Structure, Function, and Pharmacology of Glutamate Receptor Ion Channels

2021/10/01 by Kasper B. Hansen, Lonnie P. Wollmuth, Derek Bowie +17 · 9 citations
Biochemistry, Genetics and Molecular Biology · Neuroscience · #Ion channel regulation and function #Neuroscience and Neuropharmacology Research #Nicotinic Acetylcholine Receptors Study

paper · pdf · doi:10.1124/pharmrev.120.000131

openalex publication_date 2021/10/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28

Citations

• The receptor subunits generating NMDA receptor mediated currents in oligodendrocytes
• Effect of acute NR2B antagonist treatment on long-term potentiation in the rat hippocampus
• Differential effects of NMDA receptor antagonists at lower and higher doses on basal gamma band oscillation power in rat cortical electroencephalograms
• Spatiotemporally Graded NMDA Spike/Plateau Potentials in Basal Dendrites of Neocortical Pyramidal Neurons
• Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction
• A Randomized Trial of an N-methyl-D-aspartate Antagonist in Treatment-Resistant Major Depression
• Recent advances in the phencyclidine model of schizophrenia
• Structural Determinants of Agonist Efficacy at the Glutamate Binding Site of N-Methyl-d-Aspartate Receptors
• GluN2D-Containing N-methyl-d-Aspartate Receptors Mediate Synaptic Transmission in Hippocampal Interneurons and Regulate Interneuron Activity
• Structure, function, and allosteric modulation of NMDA receptors

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• The architecture of invaginating rod synapses slows glutamate diffusion and shapes synaptic responses
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