1. Gene ancestries reveal diverse microbial associations during eukaryogenesis
   2026/06/10 by Moisès Bernabeu, Saioa Manzano-Morales, Marina Marcet-Houben +1 · 2 voices
   Biochemistry, Genetics and Molecular Biology · Environmental Science · #Ancestor #Bacteriophages and microbial interactions #Gene #Genome #Genomics and Phylogenetic Studies #Horizontal gene transfer #Phylogenetic tree #Phylogenetics #Proteome #Protist diversity and phylogeny #Three-domain system #Tree of life (biology)
2. SARS-CoV-2 peptide fragments selectively dysregulate specific immune cell populations via Gaussian curvature targeting
   2026/01/08 by Yue Zhang, Carlos Silvestre-Roig, Han Fu +32 · 2 voices
   Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · #Antimicrobial Peptides and Activities #Cell #Cell type #Chaperone (clinical) #Immune system #Immunotherapy and Immune Responses #In vitro #Peripheral blood mononuclear cell #Proteases #Proteolysis #Proteome #Receptor #vaccines and immunoinformatics approaches
3. AlphaFlex: Ensembles of the human proteome representing disordered regions
   2025/11/25 by Zi Hao Liu, Oufan Zhang, Stefano De Castro +9 · 1 voice · 1 citation
   Biochemistry, Genetics and Molecular Biology · #Bioinformatics and Genomic Networks #Conformational ensembles #Context (archaeology) #Folding (DSP implementation) #Human proteins #Human proteome project #Intrinsically disordered proteins #Machine Learning in Bioinformatics #Protein Structure and Dynamics #Protein folding #Protein structure #Proteome
4. AF-CALVADOS: AlphaFold-guided simulations of multi-domain proteins at the proteome level
   2025/10/19 by Sören von Bülow, Kristoffer E. Johansson, Kresten Lindorff‐Larsen · 1 voice · 5 citations
   Chemistry · #Advanced Proteomics Techniques and Applications #Function (biology) #Human proteome project #Intrinsically disordered proteins #Molecular dynamics #Protein structure #Protein–protein interaction #Proteome #Scalability
5. tRNA-modifying enzymes in bacterial stress adaptation
   2025/10/01 by Louna Fruchard, Claudia Salinas, André Carvalho +1 · 1 voice · 5 citations
   Biochemistry, Genetics and Molecular Biology · Medicine · #Adaptation (eye) #Bacteria #Bacterial protein #Enzyme #Microbial metabolism #Peptidase Inhibition and Analysis #Proteome #RNA and protein synthesis mechanisms #RNA modifications and cancer #Transfer RNA #Translation (biology)
6. Mutation-induced filaments of folded proteins are inert and non-toxic in a cellular system
   2025/09/15 by Tal Levin, Hector Garcia‐Seisdedos, Arseniy Lobov +6 · 1 voice · 4 citations
   Biochemistry, Genetics and Molecular Biology · #Biochemical and Molecular Research #Cellular compartment #Colocalization #Intracellular #Protein aggregation #Protein folding #Proteome #Proteomics #Proteostasis #RNA modifications and cancer #Ubiquitin and proteasome pathways
7. Uukuniemi virus infection causes a pervasive remodelling of the RNA-binding proteome in tick cells
   2025/08/04 by Alexandra Wilson, Wael Kamel, Kelsey Davies +11 · 2 voices
   Agricultural and Biological Sciences · Medicine · #Biology #Cell biology #Gene #Genetics #Immunoprecipitation #Proteome #RNA #RNA-binding protein #Ribonucleoprotein #VP40 #Vector-Borne Animal Diseases #Viral Infections and Outbreaks Research #Viral Infections and Vectors #Viral replication #Virology #Virus
8. Multi-omics landscape and molecular basis of radiation tolerance in a tardigrade
   2024/10/24 by Lei Li, Z. W. Ge, Shihao Liu +33 · 1 voice · 16 citations
   Agricultural and Biological Sciences · Medicine · #Biochemistry #Biocrusts and Microbial Ecology #Biology #Botany #Cell biology #Computational biology #Cryptobiosis #DNA #DNA damage #DNA repair #Enzyme #Gene #Gene expression #Genetics #NAD+ kinase #Nicotinamide adenine dinucleotide #PARP1 #Poly ADP ribose polymerase #Polymerase #Proteome #Spaceflight effects on biology #Tardigrade #Tardigrade Biology and Ecology #Transcriptome
9. Comprehensive Overview of Bottom-up Proteomics using Mass Spectrometry
   2023/11/13 by Yuming Jiang, Devasahayam Arokia Balaya Rex, Jiang, Yuming +36 · 3 voices · 1 citation
