- Dissecting the RNA-binding capacity of the multi-RRM protein Rrm4 essential for endosomal mRNA transport
2026/03/19 by Nina Kim Stoffel, Srimeenakshi Sankaranarayanan, Kira Müntjes +4 · 2 voices
Biochemistry, Genetics and Molecular Biology · #Binding site #Endosome #Function (biology) #Messenger RNA #Nuclear Structure and Function #Plasma protein binding #RNA #RNA Research and Splicing #RNA modifications and cancer #RNA-binding protein #Regulon #Transport protein
- Micronuclear collapse from oxidative damage
2024/08/29 by Melody Di Bona, Yanyang Chen, Albert S. Agustinus +35 · 29 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · #Biochemistry #Biology #Cell biology #Chemistry #Chromatin #Cytosol #DNA #ESCRT #Endosome #Intracellular #Micronucleus test #Microtubule and mitosis dynamics #Mitochondrial Function and Pathology #Mitochondrion #Nuclear Structure and Function #Reactive oxygen species
- Loss of HD-PTP function results in lipodystrophy, defective cellular signaling and altered lipid homeostasis
2024/08/19 by Destiny F. Schultz, Brian A. Davies, Johanna A. Payne +23 · 1 citation
Biochemistry, Genetics and Molecular Biology · Medicine · #Biology #Cardiomyopathy and Myosin Studies #Cell biology #ESCRT #Endocrinology #Endosome #Homeostasis #Internal medicine #Nuclear Structure and Function #Protein Tyrosine Phosphatases #Signal transduction
- Human antigen R transfers miRNA to Syntaxin 5 to synergize miRNA export from activated macrophages
2024/03/14 by Sourav Hom Choudhury, Shreya Bhattacharjee, Kamalika Mukherjee +1 · 5 citations
Biochemistry, Genetics and Molecular Biology · #Biochemistry #Biology #Cell biology #Cellular transport and secretion #Endoplasmic reticulum #Endosome #Gene #Intracellular #Phagosome #RNA regulation and disease #Signaling Pathways in Disease #microRNA
- HuR–miRNA complex activates RAS GTPase RalA to facilitate endosome targeting and extracellular export of miRNAs
2024/02/14 by Syamantak Ghosh, Sourav Hom Choudhury, Kamalika Mukherjee +1 · 7 citations
Biochemistry, Genetics and Molecular Biology · #Biochemistry #Biology #Cell #Cell biology #ESCRT #Endocytic cycle #Endocytosis #Endosome #Enzyme #Extracellular #Extracellular vesicle #Extracellular vesicles in disease #GTPase #Gene #Intracellular #Lysosome #MicroRNA in disease regulation #Microvesicles #RNA Interference and Gene Delivery #Rab #Signal transduction #Small GTPase #microRNA
- Lysosome-related organelles contain an expansion compartment that mediates delivery of zinc transporters to promote homeostasis
2024/02/08 by Adelita D. Mendoza, Nicholas Dietrich, Chieh-Hsiang Tan +7 · 14 citations
Chemistry · Environmental Science · Nursing · #Biochemistry #Biology #Cell biology #Chemistry #Compartment (ship) #Endosome #Enzyme #Gene #Heavy Metal Exposure and Toxicity #Homeostasis #Intracellular #Lysosome #Organelle #Selenium in Biological Systems #Trace Elements in Health #Transporter #Zinc #Zinc deficiency (plant disorder)
- Concurrent depletion of Vps37 proteins evokes ESCRT-I destabilization and profound cellular stress responses
2021/01/01 by Krzysztof Kolmus, Purevsuren Erdenebat, Ewelina Szymańska +14 · 18 citations
Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · Medicine · #Biology #Biomedical Research and Pathophysiology #Cell biology #Cellular transport and secretion #ESCRT #Endosome #Fight-or-flight response #Gene #Genetics #Intracellular #Phagocytosis and Immune Regulation
- A cancer-associated polymorphism in ESCRT-III disrupts the abscission checkpoint and promotes genome instability
