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  1. Ergothioneine and mitochondria: An important protective mechanism?
    2024/06/19 by Zachary Weijie Fong, Richard Ming Yi Tang, Richard M. Y. Tang +6 · 8 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · Pharmacology, Toxicology and Pharmaceutics · #Biochemical Acid Research Studies #Biochemistry #Biology #Cell biology #Chemistry #Ergothioneine #Fungal Biology and Applications #Gene #Mitochondrial DNA #Mitochondrial disease #Mitochondrion #Pharmacological Effects of Natural Compounds #Transporter
  2. Lysosome-related organelles contain an expansion compartment that mediates delivery of zinc transporters to promote homeostasis
    2024/02/08 by Adelita D. Mendoza, Nicholas Dietrich, Chieh-Hsiang Tan +7 · 14 citations
    Chemistry · Environmental Science · Nursing · #Biochemistry #Biology #Cell biology #Chemistry #Compartment (ship) #Endosome #Enzyme #Gene #Heavy Metal Exposure and Toxicity #Homeostasis #Intracellular #Lysosome #Organelle #Selenium in Biological Systems #Trace Elements in Health #Transporter #Zinc #Zinc deficiency (plant disorder)
  3. A Metabolomic Analysis of Sensitivity and Specificity of 23 Previously Proposed Biomarkers for Renal Transporter‐Mediated Drug‐Drug Interactions
    2023/08/04 by Arne Gessner, Fabian Müller, Pia Wenisch +4 · 12 citations
    Chemistry · Medicine · Pharmacology, Toxicology and Pharmaceutics · #Biochemistry #Bioinformatics #Biology #Chemistry #Computational biology #Drug #Drug Transport and Resistance Mechanisms #Medicine #Metabolomics #Pharmacogenetics and Drug Metabolism #Pharmacological Effects and Toxicity Studies #Pharmacology #Transporter
  4. Macrophage angiotensin-converting enzyme reduces atherosclerosis by increasing peroxisome proliferator-activated receptor α and fundamentally changing lipid metabolism
    2023/05/24 by DuoYao Cao, Duo‐Yao Cao, Zakir Khan +28 · 25 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #ABCA1 #Angiotensin-converting enzyme #Biochemistry #Biology #CD36 #Chemistry #Cholesterol #Cholesterol and Lipid Metabolism #Efferocytosis #Endocrinology #Foam cell #Internal medicine #Lipid metabolism #Lipoprotein #Macrophage #Medicine #Peroxisome Proliferator-Activated Receptors #Peroxisome proliferator-activated receptor #Receptor #Renin-Angiotensin System Studies #Scavenger receptor #Transporter
  5. Thyroid-Disrupting Effects of Exposure to Fipronil and Its Metabolites from Drinking Water Based on Human Thyroid Follicular Epithelial Nthy-ori 3-1 Cell Lines
    2023/04/06 by Jianhui Zhuang, Zhiqiang Jiang, Dawei Chen +5 · 6 citations
    Agricultural and Biological Sciences · Chemistry · Environmental Science · Medicine · #Biochemistry #Biology #Chemistry #Endocrinology #Environmental Toxicology and Ecotoxicology #Fipronil #Follicular cell #Insect and Pesticide Research #Internal medicine #Medicine #Pesticide #Pesticide Exposure and Toxicity #Sodium-iodide symporter #Symporter #Thyroid #Thyroid cancer #Thyroid function #Thyroid peroxidase #Transporter
  6. Recent advances in the regulation of ABCA1 and ABCG1 by lncRNAs
    2021/02/02 by Shun Zhang, Lu Li, Jie Wang +5 · 18 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #ABCA1 #ABCG1 #Biochemistry #Biology #Cancer research #Cancer-related molecular mechanisms research #Cell biology #Cholesterol #Cholesterol and Lipid Metabolism #Coronary atherosclerosis #Coronary heart disease #Downregulation and upregulation #Efflux #GAS5 #Gene #Genetics #Internal medicine #Long non-coding RNA #MALAT1 #MEG3 #Medicine #MicroRNA in disease regulation #Transporter