   Biochemistry, Genetics and Molecular Biology · Chemistry · #Advanced Proteomics Techniques and Applications #Biochemistry #Bioinformatics #Biology #Bottom-up proteomics #Chemistry #Chromatography #Computational biology #Computer science #Identification (biology) #Mass Spectrometry Techniques and Applications #Mass spectrometry #Metabolomics and Mass Spectrometry Studies #Protein mass spectrometry #Proteome #Proteomics #Quantitative proteomics #Shotgun proteomics #Tandem mass spectrometry #Workflow #q-bio.QM
10. Arabinogalactan-proteins of Zostera marina L. contain unique glycan structures and provide insight into adaption processes to saline environments
    2020/05/19 by Lukáš Pfeifer, Thomas Shafee, Kim L. Johnson +2 · 1 citation
    Agricultural and Biological Sciences · Nursing · Chemistry · #Polysaccharides and Plant Cell Walls #Seaweed-derived Bioactive Compounds #Microbial Metabolites in Food Biotechnology #Glycan #Zostera marina #Biochemistry #Proteome #Isothermal titration calorimetry #Cell wall #Biology #Arabinogalactan #Botany #Seagrass #Chemistry #Computational biology #Cell biology #Ecology #Ecosystem #Glycoprotein
11. 2H-Azirine-Based Reagents for Chemoselective Bioconjugation at Carboxyl Residues Inside Live Cells
    2020/03/11 by Nan Ma, Jun Hu, Zhi-Min Zhang +10 · 29 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · #Amino acid #Biochemistry #Bioconjugation #Bioorthogonal chemistry #Chemical Synthesis and Analysis #Chemical biology #Chemical modification #Chemistry #Click Chemistry and Applications #Click chemistry #Combinatorial chemistry #Covalent bond #Cysteine #Enzyme #Lysine #Organic chemistry #Posttranslational modification #Proteome #Reagent #Synthesis and Catalytic Reactions
12. Cell-Free Co-Translational Approaches for Producing Mammalian Receptors: Expanding the Cell-Free Expression Toolbox Using Nanolipoproteins
    2019/07/03 by Megan L. Shelby, Wei He, Amanda T. Dang +2 · 1 citation
    Medicine · Biochemistry, Genetics and Molecular Biology · Chemistry · #Monoclonal and Polyclonal Antibodies Research #RNA and protein synthesis mechanisms #Biochemical and Structural Characterization #Membrane protein #G protein-coupled receptor #Proteome #Cell biology #Translation (biology) #Cell #Computational biology #Membrane #Vesicle-associated membrane protein 8 #Chemistry #Biology #Biochemistry #Signal transduction #Gene #Messenger RNA
13. Identification of Conserved Candidate Vaccine Antigens in the Surface Proteome of Giardia lamblia
    2019/04/09 by Barbara J. Davids, Ching M. Liu, Elaine Hanson +11 · 1 citation
    Immunology and Microbiology · Medicine · #Amoebic Infections and Treatments #Antigen #Bioinformatics #Biology #Diarrhea #Diarrheal disease #Giardia #Giardia lamblia #Immunology #Malabsorption #Malnutrition #Medicine #Microbiology #Parasitic Infections and Diagnostics #Pathology #Proteome #Protozoa #Viral gastroenteritis research and epidemiology #Virology
14. Molecular physiology of chemical defenses in a poison frog
    2019/01/01 by Stephanie N. Caty, Aurora Alvarez‐Buylla, Gary D. Byrd +7 · 4 citations
    Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · #Alkaloid #Amphibian #Antimicrobial Peptides and Activities #Biochemistry #Biology #Botany #Chemical defense #Ecology #Gene #Neurotoxin #Proteome #Proteomics #Signaling Pathways in Disease #Venomous Animal Envenomation and Studies
15. Differences between fast and slow muscles in scallops revealed through proteomics and transcriptomics
    2018/05/21 by Xiujun Sun, Zhihong Liu, Biao Wu +4 · 1 citation
    Medicine · Biochemistry, Genetics and Molecular Biology · Environmental Science · #Cardiomyopathy and Myosin Studies #Muscle Physiology and Disorders #Marine Bivalve and Aquaculture Studies #Myosin #Adductor muscles #Biology #Myofibril #Transcriptome #Scallop #Sarcomere #Titin #Proteomics #Cell biology #Myocyte #Proteome #Myosin light-chain kinase #Gene expression #Biochemistry #Gene #Anatomy #Fishery
16. Atomic structures of low-complexity protein segments reveal kinked β sheets that assemble networks
