- Antisense oligonucleotide treatment in a preterm infant with early-onset SCN2A developmental and epileptic encephalopathy
2025/04/22 by Matias Wagner, Géza Berecki, Walid Fazeli +20 · 1 voice · 2 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Advanced biosensing and bioanalysis techniques #Cystic Fibrosis Research Advances #Ion channel regulation and function
- Capsaicin preferentially inhibits slow-inactivation sodium currents in insects
2025/01/29 by Masashi Kamezaki, Hisashi Nishiwaki · 1 citation
Neuroscience · Biochemistry, Genetics and Molecular Biology · #Ion Channels and Receptors #Neurobiology and Insect Physiology Research #Ion channel regulation and function
- Inactivation of CaV1 and CaV2 channels
2025/01/16 by Worawan B. Limpitikul, Ivy E. Dick · 1 citation
Biochemistry, Genetics and Molecular Biology · Medicine · #Ion channel regulation and function #Cardiac electrophysiology and arrhythmias #Nicotinic Acetylcholine Receptors Study
- Direct visualization of electric-field-stimulated ion conduction in a potassium channel
2025/01/01 by Bo-Ram Lee, BoRam Lee, K. Ian White +8 · 1 voice · 2 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Cardiac electrophysiology and arrhythmias #Electrochemical Analysis and Applications #Ion channel regulation and function
- Amyloid beta Aβ1-40 activates Piezo1 channels in brain capillary endothelial cells
2024/12/24 by Xin Rui Lim, Luc Willemse, Osama F. Harraz · 1 voice · 1 citation
Medicine · Biochemistry, Genetics and Molecular Biology · #Erythrocyte Function and Pathophysiology #Ion channel regulation and function #Lipid Membrane Structure and Behavior
- Structures of TASK-1 and TASK-3 K2P channels provide insight into their gating and dysfunction in disease
2024/12/04 by Peter Rory Hall, Thibault Jouen-Tachoire, Marcus Schewe +6 · 1 voice · 1 citation
Biochemistry, Genetics and Molecular Biology · Medicine · Neuroscience · #Cardiac electrophysiology and arrhythmias #Ion Channels and Receptors #Ion channel regulation and function
- Store-Operated Calcium Channels in the Nervous System
2024/11/25 by Kirill S. Korshunov, Murali Prakriya · 1 citation
Biochemistry, Genetics and Molecular Biology · Neuroscience · #Ion channel regulation and function #Neuroscience and Neuropharmacology Research #Neuroscience and Neural Engineering
- Interaction with the cysteine‐free protein <scp>HAX1</scp> expands the substrate specificity and function of <scp>MIA40</scp> beyond protein oxidation
2024/11/20 by Robin Alexander Rothemann, Dylan Stobbe, Michaela Nicole Hoehne‐Wiechmann +9 · 1 voice · 1 citation
Biochemistry, Genetics and Molecular Biology · #Blood disorders and treatments #Mitochondrial Function and Pathology #Ion channel regulation and function
- Pharmacology of PIEZO1 channels
2024/10/14 by Jacob A. Kinsella, Marjolaine Debant, Gregory Parsonage +6 · 20 citations
Medicine · Biochemistry, Genetics and Molecular Biology · #Erythrocyte Function and Pathophysiology #Hemoglobin structure and function #Ion channel regulation and function
- Piezo1, the new actor in cell volume regulation
2024/04/06 by A. Michelucci, Antonio Michelucci, L. Catacuzzeno +1 · 1 citation
Medicine · Biochemistry, Genetics and Molecular Biology · #Erythrocyte Function and Pathophysiology #Ion channel regulation and function #Blood properties and coagulation
- Anxiety control by astrocytes in the lateral habenula
2024/02/02 by Wanqin Tan, Yoko Ikoma, Yusuke Takahashi +4 · 3 voices · 4 citations
Biochemistry, Genetics and Molecular Biology · Neuroscience · #Ion channel regulation and function #Neuroscience and Neuropharmacology Research #Photoreceptor and optogenetics research
- Structure, Function, and Regulation of the Junctophilin Family
2023/11/06 by Duane D. Hall, Hiroshi Takeshima, Long-Sheng Song +1 · 1 citation
Biochemistry, Genetics and Molecular Biology · Neuroscience · #Ion channel regulation and function #Ion Channels and Receptors #Signaling Pathways in Disease
- Mechanosensing by Vascular Endothelium
2023/10/20 by Xin Rui Lim, Osama F. Harraz · 3 citations
Medicine · Biochemistry, Genetics and Molecular Biology · #Erythrocyte Function and Pathophysiology #Cellular Mechanics and Interactions #Ion channel regulation and function
- Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn2+ uptake into the Golgi apparatus
2023/08/08 by Han Ba Bui, Satoshi Watanabe, Norimichi Nomura +10 · 1 voice · 1 citation
Biochemistry, Genetics and Molecular Biology · Nursing · #Ion channel regulation and function #RNA and protein synthesis mechanisms #Trace Elements in Health
- Multiscale studies of delayed afterdepolarizations I: A comparison of two biophysically realistic mathematical models for human ventricular myocytes
2023/07/14 by Navneet Roshan, Rahul Pandit, Roshan, Navneet +1 · 1 citation
Biochemistry, Genetics and Molecular Biology · Engineering · Medicine · #Cardiac electrophysiology and arrhythmias #Electrostatic Discharge in Electronics #FOS: Biological sciences #Ion channel regulation and function #Tissues and Organs (q-bio.TO)
- Multiscale studies of delayed afterdepolarizations II: Calcium-overload-induced ventricular arrhythmias
