1. Rhynchophylline as an agonist of sirtuin 3 ameliorates endothelial dysfunction via antagonizing mitochondrial damage of endothelial progenitor cells
   2025/03/31 by Lin Lin, Bowen Sun, Yuanlong Hu +10 · 9 citations
   Biochemistry, Genetics and Molecular Biology · Medicine · #Acetylation #Apoptosis #Biochemistry #Biology #Cancer research #Cell biology #Eicosanoids and Hypertension Pharmacology #Endocrinology #Endothelial dysfunction #Medicinal Plants and Bioactive Compounds #Mitochondrial ROS #Mitochondrion #Oxidative stress #Pharmacology #Progenitor cell #SIRT3 #SOD2 #Sirtuin #Sirtuins and Resveratrol in Medicine #Stem cell #Superoxide dismutase
2. Different stimuli induce endothelial dysfunction and promote atherosclerosis through the Piezo1/YAP signaling axis
   2023/09/14 by Jingying Mao, Ronghao Yang, Ping Yuan +5 · 14 citations
   Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Apoptosis #Autophagy #Biochemistry #Biology #Blood properties and coagulation #Cell biology #Chemistry #Downregulation and upregulation #Endocrinology #Endothelial dysfunction #Endothelial stem cell #Erythrocyte Function and Pathophysiology #Gene #Gene knockdown #Hippo pathway signaling and YAP/TAZ #In vitro #Internal medicine #Ion channel #Medicine #PIEZO1 #Receptor
3. Endothelial mechanobiology in atherosclerosis
   2023/05/10 by Xiaoli Wang, Yang Shen, Min Shang +3 · 27 citations
   Biochemistry, Genetics and Molecular Biology · Medicine · #Angiogenesis and VEGF in Cancer #Biology #Blood flow #Cardiology #Caveolin-1 and cellular processes #Cell biology #Context (archaeology) #Endothelial dysfunction #Endothelium #Homeostasis #Internal medicine #Kruppel-like factors research #Mechanics #Mechanobiology #Mechanotransduction #Medicine #Pathology #Shear stress
4. Low shear stress inhibits endothelial mitophagy via caveolin-1/miR-7-5p/SQSTM1 signaling pathway
   2022/07/31 by Weike Liu, Huajing Song, Jing Xu +7 · 13 citations
   Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Apoptosis #Autophagy #Autophagy in Disease and Therapy #Biochemistry #Biology #Caveolin-1 and cellular processes #Cell biology #Chemistry #Endocrinology #Endothelial dysfunction #Kruppel-like factors research #Mitochondrion #Mitophagy #Oxidative stress #PINK1
5. Amelioration of endothelial dysfunction by sodium glucose co‐transporter 2 inhibitors: pieces of the puzzle explaining their cardiovascular protection
   2022/04/08 by Xiaoling Li, Benedikt Preckel, Jeroen Hermanides +3 · 13 citations
   Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Advanced Glycation End Products research #Angiogenesis #Biochemistry #Chemistry #Diabetes Treatment and Management #Diabetes mellitus #Endocrinology #Endothelial dysfunction #Endothelium #Enzyme #Internal medicine #Medicine #Nicotinamide adenine dinucleotide phosphate #Nitric Oxide and Endothelin Effects #Oxidative stress #Pharmacology #Vasodilation
6. Endothelial Dysfunction in Covid-19 Infection
   2022/01/31 by Hassan M. Otifi, Balkur Krishna Moorthy Adiga, Balkur K. Adiga · 25 citations
   Biochemistry, Genetics and Molecular Biology · Medicine · #ARDS #Bioinformatics #COVID-19 Clinical Research Studies #Coronavirus disease 2019 (COVID-19) #Disease #Endothelial dysfunction #Endothelium #Heme Oxygenase-1 and Carbon Monoxide #Immunology #Infectious disease (medical specialty) #Intensive care medicine #Internal medicine #Long-Term Effects of COVID-19 #Lung #Medicine #Pathogenesis #Pathology #Pathophysiology
