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Erectile dysfunction in chronic kidney disease: From pathophysiology to management

2015/01/01 by Eirini Papadopoulou · 1 citation
Medicine · #Diabetes mellitus #Disease #Endocrinology #Endothelial dysfunction #Environmental health #Erectile dysfunction #Hormonal and reproductive studies #Incidence (geometry) #Intensive care medicine #Internal medicine #Kidney disease #Life expectancy #Medicine #Pathophysiology #Population #Quality of life (healthcare) #Sexual dysfunction #Sexual function #Sexual function and dysfunction studies #Urinary Bladder and Prostate Research

paper · pdf · doi:10.5527/wjn.v4.i3.379

openalex publication_date 2015/01/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/31

Abstract

Chronic kidney disease (CKD) is encountered in millions of people worldwide, with continuously rising incidence during the past decades, affecting their quality of life despite the increase of life expectancy in these patients. Disturbance of sexual function is common among men with CKD, as both conditions share common pathophysiological causes, such as vascular or hormonal abnormalities and are both affected by similar coexisting comorbid conditions such as cardiovascular disease, hypertension and diabetes mellitus. The estimated prevalence of erectile dysfunction reaches 70% in end stage renal disease patients. Nevertheless, sexual dysfunction remains under-recognized and under-treated in a high proportion of these patients, a fact which should raise awareness among clinicians. A multifactorial approach in management and treatment is undoubtedly required in order to improve patients' quality of life and cardiovascular outcomes.

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