1. SARS-CoV-2 induces Alzheimer’s disease–related amyloid-β pathology in ex vivo human retinal explants and retinal organoids
   2025/07/04 by Sean Miller, Rahul M. Dhodapkar, Hande Eda Sutova +14 · 2 voices · 2 citations
   Medicine · Neuroscience · #Alzheimer's disease #Amyloid (mycology) #Amyloid precursor protein #Biochemistry #Biology #Disease #Ex vivo #Immunology #In vivo #Long-Term Effects of COVID-19 #Medicine #Neuroscience #Organoid #Pathology #Retinal #Retinal Imaging and Analysis #Retinal and Optic Conditions
2. Lack of ceramide synthase 5 protects retinal ganglion cells from ocular hypertensive injury
   2024/08/27 by Jian Liu, Yiannis Koutalos, Jie Fan · 1 citation
   Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · Neuroscience · #Apoptosis #Biochemistry #Biology #Cell #Cell biology #Ceramide #Ceramide synthase #Chemistry #Enzyme #Glaucoma #Glaucoma and retinal disorders #Lipid signaling #Neuroscience #Ocular hypertension #Retinal #Retinal ganglion cell #Sleep and Wakefulness Research #Sphingolipid Metabolism and Signaling #Viability assay
3. Comprehensive mass spectrometry lipidomics of human biofluids and ocular tissues
   2023/02/10 by Glenda Vasku, Caroline Peltier, Zhiguo Hé +7 · 8 citations
   Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Biochemistry #Chemistry #Cholesterol #Cholesterol and Lipid Metabolism #Chromatography #High-performance liquid chromatography #Hydrophilic interaction chromatography #Lipid metabolism #Lipidome #Lipidomics #Macular degeneration #Mass spectrometry #Medicine #Metabolome #Metabolomics #Metabolomics and Mass Spectrometry Studies #Retinal #Retinal Diseases and Treatments #Retinal pigment epithelium
4. Recovery of dopaminergic amacrine cells after strobe light stimulation in the developing rat retina
   2023/02/11 by Soo‐Jin Song, Soo-Jin Song, Eun-Jin Lee +4 · 1 citation
   Biochemistry, Genetics and Molecular Biology · Medicine · Neuroscience · #Biology #Circadian rhythm #Circadian rhythm and melatonin #Dopamine #Dopaminergic #Endocrinology #Internal medicine #Medicine #Neuroscience #Ophthalmology #Photoreceptor and optogenetics research #Retina #Retinal #Retinal Development and Disorders #Stimulation #Tyrosine hydroxylase
5. Inherited causes of combined vision and hearing loss: clinical features and molecular genetics
   2022/09/26 by Thales Antonio Cabral de Guimaraes, Thales A. C. de Guimarães, Elizabeth Arram +4 · 7 citations
   Biochemistry, Genetics and Molecular Biology · Medicine · #Audiology #Bardet–Biedl syndrome #Biology #Ciliopathies #Congenital Ear and Nasal Anomalies #Gene #Genetic and Kidney Cyst Diseases #Genetic heterogeneity #Genetics #Hearing loss #Medicine #Mitochondrial DNA #Mitochondrial disease #Molecular genetics #Ophthalmology #Phenotype #Retinal #Retinal Development and Disorders #Retinitis pigmentosa #Usher syndrome
6. A demonstration of cone function plasticity after gene therapy in achromatopsia
   2022/08/23 by Mahtab Farahbakhsh, Elaine J. Anderson, Roni O. Maimon-Mor +9 · 1 citation
   Neuroscience · Biochemistry, Genetics and Molecular Biology · Medicine · Psychology · #Visual perception and processing mechanisms #Retinal Development and Disorders #Connexins and lens biology #Achromatopsia #Neuroscience #Visual acuity #Population #Medicine #Ophthalmology #Psychology #Retinal
7. Prediction of visual impairment in retinitis pigmentosa using deep learning and multimodal fundus images
   2022/07/27 by Tin Yan Alvin Liu, Carlthan Ling, Leo Hahn +7 · 10 citations
   Biochemistry, Genetics and Molecular Biology · Medicine · #Artificial intelligence #Computer science #Deep learning #Fundus (uterus) #Medicine #Ophthalmology #Ophthalmology and Visual Impairment Studies #Ophthalmoscopy #Retinal #Retinal Development and Disorders #Retinal Diseases and Treatments #Retinitis pigmentosa #Visual acuity
