1. Comparative Transcriptome Analysis of Key Reductase Genes Involved in the 1-Deoxynojirimycin Biosynthetic Pathway in Mulberry Leaves and Cloning, Prokaryotic Expression, and Functional Analysis of MaSDR1 and MaSDR2
   2020/10/21 by Jia Liu, Jingqiong Wan, Dujun Wang +3 · 7 citations
   Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Accession number (library science) #Biochemistry #Biology #Biosynthesis #Carbohydrate Chemistry and Synthesis #Cloning (programming) #Enzyme #GenBank #Gene #Gene expression #Microbial Natural Products and Biosynthesis #Plant biochemistry and biosynthesis #Reductase #Transcriptome
2. Metabolic Engineering of Saccharomyces cerevisiae To Overproduce Squalene
   2020/01/28 by Tian Li, Guo-Song Liu, Wei Zhou +12 · 17 citations
   Biochemistry, Genetics and Molecular Biology · Chemistry · Engineering · #Alcohol dehydrogenase #Biochemistry #Biofuel production and bioconversion #Biosynthesis #Chemistry #Enzyme #Ethanol #Farnesyl-diphosphate farnesyltransferase #Fermentation #Industrial and production engineering #Metabolic engineering #Microbial Metabolic Engineering and Bioproduction #Plant biochemistry and biosynthesis #Reductase #Squalene #Squalene monooxygenase #Yeast
3. Methyl (Alkyl)-Coenzyme M Reductases: Nickel F-430-Containing Enzymes Involved in Anaerobic Methane Formation and in Anaerobic Oxidation of Methane or of Short Chain Alkanes
   2019/04/05 by Rudolf K. Thauer · 40 citations
   Biochemistry, Genetics and Molecular Biology · Chemistry · Environmental Science · #Alkyl #Anaerobic oxidation of methane #Chemistry #Cofactor #Enzyme #Inorganic chemistry #Medicinal chemistry #Methane #Methane Hydrates and Related Phenomena #Methanogenesis #Methyl group #Microbial metabolism and enzyme function #Nickel #Organic chemistry #Porphyrin Metabolism and Disorders #Redox #Reductase #Stereochemistry
4. Production of Triterpene Ginsenoside Compound K in the Non-conventional Yeast Yarrowia lipolytica
   2019/02/13 by Dashuai Li, Yufen Wu, Chuanbo Zhang +3 · 29 citations
   Biochemistry, Genetics and Molecular Biology · Chemistry · Pharmacology, Toxicology and Pharmaceutics · #Biochemistry #Biology #Chemistry #Enzyme #Fermentation #Gene #Heterologous #Metabolic engineering #Mevalonate pathway #Microbial Metabolic Engineering and Bioproduction #Pharmacological Effects of Natural Compounds #Plant biochemistry and biosynthesis #Reductase #Strain (injury) #Triterpene #Yarrowia #Yeast
5. Uric acid activates aldose reductase and the polyol pathway for endogenous fructose and fat production causing development of fatty liver in rats
   2019/01/16 by Laura Gabriela Sánchez‐Lozada, Laura G. Sanchez-Lozada, Ana Andres-Hernando +10 · 27 citations
   Chemistry · Medicine · #Alcohol Consumption and Health Effects #Aldehyde Reductase #Aldose reductase #Biochemistry #Chemistry #Diet, Metabolism, and Disease #Endogeny #Enzyme #Fructose #Gout, Hyperuricemia, Uric Acid #Internal medicine #Medicine #Organic chemistry #Polyol #Polyol pathway #Reductase #Sorbitol #Uric acid
6. Roscovitine and purvalanol A effectively reverse anthracycline resistance mediated by the activity of aldo-keto reductase 1C3 (AKR1C3): A promising therapeutic target for cancer treatment
   2018/08/03 by Eva Novotná, Neslihan Büküm, Jakub Hofman +5 · 11 citations
