- Phytochemical inhibitors of squalene epoxidase: Integrated In silico and In vitro mechanistic insights for targeting cholesterol biosynthesis
2025/03/05 by Emadeldin M. Kamel, Doaa A. Abdelrheem, Bashir Salah +1 · 9 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Computer Science · Medicine · #Biochemistry #Biology #Biosynthesis #Chemistry #Cholesterol and Lipid Metabolism #Computational Drug Discovery Methods #Computational biology #Enzyme #Gene #In silico #In vitro #Phytochemical #Plant biochemistry and biosynthesis #Squalene #Squalene monooxygenase #Stereochemistry
- Herbal Multiomics Provide Insights into Gene Discovery and Bioproduction of Triterpenoids by Engineered Microbes
2024/12/12 by Feng Zhang, Xuemi Hao, Jia Liu +3 · 5 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · #Biochemistry #Biology #Bioproduction #Biosynthesis #Chemistry #Computational biology #Gene #Metabolic engineering #Metabolic pathway #Metabolism #Mevalonate pathway #Photosynthetic Processes and Mechanisms #Plant Gene Expression Analysis #Plant biochemistry and biosynthesis #Squalene #Triterpenoid
- Metabolic Engineering for Squalene Production: Advances and Perspectives
2024/12/03 by Liang Chai, Jiaxin Che, Qingsheng Qi +1 · 10 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Computer Science · Engineering · #Biochemical engineering #Biochemistry #Biology #Biotechnology #Chemistry #Computational Drug Discovery Methods #Engineering #Enzyme #Metabolic engineering #Microbial Metabolic Engineering and Bioproduction #Plant biochemistry and biosynthesis #Production (economics) #Squalene
- Engineering Saccharomyces cerevisiae for Hyperproduction of β-Amyrin by Mitigating the Inhibition Effect of Squalene on β-Amyrin Synthase
2021/12/25 by Mengmeng Du, Meng-Meng Du, Zhan-Tao Zhu +14 · 9 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · #Biochemistry #Chemistry #Compartmentalization (fire protection) #Cytosol #Endoplasmic Reticulum Stress and Disease #Enzyme #Fermentation #Industrial fermentation #Peroxisome #Peroxisome Proliferator-Activated Receptors #Plant biochemistry and biosynthesis #Receptor #Saccharomyces cerevisiae #Squalene #Triterpene #Yeast
- Metabolic Engineering of Saccharomyces cerevisiae To Overproduce Squalene
2020/01/28 by Tian Li, Guo-Song Liu, Wei Zhou +12 · 17 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Engineering · #Alcohol dehydrogenase #Biochemistry #Biofuel production and bioconversion #Biosynthesis #Chemistry #Enzyme #Ethanol #Farnesyl-diphosphate farnesyltransferase #Fermentation #Industrial and production engineering #Metabolic engineering #Microbial Metabolic Engineering and Bioproduction #Plant biochemistry and biosynthesis #Reductase #Squalene #Squalene monooxygenase #Yeast
- Commercial Cold Pressed Flaxseed Oils Quality and Oxidative Stability at the Beginning and the End of Their Shelf Life
2016/01/01 by Małgorzata Tańska, Beata Roszkowska, Marta Skrajda +1 · 1 citation
Chemistry · Nursing · Biochemistry, Genetics and Molecular Biology · #Edible Oils Quality and Analysis #Fatty Acid Research and Health #Protein Hydrolysis and Bioactive Peptides #Chemistry #Squalene #Food science #Peroxide value #Shelf life #Conjugated diene #Phenols #Organoleptic #Hydrolysis #Fatty acid #Composition (language) #Acid value #Food preservation #Organic chemistry #Biochemistry
- Introduction of ω-3 Desaturase Obviously Changed the Fatty Acid Profile and Sterol Content of Schizochytrium sp.
