1. SARS-CoV-2 peptide fragments selectively dysregulate specific immune cell populations via Gaussian curvature targeting
   2026/01/08 by Yue Zhang, Carlos Silvestre-Roig, Han Fu +32 · 2 voices
   Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · #Antimicrobial Peptides and Activities #Cell #Cell type #Chaperone (clinical) #Immune system #Immunotherapy and Immune Responses #In vitro #Peripheral blood mononuclear cell #Proteases #Proteolysis #Proteome #Receptor #vaccines and immunoinformatics approaches
2. Catch & Release—rapid cost‐effective protein purification from plants using a DIY GFP ‐Trap‐protease approach
   2025/11/01 by Scott Schwartz, Carina Engstler, Susanne Mühlbauer +4 · 1 voice · 2 citations
   Biochemistry, Genetics and Molecular Biology · Chemistry · #Advanced Proteomics Techniques and Applications #Biochemical and Structural Characterization #Cloning (programming) #Expression vector #Fusion protein #Protease #Proteases #Protein engineering #Protein purification #Protein tag #Target protein #Transgenic Plants and Applications
3. Renal Mast Cell-Specific Proteases in the Pathogenesis of Tubulointerstitial Fibrosis
   2024/09/01 by Dmitri Atiakshin, Dmitrii Atiakshin, С. Л. Морозов +17 · 7 citations
   Immunology and Microbiology · Medicine · #Biochemistry #Biology #Cell biology #Chymase #Coagulation, Bradykinin, Polyphosphates, and Angioedema #Endocrinology #Fibrosis #Immunology #Kidney #Mast cell #Mast cells and histamine #Medicine #Nephron #Pathogenesis #Pathology #Proteases #Renal Diseases and Glomerulopathies #Tryptase
4. Dipeptidyl peptidases and E3 ligases of N-degron pathways cooperate to regulate protein stability
   2024/05/01 by Adi Shimshon, Karin Dahan, Mor Israel-Gueta +6 · 10 citations
   Biochemistry, Genetics and Molecular Biology · Medicine · #Biochemistry #Biology #Cell biology #Degron #Enzyme #Peptidase Inhibition and Analysis #Protease #Protease and Inhibitor Mechanisms #Proteases #Proteolysis #Proteostasis #Ubiquitin #Ubiquitin and proteasome pathways #Ubiquitin ligase #Ubiquitin-Protein Ligases
5. Exploring the Mechanism of Covalent Inhibition: Simulating the Binding Free Energy of α-Ketoamide Inhibitors of the Main Protease of SARS-CoV-2
   2020/11/18 by Dibyendu Mondal, Arieh Warshel · 26 citations
   Biochemistry, Genetics and Molecular Biology · Chemistry · Computer Science · #Biochemistry #Chemical Synthesis and Analysis #Chemistry #Click Chemistry and Applications #Combinatorial chemistry #Computational Drug Discovery Methods #Computational chemistry #Covalent bond #Cysteine #Deubiquitinating enzyme #Enzyme #In silico #Organic chemistry #Proteases #Stereochemistry #Ubiquitin
6. Hyperactivation of JAK1 tyrosine kinase induces stepwise, progressive pruritic dermatitis
   2016/04/24 by Takuwa Yasuda, Toshiyuki Fukada, Keigo Nishida +16 · 27 citations
   Chemistry · Immunology and Microbiology · Medicine · #Biochemistry #Biology #Cancer research #Cell biology #Chemistry #Dermatology and Skin Diseases #Enzyme #Homeostasis #Hyperactivation #Immunology #Kinase #Proteases #Reproductive System and Pregnancy #Signal transduction #Tyrosine kinase #Urticaria and Related Conditions
7. Proteolytic activation defines distinct lymphangiogenic mechanisms for VEGFC and VEGFD
   2013/08/28 by Hung Bui, Hung M. Bui, David Enis +20 · 26 citations
   Medicine · #Biochemistry #Biology #Cancer research #Cell biology #Genetics #Lymphangiogenesis #Lymphatic Disorders and Treatments #Lymphatic System and Diseases #Proteases #Vascular Malformations and Hemangiomas #Vascular endothelial growth factor #Vascular endothelial growth factor A #Vascular endothelial growth factor C
8. Transcriptomics of Wild‐Type Mice and Mice Lacking ADAMTS‐5 Activity Identifies Genes Involved in Osteoarthritis Initiation and Cartilage Destruction
   2013/02/22 by John F. Bateman, Lynn Rowley, Daniele Belluoccio +6 · 26 citations