   Biochemistry, Genetics and Molecular Biology · Medicine · #Alcohol Consumption and Health Effects #Aldo-keto reductase #Aldose Reductase and Taurine #Anthracycline #Biochemistry #Biology #Cancer #Cancer cell #Cancer research #Chemotherapy #Cofactor #Daunorubicin #Enzyme #Genetics #Heme Oxygenase-1 and Carbon Monoxide #NAD+ kinase #Pharmacology #Reductase
7. 5-Alpha reductase deficiency
   2014/10/15 by Ijeoma Okeigwe, Wendy Kuohung · 1 citation
   Biochemistry, Genetics and Molecular Biology · Medicine · #Sexual Differentiation and Disorders #Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities #Hormonal and reproductive studies #Dihydrotestosterone #Reductase #Testosterone (patch) #7-Dehydrocholesterol reductase #Enzyme #Alpha (finance) #Disorders of sex development #Medicine #Biology #Endocrinology #Androgen #Internal medicine #Biochemistry #Hormone
8. Streptococcus sanguinis Class Ib Ribonucleotide Reductase
   2014/01/01 by Olga V. Makhlynets, Amie K. Boal, DeLacy V. L. Rhodes +3 · 1 citation
   Chemistry · Medicine · #Metal-Catalyzed Oxygenation Mechanisms #Metal complexes synthesis and properties #Infective Endocarditis Diagnosis and Management #Ribonucleotide reductase #Thioredoxin reductase #Cofactor #Biochemistry #Streptococcus sanguinis #Glutaredoxin #Thioredoxin #Flavin adenine dinucleotide #Biology #Ribonucleotide #Reductase #Chemistry #Nucleotide #Enzyme #Streptococcus mutans #Bacteria #Genetics
9. Neuroprotective potential of atorvastatin and simvastatin (HMG-CoA reductase inhibitors) against 6-hydroxydopamine (6-OHDA) induced Parkinson-like symptoms
   2012/07/09 by Anil Kumar, Neha Sharma, Amit K. Gupta +3 · 23 citations
   Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · Neuroscience · #Atorvastatin #Biochemistry #Calpain Protease Function and Regulation #Chemistry #Disease #Endocrinology #Enzyme #HMG-CoA reductase #Hydroxydopamine #Inflammation #Internal medicine #Medicine #Neuroprotection #Nuclear Receptors and Signaling #Oxidative stress #Parkinson's Disease Mechanisms and Treatments #Parkinson's disease #Pharmacology #Reductase #Simvastatin
10. The 5 Alpha-Reductase Isozyme Family: A Review of Basic Biology and Their Role in Human Diseases
    2011/12/25 by Faris Azzouni, Alejandro Godoy, Yun Li +1 · 2 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Sexual Differentiation and Disorders #Urologic and reproductive health conditions #Urological Disorders and Treatments #Isozyme #Dihydrotestosterone #Testosterone (patch) #Reductase #Finasteride #Medicine #5 Alpha-Reductase Inhibitor #Alpha (finance) #Biology #Physiology #Androgen #Endocrinology #Prostate #Internal medicine #Cancer #Enzyme #Hormone #Biochemistry
11. A Review on Steroidal 5α-Reductase Inhibitors for Treatment of Benign Prostatic Hyperplasia
    2011/08/01 by Jingyuan Sun, Hua Xiang, Lin Yang +1 · 1 citation
    Medicine · Chemistry · #Hormonal Regulation and Hypertension #Urinary Bladder and Prostate Research #Prostate Cancer Treatment and Research #Finasteride #Dihydrotestosterone #Hyperplasia #Reductase #5 Alpha-Reductase Inhibitor #Medicine #Prostate #Enzyme #Pharmacology #Endocrinology #Androgen #Cancer research #Chemistry #Internal medicine #Biochemistry #Hormone #Cancer
12. An indomethacin analogue, N-(4-chlorobenzoyl)-melatonin, is a selective inhibitor of aldo-keto reductase 1C3 (type 2 3α-HSD, type 5 17β-HSD, and prostaglandin F synthase), a potential target for the treatment of hormone dependent and hormone independent malignancies