2023/07/14 by Navneet Roshan, Rahul Pandit, Roshan, Navneet +1 · 1 citation
Biochemistry, Genetics and Molecular Biology · Medicine · #Cardiac electrophysiology and arrhythmias #FOS: Biological sciences #Ion channel regulation and function #Tissues and Organs (q-bio.TO)
- Physics of mechanotransduction by Piezo ion channels
2022/05/20 by Michael N. Young, Michael Young, Amanda H. Lewis +1 · 1 citation
Medicine · Biochemistry, Genetics and Molecular Biology · #Erythrocyte Function and Pathophysiology #Ion channel regulation and function #Chemical and Physical Studies
- Focused ultrasound excites action potentials in mammalian peripheral neurons in part through the mechanically gated ion channel PIEZO2
2022/05/17 by Benjamin U. Hoffman, Yoshichika Baba, Stephen A. Lee +3 · 1 voice · 1 citation
Engineering · Biochemistry, Genetics and Molecular Biology · #Ultrasound and Hyperthermia Applications #Ion channel regulation and function #Microbial Inactivation Methods
- The novel persistent sodium current inhibitor PRAX‐562 has potent anticonvulsant activity with improved protective index relative to standard of care sodium channel blockers
2022/01/17 by Kristopher M. Kahlig, Liam Scott, Robert J. Hatch +5 · 14 citations
Neuroscience · Biochemistry, Genetics and Molecular Biology · #Neuroscience and Neural Engineering #Neuroscience and Neuropharmacology Research #Ion channel regulation and function
- Voltage-dependent CaV3.2 and CaV2.2 channels in nociceptive pathways
2022/01/18 by Lucia Hoppanová, Lucia Hoppanova, Lubica Lacinova +1 · 1 citation
Medicine · Biochemistry, Genetics and Molecular Biology · #Pain Mechanisms and Treatments #Ion channel regulation and function #Botulinum Toxin and Related Neurological Disorders
- Structure, Function, and Pharmacology of Glutamate Receptor Ion Channels
2021/10/01 by Kasper B. Hansen, Lonnie P. Wollmuth, Derek Bowie +17 · 9 citations
Biochemistry, Genetics and Molecular Biology · Neuroscience · #Ion channel regulation and function #Neuroscience and Neuropharmacology Research #Nicotinic Acetylcholine Receptors Study
- Evidence that toxin resistance in poison birds and frogs is not rooted in sodium channel mutations and may rely on “toxin sponge” proteins
2021/07/02 by Fayal Abderemane-Ali, Nathan D. Rossen, Megan E. Kobiela +8 · 2 citations
Biochemistry, Genetics and Molecular Biology · Environmental Science · #Ion channel regulation and function #Nicotinic Acetylcholine Receptors Study #Marine Toxins and Detection Methods
- ENaC and ROMK channels in the connecting tubule regulate renal K+ secretion
2021/06/18 by Lei Yang, Yuanyuan Xu, Diego Gravotta +3 · 2 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Ion Transport and Channel Regulation #Ion channel regulation and function #Electrolyte and hormonal disorders
- Mechanosensitive ion channels in cell migration
2021/04/27 by Brenda Canales Coutiño, Roberto Mayor · 1 voice · 1 citation
Medicine · Biochemistry, Genetics and Molecular Biology · Neuroscience · #Erythrocyte Function and Pathophysiology #Ion channel regulation and function #Ion Channels and Receptors
- Structural Pharmacology of Voltage-Gated Sodium Channels
2021/03/29 by Sigrid Noreng, Tianbo Li, Jian Payandeh · 1 citation
Biochemistry, Genetics and Molecular Biology · Neuroscience · Medicine · #Ion channel regulation and function #Neuroscience and Neural Engineering #Cardiac electrophysiology and arrhythmias
- Sex‐Specific Classification of Drug‐Induced Torsade de Pointes Susceptibility Using Cardiac Simulations and Machine Learning
2021/03/26 by Alex Fogli Iseppe, Haibo Ni, Sicheng Zhu +9 · 26 citations
Medicine · Biochemistry, Genetics and Molecular Biology · #Cardiac electrophysiology and arrhythmias #Ion channel regulation and function #Receptor Mechanisms and Signaling
- Malignant hyperthermia 2020
2021/01/05 by Philip M. Hopkins, P. M. Hopkins, Thierry Girard +9 · 25 citations
Biochemistry, Genetics and Molecular Biology · Engineering · Medicine · #Ion channel regulation and function #Ultrasound and Hyperthermia Applications #Cardiac electrophysiology and arrhythmias
- Coronary endothelial dysfunction prevented by small-conductance calcium-activated potassium channel activator in mice and patients with diabetes
2020/02/19 by Zhiqi Zhang, Guangbin Shi, Yuhong Liu +12 · 2 citations
Medicine · Biochemistry, Genetics and Molecular Biology · #Nitric Oxide and Endothelin Effects #Cardiac Ischemia and Reperfusion #Ion channel regulation and function
- Ca<sup>2+</sup> signalling in fibroblasts and the therapeutic potential of K<sub>Ca</sub>3.1 channel blockers in fibrotic diseases
2019/11/23 by Katy M. Roach, Peter Bradding · 27 citations
Medicine · Biochemistry, Genetics and Molecular Biology · #Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis #Ion channel regulation and function #Cardiac electrophysiology and arrhythmias
- N-Terminal Domains of Cardiac Myosin Binding Protein C Cooperatively Activate the Thin Filament
2018/09/27 by Cristina Risi, Cristina M. Risi, Betty Belknap +5 · 1 citation
Medicine · Biochemistry, Genetics and Molecular Biology · #Cardiomyopathy and Myosin Studies #Cardiovascular Effects of Exercise #Ion channel regulation and function
more