7. Reversal of emphysema by restoration of pulmonary endothelial cells
   2021/07/21 by Shu Hisata, Alexandra C. Racanelli, Pouneh Kermani +19 · 27 citations
   Immunology and Microbiology · Medicine · #Airway #Airway obstruction #Biology #Biomarkers in Disease Mechanisms #COPD #Cardiology #Chronic Obstructive Pulmonary Disease (COPD) Research #Clusterin in disease pathology #Endothelial dysfunction #Endothelial stem cell #Endothelium #Immunology #Inflammation #Internal medicine #Lung #Lung volume reduction surgery #Lung volumes #Medicine #Pathogenesis #Pathology #Surgery
8. Eye bank versus surgeon prepared DMEK tissues: influence on adhesion and re-bubbling rate
   2020/10/30 by Vito Romano, Ahmed Kazaili, Luca Pagano +18 · 11 citations
   Medicine · #Adhesion #Cardiology #Cataract surgery #Cornea #Corneal Surgery and Treatments #Corneal surgery and disorders #Descemet membrane #Endothelial dysfunction #Endothelium #Eye bank #Internal medicine #Materials science #Medicine #Ophthalmology #Retinal and Macular Surgery #Surgery #Tamponade
9. Obesity, Hypertension, and Cardiac Dysfunction
   2020/03/12 by Alan J. Mouton, Xuan Li, Michael E. Hall +1 · 29 citations
   Medicine · #Apelin-related biomedical research #Cardiac dysfunction #Cardiology #Cardiovascular Function and Risk Factors #Endothelial dysfunction #Heart failure #Hormonal Regulation and Hypertension #Internal medicine #Medicine #Obesity
10. MicroRNA-200a improves diabetic endothelial dysfunction by targeting KEAP1/NRF2
    2020/02/07 by Ziping Jiang, Junduo Wu, Fuzhe Ma +8 · 15 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Apoptosis #Biochemistry #Biology #Cardiovascular, Neuropeptides, and Oxidative Stress Research #Cell biology #Chemistry #Diabetes mellitus #Endocrinology #Endothelial dysfunction #Gene knockdown #Genomics, phytochemicals, and oxidative stress #Inflammation #Internal medicine #KEAP1 #Medicine #MicroRNA in disease regulation #Oxidative stress #Pharmacology #Regulator #Signal transduction #Transcription factor #microRNA
11. ESC Working Group on Coronary Pathophysiology and Microcirculation position paper on ‘coronary microvascular dysfunction in cardiovascular disease’
    2020/02/05 by Teresa Padro, Teresa Padró, Olivia Manfrini +18 · 27 citations
    Medicine · #Acute Myocardial Infarction Research #Blood flow #Cardiac Imaging and Diagnostics #Cardiology #Cardiovascular Disease and Adiposity #Coronary circulation #Coronary disease #Coronary heart disease #Disease #Endothelial dysfunction #Internal medicine #Medicine #Microcirculation #Pathophysiology
12. Oxidative stress in pregnancy complicated by preeclampsia
    2020/01/05 by Sindy San Juan-Reyes, Leobardo Manuel Gómez-Oliván, Leobardo Manuel Gómez‐Oliván +4 · 25 citations
    Medicine · #Biochemistry #Bioinformatics #Biology #Birth, Development, and Health #Cell biology #Endothelial dysfunction #Enzyme #Fetus #Genetics #Gestational Diabetes Research and Management #Immune system #Immunology #Internal medicine #Medicine #Mitochondrion #NADPH oxidase #Oxidative stress #Pathophysiology #Placenta #Preeclampsia #Pregnancy #Pregnancy and preeclampsia studies #Reactive oxygen species #Xanthine oxidase
13. Red blood cell dysfunction: a new player in cardiovascular disease
