Protein kinase C affects the internalization and recycling of organic anion transporting polypeptide 1B1

2015/05/23 by Mei Hong, Weifang Hong, Chunxu Ni +2 · 23 citations
Medicine · Biochemistry, Genetics and Molecular Biology · Pharmacology, Toxicology and Pharmaceutics · #Drug Transport and Resistance Mechanisms #Amino Acid Enzymes and Metabolism #Pharmacogenetics and Drug Metabolism

paper · doi:10.1016/j.bbamem.2015.05.011

Citations

• Fruit juices inhibit organic anion transporting polypeptide–mediated drug uptake to decrease the oral availability of fexofenadine

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• Loss of palmitoylation impacts the interaction between the organic anion transporting polypeptide (OATP) 1B1 and OATP1B3
• An Essential Role of Nedd4-2 in the Ubiquitination, Expression, and Function of Organic Anion Transporter-3. [europepmc]
• Lipopolysaccharide inhibits colonic biotin uptake via interference with membrane expression of its transporter: a role for a casein kinase 2-mediated pathway. [europepmc]
• Protein Kinases C-Mediated Regulations of Drug Transporter Activity, Localization and Expression. [europepmc]
• Regulation of Organic Anion Transporting Polypeptides (OATP) 1B1- and OATP1B3-Mediated Transport: An Updated Review in the Context of OATP-Mediated Drug-Drug Interactions. [europepmc]
• Post-translational modifications of transporters. [europepmc]
• Characterization of Plasma Membrane Localization and Phosphorylation Status of Organic Anion Transporting Polypeptide (OATP) 1B1 c.521 T>C Nonsynonymous Single-Nucleotide Polymorphism. [europepmc]
• OATP1B3 Expression and Function is Modulated by Coexpression with OCT1, OATP1B1, and NTCP. [europepmc]
• The involvement of human organic anion transporting polypeptides (OATPs) in drug-herb/food interactions. [europepmc]
• Post-translational regulation of the major drug transporters in the families of organic anion transporters and organic anion-transporting polypeptides. [europepmc]
• Cell-to-Medium Concentration Ratio Overshoot in the Uptake of Statins by Human Hepatocytes in Suspension, but Not in Monolayer: Kinetic Analysis Suggesting a Partial Loss of Functional OATP1Bs. [europepmc]
• Is It Time to Use Modeling of Cellular Transporter Homeostasis to Inform Drug-Drug Interaction Studies: Theoretical Considerations. [europepmc]
• Pharmacoproteomics of Brain Barrier Transporters and Substrate Design for the Brain Targeted Drug Delivery. [europepmc]
• Regulation of Drug Transport Proteins-From Mechanisms to Clinical Impact: A White Paper on Behalf of the International Transporter Consortium. [europepmc]
• The Double-Leucine Motifs Affect Internalization, Stability, and Function of Organic Anion Transporting Polypeptide 1B1. [europepmc]
• Assessing Trans -Inhibition of OATP1B1 and OATP1B3 by Calcineurin and/or PPIase Inhibitors and Global Identification of OATP1B1/3-Associated Proteins. [europepmc]
• Organic anion transporting polypeptides: Pharmacology, toxicology, structure, and transport mechanisms. [europepmc]
• The Effect of Radixin on the Function and Expression of Organic Anion Transporting Polypeptide 1B1. [europepmc]
• The SLC-ome of membrane transport: From molecular discovery to physiology and clinical applications. [europepmc]
• Altered Bile Acid Transport in Liver Disease. [europepmc]