   Biochemistry, Genetics and Molecular Biology · Medicine · #ADAMTS #Aggrecan #Aggrecanase #Anatomy #Biology #Cartilage #Cell biology #Chondrocyte #Connective Tissue Growth Factor Research #Gene #Gene expression #Gene expression profiling #Genetics #Matrix metalloproteinase #Medicine #Metalloproteinase #Osteoarthritis #Osteoarthritis Treatment and Mechanisms #Pathology #Proteases #Rheumatoid Arthritis Research and Therapies #Thrombospondin #Transcriptome #Type II collagen
9. Cysteine Protease–Dependent Mucous Disruptions and Differential Mucin Gene Expression in Giardia duodenalis Infection
   2013/01/01 by Christina Amat, Christina B. Amat, Jean‐Paul Motta +7 · 26 citations
   Immunology and Microbiology · Medicine · Physics and Astronomy · #Amoebic Infections and Treatments #Biology #Cysteine protease #Enzyme #Gene #Gene expression #Immunology #Intestinal mucosa #Medicine #Microbiology #Mucin #Mucin 2 #Mucus #Parasites and Host Interactions #Parasitic Infections and Diagnostics #Proteases #Space exploration and regulation
10. EGF-Like Factors Induce Expansion of the Cumulus Cell-Oocyte Complexes by Activating Calpain-Mediated Cell Movement
    2012/06/06 by Ikko Kawashima, Zhilin Liu, Lisa K. Mullany +4 · 13 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Biochemistry #Biology #Calpain #Calpain Protease Function and Regulation #Cell biology #Chemistry #Endocrinology #Enzyme #Extracellular matrix #Focal adhesion #Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities #Internal medicine #Medicine #Proteases #Signal transduction #Sperm and Testicular Function
11. Lysosomal pathways to cell death and their therapeutic applications
    2012/03/16 by Maruša Hafner Česen, Katarina Pegan, Aleš Špes +1 · 26 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Apoptosis #Autophagy #Autophagy in Disease and Therapy #Biochemistry #Biology #Calcium signaling and nucleotide metabolism #Caspase #Cathepsin #Cell #Cell biology #Cell death mechanisms and regulation #Cytosol #Enzyme #Extracellular #Intracellular #Lysosome #Organelle #Programmed cell death #Proteases
12. A clinical perspective of IL‐1β as the gatekeeper of inflammation
    2011/04/26 by Charles A. Dinarello · 35 citations
    Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · Medicine · #Autoimmune and Inflammatory Disorders Research #Biochemistry #Biology #Cytokine #Endogeny #Enzyme #IL-33, ST2, and ILC Pathways #Immunology #Inflammasome #Inflammasome and immune disorders #Inflammation #Proteases #Proteolysis
13. New developments in mast cell biology
    2008/10/21 by Janet Kalesnikoff, Stephen J Galli, Stephen J. Galli · 1 citation
    Immunology and Microbiology · Medicine · #Acquired immune system #Asthma and respiratory diseases #Biology #Cell biology #Cytokine #Effector #Immune system #Immunology #Innate immune system #Interleukin #Interleukin 33 #Mast cell #Mast cells and histamine #Proteases #Urticaria and Related Conditions
14. Giardia duodenalis Cathepsin B Proteases Degrade Intestinal Epithelial Interleukin-8 and Attenuate Interleukin-8-Induced Neutrophil Chemotaxis
    2008/01/01 by James A. Cotton, Amol Bhargava, Jose G. Ferraz +5 · 29 citations
    Immunology and Microbiology · Medicine · Social Sciences · #Amoebic Infections and Treatments #Biochemistry #Biology #Cathepsin #Cathepsin B #Cathepsin L1 #Chemotaxis #Cuban History and Society #Cytokine #Enzyme #Epithelium #Giardia #Immune system #Immunology #Inflammation #Interleukin #Interleukin 2 #Interleukin 8 #Intestinal epithelium #Intestinal mucosa #Latin American Literature Studies #Latin American and Latino Studies #Microbiology #Parasites and Host Interactions #Parasitic Infections and Diagnostics #Proteases
15. Protease signalling in cell death: caspases versus cysteine cathepsins
