1. Coumarins link iron deficiency to TOR inhibition in plants
   2026/07/01 by Huikyong Cho, Ilyeong Choi, Sachi Horibata +7 · 2 voices
   Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · #Arabidopsis #Arabidopsis thaliana #Coumarin #Endogeny #Kinase #Metabolism #Nitrogen and Sulfur Effects on Brassica #PI3K/AKT/mTOR signaling in cancer #Plant nutrient uptake and metabolism #Regulator #Second messenger system #Signal transduction #TOR signaling
2. Neural crest induction requires SALL4-mediated BAF recruitment to lineage specific enhancers
   2025/11/28 by Martina Demurtas, Samantha M. Barnada, Emma van Domselaar +3 · 2 voices · 1 citation
   Biochemistry, Genetics and Molecular Biology · #Cranial neural crest #Developmental Biology and Gene Regulation #Enhancer #Neural crest #Neural development #Neural fold #Neural plate #Pluripotent Stem Cells Research #Regulator #Renal and related cancers #Transcription factor
3. A "good regulator theorem" for embodied agents
   2025/08/04 by Nathaniel Virgo, Virgo, Nathaniel, Martin Biehl +5 · 4 citations
   Computer Science · Neuroscience · Psychology · #Artificial Intelligence (cs.AI) #Computability, Logic, AI Algorithms #Counterexample #Embodied and Extended Cognition #Embodied cognition #FOS: Computer and information sciences #FOS: Electrical engineering #Intuition #Observer (physics) #Philosophy and Theoretical Science #Property (philosophy) #Regulator #Systems and Control (eess.SY) #electronic engineering #information engineering
4. Intracellular ATP concentration is a key regulator of bacterial cell fate
   2024/11/12 by Bo Li, Xiao Chen, Jin-Yu Yang +3 · 9 citations
   Biochemistry, Genetics and Molecular Biology · #Bacteria #Bacterial Genetics and Biotechnology #Biochemistry #Biology #Cell biology #Ecology #Escherichia coli research studies #Genetics #Intracellular #Key (lock) #Regulator #Vibrio bacteria research studies
5. Lactylation stabilizes TFEB to elevate autophagy and lysosomal activity
   2024/04/04 by Yewei Huang, Gan Luo, Kesong Peng +13 · 25 citations
   Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Autophagy #Autophagy in Disease and Therapy #Basic helix-loop-helix leucine zipper transcription factors #Biochemistry #Biogenesis #Biology #Cell biology #Cellular transport and secretion #Chemistry #DNA-binding protein #Enzyme #Gene #Lysosome #Proteasome #Regulator #TFEB #Transcription factor #Ubiquitin #Ubiquitin and proteasome pathways #Ubiquitin ligase #Ubiquitin-Protein Ligases
6. Exercise-induced circular RNA circUtrn is required for cardiac physiological hypertrophy and prevents myocardial ischaemia–reperfusion injury
   2023/10/28 by Lijun Wang, Jingyi Feng, Feng Xing +14 · 20 citations
   Biochemistry, Genetics and Molecular Biology · Medicine · #Biochemistry #Biology #Cardiology #Circular RNAs in diseases #Downregulation and upregulation #Endocrinology #GDF15 and Related Biomarkers #Gene #Internal medicine #Ischemia #Medicine #Muscle Physiology and Disorders #Muscle hypertrophy #Regulator #Reperfusion injury
7. The role of TXNIP in cancer: a fine balance between redox, metabolic, and immunological tumor control
   2023/10/04 by Jinhai Deng, Teng Pan, Zaoqu Liu +9 · 25 citations
   Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Biochemistry #Biology #Cancer #Cancer research #Cell biology #Gene #Genetics #Glutathione Transferases and Polymorphisms #Immunology #Inflammation #Medicine #Metal-Catalyzed Oxygenation Mechanisms #Oxidative stress #Redox biology and oxidative stress #Regulator #TXNIP #Thioredoxin #Thioredoxin-Interacting Protein #Tumor cells #Tumor microenvironment
8. Prdm16 is a critical regulator of adult long-term hematopoietic stem cell quiescence
   2020/12/02 by Kristbjorn O. Gudmundsson, Nhu Nguyen, Kevin Oakley +7 · 12 citations