  7. Maternal malnutrition impacts placental morphology and transporter expression: an origin for poor offspring growth
    2020/01/08 by Kristin L. Connor, Kristin L Connor, Mark Kibschull +9 · 1 citation
    Medicine · Nursing · #Biology #Birth, Development, and Health #Child Nutrition and Water Access #Gene #Genetics #Internal medicine #Malnutrition #Medicine #Morphology (biology) #Offspring #Physiology #Pregnancy #Pregnancy and preeclampsia studies #Transporter
  8. Physiology and Pathophysiology of Steroid Biosynthesis, Transport and Metabolism in the Human Placenta
    2018/09/12 by Waranya Chatuphonprasert, Kanokwan Jarukamjorn, Isabella Ellinger · 1 citation
    Medicine · Immunology and Microbiology · Chemistry · #Pregnancy and preeclampsia studies #Pregnancy and Medication Impact #Reproductive System and Pregnancy #Placenta #Organic anion transporter 1 #Endocrinology #Internal medicine #ABCA1 #Biology #Estrogen #Scavenger receptor #Steroid hormone #Hormone #Fetus #Chemistry #Cholesterol #Transporter #Biochemistry #Lipoprotein #Medicine #Pregnancy
  9. Berberine alleviates hepatic lipid accumulation by increasing ABCA1 through the protein kinase C δ pathway
    2018/03/02 by Hui Liang, Yutong Wang · 17 citations
    Chemistry · Medicine · #ABCA1 #Apolipoprotein B #Berberine #Berberine and alkaloids research #Biochemistry #Biology #Chemistry #Cholesterol #Cholesterol and Lipid Metabolism #Drug Transport and Resistance Mechanisms #Endocrinology #Fatty liver #Internal medicine #Lipid metabolism #Medicine #Phosphorylation #Protein kinase A #Protein kinase C #Rottlerin #Steatohepatitis #Transporter
  10. Hyperuricemia enhances intracellular urate accumulation via down-regulation of cell-surface BCRP/ABCG2 expression in vascular endothelial cells
    2018/01/06 by Hisakazu Komori, Kazuyuki Yamada, Ikumi Tamai · 25 citations
    Chemistry · Medicine · #ATP-binding cassette transporter #Abcg2 #Alcohol Consumption and Health Effects #Biochemistry #Biology #Bone and Joint Diseases #Chemistry #Endocrinology #Endothelial dysfunction #Gout, Hyperuricemia, Uric Acid #Hyperuricemia #Internal medicine #Medicine #NADPH oxidase #Oxidative stress #Transporter #Uric acid
  11. A novel small molecule liver X receptor transcriptional regulator, nagilactone B, suppresses atherosclerosis in apoE-deficient mice
    2016/07/26 by Yuzhou Gui, Sheng Yao, Hong Yan +7 · 10 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · Nursing · #ABCA1 #ABCG1 #Apolipoprotein B #Apolipoprotein E #Biochemistry #Cancer, Lipids, and Metabolism #Chemistry #Cholesterol #Cholesterol and Lipid Metabolism #Endocrinology #Fatty Acid Research and Health #Geranylgeranyl pyrophosphate #Internal medicine #Lipoprotein #Liver X receptor #Liver X receptor alpha #Medicine #Nuclear receptor #Reverse cholesterol transport #Transcription factor #Transporter
  12. Dihydrotestosterone treatment rescues the decline in protein synthesis as a result of sarcopenia in isolated mouse skeletal muscle fibres
    2016/04/25 by Oskar Wendowski, Zoe Redshaw, Gabriel Mutungi · 1 citation
    Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Ageing #Amino Acid Enzymes and Metabolism #Amino acid #Amino acid transporter #Biochemistry #Chemistry #Endocrinology #Gene #Genetics and Physical Performance #Internal medicine #Medicine #Muscle metabolism and nutrition #Sarcopenia #Skeletal muscle #Transporter
  13. Invited review: Architectures and mechanisms of ATP binding cassette proteins