    2019/06/10 by John Pernow, Ali Mahdi, Jiangning Yang +1 · 26 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Biology #Cell biology #Diabetes mellitus #Disease #Endocrinology #Endothelial dysfunction #Endothelium #Erythrocyte Function and Pathophysiology #Hemoglobin structure and function #Internal medicine #Ischemia #Medicine #Neonatal Health and Biochemistry #Nitric oxide #Oxidative stress #Pharmacology #Reactive oxygen species #Red blood cell
14. Oxidative Stress Contributes to Microvascular Endothelial Dysfunction in Men and Women With Major Depressive Disorder
    2019/01/17 by Jody L. Greaney, Erika F.H. Saunders, Lakshmi Santhanam +1 · 26 citations
    Chemistry · Medicine · Neuroscience · #Apocynin #Biochemistry #Chemistry #Endocrinology #Endothelial dysfunction #Endothelium #Internal medicine #Major depressive disorder #Medicine #NADPH oxidase #Nitric Oxide and Endothelin Effects #Oxidative stress #Stress Responses and Cortisol #Superoxide #Tryptophan and brain disorders #Vasodilation
15. TRAF6 mediates high glucose-induced endothelial dysfunction
    2018/07/12 by Rong Liu, Hong Shen, Tao Wang +6 · 10 citations
    Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · Medicine · #Apoptosis #Atherosclerosis and Cardiovascular Diseases #Biochemistry #Biology #Cell #Cell Adhesion Molecules Research #Cell adhesion #Cell adhesion molecule #Cell biology #Diabetes mellitus #Downregulation and upregulation #Endocrinology #Endothelial dysfunction #Endothelial stem cell #Gene knockdown #ICAM-1 #Immunology #In vitro #Intercellular Adhesion Molecule-1 #Molecular biology #NF-κB Signaling Pathways #Streptozotocin #Tumor necrosis factor alpha #Viability assay
16. Hyperuricemia enhances intracellular urate accumulation via down-regulation of cell-surface BCRP/ABCG2 expression in vascular endothelial cells
    2018/01/06 by Hisakazu Komori, Kazuyuki Yamada, Ikumi Tamai · 25 citations
    Chemistry · Medicine · #ATP-binding cassette transporter #Abcg2 #Alcohol Consumption and Health Effects #Biochemistry #Biology #Bone and Joint Diseases #Chemistry #Endocrinology #Endothelial dysfunction #Gout, Hyperuricemia, Uric Acid #Hyperuricemia #Internal medicine #Medicine #NADPH oxidase #Oxidative stress #Transporter #Uric acid
17. Roles of Vascular Oxidative Stress and Nitric Oxide in the Pathogenesis of Atherosclerosis
    2017/02/16 by Ulrich Förstermann, Ning Xia, Huige Li · 41 citations
    Chemistry · Immunology and Microbiology · Medicine · #Biochemistry #Biology #Cardiovascular, Neuropeptides, and Oxidative Stress Research #Chemistry #Diabetes mellitus #Endocrinology #Endothelial dysfunction #Endothelium #Enzyme #Internal medicine #Medicine #NADPH oxidase #Neutrophil, Myeloperoxidase and Oxidative Mechanisms #Nicotinamide adenine dinucleotide phosphate #Nitric Oxide and Endothelin Effects #Nitric oxide #Oxidase test #Oxidative stress #Reactive nitrogen species #Reactive oxygen species #Xanthine oxidase
18. Thirty Years of Saying NO
    2016/07/07 by Paul M. Vanhoutte, Yingzi Zhao, Aimin Xu +1 · 26 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Biochemistry #Biology #Bradykinin #Chemistry #Eicosanoids and Hypertension Pharmacology #Endocrinology #Endothelial dysfunction #Endothelial stem cell #Endothelium #Hormonal Regulation and Hypertension #Internal medicine #Medicine #Nitric Oxide and Endothelin Effects #Nitric oxide #Nitric oxide synthase #Receptor #Soluble guanylyl cyclase #Tetrahydrobiopterin #Vascular smooth muscle
19. Endothelium-Derived 5-Methoxytryptophan Is a Circulating Anti-Inflammatory Molecule That Blocks Systemic Inflammation