   Immunology and Microbiology · Medicine · #Biology #Cancer research #Cell biology #Cell cycle #Conditional gene knockout #Gene #Gene expression #Genetics #Haematopoiesis #Hematopoietic Stem Cell Transplantation #Hematopoietic stem cell #Immune Cell Function and Interaction #PRDM16 #Phenotype #Regulator #Stem cell #T-cell and B-cell Immunology #Transcription factor
9. Abl and Canoe/Afadin mediate mechanotransduction at tricellular junctions
   2020/11/26 by Huapeng H. Yu, Jennifer A. Zallen · 1 voice · 33 citations
   Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · Chemistry · Materials Science · #ABL #Adherens junction #Adhesion #Biology #Cadherin #Cell #Cell biology #Cellular Mechanics and Interactions #Chemistry #Gene #Genetics #Mechanotransduction #Phosphorylation #Plant Surface Properties and Treatments #Regulator #Signal transduction #Silk-based biomaterials and applications #Tight junction #Tyrosine kinase
10. RSK3 mediates necroptosis by regulating phosphorylation of RIP3 in rat retinal ganglion cells
    2020/03/12 by Mi Wang, Hao Wan, Shuchao Wang +11 · 23 citations
    Biochemistry, Genetics and Molecular Biology · #Apoptosis #Biochemistry #Biology #Cell biology #Cell death mechanisms and regulation #Hippo pathway signaling and YAP/TAZ #Kinase #Mitochondrial Function and Pathology #Necroptosis #Phosphorylation #Programmed cell death #Regulator #Retinal #Retinal ganglion cell
11. MicroRNA-200a improves diabetic endothelial dysfunction by targeting KEAP1/NRF2
    2020/02/07 by Ziping Jiang, Junduo Wu, Fuzhe Ma +8 · 15 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Apoptosis #Biochemistry #Biology #Cardiovascular, Neuropeptides, and Oxidative Stress Research #Cell biology #Chemistry #Diabetes mellitus #Endocrinology #Endothelial dysfunction #Gene knockdown #Genomics, phytochemicals, and oxidative stress #Inflammation #Internal medicine #KEAP1 #Medicine #MicroRNA in disease regulation #Oxidative stress #Pharmacology #Regulator #Signal transduction #Transcription factor #microRNA
12. Discovery of anti-mucoviscous activity of rifampicin and its potential as a candidate antivirulence agent against hypervirulent Klebsiella pneumoniae
    2019/06/04 by Hiroki Namikawa, Ken-Ichi Oinuma, Arata Sakiyama +9 · 13 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Antibiotic Resistance in Bacteria #Antibiotics #Antimicrobial #Biology #Escherichia coli #Gene #Genetics #Klebsiella pneumoniae #Microbiology #Phenotype #Pneumocystis jirovecii pneumonia detection and treatment #Pneumonia and Respiratory Infections #Regulator #Rifampicin #Virulence
13. The extracellular matrix as a key regulator of intracellular signalling networks
    2018/03/06 by Jordan F Hastings, Jordan F. Hastings, Joanna N. Skhinas +6 · 30 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Biochemistry #Biology #Cell Adhesion Molecules Research #Cell biology #Cellular Mechanics and Interactions #Chemistry #Computational biology #Ecology #Extracellular matrix #Intracellular #Key (lock) #Regulator #Signaling Pathways in Disease #Signalling
14. Preferential intracellular pH regulation: hypotheses and perspectives
    2016/08/01 by Ryan B. Shartau, Daniel W. Baker, D. W. Baker +2 · 7 citations
    Earth and Planetary Sciences · Environmental Science · #Amphibian #Biochemistry #Biology #Cell biology #Ecology #Extracellular #Fish Ecology and Management Studies #Gene #Homeostasis #Intracellular #Intracellular pH #Ocean Acidification Effects and Responses #Ocean acidification #Physiological and biochemical adaptations #Regulator #Vertebrate
15. FOXC1 maintains the hair follicle stem cell niche and governs stem cell quiescence to preserve long-term tissue-regenerating potential
    2016/02/24 by Kenneth Lay, Tsutomu Kume, Elaine Fuchs · 29 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Biology #Cancer and Skin Lesions #Cell biology #Ecology #Genetics #Hair Growth and Disorders #Hair follicle #Niche #Progenitor cell #Regeneration (biology) #Regulator #Stem cell #Stem cell niche #Wnt/β-catenin signaling in development and cancer
