- Structural basis of the mechanism and inhibition of a human ceramide synthase
2024/11/11 by Tomas C. Pascoa, A.C.W. Pike, Christofer S. Tautermann +10 · 1 voice · 12 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Materials Science · #ATP synthase #Apoptosis #Biochemistry #Biology #Carbohydrate Chemistry and Synthesis #Cell biology #Ceramide #Ceramide synthase #Chemistry #Enzyme #Mechanism (biology) #Physics #Porphyrin and Phthalocyanine Chemistry #Sphingolipid #Sphingolipid Metabolism and Signaling
- Lack of ceramide synthase 5 protects retinal ganglion cells from ocular hypertensive injury
2024/08/27 by Jian Liu, Yiannis Koutalos, Jie Fan · 1 citation
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · Neuroscience · #Apoptosis #Biochemistry #Biology #Cell #Cell biology #Ceramide #Ceramide synthase #Chemistry #Enzyme #Glaucoma #Glaucoma and retinal disorders #Lipid signaling #Neuroscience #Ocular hypertension #Retinal #Retinal ganglion cell #Sleep and Wakefulness Research #Sphingolipid Metabolism and Signaling #Viability assay
- Ceramides in Metabolism: Key Lipotoxic Players
2020/11/07 by Bhagirath Chaurasia, Scott A. Summers · 4 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Biochemistry #Bioinformatics #Biology #Cell biology #Ceramide #Diabetes mellitus #Disease #Dyslipidemia #Endocrinology #Fatty liver #Insulin resistance #Internal medicine #Lipid Membrane Structure and Behavior #Lipid metabolism #Lipotoxicity #Medicine #Peroxisome Proliferator-Activated Receptors #Sphingolipid #Sphingolipid Metabolism and Signaling #Steatohepatitis #Type 2 Diabetes Mellitus
- The Cumulus Cell Layer Protects the Bovine Maturing Oocyte Against Fatty Acid-Induced Lipotoxicity1
2014/10/09 by Francesca Lolicato, Jos F. Brouwers, Chris H.A. van de Lest +6 · 26 citations
Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · Medicine · #Adipose tissue #Apoptosis #Biochemistry #Biology #Cell biology #Ceramide #Embryo #Endocrinology #Fatty acid #Internal medicine #Lipid droplet #Lipid metabolism and biosynthesis #Lipolysis #Oocyte #Perilipin #Reproductive Biology and Fertility #Reproductive Physiology in Livestock
- Ceramide Phosphoethanolamine Biosynthesis in Drosophila Is Mediated by a Unique Ethanolamine Phosphotransferase in the Golgi Lumen
2013/03/01 by Ana M. Vacaru, Joep van den Dikkenberg, Philipp Ternes +1 · 1 citation
Biochemistry, Genetics and Molecular Biology · #Biochemistry #Biology #Biosynthesis #Cell biology #Cellular transport and secretion #Ceramide #Endoplasmic reticulum #Enzyme #Golgi apparatus #Lipid Membrane Structure and Behavior #Membrane #Phosphotransferase #Sphingolipid #Sphingolipid Metabolism and Signaling #Sphingomyelin
- Hsp70.1 and related lysosomal factors for necrotic neuronal death
2011/11/26 by Tetsumori Yamashima · 26 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · #Acid sphingomyelinase #Apoptosis #Biochemistry #Biology #Calpain #Calpain Protease Function and Regulation #Cathepsin #Cathepsin D #Cell biology #Cell death mechanisms and regulation #Ceramide #Chemistry #Enzyme #Heat shock protein #Heat shock proteins research #Hsp70 #Membrane #Oxidative stress #Programmed cell death #Reactive oxygen species #Sphingomyelin
- Secretory Mechanisms and Intercellular Transfer of MicroRNAs in Living Cells
2010/03/30 by Nobuyoshi Kosaka, Haruhisa Iguchi, Yusuke Yoshioka +3 · 38 citations
Biochemistry, Genetics and Molecular Biology · #Apoptosis #Biochemistry #Biology #Cell biology #Ceramide #Endosome #Exocytosis #Exosome #Extracellular #Extracellular vesicle #Extracellular vesicles in disease #Gene #Gene silencing #Golgi apparatus #Intracellular #MicroRNA in disease regulation #Microvesicles #RNA #RNA interference #Secretion #Secretory Vesicle #Secretory pathway #Sphingolipid Metabolism and Signaling #microRNA
