- Nucleotide-dependent switching and RIPb effector recognition of the barley susceptibility factor RACB
2026/05/21 by Mariam Mohamadi, Mariem Bradai, Robert Janowski +7 · 2 voices
Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · #CDC42 #Cellular transport and secretion #Cytoskeleton #Effector #Fungal and yeast genetics research #GTPase #GTPase-activating protein #Microtubule #Plant-Microbe Interactions and Immunity #Protein–protein interaction #Signal transduction #Structural biology
- Structure of the lysosomal KICSTOR-GATOR1-SAMTOR nutrient-sensing supercomplex
2026/01/08 by Christopher J. Lupton, Charles Bayly-Jones, Shuqi Dong +12 · 2 voices · 1 citation
Biochemistry, Genetics and Molecular Biology · #Adenosine triphosphate #Amino acid #Cellular transport and secretion #Docking (animal) #GTP' #GTPase #Guanosine #Guanosine triphosphate #Lysosome #Microtubule and mitosis dynamics #PI3K/AKT/mTOR signaling in cancer #Triphosphatase #mTORC1
- HuR–miRNA complex activates RAS GTPase RalA to facilitate endosome targeting and extracellular export of miRNAs
2024/02/14 by Syamantak Ghosh, Sourav Hom Choudhury, Kamalika Mukherjee +1 · 7 citations
Biochemistry, Genetics and Molecular Biology · #Biochemistry #Biology #Cell #Cell biology #ESCRT #Endocytic cycle #Endocytosis #Endosome #Enzyme #Extracellular #Extracellular vesicle #Extracellular vesicles in disease #GTPase #Gene #Intracellular #Lysosome #MicroRNA in disease regulation #Microvesicles #RNA Interference and Gene Delivery #Rab #Signal transduction #Small GTPase #microRNA
- The small GTPase Sar1, control centre of COPII trafficking
2023/02/04 by Sander E. Van der Verren, Giulia Zanetti · 24 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Biology #COPII #Cell biology #Cellular transport and secretion #Endoplasmic Reticulum Stress and Disease #Endoplasmic reticulum #GTPase #Golgi apparatus #Pancreatic function and diabetes #Secretory pathway
- The GTPase KRAS suppresses the p53 tumor suppressor by activating the NRF2-regulated antioxidant defense system in cancer cells
2020/01/30 by Hua Yang, Shengyan Xiang, Aslamuzzaman Kazi +2 · 17 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · #Antioxidant #Biochemistry #Biology #Cancer #Cancer cell #Cancer research #Cell biology #Chemistry #Colorectal cancer #Free Radicals and Antioxidants #GTPase #Genetics #Genomics, phytochemicals, and oxidative stress #Glutathione Transferases and Polymorphisms #KRAS #Signal transduction #Small GTPase #Suppressor
- Ragulator and SLC38A9 activate the Rag GTPases through noncanonical GEF mechanisms
2018/09/04 by Kuang Shen, David M. Sabatini · 26 citations
Biochemistry, Genetics and Molecular Biology · #Biology #Cell biology #Cellular transport and secretion #GTPase #PI3K/AKT/mTOR signaling in cancer #Protein Kinase Regulation and GTPase Signaling
- Actin cytoskeleton dynamics in mammalian oocyte meiosis†
2018/07/13 by Xing Duan, Shao‐Chen Sun, Shao-Chen Sun · 26 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Actin cytoskeleton #Biology #Cell #Cell biology #Cell division #Chromosome #Chromosome segregation #Cytoskeleton #Embryo #Formins #GTPase #Genetics #Germinal vesicle #Meiosis #Microtubule and mitosis dynamics #Mitosis #Nuclear Structure and Function #Oocyte #Polar body #Reproductive Biology and Fertility #Spindle apparatus
- Rho signaling research: history, current status and future directions
2018/05/11 by Shuh Narumiya, Dean Thumkeo · 25 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Biology #CDC42 #Cell biology #Effector #Flavonoids in Medical Research #GTPase #Gene #Genetics #Medicinal plant effects and applications #Protein Kinase Regulation and GTPase Signaling #RHOA #RHOB #RhoC #Signal transduction #Subfamily
- Eight human OPA1 isoforms, long and short: What are they for?
2018/01/31 by Valentina Del Dotto, Mario Fogazza, Valerio Carelli +3 · 29 citations
Biochemistry, Genetics and Molecular Biology · #ATP Synthase and ATPases Research #Biology #Cell biology #Computational biology #Dynamin #GTPase #Gene #Gene isoform #Genetics #Metabolism and Genetic Disorders #Mitochondrial DNA #Mitochondrial Function and Pathology #Mitochondrion #mitochondrial fusion
- The RanGTP Pathway: From Nucleo-Cytoplasmic Transport to Spindle Assembly and Beyond
2016/01/11 by Tommaso Cavazza, Isabelle Vernos · 1 citation
Biochemistry, Genetics and Molecular Biology · #Biochemistry #Biology #Cell #Cell biology #Cell division #Cell nucleus #Cytoplasm #GTPase #Microtubule and mitosis dynamics #Mitosis #Nuclear Structure and Function #Nuclear transport #Ran #Signal transduction #Small GTPase #Spindle apparatus #Ubiquitin and proteasome pathways
- Identification of two evolutionarily conserved genes regulating processing of engulfed apoptotic cells
2010/03/21 by Jason M. Kinchen, Kodi S. Ravichandran · 1 citation
Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · Medicine · #Apoptosis #Autophagy #Autophagy in Disease and Therapy #Biology #Caenorhabditis elegans #Cell #Cell biology #Cellular transport and secretion #Effector #GTPase #Gene #Genetics #Internalization #Multicellular organism #Phagocytosis #Phagocytosis and Immune Regulation #Phagosome #Rab #Signal transduction #Small GTPase
- Human Misato regulates mitochondrial distribution and morphology
2007/02/16 by Masashi Kimura, Yukio Okano · 16 citations
Biochemistry, Genetics and Molecular Biology · #Biochemistry #Biology #Cell #Cell biology #Cell culture #Complementary DNA #Drosophila melanogaster #Fungal and yeast genetics research #GTPase #Gene #Genetics #HeLa #Mitochondrial DNA #Mitochondrial Function and Pathology #Mitochondrion #Molecular biology #Photosynthetic Processes and Mechanisms #Transfection
- Disruption of Toxoplasma gondii Parasitophorous Vacuoles by the Mouse p47-Resistance GTPases
2005/11/16 by Sascha Martens, Iana Parvanova, Jens Zerrahn +4 · 5 citations
Immunology and Microbiology · Medicine · Chemistry · #Toxoplasma gondii Research Studies #Cytomegalovirus and herpesvirus research #Herpesvirus Infections and Treatments #Toxoplasma gondii #GTPase #Vacuole #Cell biology #Chemistry #Biology #Immunology #Cytoplasm
- High-Resolution Dissection of Phagosome Maturation Reveals Distinct Membrane Trafficking Phases
2002/10/01 by Daniel Gotthardt, Hans-Jörg Warnatz, Oliver Henschel +3 · 2 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Cellular transport and secretion #Lipid Membrane Structure and Behavior #Erythrocyte Function and Pathophysiology #Phagosome #Biology #Cell biology #Endocytosis #Endosome #Rab #Exocytosis #Endocytic cycle #Golgi apparatus #Cytoskeleton #Lysosome #Dictyostelium discoideum #Cathepsin D #Phagocytosis #Biochemistry #GTPase #Endoplasmic reticulum #Intracellular #Membrane #Cell