16. Emerging role of PLAG1 as a regulator of growth and reproduction
    2015/11/17 by Almas R Juma, Pauliina Damdimopoulou, Pauliina E Damdimopoulou +5 · 25 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Biology #Carcinogenesis #Endocrinology #Gene #Genetic Syndromes and Imprinting #Genetics #Genomics and Chromatin Dynamics #Hedgehog Signaling Pathway Studies #Internal medicine #Medicine #Phenotype #Regulator
17. The R-spondin/Lgr5/Rnf43 module: regulator of Wnt signal strength
    2014/02/14 by Wim de Lau, Weng Chuan Peng, Piet Gros +1 · 3 citations
    Biochemistry, Genetics and Molecular Biology · #Biology #Cancer research #Cancer-related gene regulation #Cell biology #Enhancer #Gene #Gene expression #Genetics #LGR5 #LRP6 #Polyamine Metabolism and Applications #Regulator #Signal transduction #Stem cell #Wnt signaling pathway #Wnt/β-catenin signaling in development and cancer
18. Differential roles of proteasome and immunoproteasome regulators Pa28αβ, Pa28γ and Pa200 in the degradation of oxidized proteins
    2012/05/01 by Andrew M. Pickering, Kelvin J.A. Davies · 26 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · #Biochemistry #Biology #Cell biology #Cellular adaptation #Chemistry #Cytoplasm #DNA Repair Mechanisms #Endoplasmic Reticulum Stress and Disease #Gene #Oxidative stress #Proteasome #Regulator #Ubiquitin #Ubiquitin and proteasome pathways
19. PR-domain–containing Mds1-Evi1 is critical for long-term hematopoietic stem cell function
    2011/06/11 by Yi Zhang, Sandra Stehling-Sun, Kimberly Lezon-Geyda +7 · 25 citations
    Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · Medicine · #Acute Myeloid Leukemia Research #Biology #Cancer research #Cell biology #Cell cycle #Epigenetics and DNA Methylation #Gene #Gene silencing #Genetics #Haematopoiesis #Hematopoietic stem cell #Immune Cell Function and Interaction #Regulator #Stem cell
20. IL‐6: Regulator of Treg/Th17 balance
    2010/06/25 by Akihiro Kimura, Tadamitsu Kishimoto · 35 citations
    Immunology and Microbiology · Medicine · #Biology #Cytokine #Dermatology and Skin Diseases #Effector #Gene #IL-2 receptor #Immune system #Immunity #Immunology #Interleukin 10 #Interleukin 17 #Psoriasis: Treatment and Pathogenesis #Regulator #Regulatory B cells #Regulatory T cell #T cell #T-cell and B-cell Immunology #Treg cell
21. TNF-α/NF-κB/Snail pathway in cancer cell migration and invasion
    2010/01/19 by Y Wu, Yadi Wu, Binhua P. Zhou +1 · 34 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Angiogenesis #Biology #Cancer #Cancer cell #Cancer research #Cell #Cell migration #Cytokine Signaling Pathways and Interactions #Immunology #Inflammation #Inflammatory mediators and NSAID effects #Internal medicine #Medicine #Metastasis #NF-κB Signaling Pathways #Regulator #Tumor necrosis factor alpha
22. mTOR regulation of autophagy
    2010/01/18 by Chang Hwa Jung, Seung‐Hyun Ro, Seung-Hyun Ro +5 · 37 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Apoptosis #Autophagy #Autophagy in Disease and Therapy #Autophagy-related protein 13 #BAG3 #Biochemistry #Biology #Cell biology #Cell growth #Gene #Kinase #Master regulator #Mechanistic target of rapamycin #PI3K/AKT/mTOR pathway #PI3K/AKT/mTOR signaling in cancer #Polyamine Metabolism and Applications #Protein kinase A #Protein phosphorylation #RPTOR #Regulator #Signal transduction #TOR signaling #Transcription factor #ULK1
23. An RNA code for the FOX2 splicing regulator revealed by mapping RNA-protein interactions in stem cells
    2009/01/11 by Gene W Yeo, G Yeo, Nicole G Coufal +8 · 2 citations