8. E-cadherin to N-cadherin switching in the TGF-β1 mediated retinal pigment epithelial to mesenchymal transition
   2022/04/29 by Jiayi Wei, Liangjing Wu, Shuai Yang +5 · 13 citations
   Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Biochemistry #Biology #Cadherin #Cancer research #Cancer-related Molecular Pathways #Catenin #Cell #Cell biology #Chemistry #Downregulation and upregulation #Epithelial–mesenchymal transition #Hippo pathway signaling and YAP/TAZ #Proliferative vitreoretinopathy #Retinal #Retinal detachment #Retinal pigment epithelium #Signal transduction #Transforming growth factor #Wnt signaling pathway #Wnt/β-catenin signaling in development and cancer
9. Retinal nerve fibre layer thickness measured with SD-OCT in a population-based study: the Handan Eye Study
   2022/04/05 by Jian Wu, Yifan Du, Caixia Lin +5 · 15 citations
   Medicine · #Glaucoma #Glaucoma and retinal disorders #Intraocular pressure #Medicine #Nerve fiber layer #Ophthalmology #Optical coherence tomography #Population #Quadrant (abdomen) #Retinal #Retinal Diseases and Treatments #Retinal Imaging and Analysis #Surgery
10. In vivo imaging of the inner retinal layer structure in mice after eye-opening using visible-light optical coherence tomography
    2021/09/04 by Lisa Beckmann, Zhen Cai, James Cole +9 · 11 citations
    Biochemistry, Genetics and Molecular Biology · Engineering · Medicine · #Adaptive optics #Biology #Biomedical engineering #Confocal #Confocal microscopy #Contrast (vision) #Ex vivo #Glaucoma and retinal disorders #In vivo #Materials science #Medicine #Ophthalmology #Optical Coherence Tomography Applications #Optical coherence tomography #Optics #Physics #Preclinical imaging #Retina #Retinal #Retinal Development and Disorders
11. Prediction of causative genes in inherited retinal disorder from fundus photography and autofluorescence imaging using deep learning techniques
    2021/04/20 by Yu Fujinami-Yokokawa, Yu Fujinami‐Yokokawa, Hideki Ninomiya +10 · 22 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #ABCA4 #Artificial intelligence #Biology #Computer science #Concordance #Fluorescein angiography #Fundus (uterus) #Fundus photography #Gene #Genetics #Internal medicine #Medicine #Ophthalmology #Optometry #Retinal #Retinal Development and Disorders #Retinal Diseases and Treatments #Retinal Imaging and Analysis #Retinitis pigmentosa
12. NF-κB activation in retinal microglia is involved in the inflammatory and neovascularization signaling in laser-induced choroidal neovascularization in mice
    2021/03/31 by Fumihito Hikage, Anton Lennikov, Anthony Mukwaya +7 · 20 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Angiogenesis #Biochemistry #Biology #Cancer research #Cell biology #Choroidal neovascularization #Gene #Genetics #Immunology #Inflammation #Microglia #NF-κB #NF-κB Signaling Pathways #NFKB1 #Neovascularization #Ocular Diseases and Behçet’s Syndrome #Retinal #Retinal Diseases and Treatments #Signal transduction #Transcription factor
13. Retinal microvascular abnormalities in patients after COVID-19 depending on disease severity
    2020/12/16 by Miguel Ángel Zapata, Sandra Banderas García, Adrián Sánchez-Moltalvá +9 · 27 citations
    Medicine · #Asymptomatic #Gastroenterology #Intensive care unit #Internal medicine #Medicine #Ophthalmology #Pneumonia #Retinal #Retinal Imaging and Analysis #Retinal and Optic Conditions #Retinopathy of Prematurity Studies
14. Update in the epidemiology, risk factors, screening, and treatment of diabetic retinopathy
    2020/12/15 by Kuan‐Yu Lin, Wen‐Hui Hsih, Yen‐Bo Lin +2 · 1 citation
    Medicine · #Retinal Diseases and Treatments #Retinal Imaging and Analysis #Acute Ischemic Stroke Management #Medicine #Diabetic retinopathy #Blindness #Diabetes mellitus #Fundus (uterus) #Ophthalmology #Retinopathy #Macular edema #Epidemiology #Diabetic macular edema #Optometry #Internal medicine #Retinal #Endocrinology
