- mTOR regulation of autophagy
2010/01/18 by Chang Hwa Jung, Seung‐Hyun Ro, Seung-Hyun Ro +5 · 37 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Apoptosis #Autophagy #Autophagy in Disease and Therapy #Autophagy-related protein 13 #BAG3 #Biochemistry #Biology #Cell biology #Cell growth #Gene #Kinase #Master regulator #Mechanistic target of rapamycin #PI3K/AKT/mTOR pathway #PI3K/AKT/mTOR signaling in cancer #Polyamine Metabolism and Applications #Protein kinase A #Protein phosphorylation #RPTOR #Regulator #Signal transduction #TOR signaling #Transcription factor #ULK1
- Trehalose, a Novel mTOR-independent Autophagy Enhancer, Accelerates the Clearance of Mutant Huntingtin and α-Synuclein
2006/12/21 by Sovan Sarkar, J. Eric Davies, Janet E. Davies +3 · 35 citations
Chemistry · Medicine · Neuroscience · #Activator (genetics) #Alpha-synuclein #Apoptosis #Autophagy #Autophagy in Disease and Therapy #BAG3 #Biochemistry #Biology #Cell biology #Chemical chaperone #Chemistry #Genetic Neurodegenerative Diseases #Huntingtin #Huntingtin Protein #Mutant #PI3K/AKT/mTOR pathway #Parkinson's Disease Mechanisms and Treatments #Parkinson's disease #Receptor #Signal transduction #Trehalose
- Lithium induces autophagy by inhibiting inositol monophosphatase
2005/09/26 by Sovan Sarkar, R. Andres Floto, R. Andrés Floto +7 · 34 citations
Medicine · #ATG16L1 #Apoptosis #Autophagy #Autophagy in Disease and Therapy #BAG3 #Biochemistry #Biology #Cell biology #Cytosol #Enzyme #Inositol #Lysosomal Storage Disorders Research #Mechanistic target of rapamycin #PI3K/AKT/mTOR pathway #Parkinson's Disease Mechanisms and Treatments #Receptor #Signal transduction