2018/09/04 by Jessica B.A. Sadler, Jessica B. A. Sadler, Dawn M. Wenzel +10 · 29 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Abscission #Biology #Cancer #Cancer research #Cell #Cell biology #Cell cycle #Cell cycle checkpoint #Cell division #Cellular transport and secretion #Chromosome #Chromosome instability #Chromosome segregation #Cytokinesis #DNA #DNA damage #ESCRT #Endosome #G2-M DNA damage checkpoint #Gene #Genetics #Genome instability #Microtubule and mitosis dynamics #Midbody #Mitosis #Renal Diseases and Glomerulopathies
- Protein kinase C affects the internalization and recycling of organic anion transporting polypeptide 1B1
2015/05/23 by Mei Hong, Weifang Hong, Chunxu Ni +2 · 23 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · Pharmacology, Toxicology and Pharmaceutics · #Activator (genetics) #Amino Acid Enzymes and Metabolism #Biochemistry #Biology #Cell #Cell biology #Chemistry #Drug Transport and Resistance Mechanisms #Endosome #Gene #Internalization #Intracellular #Organic anion transporter 1 #Organic anion-transporting polypeptide #Pharmacogenetics and Drug Metabolism #Phosphorylation #Protein kinase C #Receptor #Transport protein #Transporter
- Extracellular vesicles: Exosomes, microvesicles, and friends
2013/02/18 by Graça Raposo, Willem Stoorvogel · 68 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Biochemistry #Biology #Cell biology #Cytosol #Endosome #Exosome #Extracellular #Extracellular vesicle #Extracellular vesicles #Extracellular vesicles in disease #Function (biology) #Intracellular #Membrane #MicroRNA in disease regulation #Microvesicle #Microvesicles #Vesicle #Viral Infections and Vectors #microRNA
- Exosomes: Looking back three decades and into the future
2013/02/18 by Clifford V. Harding, John E. Heuser, Philip D. Stahl · 28 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Biogenesis #Biology #Cell biology #Endosome #Exocytosis #Extracellular vesicles #Extracellular vesicles in disease #Genetics #Intracellular #Membrane #MicroRNA in disease regulation #Microvesicles #Viral Infections and Vectors #microRNA
- Quantum Dots with Phenylboronic Acid Tags for Specific Labeling of Sialic Acids on Living Cells
2010/12/23 by Aiping Liu, Shuo Peng, Jian Chow Soo +3 · 14 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Advanced biosensing and bioanalysis techniques #Biochemistry #Bioorthogonal chemistry #Biophysics #Cell #Cell biology #Chemistry #Click chemistry #Combinatorial chemistry #Endocytic cycle #Endocytosis #Endosome #Glycan #Glycoprotein #Glycosylation and Glycoproteins Research #Internalization #Live cell imaging #Living cell #Membrane #Monoclonal and Polyclonal Antibodies Research #Nanotechnology #Phenylboronic acid #Quantum dot #Sialic acid
- Artesunate Activates Mitochondrial Apoptosis in Breast Cancer Cells via Iron-catalyzed Lysosomal Reactive Oxygen Species Production
2010/12/14 by Anne Hamacher-Brady, Anne Hamacher‐Brady, Henning Stein +10 · 29 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Apoptosis #Autophagy #Autophagy in Disease and Therapy #Bafilomycin #Biochemistry #Biology #Calcium signaling and nucleotide metabolism #Cancer #Cancer cell #Cell biology #Chemistry #Endosome #Enzyme #Intracellular #Lysosome #Mitochondrion #Mosquito-borne diseases and control #Programmed cell death #Reactive oxygen species
- Secretory Mechanisms and Intercellular Transfer of MicroRNAs in Living Cells
2010/03/30 by Nobuyoshi Kosaka, Haruhisa Iguchi, Yusuke Yoshioka +3 · 38 citations
Biochemistry, Genetics and Molecular Biology · #Apoptosis #Biochemistry #Biology #Cell biology #Ceramide #Endosome #Exocytosis #Exosome #Extracellular #Extracellular vesicle #Extracellular vesicles in disease #Gene #Gene silencing #Golgi apparatus #Intracellular #MicroRNA in disease regulation #Microvesicles #RNA #RNA interference #Secretion #Secretory Vesicle #Secretory pathway #Sphingolipid Metabolism and Signaling #microRNA