15. Function of mammalian M-cones depends on the level of CRALBP in Müller cells
    2020/11/20 by Alexander V. Kolesnikov, Philip D. Kiser, Krzysztof Palczewski +1 · 10 citations
    Biochemistry, Genetics and Molecular Biology · Materials Science · Neuroscience · #Adaptation (eye) #Anatomy #Biochemistry #Biology #Biophysics #Cell biology #Compound eye #Electroretinography #Muller glia #Neuroscience #Neuroscience and Neuropharmacology Research #Optics #Photochromic and Fluorescence Chemistry #Physics #Progenitor cell #Regeneration (biology) #Retina #Retinal #Retinal Development and Disorders #Retinal pigment epithelium #Retinal regeneration #Stem cell #Visual phototransduction
16. RSK3 mediates necroptosis by regulating phosphorylation of RIP3 in rat retinal ganglion cells
    2020/03/12 by Mi Wang, Hao Wan, Shuchao Wang +11 · 23 citations
    Biochemistry, Genetics and Molecular Biology · #Apoptosis #Biochemistry #Biology #Cell biology #Cell death mechanisms and regulation #Hippo pathway signaling and YAP/TAZ #Kinase #Mitochondrial Function and Pathology #Necroptosis #Phosphorylation #Programmed cell death #Regulator #Retinal #Retinal ganglion cell
17. The role of Müller cells in tractional macular disorders: an optical coherence tomography study and physical model of mechanical force transmission
    2019/07/20 by Andrea Govetto, Jean-Pierre Hubschman, Jean‐Pierre Hubschman +19 · 19 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Foveal #Medicine #Ocular Disorders and Treatments #Ophthalmology #Ophthalmology and Visual Impairment Studies #Optical coherence tomography #Optics #Physics #Retina #Retinal #Retinal and Macular Surgery #Visual acuity
18. Vision using multiple distinct rod opsins in deep-sea fishes
    2019/05/09 by Zuzana Musilová, Fabio Cortesi, Michael Matschiner +15 · 1 citation
    Biochemistry, Genetics and Molecular Biology · Environmental Science · Neuroscience · #Anatomy #Biology #Botany #Evolutionary biology #Fish <Actinopterygii> #Fishery #Gene #Genetics #Ichthyology and Marine Biology #Neuroscience #Opsin #Photopigment #Photoreceptor and optogenetics research #Retina #Retinal #Retinal Development and Disorders #Rhodopsin #Vertebrate
19. Reductions in final visual acuity occur even within the first 3 days after a macula-off retinal detachment
    2018/12/01 by Margaret A Greven, Margaret A. Greven, Theodore Leng +11 · 19 citations
    Medicine · #Corneal surgery and disorders #Medicine #Ophthalmology #Ophthalmology and Visual Impairment Studies #Retinal #Retinal and Macular Surgery #Retinal detachment #Scleral buckle #Scleral buckling #Surgery #Visual acuity #Vitrectomy
20. Neurodegeneration in diabetic retinopathy: does it really matter?
    2018/07/20 by Rafael Simó, Alan W. Stitt, Thomas W. Gardner · 29 citations
    Medicine · Neuroscience · Psychology · #Bioinformatics #Biology #Diabetes mellitus #Diabetic retinopathy #Disease #Endocrinology #Glaucoma and retinal disorders #Internal medicine #Medicine #Neurodegeneration #Neuroprotection #Neuroscience #Ophthalmology #Psychology #Retinal #Retinal Diseases and Treatments #Retinal Imaging and Analysis
21. Sheets of human retinal progenitor transplants improve vision in rats with severe retinal degeneration
    2018/05/18 by Bin Lin, Bryce T. McLelland, Anuradha Mathur +2 · 27 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · Neuroscience · #Anatomy #Biology #Medicine #Neuroscience #Ophthalmology #Retina #Retinal #Retinal Development and Disorders #Retinal Diseases and Treatments #Retinal and Optic Conditions #Retinal degeneration #Retinal pigment epithelium #Retinal regeneration #Retinitis pigmentosa #Superior colliculus #Surgery #Transplantation