    2018/02/09 by Michael P. Hughes, M.R. Sawaya, Michael R. Sawaya +10 · 38 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · #Biochemistry #Biology #Biophysics #Branching (polymer chemistry) #Chemistry #Computational biology #Crystallography #Intrinsically disordered proteins #Materials science #Nanotechnology #Protein Structure and Dynamics #Protein structure #Proteome #RNA Research and Splicing #RNA modifications and cancer #Stacking #Stereochemistry #Steric effects #Threading (protein sequence)
17. Proteome Data Improves Protein Function Prediction in the Interactome of Helicobacter pylori
    2018/02/07 by Stefan Wuchty, Stephan A. Müller, J. Harry Caufield +4 · 1 citation
    Medicine · Immunology and Microbiology · Biochemistry, Genetics and Molecular Biology · #Helicobacter pylori-related gastroenterology studies #Galectins and Cancer Biology #Bioinformatics and Genomic Networks #Proteome #Biology #Interactome #Computational biology #Population #Context (archaeology) #Genetics #Helicobacter pylori #Proteomics #Gene #Function (biology)
18. Definition of a High-Confidence Mitochondrial Proteome at Quantitative Scale
    2017/06/01 by Marcel Morgenstern, Sebastian B. Stiller, Philipp Lübbert +15 · 2 citations
    Biochemistry, Genetics and Molecular Biology · #ATP Synthase and ATPases Research #Biochemistry #Biology #Cell biology #Microbial Metabolic Engineering and Bioproduction #Mitochondrial Function and Pathology #Mitochondrion #Proteome #Proteomics #Submitochondrial particle
19. Salt stress–induced changes in antioxidative defense system and proteome profiles of salt-tolerant and sensitiveFrankiastrains
    2017/01/13 by Amrita Srivastava, Anumeha Singh, Satya Shila Singh +1 · 1 citation
    Agricultural and Biological Sciences · Chemistry · #Legume Nitrogen Fixing Symbiosis #Plant nutrient uptake and metabolism #Aluminum toxicity and tolerance in plants and animals #Frankia #Proteome #Superoxide dismutase #Catalase #Strain (injury) #Biology #Salt (chemistry) #Peroxidase #Botany #Biochemistry #Nitrogen fixation #Microbiology #Chemistry #Food science #Oxidative stress #Enzyme #Bacteria #Root nodule #Genetics
20. A phylogenomic data-driven exploration of viral origins and evolution
    2015/09/04 by Arshan Nasir, Gustavo Caetano‐Anollés · 1 citation
    Environmental Science · Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · #Bacteriophages and microbial interactions #Plant Virus Research Studies #Genomics and Phylogenetic Studies #Biology #Viral evolution #Evolutionary biology #Genome #Proteome #Horizontal gene transfer #Tree of life (biology) #Phylogenetics #Replicon #Molecular evolution #Computational biology #Genetics #Gene
21. Analysis of the Human Prostate-Specific Proteome Defined by Transcriptomics and Antibody-Based Profiling Identifies TMEM79 and ACOXL as Two Putative, Diagnostic Markers in Prostate Cancer
    2015/08/03 by Gillian O’Hurley, Christer Busch, Linn Fagerberg +10 · 1 citation
    Biochemistry, Genetics and Molecular Biology · Medicine · #Bioinformatics #Biology #Cancer #Cancer-related gene regulation #Computational biology #Ferroptosis and cancer prognosis #Gene #Gene expression #Gene expression profiling #Genetics #Medicine #PCA3 #Pathology #Prostate #Prostate Cancer Treatment and Research #Prostate Diseases #Prostate cancer #Prostatic Diseases #Proteome #Transcriptome
22. Defining the Human Brain Proteome Using Transcriptomics and Antibody-Based Profiling with a Focus on the Cerebral Cortex
    2015/06/15 by Evelina Sjöstedt, Linn Fagerberg, Björn M. Hallström +7 · 1 citation
    Biochemistry, Genetics and Molecular Biology · Neuroscience · #RNA Research and Splicing #Single-cell and spatial transcriptomics #Bioinformatics and Genomic Networks #Transcriptome #Biology #Gene #Human brain #Computational biology #Proteome #Gene expression #Gene expression profiling #Alternative splicing #Brain atlas #Chromatin #Genetics #Neuroscience #Messenger RNA
23. Proteome-Wide Lysine Acetylation in Cortical Astrocytes and Alterations That Occur during Infection with Brain Parasite Toxoplasma gondii
    2015/03/18 by Anne Bouchut, Aarti Chawla, Victoria Jeffers +2 · 1 citation
    Immunology and Microbiology · Medicine · #Toxoplasma gondii Research Studies #HIV Research and Treatment #Sirtuins and Resveratrol in Medicine #Acetylation #Biology #Lysine #Proteome #Cell biology #Acetyltransferase #Toxoplasma gondii #Chromatin #Gene #Biochemistry #Amino acid #Genetics
