1. Compressive stress–driven Piezo1 activation and Rho-ROCK mechanotransduction promote tumor progression via epigenetic mechanical memory
   2026/03/04 by Sarah T. Boyle, David Gallego-Ortega, Edward J. Buckley +6 · 2 voices · 1 citation
   Biochemistry, Genetics and Molecular Biology · Medicine · #Acetylation #Cancer Cells and Metastasis #Cellular Mechanics and Interactions #Epigenetics #Erythrocyte Function and Pathophysiology #Gene silencing #Histone #Intracellular #Mechanotransduction #PIEZO1 #Tumor progression
2. Acetylation of H3K115 is associated with fragile nucleosomes at CpG island promoters and active regulatory sites
   2026/02/17 by Yatendra Kumar, Dipta Sengupta, Elias T. Friman +7 · 1 voice · 1 citation
   Biochemistry, Genetics and Molecular Biology · #Acetylation #Chromatin #CpG site #Epigenetics and DNA Methylation #Genetics and Neurodevelopmental Disorders #Genomics and Chromatin Dynamics #Histone #Histone H3 #Histone code #Nucleosome #Promoter
3. Cryo-EM reveals open and closed Asgard chromatin assemblies
   2025/10/28 by Harsh Ranawat, Marc K M Cajili, Natalia Lopez‐Barbosa +3 · 1 voice · 5 citations
   Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · #Acetylation #Advanced Electron Microscopy Techniques and Applications #ChIA-PET #Chromatin #Chromatin remodeling #Chromosomal and Genetic Variations #Genomics and Chromatin Dynamics #Histone
4. A direct interaction between the Chd1 CHCT domain and Rtf1 controls Chd1 distribution and nucleosome positioning on active genes
   2025/08/06 by Sarah A. Tripplehorn, Santana M. Lardo, Margaret K. Shirra +3 · 1 voice · 5 citations
   Biochemistry, Genetics and Molecular Biology · #Biology #Cell biology #DNA Repair Mechanisms #Domain (mathematical analysis) #Gene #Genetics #Genomics and Chromatin Dynamics #Histone #Nucleosome #RNA modifications and cancer
5. Histone lactylation-driven feedback loop modulates cholesterol-linked immunosuppression in pancreatic cancer
   2025/06/04 by Jing Yang, Xiaoning Yu, Mingming Xiao +9 · 27 citations
   Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · #Biochemistry #Biology #Cancer #Cancer research #Cancer, Lipids, and Metabolism #Cell #Epigenetics #Histone #Histone Deacetylase Inhibitors Research #Immune cells in cancer #Immune system #Immunology #Pancreatic cancer #Reprogramming #Tumor microenvironment
6. Histone modification: Biomarkers and potential therapies in colorectal cancer
   2023/09/15 by Xin An, Xiao-Hua Lan, Xiaohua Lan +3 · 10 citations
   Biochemistry, Genetics and Molecular Biology · Medicine · #Acetylation #Bioinformatics #Biology #Cancer #Cancer epigenetics #Cancer research #Colorectal cancer #Epigenetics #Epigenetics and DNA Methylation #Gene #Genetics #Histone #Histone Deacetylase Inhibitors Research #Histone methyltransferase #Medicine #Mouse model of colorectal and intestinal cancer #RNA modifications and cancer
7. Cancer epigenetics in clinical practice
   2022/12/13 by Veronica Davalos, Verónica Dávalos, Manel Esteller · 32 citations
   Biochemistry, Genetics and Molecular Biology · #Bioinformatics #Biology #Cancer #Cancer epigenetics #Cancer-related gene regulation #Carcinogenesis #Computational biology #DNA methylation #Epigenetics #Epigenetics and DNA Methylation #Gene #Gene expression #Genetics #Histone #Histone Deacetylase Inhibitors Research #Histone methyltransferase
8. Histone Acetyltransferases p300 and CBP Coordinate Distinct Chromatin Remodeling Programs in Vascular Smooth Muscle Plasticity
   2022/06/06 by Raja Chakraborty, Allison C. Ostriker, Yi Xie +14 · 27 citations