    2016/05/06 by Yi‐Fu Wang, Yi-Fu Wang, Yu‐Juei Hsu +10 · 25 citations
    Chemistry · Immunology and Microbiology · Medicine · #Biochemistry #Chemistry #Endogeny #Endothelial activation #Endothelial dysfunction #Endothelial stem cell #Endothelium #Immune cells in cancer #Immunology #Inflammation #Internal medicine #Lipopolysaccharide #Medicine #Neutrophil, Myeloperoxidase and Oxidative Mechanisms #Nitric Oxide and Endothelin Effects #Pharmacology #Proinflammatory cytokine #Sepsis #Systemic inflammation #Tumor necrosis factor alpha
20. Erectile dysfunction in chronic kidney disease: From pathophysiology to management
    2015/01/01 by Eirini Papadopoulou · 1 citation
    Medicine · #Diabetes mellitus #Disease #Endocrinology #Endothelial dysfunction #Environmental health #Erectile dysfunction #Hormonal and reproductive studies #Incidence (geometry) #Intensive care medicine #Internal medicine #Kidney disease #Life expectancy #Medicine #Pathophysiology #Population #Quality of life (healthcare) #Sexual dysfunction #Sexual function #Sexual function and dysfunction studies #Urinary Bladder and Prostate Research
21. Pulmonary Arterial Hypertension
    2014/06/20 by Yen‐Chun Lai, Yen-Chun Lai, Karin C. Potoka +3 · 27 citations
    Medicine · #Blood pressure #Cardiology #Cardiovascular Issues in Pregnancy #Endothelial dysfunction #Heart failure #Hemodynamics #Internal medicine #Medicine #Nitric oxide #Pathogenesis #Pathophysiology #Pathophysiology of hypertension #Prostacyclin #Pulmonary Hypertension Research and Treatments #Pulmonary artery #Pulmonary hypertension #Pulmonary vasculature #Renin-Angiotensin System Studies #Vascular resistance
22. High-density lipoproteins as modulators of endothelial cell functions: alterations in patients with coronary artery disease
    2014/06/15 by A. Kratzer, Adelheid Kratzer, Héctor Giral +3 · 25 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Biochemistry #Biology #Cholesterol #Coronary artery disease #Diabetes, Cardiovascular Risks, and Lipoproteins #Endocrinology #Endothelial dysfunction #Endothelial stem cell #Endothelium #High-density lipoprotein #Homeostasis #Inflammation #Internal medicine #Lipid metabolism and disorders #Lipoprotein #Medicine #Nitric oxide #Paraoxonase enzyme and polymorphisms
23. Omega-3 PUFAs improved endothelial function and arterial stiffness with a parallel antiinflammatory effect in adults with metabolic syndrome
    2013/10/25 by Dimitris Tousoulis, Aris Plastiras, Gerasimos Siasos +9 · 26 citations
    Chemistry · Medicine · Nursing · #Arterial stiffness #Biochemistry #Biology #Blood pressure #Cardiology #Cardiovascular Disease and Adiposity #Cardiovascular Health and Disease Prevention #Cell biology #Chemistry #Endothelial dysfunction #Fatty Acid Research and Health #Fatty acid #Function (biology) #Internal medicine #Medicine #Metabolic syndrome #Obesity #Polyunsaturated fatty acid
24. Cardiac Syndrome X and Microvascular Coronary Dysfunction
    2012/08/01 by Erika Jones, Wafia Eteiba, C. Noel Bairey Merz +1 · 1 citation
    Medicine · #Acute Myocardial Infarction Research #Angina #Cardiac Imaging and Diagnostics #Cardiac dysfunction #Cardiac syndrome X #Cardiology #Cardiovascular Issues in Pregnancy #Chest pain #Endothelial dysfunction #Heart failure #Internal medicine #Ischemia #Medicine #Myocardial infarction #Myocardial ischemia
