) #Genetic diversity and population structure #Genetics #Genomics and Phylogenetic Studies #Mathematical optimization #Mathematics #Molecular clock #Molecular evolution #Mutation #Mutation Accumulation #Mutation rate #Phylogenetics #Statistics #Term (time)
26. The Role of Selection in the Evolution of Human Mitochondrial Genomes
    2005/09/20 by Toomas Kivisild, Peidong Shen, Dennis P. Wall +14 · 19 citations
    Biochemistry, Genetics and Molecular Biology · #Genomics and Phylogenetic Studies #Forensic and Genetic Research #Genetic diversity and population structure #Nonsynonymous substitution #Biology #Mitochondrial DNA #Genetics #Mutation rate #Human mitochondrial DNA haplogroup #Synonymous substitution #Phylogenetic tree #Haplogroup #Negative selection #Mutation #Coalescent theory #Gene #Genome #Codon usage bias #Evolutionary biology #Allele #Haplotype
27. Time Dependency of Molecular Rate Estimates and Systematic Overestimation of Recent Divergence Times
    2005/04/06 by Simon Y. W. Ho, Matthew J. Phillips, Alan Cooper +1 · 14 citations
    Biochemistry, Genetics and Molecular Biology · Earth and Planetary Sciences · #Biology #Coding region #Effective population size #Evolution and Paleontology Studies #Evolutionary biology #Gene #Genetic diversity and population structure #Genetic variation #Genetics #Genomics and Phylogenetic Studies #Molecular clock #Mutation rate #Phylogenetic tree #Phylogenetics #Population #Spurious relationship #Statistics
28. Mitochondrial genome variation and the origin of modern humans
    2000/12/07 by Max Ingman, Henrik Kaessmann, Svante Pääbo +1 · 72 citations
    Biochemistry, Genetics and Molecular Biology · #Allele #Biology #Evolutionary biology #Forensic and Genetic Research #Gene #Genetic diversity and population structure #Genetics #Genome #Genomics and Phylogenetic Studies #Haplotype #Human evolution #Human genetic variation #Human genome #Human mitochondrial genetics #Mitochondrial DNA #Molecular clock #Molecular evolution #Mutation rate #Non-Mendelian inheritance #Phylogenetic tree #mtDNA control region
29. The Mutation Rate in the Human mtDNA Control Region
    2000/05/01 by Sigrún Sigurðardóttir, Agnar Helgason, Jeffrey R. Gulcher +2 · 6 citations
    Biochemistry, Genetics and Molecular Biology · #Biology #Demography #Forensic and Genetic Research #Founder effect #Gene #Genetics #Genomics and Rare Diseases #Genotype #Haplotype #Heteroplasmy #Hypervariable region #Icelandic #Metabolism and Genetic Disorders #Mitochondrial DNA #Mutation #Mutation rate #Pedigree chart #Population #mtDNA control region
30. Population growth of human Y chromosomes: a study of Y chromosome microsatellites
    1999/12/01 by Jonathan K. Pritchard, Mark Seielstad, Anna Pérez-Lezaun +1 · 14 citations
    Biochemistry, Genetics and Molecular Biology · #Genetic diversity and population structure #Genetic Associations and Epidemiology #Evolution and Genetic Dynamics #Biology #Population #Demographic history #Y chromosome #Chromosome #Microsatellite #Most recent common ancestor #Evolutionary biology #Effective population size #Genetics #Ancestor #Mutation #Mutation Accumulation #Population size #Mutation rate #Natural selection #Genetic variation #Allele #Demography #Gene #Genome

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