    2007/09/18 by Michael C. Byrns, Stephan Steckelbroeck, Trevor M. Penning +1 · 32 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Aldo-keto reductase #Aldose Reductase and Taurine #Biochemistry #Biology #Chemistry #Eicosanoids and Hypertension Pharmacology #Endocrinology #Enzyme #Hormone #Internal medicine #Medicine #Melatonin #Prenatal Substance Exposure Effects #Prostaglandin #Receptor #Reductase #Steroid
13. Investigations into the in vitro antimicrobial activity and mode of action of the phenazine antibiotic d-alanylgriseoluteic acid
    2006/12/23 by Stephen R. Giddens, David C. Bean · 11 citations
    Agricultural and Biological Sciences · Chemistry · Medicine · #Antibiotics #Antimicrobial #Antimicrobial Resistance in Staphylococcus #Biochemistry #Biology #Chemistry #Enzyme #Escherichia coli #Microbiology #Mode of action #Phenazine #Plant Pathogenic Bacteria Studies #Probiotics and Fermented Foods #Reductase #Streptococcus pneumoniae
14. Crystal Structure of NADP(H)-Dependent 1,5-Anhydro-d-fructose Reductase from Sinorhizobium morelense at 2.2 Å Resolution: Construction of a NADH-Accepting Mutant and Its Application in Rare Sugar Synthesis,
    2006/08/01 by Tresfore R. Dambe, Tresfore Dambe, Annette Kühn +4 · 9 citations
    Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Active site #Binding site #Biochemistry #Chemistry #Cofactor #Diet, Metabolism, and Disease #Enzyme #Metabolism, Diabetes, and Cancer #Moiety #Mutant #NAD+ kinase #Oxidoreductase #Plant nutrient uptake and metabolism #Reductase #Site-directed mutagenesis #Stereochemistry
15. Crystal Structures of Prostaglandin D2 11-Ketoreductase (AKR1C3) in Complex with the Nonsteroidal Anti-Inflammatory Drugs Flufenamic Acid and Indomethacin
    2004/03/01 by Andrew L. Lovering, Jon P. Ride, Christopher M. Bunce +3 · 26 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Active site #Aldo-keto reductase #Aldose Reductase and Taurine #Biochemistry #Cancer research #Chemistry #Eicosanoids and Hypertension Pharmacology #Enzyme #Flufenamic acid #Heme Oxygenase-1 and Carbon Monoxide #Medicine #Pharmacology #Prostaglandin #Reductase
16. Smith‐Lemli‐Opitz Syndrome and the DHCR7 Gene
    2003/05/01 by P. E. Jira, Petr Jira, H. R. Waterham +7 · 20 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #7-Dehydrocholesterol reductase #Biochemistry #Biology #Cancer, Lipids, and Metabolism #Cholesterol #Cholesterol and Lipid Metabolism #Endocrinology #Enzyme #Gene #Genetic disorder #Genetics #Internal medicine #Lipid metabolism and biosynthesis #Medicine #Mutation #Reductase #Smith–Lemli–Opitz syndrome #Sterol
17. Human Type 3 3α-Hydroxysteroid Dehydrogenase (Aldo-Keto Reductase 1C2) and Androgen Metabolism in Prostate Cells
    2003/04/22 by Tea Lanišnik Rižner, Hsueh Kung Lin, Donna M. Peehl +3 · 1 citation
    Biochemistry, Genetics and Molecular Biology · Medicine · Chemistry · #Aldose Reductase and Taurine #Prenatal Substance Exposure Effects #Hormonal and reproductive studies #Dihydrotestosterone #Aldo-keto reductase #Hydroxysteroid Dehydrogenases #Androgen #Dehydrogenase #Endocrinology #Biochemistry #Androgen receptor #Biology #Hydroxysteroid dehydrogenase #Internal medicine #Chemistry #Reductase #Prostate cancer #Enzyme #Hormone #Medicine #Cancer
18. Androgens and male physiology the syndrome of 5α-reductase-2 deficiency
