- Compartmentalized cytoplasmic tradewinds direct soluble proteins
2026/03/30 by Catherine G. Galbraith, Brian P. English, Ulrike Boehm +1 · 1 voice · 2 citations
Biochemistry, Genetics and Molecular Biology · #Actin #Cellular Mechanics and Interactions #Cellular transport and secretion #Compartment (ship) #Compartmentalization (fire protection) #Cytoplasm #Intracellular #RNA Research and Splicing #Transport protein #Treadmilling
- Dynamic protrusions mediate unique crawling motility in Asgard Archaea (Promethearchaeota)
2025/12/01 by Philipp Radler, Tobias Viehboeck, Zhen Hao Luo +10 · 2 voices · 1 citation
Biochemistry, Genetics and Molecular Biology · Physics and Astronomy · #Actin #Actin cytoskeleton #Archaea #Bacterial Genetics and Biotechnology #Cell #Cytoskeleton #Invadopodia #Motility #Origins and Evolution of Life #Protist diversity and phylogeny #Pseudopodia
- Paths to stability – actin regulation of adherens junction mechanics
2025/11/15 by John James, Linda Winn, Peter Mottram-Epson +1 · 1 voice · 1 citation
Biochemistry, Genetics and Molecular Biology · Medicine · #Actin #Actin cytoskeleton #Actin remodeling #Actin-binding protein #Adherens junction #Cell Adhesion Molecules Research #Cellular Mechanics and Interactions #Cellular transport and secretion #Cytoskeleton #Formins #Transcellular
- Structure of the Huntingtin F-actin complex reveals its role in cytoskeleton organization
2025/09/19 by Rémi Carpentier, J. H. Kim, Mariacristina Capizzi +15 · 1 voice · 3 citations
Biochemistry, Genetics and Molecular Biology · Neuroscience · #Actin #Actin cytoskeleton #Bridge (graph theory) #Cytoskeleton #Domain (mathematical analysis) #Function (biology) #Genetic Neurodegenerative Diseases #Huntingtin #Mitochondrial Function and Pathology #Nuclear Structure and Function #Protein domain #Vesicle
- Cracked actin filaments as mechanosensitive receptors
2024/06/17 by Vilmos Zsolnay, Margaret L. Gardel, David R. Kovar +1 · 10 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · Physics and Astronomy · #Actin #Actin cytoskeleton #Actin remodeling #Actin remodeling of neurons #Actin-binding protein #Biochemistry #Biology #Biophysics #Cardiomyopathy and Myosin Studies #Cell biology #Cellular Mechanics and Interactions #Chemistry #Cofilin #Cytoskeleton #Force Microscopy Techniques and Applications #Ion channel #MDia1 #Materials science #Mechanosensitive channels #Microfilament #Protein filament #Receptor #Treadmilling
- FHL2 anchors mitochondria to actin and adapts mitochondrial dynamics to glucose supply
2021/08/03 by Himanish Basu, Gülçin Pekkurnaz, Gulcin Pekkurnaz +7 · 25 citations
Biochemistry, Genetics and Molecular Biology · #ATP Synthase and ATPases Research #Actin #Actin cytoskeleton #Anchoring #Biochemistry #Biology #Cell #Cell biology #Cytoskeleton #Mechanism (biology) #Metabolism and Genetic Disorders #Mitochondrial Function and Pathology #Mitochondrion #Physics
- Tumor cell nuclei soften during transendothelial migration
2021/04/05 by Anya B. Roberts, Anya Burkart. Roberts, Jitao Zhang +7 · 28 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Actin #Biology #Biophysics #Cell #Cell biology #Cell migration #Cellular Mechanics and Interactions #Chemistry #Confocal #Confocal microscopy #Cytoskeleton #Extravasation #Materials science #Medicine #Nuclear Structure and Function #Optics #Pathology #Skin and Cellular Biology Research
- Fueling the cytoskeleton – links between cell metabolism and actin remodeling
2021/02/01 by Gillian DeWane, Alicia M. Salvi, Kris A. DeMali · 27 citations
Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · Medicine · #Actin #Actin cytoskeleton #Actin remodeling #Biochemistry #Biocrusts and Microbial Ecology #Biology #Cell #Cell biology #Cell migration #Cellular Mechanics and Interactions #Cytoskeleton #Spaceflight effects on biology
- Emerging Properties and Functions of Actin and Actin Filaments Inside the Nucleus
