Eight human OPA1 isoforms, long and short: What are they for?

2018/01/31 by Valentina Del Dotto, Mario Fogazza, Valerio Carelli +3 · 28 citations
Biochemistry, Genetics and Molecular Biology · #Mitochondrial Function and Pathology #ATP Synthase and ATPases Research #Metabolism and Genetic Disorders

paper · doi:10.1016/j.bbabio.2018.01.005

Cited by

• Lysine acetylation modulates s‐OPA1 GTPase activity and oligomerization in mitochondrial membrane remodeling
• YME1L1 Dysfunction Associated With 3‐Methylglutaconic Aciduria
• Shaping the mitochondrial inner membrane in health and disease
• Mitochondrial Morphofunction in Mammalian Cells. [europepmc]
• Posttranslational modifications of mitochondrial fission and fusion proteins in cardiac physiology and pathophysiology. [europepmc]
• Two forms of Opa1 cooperate to complete fusion of the mitochondrial inner-membrane. [europepmc]
• Structural analysis of a trimeric assembly of the mitochondrial dynamin-like GTPase Mgm1. [europepmc]
• Interplay of mitochondrial fission-fusion with cell cycle regulation: Possible impacts on stem cell and organismal aging. [europepmc]
• Mitochondrial damage & lipid signaling in traumatic brain injury. [europepmc]
• Structural insights into G domain dimerization and pathogenic mutation of OPA1. [europepmc]
• The essential functions of mitochondrial dynamics in immune cells. [europepmc]
• Targeting Multiple Mitochondrial Processes by a Metabolic Modulator Prevents Sarcopenia and Cognitive Decline in SAMP8 Mice. [europepmc]
• Mitochondria Targeted Viral Replication and Survival Strategies-Prospective on SARS-CoV-2. [europepmc]
• Inhibition of the mitochondrial ATPase function by IF1 changes the spatiotemporal organization of ATP synthase. [europepmc]
• Therapeutic Options in Hereditary Optic Neuropathies. [europepmc]
• The Impact of Mitochondrial Fission-Stimulated ROS Production on Pro-Apoptotic Chemotherapy. [europepmc]
• Emerging Roles of the MICOS Complex in Cristae Dynamics and Biogenesis. [europepmc]
• Redox-Mediated Regulation of Mitochondrial Biogenesis, Dynamics, and Respiratory Chain Assembly in Yeast and Human Cells. [europepmc]
• Molecular Machinery and Pathophysiology of Mitochondrial Dynamics. [europepmc]
• Pathways shaping the mitochondrial inner membrane. [europepmc]
• Mitochondrial Membrane Remodeling. [europepmc]
• Mitochondrial protein dysfunction in pathogenesis of neurological diseases. [europepmc]
• Mitochondrial dynamics involves molecular and mechanical events in motility, fusion and fission. [europepmc]
• OPA1 helical structures give perspective to mitochondrial dysfunction. [europepmc]
• Mitochondrial proteome research: the road ahead. [europepmc]
• Mitochondrial network dynamics in pulmonary disease: Bridging the gap between inflammation, oxidative stress, and bioenergetics. [europepmc]
• Fast and deep phosphoproteome analysis with the Orbitrap Astral mass spectrometer. [europepmc]
• Mitochondrial membrane potential and oxidative stress interact to regulate Oma1-dependent processing of Opa1 and mitochondrial dynamics. [europepmc]