    2016/04/02 by Karl‐Peter Hopfner · 25 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #ATP-binding cassette transporter #ATPase #Biochemistry #Biology #Biophysics #Cell biology #Chemistry #Computational biology #DNA #DNA Repair Mechanisms #Drug Transport and Resistance Mechanisms #Enzyme #Function (biology) #Gene #RNA and protein synthesis mechanisms #Transporter
  14. Protein kinase C affects the internalization and recycling of organic anion transporting polypeptide 1B1
    2015/05/23 by Mei Hong, Weifang Hong, Chunxu Ni +2 · 23 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · Pharmacology, Toxicology and Pharmaceutics · #Activator (genetics) #Amino Acid Enzymes and Metabolism #Biochemistry #Biology #Cell #Cell biology #Chemistry #Drug Transport and Resistance Mechanisms #Endosome #Gene #Internalization #Intracellular #Organic anion transporter 1 #Organic anion-transporting polypeptide #Pharmacogenetics and Drug Metabolism #Phosphorylation #Protein kinase C #Receptor #Transport protein #Transporter
  15. Functional mechanisms of neurotransmitter transporters regulated by lipid–protein interactions of their terminal loops
    2015/04/09 by George Khelashvili, Harel Weinstein · 13 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · Neuroscience · #Biochemistry #Biology #Cell biology #Chemistry #Efflux #Lipid Membrane Structure and Behavior #Lipid raft #Membrane #Neuroscience and Neuropharmacology Research #Neurotransmitter #Neurotransmitter transporter #Receptor #Receptor Mechanisms and Signaling #Reuptake #Reuptake inhibitor #Serotonin #Symporter #Synaptic cleft #Transporter
  16. Molecular mechanisms governing different pharmacokinetics of ginsenosides and potential for ginsenoside‐perpetrated herb–drug interactions on OATP 1 B 3
    2014/10/09 by Rongrong Jiang, Jiajia Dong, Xiuxue Li +8 · 23 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #ATP-binding cassette transporter #Bile Salt Export Pump #Biochemistry #Biology #Chemistry #Drug Transport and Resistance Mechanisms #Ginseng #Ginseng Biological Effects and Applications #Ginsenoside #Medicine #Multidrug resistance-associated protein 2 #Panax notoginseng #Pharmacokinetics #Pharmacology #Protopanaxadiol #Traditional Chinese Medicine Analysis #Transporter
  17. Korean, Japanese, and Chinese populations featured similar genes encoding drug-metabolizing enzymes and transporters
    2014/07/16 by SoJeong Yi, Hyungmi An, Howard Lee +16 · 1 citation
    Pharmacology, Toxicology and Pharmaceutics · Medicine · Biochemistry, Genetics and Molecular Biology · #Pharmacogenetics and Drug Metabolism #Drug Transport and Resistance Mechanisms #Metabolism and Genetic Disorders #Gene #Genetics #Biology #Transporter #Pharmacogenetics #Drug #Enzyme #Computational biology #Pharmacology #Genotype #Biochemistry
  18. Spectrins: A structural platform for stabilization and activation of membrane channels, receptors and transporters
    2013/05/11 by Beata Machnicka, Aleksander Czogalla, Anita Hryniewicz‐Jankowska +5 · 28 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · Neuroscience · #Biochemistry #Biology #Cell #Cell biology #Cell surface receptor #Chemistry #Cytoskeleton #Erythrocyte Function and Pathophysiology #Ion channel regulation and function #Neuroscience #Receptor #Signal transduction #Spectrin #Transmembrane protein #Transporter #Venomous Animal Envenomation and Studies
  19. High Specificity in Response of the Sodium-Dependent Multivitamin Transporter to Derivatives of Pantothenic Acid
    2013/05/01 by Srinivas Reddy Chirapu, Charles J. Rotter, Emily Miller +3 · 1 citation
    Biochemistry, Genetics and Molecular Biology · Neuroscience · Chemistry · #Biotin and Related Studies #Neurological diseases and metabolism #Chemical Synthesis and Analysis #Biotin #Transporter #Pantothenic acid #Biochemistry #Chemistry #Vitamin