24. Targeted proteomics for biomarker discovery and validation of hepatocellular carcinoma in hepatitis C infected patients
    2015/01/01 by Mustafa Gül · 1 citation
    Chemistry · Medicine · #Advanced Proteomics Techniques and Applications #Mass Spectrometry Techniques and Applications #Hepatitis C virus research #Medicine #Hepatocellular carcinoma #Biomarker discovery #Proteomics #Biomarker #Proteome #Quantitative proteomics #Computational biology #Bioinformatics #Internal medicine #Biology
25. The human testis-specific proteome defined by transcriptomics and antibody-based profiling
    2014/03/05 by Dijana Djureinovic, Linn Fagerberg, Björn M. Hallström +4 · 2 citations
    Medicine · Biochemistry, Genetics and Molecular Biology · #Sperm and Testicular Function #Molecular Biology Techniques and Applications #Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities #Biology #Transcriptome #Sertoli cell #Gene #Gene expression profiling #Proteome #Spermatogenesis #Germ cell #Immunohistochemistry #Human proteome project #Gene expression #Testicle #Proteomics #Cell biology #Genetics #Immunology #Endocrinology
26. Integration of Cardiac Proteome Biology and Medicine by a Specialized Knowledgebase
    2013/08/22 by Chenggong Zong, Haomin Li, Hua Li +21 · 1 citation
    Chemistry · Biochemistry, Genetics and Molecular Biology · Medicine · #Advanced Proteomics Techniques and Applications #Bioinformatics and Genomic Networks #Cardiac Fibrosis and Remodeling #Proteomics #Proteome #Systems biology #Computer science #Resource (disambiguation) #Computational biology #Human proteome project #Bioinformatics #Data science #Biology
27. Macaque Proteome Response to Highly Pathogenic Avian Influenza and 1918 Reassortant Influenza Virus Infections
    2010/09/16 by Joseph N. Brown, Robert E. Palermo, Carole R. Baskin +11 · 1 citation
    Medicine · Immunology and Microbiology · Chemistry · #Influenza Virus Research Studies #interferon and immune responses #Advanced Proteomics Techniques and Applications #Biology #Virology #Influenza A virus subtype H5N1 #Macaque #H5N1 genetic structure #Influenza A virus #Highly pathogenic #Virus #Proteome #Orthomyxoviridae #Microbiology #Genetics #Infectious disease (medical specialty) #Coronavirus disease 2019 (COVID-19) #Disease
28. Genome-wide Analysis of PTB-RNA Interactions Reveals a Strategy Used by the General Splicing Repressor to Modulate Exon Inclusion or Skipping
    2009/12/01 by Yuanchao Xue, Yu Zhou, Tongbin Wu +14 · 4 citations
    Biochemistry, Genetics and Molecular Biology · #Alternative splicing #Biology #Computational biology #Exon #Exon skipping #Exonic splicing enhancer #Gene #Gene expression #Genetics #Minigene #Polypyrimidine tract #Polypyrimidine tract-binding protein #Proteome #RNA #RNA Research and Splicing #RNA and protein synthesis mechanisms #RNA modifications and cancer #RNA splicing #RNA-binding protein #Splicing factor #Transcriptome
29. Quantitative Proteomics Reveals the Function of Unconventional Ubiquitin Chains in Proteasomal Degradation
    2009/04/01 by Ping Xu, Duc M. Duong, Nicholas T. Seyfried +8 · 4 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Amino acid #Autophagy in Disease and Therapy #Biochemistry #Biology #Cell biology #Deubiquitinating enzyme #Endoplasmic Reticulum Stress and Disease #Endoplasmic reticulum #Endoplasmic-reticulum-associated protein degradation #Function (biology) #Gene #Lysine #Proteasome #Protein degradation #Proteome #Proteomics #Saccharomyces cerevisiae #Ubiquitin #Ubiquitin and proteasome pathways #Ubiquitin ligase #Ubiquitin-conjugating enzyme #Ubiquitins #Unfolded protein response #Yeast
30. The role of proteomics in dementia and Alzheimer’s disease
    2009/03/03 by Maria Zellner, Michael Veitinger, Ellen Umlauf · 14 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Advanced Proteomics Techniques and Applications #Alzheimer's disease #Alzheimer's disease research and treatments #Bioinformatics #Biology #Computational biology #Dementia #Disease #Gene #Genetics #Laser capture microdissection #Medicine #Metabolomics and Mass Spectrometry Studies #Pathology #Proteome #Proteomics #Quantitative proteomics

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