- Rhynchophylline as an agonist of sirtuin 3 ameliorates endothelial dysfunction via antagonizing mitochondrial damage of endothelial progenitor cells
2025/03/31 by Lin Lin, Bowen Sun, Yuanlong Hu +10 · 9 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Acetylation #Apoptosis #Biochemistry #Biology #Cancer research #Cell biology #Eicosanoids and Hypertension Pharmacology #Endocrinology #Endothelial dysfunction #Medicinal Plants and Bioactive Compounds #Mitochondrial ROS #Mitochondrion #Oxidative stress #Pharmacology #Progenitor cell #SIRT3 #SOD2 #Sirtuin #Sirtuins and Resveratrol in Medicine #Stem cell #Superoxide dismutase
- Inhibition of myocardial reperfusion injury by ischemic postconditioning requires sirtuin 3-mediated deacetylation of cyclophilin D
2015/04/11 by Thomas Bochaton, T. Bochaton, C. Crola-Da-Silva +16 · 26 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Acetylation #Biochemistry #Biology #Cardiac Ischemia and Reperfusion #Cardiology #Chemistry #Cyclophilin A #Downregulation and upregulation #Internal medicine #Ischemia #Medicine #Molecular biology #Myocardial ischemia #Pharmacology #Reperfusion injury #Signaling Pathways in Disease #Sirtuin #Sirtuin 1 #Sirtuins and Resveratrol in Medicine
- Calorie restriction attenuates cerebral ischemic injury via increasing SIRT1 synthesis in the rat
2015/04/06 by Mingzi Ran, Zhaoju Li, Lujia Yang +5 · 25 citations
Medicine · #Adipose Tissue and Metabolism #Anesthesia #Apoptosis #Biochemical effects in animals #Biochemistry #Biology #Calorie #Calorie restriction #Downregulation and upregulation #Endocrinology #Enzyme #Gene knockdown #In vivo #Internal medicine #Ischemia #Medicine #Middle cerebral artery #Neuroprotection #Sirtuin #Sirtuin 1 #Sirtuins and Resveratrol in Medicine
- Structural and Functional Analysis of Human SIRT1
2013/10/10 by Andrew M. Davenport, Ferdinand M. Huber, Ferdinand Huber +1 · 28 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Immunology and Microbiology · Medicine · #Binding site #Biochemistry #Biology #Biophysics #Calcium signaling and nucleotide metabolism #Chemistry #Cofactor #Enzyme #Gene #NAD+ kinase #Plasma protein binding #Protein structure #Sirtuin #Sirtuin 1 #Sirtuins and Resveratrol in Medicine #Stereochemistry #Toxin Mechanisms and Immunotoxins
- Disruption of the Ang II type 1 receptor promotes longevity in mice
2009/02/06 by Ariela Benigni, Daniela Corna, Carla Zoja +10 · 2 citations
Medicine · Neuroscience · #Adipose Tissue and Metabolism #Dietary Effects on Health #Neuroinflammation and Neurodegeneration Mechanisms #SIRT3 #Angiotensin II #Angiotensin II receptor type 1 #Biology #Endocrinology #Internal medicine #Downregulation and upregulation #Receptor #Renin–angiotensin system #Oxidative stress #Longevity #Inflammation #Sirtuin #Cell biology #Immunology #Medicine #Gene