  20. Expression and Function of Thyroid Hormone Transporters in the Microvillous Plasma Membrane of Human Term Placental Syncytiotrophoblast
    2012/10/19 by L. S. Loubière, LS Loubiere, Elisavet Vasilopoulou +10 · 11 citations
    Chemistry · Medicine · #Biochemistry #Biology #Birth, Development, and Health #Chemistry #Endocrinology #Fetal membrane #Fetus #Hormone #Internal medicine #Medicine #Monocarboxylate transporter #Placenta #Pregnancy #Pregnancy and preeclampsia studies #Solute carrier family #Syncytiotrophoblast #Syncytiotrophoblasts #Thyroid Disorders and Treatments #Transplacental #Transporter
  21. Fruit Juices as Perpetrators of Drug Interactions: The Role of Organic Anion–Transporting Polypeptides
    2012/10/03 by Michael Dolton, M J Dolton, B D Roufogalis +3 · 14 citations
    Chemistry · Medicine · #Antibiotics Pharmacokinetics and Efficacy #Bioavailability #Biochemistry #CYP3A4 #Chemistry #Clinical pharmacology #Cytochrome P450 #Drug #Drug Transport and Resistance Mechanisms #Food science #Fruit juice #Gastroesophageal reflux and treatments #Gene #Grapefruit juice #Medicine #Metabolism #Organic anion-transporting polypeptide #Organic cation transport proteins #Pharmacokinetics #Pharmacology #Transporter
  22. The Physiology of Bicarbonate Transporters in Mammalian Reproduction1
    2012/01/20 by Ying Liu, Dengke Wang, Deng-Ke Wang +2 · 26 citations
    Medicine · Psychology · #Anatomy #Bicarbonate #Biochemistry #Biology #Capacitation #Cell biology #Endocrinology #Epididymis #Genetics #Human fertilization #Intracellular #Intracellular pH #Neuroendocrine regulation and behavior #Nitric Oxide and Endothelin Effects #Oviduct #Pregnancy and preeclampsia studies #Reproduction #Solute carrier family #Sperm #Spermatogenesis #Transporter
  23. Lactate Influx through the Endothelial Cell Monocarboxylate Transporter MCT1 Supports an NF-κB/IL-8 Pathway that Drives Tumor Angiogenesis
    2011/02/08 by Frédérique Végran, Romain Boidot, Carine Michiels +3 · 40 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Angiogenesis #Angiogenesis and VEGF in Cancer #Autocrine signalling #Biochemistry #Biology #Cancer research #Cancer, Hypoxia, and Metabolism #Cell biology #Chemistry #Endothelial stem cell #Glioma Diagnosis and Treatment #Glycolysis #In vitro #Metabolism #Monocarboxylate transporter #Receptor #Transporter #Warburg effect
  24. Flavonoid conjugates interact with organic anion transporters (OATs) and attenuate cytotoxicity of adefovir mediated by organic anion transporter 1 (OAT1/SLC22A6)
    2011/01/18 by Chi Chun Wong, Nigel P. Botting, Caroline Orfila +2 · 19 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · Pharmacology, Toxicology and Pharmaceutics · #Amino Acid Enzymes and Metabolism #Antioxidant #Biochemistry #Biology #Chemistry #Drug Transport and Resistance Mechanisms #Flavonoid #Glucuronidation #Glucuronide #In vitro #Metabolism #Microsome #Organic anion transporter 1 #Pharmacogenetics and Drug Metabolism #Pharmacology #Quercetin #Sulfation #Transporter
  25. The structural basis of secondary active transport mechanisms
    2010/10/27 by Lucy R. Forrest, Reinhard Krämer, Christine Ziegler · 33 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · Neuroscience · #Active transport #Biochemistry #Biology #Biophysics #Catalytic cycle #Chemistry #Conformational change #Context (archaeology) #Enzyme #Ion channel regulation and function #Membrane #Membrane protein #Membrane transport #Membrane transport protein #Neuroscience and Neuropharmacology Research #Protein Structure and Dynamics #Stereochemistry #Substrate (aquarium) #Transmembrane protein #Transport protein #Transporter