2020/12/07 by Svenja Ulferts, Bina Prajapati, Robert Grosse +1 · 1 citation
Biochemistry, Genetics and Molecular Biology · #RNA Research and Splicing #Nuclear Structure and Function #Genomics and Chromatin Dynamics #Biology #Actin #Nucleus #Actin remodeling #Cell biology #Cytoskeleton #Chromatin #Formins #Genome #Cell nucleus #Compartment (ship) #Actin cytoskeleton #Cell #Genetics #Gene
- Centering and symmetry breaking in confined contracting actomyosin\n networks
2019/07/24 by Niv Ierushalmi, Ierushalmi, Niv, Maya Malik-Garbi +11 · 2 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Engineering · Physics and Astronomy · #Actin #Biological Physics (physics.bio-ph) #Biology #Biophysics #Cell #Cell biology #Cell division #Cellular Mechanics and Interactions #Chemistry #Contraction (grammar) #Cytoplasm #FOS: Physical sciences #Fluid Dynamics and Heat Transfer #Micro and Nano Robotics #Motility #Physics #Symmetry breaking #Xenopus
- Migration through physical constraints is enabled by MAPK-induced cell softening via actin cytoskeleton re-organization
2019/05/31 by Dominika A. Rudzka, Giulia Spennati, David J. McGarry +13 · 25 citations
Biochemistry, Genetics and Molecular Biology · Engineering · Medicine · #3D Printing in Biomedical Research #Actin #Actin cytoskeleton #Biology #Cancer #Cancer Cells and Metastasis #Cancer cell #Cancer research #Cell #Cell adhesion #Cell biology #Cell migration #Cellular Mechanics and Interactions #Cytoskeleton #Focal adhesion #Genetics #Signal transduction #Vinculin
- The discovery of actin: “to see what everyone else has seen, and to think what nobody has thought”*
2019/05/15 by Beáta Bugyi, Miklós Kellermayer · 1 citation
Biochemistry, Genetics and Molecular Biology · Medicine · Chemistry · #Cellular Mechanics and Interactions #Cardiomyopathy and Myosin Studies #Microtubule and mitosis dynamics #nobody #Actin #Diversity (politics) #Chemistry #Sociology #Computer science #Biochemistry #Anthropology
- T cell receptor–triggered nuclear actin network formation drives CD4 + T cell effector functions
2019/01/04 by Nikolaos Tsopoulidis, Sheetal Kaw, Vibor Laketa +5 · 2 citations
Immunology and Microbiology · Medicine · Neuroscience · Chemistry · #T-cell and B-cell Immunology #CAR-T cell therapy research #Neuroinflammation and Neurodegeneration Mechanisms #Cell biology #Actin #Effector #Cell #T cell #Biology #Chemistry #Immunology #Biochemistry #Immune system
- Intercalated discs: cellular adhesion and signaling in heart health and diseases
2018/10/04 by Guangze Zhao, Ye Qiu, Huifang M. Zhang +1 · 1 citation
Medicine · Neuroscience · #Actin #Actin cytoskeleton #Adherens junction #Biology #Cadherin #Cardiac electrophysiology and arrhythmias #Cardiomyopathy #Cardiovascular Effects of Exercise #Catenin #Cell #Cell biology #Cytoskeleton #Desmoplakin #Gap junction #Genetic Neurodegenerative Diseases #Genetics #Heart failure #Intercalated disc #Internal medicine #Medicine #Plakoglobin #Signal transduction #Wnt signaling pathway
- Insights into the Cooperative Nature of ATP Hydrolysis in Actin Filaments
2018/09/01 by Harshwardhan H. Katkar, Aram Davtyan, Aleksander E.P. Durumeric +5 · 1 citation
Biochemistry, Genetics and Molecular Biology · Chemistry · Engineering · Materials Science · #ATP hydrolysis #ATPase #Actin #Adhesion, Friction, and Surface Interactions #Binding site #Biochemistry #Biology #Biophysics #Cellular Mechanics and Interactions #Chemical physics #Chemistry #Cooperative binding #Cooperativity #Crystallography #Granularity #Kinetics #Material Dynamics and Properties #Nucleotide #Physics #Protein filament
- ADF10 shapes the overall organization of apical actin filaments by promoting their turnover and ordering in pollen tubes
2017/10/24 by Yuxiang Jiang, Juan Wang, Yurong Xie +2 · 17 citations
Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · #Actin #Biology #Botany #Cell biology #Photosynthetic Processes and Mechanisms #Plant Molecular Biology Research #Plant Reproductive Biology #Pollen #Pollen tube #Pollination