- Lysosomal Degradation of α-Synuclein in Vivo
2010/03/04 by Sally K. Mak, Alison L. McCormack, Amy B. Manning-Boğ +4 · 28 citations
Chemistry · Medicine · #Alpha-synuclein #Alzheimer's disease research and treatments #Autophagy #Biochemistry #Biology #Cell biology #Chemistry #Endosome #Heat shock protein #In vitro #In vivo #Intracellular #LAMP1 #Lysosomal Storage Disorders Research #Lysosome #Medicine #Neurodegeneration #Parkinson's Disease Mechanisms and Treatments #Parkinson's disease #Parkinsonism #Pathology #Protein aggregation #Protein degradation
- EHD1 regulates cholesterol homeostasis and lipid droplet storage
2007/04/17 by Naava Naslavsky, Juliati Rahajeng, Debora Rapaport +2 · 20 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Biochemistry #Biology #Cell biology #Chemistry #Cholesterol #Cholesterol and Lipid Metabolism #Endocytic cycle #Endocytosis #Endosome #Foam cell #Glycosylation and Glycoproteins Research #Internalization #Intracellular #LDL receptor #Lipid droplet #Lipid metabolism #Lipid metabolism and biosynthesis #Lipoprotein #Organelle #Receptor #Reverse cholesterol transport #Triglyceride
- Human microglial cells express a functional IL-12 receptor and produce IL-12 following IL-12 stimulation
2001/11/01 by Yassine Taoufik, Marie-Ghislaine de Goër de Herve, Marie-Ghislaine de Goër de Herve +8 · 10 citations
Immunology and Microbiology · Medicine · Neuroscience · #Biochemistry #Biology #Cell biology #Chemokine receptors and signaling #Colocalization #Cytotoxic T cell #Endosome #Immune Response and Inflammation #In vitro #Interleukin 12 #Intracellular #Molecular biology #Neuroinflammation and Neurodegeneration Mechanisms #Neuroscience #Phosphorylation #Receptor #Stimulation #Tyrosine phosphorylation
- Phagocytic Uptake ofEncephalitozoon cuniculiby Nonprofessional Phagocytes
2000/12/01 by Sabine Couzinet, Elisabeth Cejas, Johannes C. Schittny +3 · 1 citation
Immunology and Microbiology · Medicine · #Parasitic Infections and Diagnostics #Toxoplasma gondii Research Studies #Dermatological diseases and infestations #Encephalitozoon cuniculi #Spore #Biology #Phagocytosis #Microsporidia #Microbiology #Phagosome #Vacuole #Internalization #Intracellular #Endosome #Phagocyte #Cytoplasm #Cytochalasin B #Cell biology #Cell #Biochemistry
- The biogenesis and properties of the parasitophorous vacuoles that harbour Leishmania in murine macrophages
1998/10/01 by Jean-Claude Antoine, Eric Prina, Thierry Lang +1 · 1 citation
Immunology and Microbiology · Medicine · #Amastigote #Antigen #Biogenesis #Biology #Cell #Cell biology #Cytoplasm #Endocytic cycle #Endocytosis #Endosome #Gene #Genetics #Immunology #Intracellular #Kinetoplastida #Leishmania #Major histocompatibility complex #Microbiology #Organelle #Organelle biogenesis #Parasite hosting #Parasites and Host Interactions #Protozoa #Protozoal disease #Research on Leishmaniasis Studies #Trypanosoma species research and implications #Vacuole
- Endocytosis and intracellular processing accompanying transfection mediated by cationic liposomes
1996/01/01 by Daniel S Friend, Daniel S. Friend, Demetrios Papahadjopoulos +3 · 24 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Materials Science · #Advanced biosensing and bioanalysis techniques #Biochemistry #Biology #Biophysics #Cationic liposome #Cell #Cell biology #Chemistry #Cytoplasm #Endocytosis #Endosome #Intracellular #Liposome #Membrane #Nanoparticle-Based Drug Delivery #RNA Interference and Gene Delivery #Transfection #Vesicle