  26. Genetic Determinants of Drug-induced Cholestasis and Intrahepatic Cholestasis of Pregnancy
    2010/04/26 by Christiane Pauli‐Magnus, Peter J. Meier, Bruno Stieger · 1 citation
    Medicine · #Bile Salt Export Pump #Bioinformatics #Biology #Cholestasis #Cholestasis of pregnancy #Drug Transport and Resistance Mechanisms #Farnesoid X receptor #Fetus #Gene #Genetics #Internal medicine #Medicine #Nuclear receptor #Pharmacological Effects and Toxicity Studies #Pregnancy #Pregnancy and Medication Impact #Progressive familial intrahepatic cholestasis #Transcription factor #Transporter
  27. Angiotensin II inhibits activity of human organic anion transporter 3 through activation of protein kinase Cα: Accelerating endocytosis of the transporter
    2009/10/29 by Peng Duan, Shanshan Li, Guofeng You · 25 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Angiotensin II #Biochemistry #Biology #Cell #Cell biology #Chemistry #Drug Transport and Resistance Mechanisms #Endocrinology #Endocytosis #Ion Transport and Channel Regulation #Organic anion transporter 1 #Pharmacology #Phosphorylation #Protein kinase C #Receptor #Renin-Angiotensin System Studies #Renin–angiotensin system #Staurosporine #Symporter #Transporter
  28. Cardiolipin and the osmotic stress responses of bacteria
    2009/06/19 by Tatyana Romantsov, Ziqiang Guan, Janet M. Wood · 26 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · #Amino acid #Bacillus subtilis #Bacteria #Bacterial Genetics and Biotechnology #Biochemistry #Biology #Biophysics #Cardiolipin #Chemistry #Escherichia coli #Gene #Ion channel #Lipid Membrane Structure and Behavior #Mechanosensitive channels #Membrane #Osmoprotectant #Osmoregulation #Osmotic concentration #Osmotic pressure #Osmotic shock #Phosphatidic acid #Phosphatidylcholine #Phosphatidylethanolamine #Phosphatidylglycerol #Phospholipid #RNA and protein synthesis mechanisms #Symporter #Transporter
  29. Elevated serum triiodothyronine and intellectual and motor disability with paroxysmal dyskinesia caused by a monocarboxylate transporter 8 gene mutation
    2009/02/19 by Oliver Fuchs, OLIVER FUCHS, NICOLE PFARR +5 · 12 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Biology #Dyskinesia #Endocrinology #Gene #Genetic Syndromes and Imprinting #Genetics #Genetics and Neurodevelopmental Disorders #Hormone #Internal medicine #Medicine #Monocarboxylate transporter #Mutation #Paroxysmal dyskinesia #Thyroid Disorders and Treatments #Transporter #Triiodothyronine
  30. Interplay between the Nuclear Receptor Pregnane X Receptor and the Uptake Transporter Organic Anion Transporter Polypeptide 1A2 Selectively Enhances Estrogen Effects in Breast Cancer
    2008/11/14 by Henriette E. Meyer zu Schwabedissen, Rommel G. Tirona, Cindy S. Yip +3 · 31 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · Pharmacology, Toxicology and Pharmaceutics · #ATP-binding cassette transporter #Biochemistry #Biology #Breast cancer #Cancer #Cancer research #Chromatin immunoprecipitation #Drug Transport and Resistance Mechanisms #Estrogen and related hormone effects #Estrogen receptor #Gene #Gene expression #Genetics #Multidrug resistance-associated protein 2 #Nuclear receptor #Organic anion transporter 1 #Organic anion-transporting polypeptide #Pharmacogenetics and Drug Metabolism #Pharmacology #Pregnane X receptor #Promoter #Solute carrier family #Transcription factor #Transporter

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