- Uric acid activates aldose reductase and the polyol pathway for endogenous fructose and fat production causing development of fatty liver in rats
2019/01/16 by Laura Gabriela Sánchez‐Lozada, Laura G. Sanchez-Lozada, Ana Andrés-Hernando +10 · 27 citations
Chemistry · Medicine · #Alcohol Consumption and Health Effects #Aldehyde Reductase #Aldose reductase #Biochemistry #Chemistry #Diet, Metabolism, and Disease #Endogeny #Enzyme #Fructose #Gout, Hyperuricemia, Uric Acid #Internal medicine #Medicine #Organic chemistry #Polyol #Polyol pathway #Reductase #Sorbitol #Uric acid
- Mechanisms of Protein Stabilization and Prevention of Protein Aggregation by Glycerol
2009/10/09 by Vincent Vagenende, Miranda G. S. Yap, Miranda G.S. Yap +1 · 28 citations
Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · Chemistry · Materials Science · #Amphiphile #Aqueous solution #Biochemistry #Biophysics #Chemistry #Enzyme Structure and Function #Glycerol #Hydrophobic effect #Organic chemistry #Polymer #Polyol #Protein Structure and Dynamics #Protein aggregation #Proteins in Food Systems #Solvent
- A Role for the Polyol Pathway in the Early Neuroretinal Apoptosis and Glial Changes Induced by Diabetes in the Rat
2003/02/01 by Veronica Asnaghi, Chiara Gerhardinger, Todd Hoehn +2 · 29 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · Neuroscience · #Advanced Glycation End Products research #Aldehyde Reductase #Aldose Reductase and Taurine #Aldose reductase #Aldose reductase inhibitor #Apoptosis #Biochemistry #Biology #Chemistry #Diabetes mellitus #Endocrinology #Galactose #Galactosemia #Glial fibrillary acidic protein #Heme Oxygenase-1 and Carbon Monoxide #Immunohistochemistry #Internal medicine #Medicine #Neuroscience #Polyol #Polyol pathway #Retina #Retinal #Sorbinil #Sorbitol