   Biochemistry, Genetics and Molecular Biology · Medicine · #Acetylation #Biology #Cancer research #Cell biology #Chromatin #Chromatin immunoprecipitation #Chromatin remodeling #Endocrinology #Epigenetics #Epigenetics and DNA Methylation #Gene #Gene expression #Gene knockdown #Genetics #Histone #Histone Acetyltransferases #Histone H4 #Internal medicine #Kruppel-like factors research #Medicine #Molecular biology #Neointima #P300-CBP Transcription Factors #Promoter #Protein Degradation and Inhibitors #Vascular smooth muscle
9. Comprehensive Analysis of Lysine Lactylation in Rice (Oryza sativa) Grains
   2021/07/15 by Xiaoxi Meng, Jonathan M. Baine, Tingcai Yan +1 · 26 citations
   Biochemistry, Genetics and Molecular Biology · Materials Science · #Amino acid #Biochemistry #Biology #Botany #Enzyme Structure and Function #Fungal and yeast genetics research #Gene #Histone #Lysine #Oryza sativa #Ubiquitin and proteasome pathways
10. Histone variants at a glance
    2021/03/15 by Paul B. Talbert, Steven Henikoff · 29 citations
    Biochemistry, Genetics and Molecular Biology · #Biology #Computational biology #DNA #Epigenetics and DNA Methylation #Evolutionary biology #Genetics #Genomics and Chromatin Dynamics #Histone #RNA modifications and cancer
11. Biophysics of Chromatin Remodeling
    2021/01/05 by Ilana M. Nodelman, Gregory D. Bowman · 1 citation
    Biochemistry, Genetics and Molecular Biology · #Biology #Cell biology #Chromatin #Chromatin Remodeling and Cancer #Chromatin remodeling #Computational biology #DNA #Epigenetics #Epigenetics and DNA Methylation #Gene #Genetics #Genomics and Chromatin Dynamics #Helicase #Histone #Nucleosome #RNA
12. Telomeres and telomerase in risk assessment of cardiovascular diseases
    2020/11/07 by Ewa Boniewska‐Bernacka, Ewa Boniewska-Bernacka, Anna Pańczyszyn +1 · 16 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Biology #Cancer research #Cell biology #DNA #DNA damage #Gene #Genetics #Genetics, Aging, and Longevity in Model Organisms #Histone #Immunology #Inflammation #Phenotype #Senescence #Telomerase #Telomere #Telomeres, Telomerase, and Senescence
13. Palmitate‐TLR4 signaling regulates the histone demethylase, JMJD3, in macrophages and impairs diabetic wound healing
    2020/07/14 by Frank M. Davis, Aaron D. denDekker, Aaron denDekker +12 · 26 citations
    Immunology and Microbiology · Medicine · #Biochemistry #Biology #Cancer research #Cell biology #Demethylase #Downregulation and upregulation #Gene #Histone #Immune Response and Inflammation #Immune cells in cancer #Immunology #Inflammation #Macrophage #Monocyte #TLR4 #Wound Healing and Treatments
14. H3.3 K27M depletion increases differentiation and extends latency of diffuse intrinsic pontine glioma growth in vivo
    2019/02/15 by André B. Silveira, André Bortolini Silveira, Lawryn H. Kasper +27 · 25 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Biology #Cancer research #Cancer-related molecular mechanisms research #Chromatin Remodeling and Cancer #DNA methylation #Epigenetics #Epigenome #Gene #Gene expression #Gene knockdown #Genetics #Glioma #Glioma Diagnosis and Treatment #Histone #Histone H3 #Mutation #Phenotype #Transcriptome
15. Histones predate the split between bacteria and archaea
    2018/12/05 by Vikram Alva, Andrei N. Lupas · 1 citation
    Biochemistry, Genetics and Molecular Biology · #Bacterial Genetics and Biotechnology #Genomics and Chromatin Dynamics #Protist diversity and phylogeny #Histone #Biology #Archaea #Nucleosome #Histone-modifying enzymes #Genetics #Histone code #Chromatin #DNA #Evolutionary biology #Computational biology #Gene
16. KDM5 demethylases and their role in cancer cell chemoresistance
    2018/09/24 by Johana Plch, Jan Hraběta, Jan Hrabeta +2 · 26 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Biology #Cancer #Cancer epigenetics #Cancer research #Cancer-related gene regulation #DNA methylation #Downregulation and upregulation #Epigenetics #Epigenetics and DNA Methylation #Gene #Gene expression #Genetics #Histone #Histone Deacetylase Inhibitors Research #Histone methylation #Histone methyltransferase #Medicine #Methylation #Population #Suppressor