25. Aldosterone Inactivates the Endothelin-B Receptor via a Cysteinyl Thiol Redox Switch to Decrease Pulmonary Endothelial Nitric Oxide Levels and Modulate Pulmonary Arterial Hypertension
    2012/07/12 by Bradley A. Maron, Ying-Yi Zhang, Yingyi Zhang +7 · 27 citations
    Medicine · #Aldosterone #Endocrinology #Endothelial dysfunction #Endothelin 1 #Endothelin receptor #Enos #Hormonal Regulation and Hypertension #Internal medicine #Medicine #Mineralocorticoid receptor #Nitric Oxide and Endothelin Effects #Nitric oxide #Nitric oxide synthase #Pulmonary Hypertension Research and Treatments #Receptor #Spironolactone
26. The Role of Nitric Oxide on Endothelial Function
    2011/12/26 by Dimitris Tousoulis, Anna–Maria Kampoli, Costas Tentolouris Nikolaos Papageorgiou +1 · 1 citation
    Medicine · Biochemistry, Genetics and Molecular Biology · #Nitric Oxide and Endothelin Effects #Eicosanoids and Hypertension Pharmacology #Nitric oxide #Endothelium #Medicine #Endothelial dysfunction #Nitric oxide synthase #Endothelial stem cell #Vasodilation #Internal medicine #Endocrinology #Pharmacology #Biochemistry #Biology #In vitro
27. Inhibition of matrix metalloproteinase‐2 improves endothelial function and prevents hypertension in insulin‐resistant rats
    2011/07/14 by PR Nagareddy, PS Rajput, H Vasudevan +9 · 15 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Adipokines, Inflammation, and Metabolic Diseases #Biochemistry #Biology #Cell biology #Endocrinology #Endothelial dysfunction #Enos #Extracellular matrix #Heat shock protein #Hsp90 #Insulin #Insulin resistance #Internal medicine #Matrix metalloproteinase #Medicine #Nitric Oxide and Endothelin Effects #Nitric oxide #Nitric oxide synthase #Protease and Inhibitor Mechanisms #Vascular endothelial growth factor #Vascular endothelial growth factor A #Vascular endothelial growth factor B
28. Obesity, the Metabolic Syndrome, and Sexual Dysfunction in Men
    2011/05/25 by Katherine Esposito, K Esposito, Dario Giugliano +1 · 8 citations
    Medicine · #Clinical pharmacology #Endocrinology #Endothelial dysfunction #Erectile dysfunction #Hormonal and reproductive studies #Inflammation #Internal medicine #Medicine #Metabolic syndrome #Nitric oxide #Obesity #Pharmacology #Pharmacology and Obesity Treatment #Proinflammatory cytokine #Sexual dysfunction #Sexual function and dysfunction studies #Testosterone (patch)
29. Oxidized LDL, a critical factor in atherogenesis☆
    2005/11/06 by D LI, Dong Li, J. L. Mehta +1 · 25 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · Immunology and Microbiology · Medicine · #ABCA1 #Atherosclerosis and Cardiovascular Diseases #Biochemistry #Biology #Cancer, Lipids, and Metabolism #Chemistry #Cholesterol #Cholesterol and Lipid Metabolism #Endocrinology #Endothelial dysfunction #Internal medicine #LDL receptor #Lipoprotein #Liver X receptor #Medicine #Nuclear receptor #Oxysterol #Pathogenesis #Reverse cholesterol transport #Transcription factor #Transporter
30. Secondhand smoke as an acute threat for the cardiovascular system: a change in paradigm
    2005/10/17 by Tobias Raupach, Katrin Schäfer, Stavros Konstantinides +1 · 1 citation
    Medicine · #Adipokines, Inflammation, and Metabolic Diseases #Adipose Tissue and Metabolism #Cardiology #Cardiovascular Disease and Adiposity #Disease #Endothelial dysfunction #Endothelium #Inflammation #Internal medicine #Medicine #Nitric oxide #Oxidative stress #Passive smoking #Pathology #Pathophysiology #Thrombus

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