2015/10/23 by Lujing Ren, Lu-jing Ren, Xiaoyan Zhuang +6 · 14 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Energy · #Algal biology and biofuel production #Biochemistry #Biology #Chemistry #Cholesterol #Docosahexaenoic acid #Docosapentaenoic acid #Fatty acid #Food science #Gene #Lipid metabolism and biosynthesis #Metabolic engineering #Microbial Metabolic Engineering and Bioproduction #Polyunsaturated fatty acid #Squalene #Sterol
- Plasma cholesterol-lowering and transient liver dysfunction in mice lacking squalene synthase in the liver
2015/03/10 by Shuichi Nagashima, Hiroaki Yagyu, Ryuichi Tozawa +11 · 8 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Biochemistry #Biology #Biosynthesis #Chemistry #Cholesterol #Cholesterol and Lipid Metabolism #Endocrinology #Enzyme #Farnesyl-diphosphate farnesyltransferase #Farnesyltransferase #Internal medicine #Lipid metabolism and biosynthesis #Lipoprotein #Medicine #Plant biochemistry and biosynthesis #Reverse cholesterol transport #Squalene #Squalene monooxygenase #Sterol
- Catalytic Hydrogenation of Squalene to Squalane
2014/08/29 by Rosaria Ciriminna, Valerica Pandarus, François Béland +1 · 1 citation
Chemistry · Computer Science · Engineering · #Biochemical engineering #Catalysis #Catalysis for Biomass Conversion #Catalytic hydrogenation #Chemistry #Computational Drug Discovery Methods #Engineering #Hydrocarbon #Innovative Microfluidic and Catalytic Techniques Innovation #Natural product #Organic chemistry #Squalane #Squalene
- Identification of unique mechanisms for triterpene biosynthesis in Botryococcus braunii
2011/07/11 by Tom D. Niehaus, Shigeru Okada, Timothy P. Devarenne +3 · 1 citation
Biochemistry, Genetics and Molecular Biology · Medicine · Chemistry · #Plant biochemistry and biosynthesis #Microbial Natural Products and Biosynthesis #Microbial Metabolic Engineering and Bioproduction #Squalene #Botryococcus braunii #Triterpene #Farnesyl-diphosphate farnesyltransferase #Squalene monooxygenase #ATP synthase #Biosynthesis #Biochemistry #Biology #Enzyme #Stereochemistry #Sterol #Chemistry #Prenylation #Botany #Farnesyltransferase #Cholesterol
- Squalene-Hopene Cyclases
2011/04/30 by Gabriele Siedenburg, Dieter Jendrossek · 1 citation
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Antioxidant Activity and Oxidative Stress #Biochemistry #Biology #Chemistry #Cyclase #Enzyme #Hopanoids #Natural product bioactivities and synthesis #Plant biochemistry and biosynthesis #Squalene #Stereochemistry #Triterpene
- Epidermal surface lipids
2009/03/01 by Apostolos Pappas · 1 citation
Chemistry · Medicine · Pharmacology, Toxicology and Pharmaceutics · #Acne #Acne and Rosacea Treatments and Effects #Advancements in Transdermal Drug Delivery #Anatomy #Biochemistry #Biology #Blood lipids #Chemistry #Cholesterol #Dermatology and Skin Diseases #Endocrinology #Epidermis (zoology) #Sebaceous gland #Squalene #Stratum corneum #Wax
- Squalene and Squalane Emulsions as Adjuvants
1999/09/01 by A. C. Allison, Anthony C. Allison · 1 citation
Chemistry · Immunology and Microbiology · Medicine · #Antigen #Biochemistry #Biology #Chemistry #Immune system #Immunology #Immunotherapy and Immune Responses #In vitro #Monoclonal and Polyclonal Antibodies Research #Muramyl dipeptide #Pharmacology #Squalane #Squalene #T-cell and B-cell Immunology
- Volatile constituents of Dactylanthus taylorii flower nectar in relation to flower pollination and browsing by animals
1995/11/01 by C.E. Ecroyd, C. E. Ecroyd, Robert A. Franich +5 · 2 citations
Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · #Biochemical and biochemical processes #Biochemistry #Biology #Botany #Essential oil #Geraniol #Inflorescence #Nectar #Nerol #Phytochemistry and Biological Activities #Plant and animal studies #Pollen #Pollination #Squalene
- Human stratum corneum lipids: characterization and regional variations
1983/02/01 by Marilyn A. Lampe, A. L. Burlingame, J. E. Whitney +4 · 1 citation
Pharmacology, Toxicology and Pharmaceutics · Biochemistry, Genetics and Molecular Biology · Chemistry · #Advancements in Transdermal Drug Delivery #Lipid Membrane Structure and Behavior #Surfactants and Colloidal Systems #Stratum corneum #Sphingolipid #Chemistry #Biochemistry #Ceramide #Squalene #Fatty acid #Corneocyte #Barrier function #Chromatography #Cholesterol #Biophysics #Biology #Cell biology
- Zur Kenntnis der Triterpene. 190. Mitteilung. Eine stereochemische Interpretation der biogenetischen Isoprenregel bei den Triterpenen
1955/01/01 by A. Eschenmoser, Albert Eschenmoser, L. Ruzicka +3 · 16 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · #Biochemistry #Chemistry #Cholesterol #Friedelin #Lanosterol #Lupeol #Natural product bioactivities and synthesis #Organic chemistry #Phytochemical compounds biological activities #Plant biochemistry and biosynthesis #Squalene #Stereochemistry #Sterol #Terpene #Triterpene #Triterpenoid