    2002/12/01 by J Imperato-McGinley, Julianne Imperato‐McGinley, Yuan‐Shan Zhu +1 · 5 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Androgen #Biochemistry #Biology #Dihydrotestosterone #Endocrinology #Enzyme #Gene #Genetics #Hormonal and reproductive studies #Hormone #Internal medicine #Isozyme #Male pseudohermaphroditism #Medicine #Mesonephric duct #Reductase #Sexual Differentiation and Disorders #Sexual differentiation #Spermatogenesis #Testosterone (patch) #Urologic and reproductive health conditions #Virilization
19. Divergent members of a soybean (Glycine max L.) 4‐coumarate:coenzyme A ligase gene family
    2002/02/15 by Christian Lindermayr, Britta Möllers, Judith Fliegmann +4 · 26 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · #Amino acid #Biochemical and biochemical processes #Biochemistry #Biology #Chemistry #Coenzyme A #DNA ligase #Enzyme #Gene #Genetics #Glycine #Plant Gene Expression Analysis #Plant biochemistry and biosynthesis #Reductase
20. Novel inhibitors of 5α-reductase
    2002/02/01 by Fabrizio Machetti, Antonio Guarna · 1 citation
    Medicine · Biochemistry, Genetics and Molecular Biology · #Urinary Bladder and Prostate Research #Sexual Differentiation and Disorders #Hormonal and reproductive studies #Acne #Finasteride #hirsutism #Hyperplasia #Medicine #5 Alpha-Reductase Inhibitor #Male-pattern baldness #Reductase #Dermatology #Cancer #Enzyme #Pharmacology #Internal medicine #Prostate #Endocrinology #Biology #Biochemistry #Diabetes mellitus
21. Clinical application of 5α-reductase inhibitors
    2001/03/01 by A. Cilotti, Giovanna Danza, G. Danza +1 · 3 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #5 Alpha-Reductase Inhibitor #Acne #Biochemistry #Cancer #Chemistry #Dermatology #Diabetes mellitus #Endocrinology #Enzyme #Finasteride #Hormonal and reproductive studies #Internal medicine #Male-pattern baldness #Medicine #Pharmacology #Prostate #Reductase #Scalp #Sexual Differentiation and Disorders #Sexual function and dysfunction studies #Testosterone (patch) #Urology #hirsutism
22. Elucidating the Process of Activation of Methyl-Coenzyme M Reductase
    2001/01/01 by Divya Prakash, Yonnie Wu, Sang‐Jin Suh +3 · 29 citations
    Arts and Humanities · Biochemistry, Genetics and Molecular Biology · Chemistry · Energy · Neuroscience · #Active site #Biochemistry #Biology #Chemistry #Coenzyme A #Cofactor #Enzyme #French Historical and Cultural Studies #Metalloenzymes and iron-sulfur proteins #Neurological diseases and metabolism #Porphyrin Metabolism and Disorders #Reductase #Stereochemistry
23. Role of the Dinitrogenase Reductase Arginine 101 Residue in Dinitrogenase Reductase ADP-Ribosyltransferase Binding, NAD Binding, and Cleavage
    2001/01/01 by Yan Ma, Paul W. Ludden · 7 citations
    Biochemistry, Genetics and Molecular Biology · #Amino Acid Enzymes and Metabolism #Amino acid #Arginine #Bacteria #Bacterial Genetics and Biotechnology #Biochemistry #Biology #Enzyme #Enzyme Catalysis and Immobilization #Genetics #NAD+ kinase #Nitrogen fixation #Nitrogenase #Reductase
24. A novel function of yeast fatty acid synthase
    2000/05/01 by Fabienne Fichtlscherer, Christian Wellein, Maria Mittag +1 · 21 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · #Biochemistry #Biology #Chemistry #Coenzyme A #Cofactor #Enzyme #Fatty acid synthase #Fungal and yeast genetics research #Gene #In vitro #Mutant #Peroxisome Proliferator-Activated Receptors #Protein subunit #RNA and protein synthesis mechanisms #Reductase #Yeast