    2007/05/25 by Boris Turk, Veronika Stoka · 27 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · Nursing · #Apoptosis #Biochemistry #Biology #Calpain #Caspase #Caspase 2 #Cathepsin #Cell biology #Cell death mechanisms and regulation #Chemistry #Cysteine #Cysteine protease #Deubiquitinating enzyme #Enzyme #NF-κB Signaling Pathways #Programmed cell death #Protease #Proteases #Trace Elements in Health #Ubiquitin
16. Evaluasi Simpang Bersinyal Antara Jalan Banda - Jalan Aceh Bandung
    2006/01/01 by Renliang Yang, Yee Hwa Wong, Giang K T Nguyen +6 · 28 citations
    Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · Chemistry · Computer Science · Engineering · Medicine · #Biochemical and Structural Characterization #Biochemistry #Chemistry #Computer Science and Engineering #Cysteine #DNA ligase #Enzyme #Geotechnical and construction materials studies #Mutagenesis #Mutant #Mutation #Native chemical ligation #Peptidase Inhibition and Analysis #Peptide #Peptide bond #Physics #Phytoplasmas and Hemiptera pathogens #Proteases #Protein engineering #Protein structure #Recombinant DNA #Site-directed mutagenesis #Urban Transport Systems Analysis
17. Antimicrobial reactive oxygen and nitrogen species: concepts and controversies
    2004/10/01 by Ferric C. Fang · 1 citation
    Immunology and Microbiology · #Antimicrobial #Bacterial Infections and Vaccines #Biochemistry #Biology #Cell biology #Enzyme #Immune Response and Inflammation #Microbiology #Neutrophil, Myeloperoxidase and Oxidative Mechanisms #Phagocyte #Phagocytosis #Proteases #Reactive nitrogen species #Reactive oxygen species
18. A Multi-enzyme Cascade of Hemoglobin Proteolysis in the Intestine of Blood-feeding Hookworms
    2004/06/16 by Angela Williamson, Paolo Lecchi, Benjamin E. Turk +7 · 4 citations
    Immunology and Microbiology · Medicine · Chemistry · #Parasites and Host Interactions #Trypanosoma species research and implications #Parasitic Infections and Diagnostics #Proteases #Proteolysis #Ancylostoma caninum #Biochemistry #Biology #Enzyme #Hemoglobin #Protease #Ancylostomiasis #Microbiology #Chemistry #Molecular biology #Immunology #Helminths
19. Vaccination of Dogs with a Recombinant Cysteine Protease from the Intestine of Canine Hookworms Diminishes the Fecundity and Growth of Worms
    2004/05/07 by Alex Loukas, Jeffrey M. Bethony, Angela Williamson +7 · 1 citation
    Immunology and Microbiology · Environmental Science · Medicine · #Parasites and Host Interactions #Parasite Biology and Host Interactions #Parasitic infections in humans and animals #Ancylostoma caninum #Biology #Antibody #Vaccination #Virology #Proteases #Microbiology #Cysteine protease #Protease #Feces #Blood meal #Antigen #Titer #Immunology #Helminths #Enzyme #Biochemistry
20. Comparison, Characterization, and Identification of Proteases and Protease Inhibitors in Epididymal Fluids of Domestic Mammals. Matrix Metalloproteinases Are Major Fluid Gelatinases1
    2002/05/01 by Sonia Métayer, Sonia Métayer, Françoise Dacheux +5 · 7 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Anatomy #BOAR #Biochemistry #Biology #Enzyme #Gelatinase #Gelatinases #Matrix metalloproteinase #Metalloproteinase #Molecular biology #PMSF #Periodontal Regeneration and Treatments #Protease #Protease and Inhibitor Mechanisms #Proteases #Protein Hydrolysis and Bioactive Peptides #Semen #Serine #Serine protease #Zymography
21. Nitrogen metabolism and remobilization during senescence
    2002/04/15 by Stefan Hörtensteiner, Urs Feller · 33 citations
    Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · Chemistry · #Biochemistry #Biology #Botany #Catabolism #Cell biology #Chemistry #Chlorophyll #Chloroplast #Cytoplasm #Enzyme #Metabolism #Photosynthetic Processes and Mechanisms #Plant Stress Responses and Tolerance #Plant nutrient uptake and metabolism #Proteases #Protein degradation #Proteolysis #RuBisCO #Senescence #Thylakoid #Vacuole
