- Multiple functions of pyruvate kinase M2 in various cell types
2021/07/26 by Yoon‐Beom Lee, Jung K. Min, Jung Ki Min +18 · 26 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Acetylation #Biochemistry #Biology #Cancer #Cancer cell #Cancer, Hypoxia, and Metabolism #Cell biology #Enzyme #Gene #Genetics #Glycogen Storage Diseases and Myoclonus #Glycolysis #Isozyme #Kinase #Metabolism, Diabetes, and Cancer #PKM2 #Phosphorylation #Protein kinase A #Pyruvate kinase
- The 5 Alpha-Reductase Isozyme Family: A Review of Basic Biology and Their Role in Human Diseases
2011/12/25 by Faris Azzouni, Alejandro Godoy, Yun Li +1 · 2 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Sexual Differentiation and Disorders #Urologic and reproductive health conditions #Urological Disorders and Treatments #Isozyme #Dihydrotestosterone #Testosterone (patch) #Reductase #Finasteride #Medicine #5 Alpha-Reductase Inhibitor #Alpha (finance) #Biology #Physiology #Androgen #Endocrinology #Prostate #Internal medicine #Cancer #Enzyme #Hormone #Biochemistry
- Protein kinase C in heart failure: a therapeutic target?
2008/11/18 by Suresh S. Palaniyandi, S. S. Palaniyandi, L. Sun +5 · 28 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Biochemistry #Biology #Cardiac Fibrosis and Remodeling #Cardiac electrophysiology and arrhythmias #Cardiac hypertrophy #Cardiology #Cell biology #Enzyme #Fibrosis #Heart failure #Inflammation #Internal medicine #Isozyme #Kinase #Medicine #Muscle hypertrophy #Myocardial infarction #Pathogenesis #Pressure overload #Protein kinase C #Signaling Pathways in Disease
- Structural Basis for Tumor Pyruvate Kinase M2 Allosteric Regulation and Catalysis,
2005/06/15 by Jill D. Dombrauckas, Bernard D. Santarsiero, Andrew D. Mesecar · 33 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Allosteric regulation #Biochemistry #Biology #Biophysics #Cancer, Hypoxia, and Metabolism #Chemistry #Enzyme #Erythrocyte Function and Pathophysiology #Glycolysis #Isozyme #Metabolism, Diabetes, and Cancer #PKM2 #Pyruvate kinase #Stereochemistry #Tetramer
- Androgens and male physiology the syndrome of 5α-reductase-2 deficiency
2002/12/01 by Julianne Imperato‐McGinley, J Imperato-McGinley, Yuan‐Shan Zhu +1 · 5 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Androgen #Biochemistry #Biology #Dihydrotestosterone #Endocrinology #Enzyme #Gene #Genetics #Hormonal and reproductive studies #Hormone #Internal medicine #Isozyme #Male pseudohermaphroditism #Medicine #Mesonephric duct #Reductase #Sexual Differentiation and Disorders #Sexual differentiation #Spermatogenesis #Testosterone (patch) #Urologic and reproductive health conditions #Virilization
- Cyclo‐oxygenase isoenzymes: physiological and pharmacological role
2000/05/29 by P. C. A. Kam, Peter Kam, A. U‐L. See · 25 citations
Biochemistry, Genetics and Molecular Biology · Medicine · Pharmacology, Toxicology and Pharmaceutics · #Adverse effect #Arachidonic acid #Biochemistry #Biology #Eicosanoids and Hypertension Pharmacology #Enzyme #Gene isoform #Immunology #Inflammation #Inflammatory mediators and NSAID effects #Internal medicine #Isozyme #Kidney #Medicine #Pharmacogenetics and Drug Metabolism #Pharmacology #Prostaglandin
- Effect of MK-386, a novel inhibitor of type 1 5 alpha-reductase, alone and in combination with finasteride, on serum dihydrotestosterone concentrations in men.
1996/08/01 by Jules I. Schwartz, Anne Van Hecken, P.J. De Schepper +10 · 4 citations
Biochemistry, Genetics and Molecular Biology · Medicine · Chemistry · #Sexual Differentiation and Disorders #Hormonal and reproductive studies #Hormonal Regulation and Hypertension #Finasteride #Dihydrotestosterone #Testosterone (patch) #5 Alpha-Reductase Inhibitor #Endocrinology #Internal medicine #Placebo #Isozyme #Alpha (finance) #Medicine #Androgen #Chemistry #Enzyme #Hormone #Prostate #Biochemistry #Surgery
- Purification, sequencing and characterization of pseudexin phospholipases A2 from Pseudechis porphyriacus (Australian red-bellied black snake)
1989/01/01 by James J. Schmidt, John L. Middlebrook · 2 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · #Amino acid #Antibody #Antiserum #Biochemistry #Biology #Chemistry #Enzyme #Genetics #Homology (biology) #Ion channel regulation and function #Isozyme #Molecular biology #Nicotinic Acetylcholine Receptors Study #Phospholipase #Phospholipase A #Phospholipase A2 #Snake venom #Venom #Venomous Animal Envenomation and Studies
- Genetic variation and phylogenies detected from isozyme markers in species of Lactuca
1986/09/01 by Rick Kesseli, R. V. Kesseli, R. W. Michelmore +1 · 3 citations
Agricultural and Biological Sciences · #Biology #Botany #Enzyme #Evolutionary biology #Food Quality and Safety Studies #Gene #Genetic variation #Genetics #Isozyme #Lactuca #Variation (astronomy)
- Effects of hypothalamic stimulation on gluconeogenesis and glycolysis in rat liver
1975/06/01 by T Shimazu, Takashi Shimazu, S Ogasawara +1 · 8 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Biochemical Acid Research Studies #Biochemistry #Biology #Chemistry #Endocrinology #Enzyme #Gluconeogenesis #Glycolysis #Hypothalamus #Internal medicine #Isozyme #Medicine #Metabolism #Metabolism, Diabetes, and Cancer #Pancreatic function and diabetes #Phosphoenolpyruvate carboxykinase #Pyruvate kinase #Stimulation