THE HYDROGEN CONTENT AND KINEMATICS OF MESSIER 51.

1970/01/01 by Sungjong Kwak, Elana Brief, Denis Langlais +5 · 12 citations
Agricultural and Biological Sciences · Chemistry · Engineering · Pharmacology, Toxicology and Pharmaceutics · #Advancements in Transdermal Drug Delivery #Astronomy #Astrophysics #Bee Products Chemical Analysis #Biochemistry #Calorimetry #Ceramide #Chemical engineering #Chemistry #Chromatography #Classical mechanics #Content (measure theory) #Differential scanning calorimetry #Essential Oils and Antimicrobial Activity #Ethanol #Fourier transform infrared spectroscopy #Infrared spectroscopy #Kinematics #Membrane #Nuclear magnetic resonance spectroscopy #Organic chemistry #Physics #Spacecraft and Cryogenic Technologies #Stratum corneum

paper · pdf · doi:10.1016/j.bbamem.2012.02.013

published in Biochimica et Biophysica Acta (BBA) - Biomembranes 6(5), 165-172 (Elsevier BV)

openalex publication_date 1970/01/01 · openalex created_date 2016/06/24 · openalex updated_date 2026/07/31

Abstract

Ethanol is used in a variety of topical products. It is known to enhance the permeability of the skin by altering the ability of the stratum corneum (SC) intercellular membranes to form an effective barrier. In addition, ethanol and other alcohols are key components of antiseptic gels currently used for hand wash. Using infrared and deuterium NMR spectroscopy as well as calorimetry, we have investigated the effect of ethanol on a model membrane composed of lipids representing the three classes of SC lipids, an equimolar mixture of N-palmitoylsphingosine (ceramide), palmitic acid and cholesterol. Ethanol is found to influence the membrane in a dose dependent manner, disrupting packing and increasing lipid motion at low concentrations and selectively extracting lipids at moderate concentrations.

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