22. Calpain and caspase: can you tell the difference?
    2000/01/01 by Kevin K.W Wang, Kevin Wang · 1 citation
    Biochemistry, Genetics and Molecular Biology · Medicine · Neuroscience · #Apoptosis #Biochemistry #Biology #Calpain #Calpain Protease Function and Regulation #Calpastatin #Caspase #Caspase 3 #Cell biology #Cell death mechanisms and regulation #Cysteine protease #DNA fragmentation #Enzyme #Internal medicine #Kinase #Medicine #Neurodegeneration #Neuroscience #Programmed cell death #Protease #Proteases #Proteolysis #Venomous Animal Envenomation and Studies
23. Neutrophils and renal failure
    1999/08/01 by Michael Heinzelmann, Mark Mercer‐Jones, Mark A. Mercer-Jones +1 · 1 citation
    Immunology and Microbiology · Medicine · #Acute Kidney Injury Research #Acute kidney injury #Biochemistry #Biology #Cathepsin G #Cell biology #Chemotaxis #Enzyme #Immune Response and Inflammation #Immunology #Inflammation #Internal medicine #Kidney #Medicine #Myeloperoxidase #NADPH oxidase #Neutrophil elastase #Neutrophil extracellular traps #Neutrophil, Myeloperoxidase and Oxidative Mechanisms #Nicotinamide adenine dinucleotide phosphate #Oxidase test #Proteases #Reactive oxygen species #Receptor
24. Calpain inhibitors, but not caspase inhibitors, prevent actin proteolysis and DNA fragmentation during apoptosis
    1998/03/15 by Pascal Villa, William J. Henzel, M. Sensenbrenner +2 · 1 citation
    Biochemistry, Genetics and Molecular Biology · #Calpain Protease Function and Regulation #Cell death mechanisms and regulation #Venomous Animal Envenomation and Studies #Biology #Calpain #Proteases #DNA fragmentation #Cell biology #Programmed cell death #Apoptosis #Caspase #NLRP1 #Fragmentation (computing) #Proteolysis #Apoptotic DNA fragmentation #Actin #Biochemistry #Enzyme
25. A Comprehensive Genetic Study of Streptococcal Immunoglobulin A1 Proteases: Evidence for Recombination within and between Species
    1998/01/01 by Knud Poulsen, Jesper Reinholdt, Christina Jespersgaard +4 · 17 citations
    Medicine · #Bacteria #Biochemistry #Biology #Biovar #Enzyme #Gene #Genetics #Microbiology #Peptide sequence #Pneumonia and Respiratory Infections #Protease #Proteases #Streptococcal Infections and Treatments #Streptococcus #Streptococcus gordonii #Streptococcus mitis #Streptococcus oralis
26. Actin cleavage by CPP-32/apopain during the development of apoptosis
    1997/03/06 by Tetsuo Mashima, Mikihiko Naito, Kohji Noguchi +5 · 1 citation
    Biochemistry, Genetics and Molecular Biology · #Actin #Apoptosis #Biochemistry #Biology #Caspase #Cell biology #Cell death mechanisms and regulation #Cleavage (geology) #Enzyme #Molecular biology #Programmed cell death #Protease #Proteases #RNA Interference and Gene Delivery #Virus-based gene therapy research
27. Slow recovery of force in single skeletal muscle fibres
    1996/03/01 by Jan Lännergren, J. LÄNNERGREN, H. WESTERBLAD +3 · 3 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · Engineering · Medicine · Neuroscience · #Biochemistry #Biology #Biophysics #Cell biology #Chemistry #Coupling (piping) #Depolarization #Endocrinology #Enzyme #Excitation–contraction coupling #Internal medicine #Ion channel regulation and function #Materials science #Medicine #Muscle activation and electromyography studies #Muscle contraction #Neurobiology and Insect Physiology Research #Proteases #Skeletal muscle #Stimulation
28. Molecular aspects of immunoglobulin A1 degradation by oral streptococci
    1990/05/01 by J Reinholdt, Milan Tomana, M Tomana +4 · 13 citations
    Dentistry · Medicine · #Antibody #Bacteria #Biochemistry #Biology #Enzyme #Genetics #Immunoglobulin A #Immunoglobulin G #Immunology #Microbiology #Neonatal and Maternal Infections #Neuraminidase #Oral microbiology and periodontitis research #Protease #Proteases #Streptococcal Infections and Treatments #Streptococcus #Streptococcus mitis #Streptococcus oralis
29. Enzymatic activity of a synthetic 99 residue protein corresponding to the putative HIV-1 protease
    1988/07/01 by Jens Schneider, Stephen B. H. Kent, Stephen B.H. Kent · 1 citation
    Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · Medicine · #Biochemical and Molecular Research #Biochemistry #Biology #Cleavage (geology) #Enzyme #Gene #HIV Research and Treatment #HIV-1 protease #HIV/AIDS drug development and treatment #NS2-3 protease #Peptide #Peptide sequence #Protease #Protease inhibitor (pharmacology) #Proteases #Residue (chemistry) #Virology #Virus
30. The labial gland system of larvae of the imported fire ant, Solenopsis invicta Buren
    1980/02/01 by Ronald S. Petralia, R.S. Petralia, A.A. Sorensen +3 · 1 citation
    Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · Chemistry · #Amylase #Anatomy #Biochemistry #Biology #Botany #Cell biology #Chemistry #Digestion (alchemy) #Enzyme #Insect #Insect and Arachnid Ecology and Behavior #Insect and Pesticide Research #Instar #Larva #Lumen (anatomy) #Midgut #Plant and animal studies #Proteases #Secretion #Ultrastructure #Zoology

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