17. Site-Specific Disulfide Crosslinked Nucleosomes with Enhanced Stability
    2017/11/04 by T.D. Frouws, Philip Barth, Timothy J. Richmond · 1 citation
    Biochemistry, Genetics and Molecular Biology · Chemistry · #Advanced biosensing and bioanalysis techniques #Biochemistry #Biology #Biophysics #Chemistry #Crystallization #Crystallography #Cysteine #DNA #Dimer #Dissociation (chemistry) #Enzyme #Genomics and Chromatin Dynamics #Histone #Histone octamer #Linker DNA #Mutant #Nucleosome #Organic chemistry #Point mutation #RNA Interference and Gene Delivery
18. Nucleosomes Selectively Inhibit Cas9 Off-target Activity at a Site Located at the Nucleosome Edge
    2016/10/19 by John M. Hinz, Marian F. Laughery, John J. Wyrick · 12 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · #Advanced biosensing and bioanalysis techniques #Biology #Biophysics #CRISPR #CRISPR and Genetic Engineering #Cas9 #Cell biology #Chemistry #Cleavage (geology) #DNA #Gene #Genetics #Histone #Nucleosome #RNA Interference and Gene Delivery
19. Past, present, and future of epigenetics applied to livestock breeding
    2015/09/28 by Óscar González-Recio, M. Á. Toro, À. Bach · 1 citation
    Biochemistry, Genetics and Molecular Biology · Medicine · #Epigenetics and DNA Methylation #Birth, Development, and Health #Animal Genetics and Reproduction #Epigenetics #Biology #DNA methylation #Genetics #Inheritance (genetic algorithm) #Epigenesis #Histone #Gene #Phenotype #Evolutionary biology #Epigenomics #Genome #Computational biology #Gene expression
20. Histone H3F3A and HIST1H3B K27M mutations define two subgroups of diffuse intrinsic pontine gliomas with different prognosis and phenotypes
    2015/09/23 by David Castel, Cathy Philippe, Raphaël Calmon +18 · 27 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Biology #Cancer research #Cancer-related molecular mechanisms research #Gene #Gene expression #Gene expression profiling #Genetics #Glioma #Glioma Diagnosis and Treatment #Histone #Histone H3 #Medicine #Mutation #Pathology #Phenotype #RNA modifications and cancer
21. Extracellular Histones Play an Inflammatory Role in Acid Aspiration-induced Acute Respiratory Distress Syndrome
    2014/09/05 by Yanlin Zhang, Zongmei Wen, Li Guan +5 · 25 citations
    Immunology and Microbiology · Medicine · #ARDS #Biochemistry #Biology #Cell biology #Extracellular #Histone #Immune cells in cancer #Immunology #Inflammation #Internal medicine #Lung #Medicine #Neutrophil extracellular traps #Neutrophil, Myeloperoxidase and Oxidative Mechanisms #Pathogenesis #Respiratory Support and Mechanisms
22. Omics Tools for the Genome-Wide Analysis of Methylation and Histone Modifications
    2014/01/01 by Josep C. Jiménez-Chillarón, Rubén Díaz, Marta Ramón-Krauel +1 · 1 citation
    Biochemistry, Genetics and Molecular Biology · #Biology #Cancer-related gene regulation #Computational biology #DNA methylation #Epigenetics #Epigenetics and DNA Methylation #Epigenomics #Gene #Gene expression #Genetics #Genome #Genomics #Histone #Proteomics #RNA modifications and cancer
23. Reduced C9orf72 gene expression in c9FTD/ALS is caused by histone trimethylation, an epigenetic event detectable in blood
    2013/10/28 by Veronique V. Belzil, Véronique Belzil, Peter Bauer +18 · 26 citations
    Medicine · #Allele #Amyotrophic Lateral Sclerosis Research #Biology #C9orf72 #Chromatin #Chromatin immunoprecipitation #Epigenetics #Gene #Gene expression #Genetics #Haploinsufficiency #Histone #Histone H3 #Molecular biology #Neurogenetic and Muscular Disorders Research #Parkinson's Disease Mechanisms and Treatments #Phenotype #Promoter #Regulation of gene expression #Trinucleotide repeat expansion