- Mechanisms of sphingosine and sphingosine 1-phosphate generation in human platelets
2005/08/02 by Motohiro Tani, Takamitsu Sano, Makoto Ito +1 · 25 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Biochemistry #Biology #Cell biology #Ceramide #Chemistry #Enzyme #Erythrocyte Function and Pathophysiology #Extracellular #Immunology #Lipid signaling #Membrane #Platelet #Platelet Disorders and Treatments #Platelet activation #Receptor #Sphingolipid #Sphingolipid Metabolism and Signaling #Sphingomyelin #Sphingosine #Sphingosine kinase #Sphingosine-1-phosphate
- Nicotinamide increases biosynthesis of ceramides as well as other stratum corneum lipids to improve the epidermal permeability barrier
2000/09/01 by Osamu Tanno, Y. Ota, N Kitamura +2 · 3 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · Pharmacology, Toxicology and Pharmaceutics · #Advancements in Transdermal Drug Delivery #Barrier function #Biochemistry #Biology #Biosynthesis #Cell biology #Ceramide #Chemistry #Cholesterol #Dermatology and Skin Diseases #Enzyme #Nicotinamide #Sphingolipid #Sphingolipid Metabolism and Signaling #Sphingomyelin #Stratum corneum #Transepidermal water loss
- Sphingolipids in Food and the Emerging Importance of Sphingolipids to Nutrition
1999/07/01 by Hubert W. Vesper, Hubert Vesper, Eva-Maria Schmelz +5 · 1 citation
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Apoptosis #Biochemistry #Biology #Ceramide #Chemistry #Cholesterol #Food science #Glycolipid #Lactosylceramide #Lipid metabolism and biosynthesis #Lysosomal Storage Disorders Research #Sphingolipid #Sphingolipid Metabolism and Signaling #Sphingomyelin #Sphingosine
- Ceramide mediates tumor necrosis factor effects on P450-aromatase activity in cultured granulosa cells.
1995/05/01 by M Santana, P Santana, L Llanes +14 · 8 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Immunology and Microbiology · Medicine · #Apoptosis #Aromatase #Biochemistry #Biology #Cell biology #Ceramide #Chemistry #Cholesterol #Drug Transport and Resistance Mechanisms #Endocrinology #Internal medicine #Lipid signaling #Medicine #Phagocytosis and Immune Regulation #Phosphorylcholine #Receptor #Sphingolipid #Sphingolipid Metabolism and Signaling #Sphingomyelin #Tumor necrosis factor alpha
- Human stratum corneum lipids: characterization and regional variations
1983/02/01 by Marilyn A. Lampe, A. L. Burlingame, J. E. Whitney +4 · 1 citation
Pharmacology, Toxicology and Pharmaceutics · Biochemistry, Genetics and Molecular Biology · Chemistry · #Advancements in Transdermal Drug Delivery #Lipid Membrane Structure and Behavior #Surfactants and Colloidal Systems #Stratum corneum #Sphingolipid #Chemistry #Biochemistry #Ceramide #Squalene #Fatty acid #Corneocyte #Barrier function #Chromatography #Cholesterol #Biophysics #Biology #Cell biology
- THE HYDROGEN CONTENT AND KINEMATICS OF MESSIER 51.
1970/01/01 by Sungjong Kwak, Elana Brief, Denis Langlais +5 · 12 citations
Agricultural and Biological Sciences · Chemistry · Engineering · Pharmacology, Toxicology and Pharmaceutics · #Advancements in Transdermal Drug Delivery #Astronomy #Astrophysics #Bee Products Chemical Analysis #Biochemistry #Calorimetry #Ceramide #Chemical engineering #Chemistry #Chromatography #Classical mechanics #Content (measure theory) #Differential scanning calorimetry #Essential Oils and Antimicrobial Activity #Ethanol #Fourier transform infrared spectroscopy #Infrared spectroscopy #Kinematics #Membrane #Nuclear magnetic resonance spectroscopy #Organic chemistry #Physics #Spacecraft and Cryogenic Technologies #Stratum corneum