    Biochemistry, Genetics and Molecular Biology · #Alternative splicing #Biology #Cell biology #Computational biology #Embryonic stem cell #Exon #Exonic splicing enhancer #Gene #Genetics #Minigene #RNA #RNA Research and Splicing #RNA and protein synthesis mechanisms #RNA modifications and cancer #RNA splicing #RNA-binding protein #Regulator #Splicing factor
24. Mechanical feedback as a possible regulator of tissue growth
    2005/02/22 by Boris I. Shraiman · 2 citations
    Biochemistry, Genetics and Molecular Biology · Agricultural and Biological Sciences · #Cellular Mechanics and Interactions #Biocrusts and Microbial Ecology #Hippo pathway signaling and YAP/TAZ #Imaginal disc #Context (archaeology) #Mechanism (biology) #Cell division #Cell growth #Cell biology #Biology #Morphogenesis #Regulator #Cell #Drosophila melanogaster #Genetics #Physics
25. Involvement of a Chaperone Regulator, Bcl2-associated Athanogene-4, in Apolipoprotein B mRNA Editing
    2003/12/01 by Paul P. Lau, Lawrence Chan · 1 citation
    Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Heat shock proteins research #RNA Research and Splicing #RNA and protein synthesis mechanisms #Regulator #Chaperone (clinical) #Master regulator #Messenger RNA #Apolipoprotein B #Cell biology #Chemistry #Biology #Biochemistry #Medicine #Gene #Transcription factor
26. The Nuclear Pregnane X Receptor: A Key Regulator of Xenobiotic Metabolism
    2002/10/01 by Steven A. Kliewer, Bryan Goodwin, Timothy M. Willson · 1 citation
    Pharmacology, Toxicology and Pharmaceutics · Biochemistry, Genetics and Molecular Biology · Medicine · Chemistry · #Pharmacogenetics and Drug Metabolism #Estrogen and related hormone effects #Drug Transport and Resistance Mechanisms #Pregnane X receptor #Nuclear receptor #Xenobiotic #Constitutive androstane receptor #CYP3A4 #Drug metabolism #Pregnane #Chemistry #Biochemistry #Receptor #Ligand (biochemistry) #Pharmacology #Cytochrome P450 #Regulator #Biology #Metabolism #Gene #Transcription factor #Stereochemistry #Enzyme
27. Pax genes and eye organogenesis
    2002/08/01 by Franck Pichaud, Claude Desplan · 2 citations
    Biochemistry, Genetics and Molecular Biology · #Biology #Developmental Biology and Gene Regulation #Evolutionary biology #Eye development #Gene #Genetics #Hedgehog Signaling Pathway Studies #Organogenesis #PAX6 #Regulator #Retinal Development and Disorders #Transcription factor
28. Tight regulation, modulation, and high-level expression by vectors containing the arabinose PBAD promoter
    1995/07/01 by L M Guzman, Luz‐Maria Guzman, Dominique Belin +5 · 58 citations
    Biochemistry, Genetics and Molecular Biology · Environmental Science · #Arabinose #Bacterial Genetics and Biotechnology #Bacteriophages and microbial interactions #Biochemistry #Biology #Cell biology #Computational biology #Expression vector #Gene #Gene expression #Genetics #Inducer #Mutant #Operon #Plasmid #Psychological repression #RNA and protein synthesis mechanisms #Recombinant DNA #Regulation of gene expression #Regulator #Repressor #Vector (molecular biology)
29. Apoptosis (the 1992 Frank Rose Memorial Lecture)
    1993/02/01 by AH Wyllie · 12 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Apoptosis #Biology #Cancer Research and Treatments #Cancer research #Cancer-related Molecular Pathways #Carcinogenesis #Cell biology #Cell cycle #Cell death mechanisms and regulation #Cell growth #Gene #Gene expression #Genetics #Medicine #Population #Programmed cell death #Regulation of gene expression #Regulator
30. SEQUENCES, SEQUENCES, AND SEQUENCES
    1988/06/01 by Frederick Sanger · 2 citations
    Biochemistry, Genetics and Molecular Biology · #Hippo pathway signaling and YAP/TAZ #Drosophila melanogaster #Regulator #Biology #Cell fate determination #Hippo signaling pathway #Computational biology #Melanogaster #Evolutionary biology #Key (lock) #Cell biology #Signal transduction #Genetics #Transcription factor #Gene #Ecology

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