25. Steroid 5α-reductase inhibitors in androgen-dependent disorders
    1997/08/01 by Georgianna S Harris, G. S. Harris, John W. Kozarich +1 · 2 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #5 Alpha-Reductase Inhibitor #Androgen #Biochemistry #Biology #Chemistry #Computational biology #Enzyme #Finasteride #Hormonal and reproductive studies #Hormone #Internal medicine #Medicine #Pharmacology #Prostate #Prostate Cancer Treatment and Research #Reductase #Sexual Differentiation and Disorders #Steroid
26. The Enoyl‐[Acyl‐Carrier‐Protein] Reductase (FabI) of Escherichia coli, which Catalyzes a Key Regulatory Step in Fatty Acid Biosynthesis, Accepts NADH and NADPH as Cofactors and is Inhibited by Palmitoyl‐CoA
    1996/12/01 by Helmut Bergler, Sandra Fuchsbichler, Gregor Högenauer +1 · 26 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · Immunology and Microbiology · #Acyl carrier protein #Antimicrobial Peptides and Activities #Antimicrobial agents and applications #Biochemistry #Biology #Biosynthesis #Chemical Synthesis and Analysis #Coenzyme A #Cofactor #Enzyme #Escherichia coli #Gene #Reductase
27. Efficient Reduction of Lipoamide and Lipoic Acid by Mammalian Thioredoxin Reductase
    1996/08/01 by Elias S.J. Arnér, Jonas Nordberg, Arne Holmgren · 3 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · #Antioxidant #Biochemical Acid Research Studies #Biochemistry #Chemistry #Enzyme #Glutathione #Glutathione Transferases and Polymorphisms #Lipoic acid #Microbial metabolism and enzyme function #NAD+ kinase #Reductase #Thioredoxin reductase
28. The High-Level Expression in Escherichia coli of the Membrane-Bound Form of Human and Rat Cytochrome b5 and Studies on Their Mechanism of Function
    1994/08/01 by P L Holmans, P.L. Holmans, M.S. Shet +5 · 16 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · Environmental Science · Pharmacology, Toxicology and Pharmaceutics · #Biochemistry #Chemistry #Coenzyme Q – cytochrome c reductase #Cytochrome P450 reductase #Cytochrome b5 #Cytochrome c #Effects and risks of endocrine disrupting chemicals #Enzyme #Escherichia coli #Flavoprotein #Gene #Heme #Hemeprotein #Pharmacogenetics and Drug Metabolism #Receptor Mechanisms and Signaling #Recombinant DNA #Reductase
29. Electron Leakage from the Mitochondrial NADPH-Adrenodoxin Reductase-Adrenodoxin-P450scc (Cholesterol Side Chain Cleavage) System
    1993/09/01 by Israel Hanukoglu, I. Hanukoglu, R. Rapoport +3 · 1 citation
    Biochemistry, Genetics and Molecular Biology · Chemistry · Pharmacology, Toxicology and Pharmaceutics · #Adrenodoxin #Biochemistry #Chemistry #Cholesterol side-chain cleavage enzyme #Cytochrome P450 #Eicosanoids and Hypertension Pharmacology #Electron transfer #Enzyme #Kinetics #Pharmacogenetics and Drug Metabolism #Photochemistry #Radical #Receptor Mechanisms and Signaling #Reductase
30. Enzymic determination of free fatty acids in serum.
    1980/10/01 by Hiroaki Okabe, H Okabe, Y Uji +4 · 2 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Absorbance #Biochemistry #Chemistry #Chromatography #Coenzyme A #Cofactor #Enzyme #Fatty acid #Hydrogen peroxide #Metabolism and Genetic Disorders #Metabolomics and Mass Spectrometry Studies #Oxidase test #Peroxidase #Reductase #Renal function and acid-base balance #Standard curve #Yield (engineering)

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