22. Electroretinographic anomalies in schizophrenia.
    2018/05/01 by Docia L. Demmin, Docia Demmin, Quentin Davis +3 · 26 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · Neuroscience · Psychology · #Audiology #Cognitive psychology #Electroretinography #Medicine #Neuroscience #Neuroscience and Neuropharmacology Research #Nicotinic Acetylcholine Receptors Study #Ophthalmology #Photopic vision #Psychiatry #Psychology #Psychosis #Retina #Retinal #Retinal Development and Disorders #Schizophrenia (object-oriented programming) #Scotopic vision #Stimulus (psychology)
23. Retinal Microperimetry: A New Tool for Identifying Patients With Type 2 Diabetes at Risk for Developing Alzheimer Disease
    2017/09/26 by Andreea Ciudin, Olga Simó-Servat, Olga Simó‐Servat +9 · 23 citations
    Medicine · Neuroscience · Psychology · #Alzheimer's disease #Dementia #Dementia and Cognitive Impairment Research #Diabetes mellitus #Disease #Endocrinology #Internal medicine #Medicine #Microperimetry #Neurodegeneration #Neuroscience #Ophthalmology #Psychology #Retinal #Retinal Diseases and Treatments #Retinal Imaging and Analysis
24. Label free measurement of retinal blood cell flux, velocity, hematocrit and capillary width in the living mouse eye
    2016/09/23 by Andrés Guevara–Torres, Aby Joseph, Jesse Schallek · 1 voice · 28 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Advanced Fluorescence Microscopy Techniques #Biomedical engineering #Contrast (vision) #Glaucoma and retinal disorders #Human eye #Materials science #Medicine #Ophthalmology #Optics #Physics #Retina #Retinal #Retinal Diseases and Treatments
25. Retinal remodeling in human retinitis pigmentosa
    2016/03/26 by B.W. Jones, Bryan W. Jones, R.L. Pfeiffer +8 · 27 citations
    Biochemistry, Genetics and Molecular Biology · Neuroscience · #Biology #Cell #Cell biology #Genetics #Muller glia #Neuroscience #Neuroscience and Neural Engineering #Photoreceptor and optogenetics research #Progenitor cell #Reprogramming #Retina #Retinal #Retinal Development and Disorders #Retinal Disorder #Retinal degeneration #Retinitis pigmentosa #Stem cell
26. Spare the rods and spoil the retina: revisited
    2015/12/11 by S Sivaprasad, Sobha Sivaprasad, G Arden +1 · 1 citation
    Medicine · Neuroscience · #Adaptation (eye) #Biology #Diabetes mellitus #Diabetic retinopathy #Endocrinology #Glaucoma and retinal disorders #Maculopathy #Medicine #Neuroscience #Ophthalmology #Optometry #Retina #Retinal #Retinal Diseases and Treatments #Retinal Imaging and Analysis #Retinopathy
27. Role of epithelial–mesenchymal transition in proliferative vitreoretinopathy
    2015/12/10 by Shigeo Tamiya, Henry J. Kaplan · 25 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Adherens junction #Biology #Cadherin #Cell #Cell biology #Chemistry #Downregulation and upregulation #Epithelial–mesenchymal transition #Extracellular matrix #Fibrosis #Glaucoma and retinal disorders #Hippo pathway signaling and YAP/TAZ #Medicine #Myofibroblast #Pathology #Proliferative vitreoretinopathy #Retinal #Retinal and Macular Surgery #Retinal detachment #Retinal pigment epithelium #Signal transduction #Wnt signaling pathway
28. Using the rd1 mouse to understand functional and anatomical retinal remodelling and treatment implications in retinitis pigmentosa: A review
    2015/11/03 by Michael Kalloniatis, M. Kalloniatis, Lisa Nivison‐Smith +7 · 25 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · Neuroscience · #Biology #Gene therapy of the human retina #Macular degeneration #Medicine #Neuroscience #Neuroscience and Neuropharmacology Research #Ophthalmology #Photoreceptor and optogenetics research #Retina #Retinal #Retinal Development and Disorders #Retinal degeneration #Retinal pigment epithelium #Retinitis pigmentosa
29. Topical Administration of GLP-1 Receptor Agonists Prevents Retinal Neurodegeneration in Experimental Diabetes
    2015/09/17 by Cristina Hernández, Patricia Bogdanov, Lidia Corraliza +10 · 32 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · Neuroscience · #Adenosine and Purinergic Signaling #Agonist #Biology #Diabetes Treatment and Management #Diabetes mellitus #Diabetic retinopathy #Endocrinology #Exenatide #Internal medicine #Liraglutide #Medicine #Neurodegeneration #Neuroprotection #Neuroscience #Ophthalmology #Pharmacology #Receptor #Retina #Retinal #Retinal Diseases and Treatments #Systemic administration #Type 2 diabetes
30. Protective effects of methane-rich saline on diabetic retinopathy via anti-inflammation in a streptozotocin-induced diabetic rat model
    2015/09/11 by Jiangchun Wu, Ruobing Wang, Zhouheng Ye +5 · 25 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Advanced Glycation End Products research #Blood–retinal barrier #Diabetes mellitus #Diabetic retinopathy #Endocrinology #Evans Blue #Glial fibrillary acidic protein #Immunohistochemistry #Inflammation #Internal medicine #Medicine #Ophthalmology #Retinal #Retinal Diseases and Treatments #Retinal Imaging and Analysis #Streptozotocin #Vascular endothelial growth factor

more