24. Serum-mediated transgenerational effects on sperm: Evidence for lamarckian inheritance?
    2013/04/01 by Yoshiyuki Seki, Roberto J. Groszmann, Yasuko Iwakiri +1 · 1 citation
    Biochemistry, Genetics and Molecular Biology · Medicine · #Epigenetics and DNA Methylation #Hemoglobinopathies and Related Disorders #Biology #Epigenetics #DNA methylation #Myofibroblast #Reprogramming #Histone #Chromatin remodeling #Fibrosis #Cancer research #Chromatin #Epigenome #Cell biology #Sperm #Endocrinology #Internal medicine #Genetics #Gene expression #Medicine #Gene
25. Edible blue-green algae reduce the production of pro-inflammatory cytokines by inhibiting NF-κB pathway in macrophages and splenocytes
    2013/01/26 by Chai Siah Ku, Tho X. Pham, Young‐Ki Park +6 · 1 citation
    Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · Energy · #Algal biology and biofuel production #Biochemistry #Biology #Cytokine #Endocrinology #Histone #Histone deacetylase #Immunology #Inflammation #Lipopolysaccharide #Microbial metabolism and enzyme function #Molecular biology #Proinflammatory cytokine #Seaweed-derived Bioactive Compounds #Tumor necrosis factor alpha
26. Expression of Sox4 and Sox11 is regulated by multiple mechanisms during retinal development
    2013/01/08 by Ayumi Usui, Toshiro Iwagawa, Yujin Mochizuki +4 · 12 citations
    Biochemistry, Genetics and Molecular Biology · #Acetylation #Biochemistry #Biology #Cell biology #Congenital heart defects research #Developmental Biology and Gene Regulation #Epigenetics #Epigenetics and DNA Methylation #Gene #Gene expression #Genetics #Histone #Histone H3 #Locus (genetics) #Retinal #SOX4
27. The histone deacetylase inhibitor trichostatin A reduces lysosomal pH and enhances cisplatin-induced apoptosis
    2012/10/17 by I. Eriksson, Ida Eriksson, Maria Joosten +5 · 18 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Apoptosis #Autophagy in Disease and Therapy #Biochemistry #Biology #Cathepsin #Cathepsin B #Cathepsin D #Cathepsin L #Cell biology #Enzyme #Histone #Histone Deacetylase Inhibitors Research #Histone deacetylase #Histone deacetylase inhibitor #Lysosomal Storage Disorders Research #Molecular biology #Programmed cell death #Trichostatin A
28. Toxoplasmahistone acetylation remodelers as novel drug targets
    2012/10/01 by Laura Vanagas, Victoria Jeffers, Silvina S. Bogado +3 · 1 citation
    Immunology and Microbiology · Medicine · #Toxoplasma gondii Research Studies #Herpesvirus Infections and Treatments #HIV Research and Treatment #Histone Acetyltransferases #Histone #Biology #Nucleosome #Histone code #Histone deacetylase #Histone H2A #Acetylation #Chromatin #Histone deacetylase 2 #Histone methyltransferase #Genetics #Computational biology #Cell biology #Gene
29. The protein arginine deiminases: Structure, function, inhibition, and disease
    2012/07/19 by Kevin L. Bicker, Paul R. Thompson · 25 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Amino acid #Arginine #Biochemistry #Biology #Cell biology #Chemistry #Chromatin #Citrullination #Citrulline #Histone #Immunology #Inflammation #Medicine #Neutrophil extracellular traps #Peptidase Inhibition and Analysis #Protease and Inhibitor Mechanisms #Protein folding #Signaling Pathways in Disease
30. Proximity of H2A.Z containing nucleosome to the transcription start site influences gene expression levels in the mammalian liver and brain
    2012/07/19 by Rhishikesh Bargaje, Mohammad P. Alam, Ashok Patowary +10 · 1 citation
    Biochemistry, Genetics and Molecular Biology · #Biology #Chromatin #Gene #Gene expression #Genetics #Genomics and Chromatin Dynamics #Histone #Molecular biology #Nucleosome #RNA Research and Splicing #RNA modifications and cancer #Transcription (linguistics)

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