- Actin and Actin-Binding Proteins
2016/03/17 by Thomas D. Pollard · 1 citation
Biochemistry, Genetics and Molecular Biology · Medicine · Chemistry · #Cellular Mechanics and Interactions #Cardiomyopathy and Myosin Studies #Microtubule and mitosis dynamics #Actin remodeling #Actin-binding protein #Actin #MDia1 #Biology #Cell biology #Actin remodeling of neurons #ATP hydrolysis #Microfilament #Myosin #Adenosine triphosphate #Polymerization #Biophysics #Biochemistry #Actin cytoskeleton #Cytoskeleton #Polymer #Chemistry #Cell #ATPase #Enzyme
- Actin-Depolymerizing Factor and Cofilin-1 Have Unique and Overlapping Functions in Regulating Intestinal Epithelial Junctions and Mucosal Inflammation
2016/02/14 by Dongdong Wang, Nayden G. Naydenov, Alex Feygin +3 · 24 citations
Biochemistry, Genetics and Molecular Biology · Medicine · Neuroscience · #Actin #Actin cytoskeleton #Barrier Structure and Function Studies #Biology #Cell #Cell Adhesion Molecules Research #Cell biology #Cellular Mechanics and Interactions #Cofilin #Cytoskeleton #Genetics #Immunology #Inflammation #Internal medicine #Intestinal mucosa #Medicine #Pathology #Tight junction
- β- and γ-Actins in the nucleus of human melanoma A375 cells
2015/08/03 by Marta Migocka-Patrzałek, Aleksandra Makowiecka, Dorota Nowak +3 · 1 citation
Biochemistry, Genetics and Molecular Biology · #Cellular Mechanics and Interactions #RNA Research and Splicing #Skin and Cellular Biology Research #Cytoplasm #Actin #Gene isoform #Biology #Cell nucleus #Cell biology #Nuclear export signal #Nuclear protein #Molecular biology #RNA #Transcription factor #Biochemistry #Gene
- Cadherin-11 coordinates cellular migration and extracellular matrix remodeling during aortic valve maturation
2015/07/16 by Caitlin J. Bowen, Jingjing Zhou, Derek C. Sung +1 · 25 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Actin #Anatomy #Biology #Cadherin #Calcification #Cell #Cell Adhesion Molecules Research #Cell biology #Cell migration #Congenital heart defects research #Extracellular matrix #Filopodia #Internal medicine #Medicine #Mesenchymal stem cell #RHOA #Signal transduction #Tissue Engineering and Regenerative Medicine
- In search of the primordial actin filament
2015/07/15 by Umesh Ghoshdastider, Shimin Jiang, David Popp +1 · 1 citation
Biochemistry, Genetics and Molecular Biology · Chemistry · #Protist diversity and phylogeny #Cellular transport and secretion #Microtubule and mitosis dynamics #Protein filament #Actin #Biology #Chemistry #Cell biology #Biochemistry
- Myosin regulatory light chain phosphorylation enhances cardiac β-myosin in vitro motility under load
2015/06/24 by Anastasia Karabina, Katarzyna Kaźmierczak, Katarzyna Kazmierczak +3 · 23 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Actin #Biochemistry #Biology #Biophysics #Cardiomyopathy and Myosin Studies #Cardiovascular Effects of Exercise #Cell biology #Chemistry #Gene #MYH7 #Muscle Physiology and Disorders #Mutant #Myosin #Myosin light-chain kinase #Phosphorylation
- PKC-mediated cerebral vasoconstriction: Role of myosin light chain phosphorylation versus actin cytoskeleton reorganization
2015/04/27 by Ahmed F. El-Yazbi, Ahmed F. El‐Yazbi, Khaled S. Abd‐Elrahman +3 · 19 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Actin #Actin cytoskeleton #Biochemistry #Biology #Cell biology #Cytoskeleton #Endocrinology #Mitochondrial Function and Pathology #Myosin #Myosin light-chain kinase #Myosin-light-chain phosphatase #Nitric Oxide and Endothelin Effects #Phosphorylation #Protein kinase C #Retinal Development and Disorders #Vasoconstriction
- The evolution of compositionally and functionally distinct actin filaments
2015/03/19 by Peter W. Gunning, Umesh Ghoshdastider, Shane Whitaker +3 · 30 citations
Biochemistry, Genetics and Molecular Biology · #Actin #Actin cytoskeleton #Actin remodeling #Actin-binding protein #Biology #Cell #Cell biology #Cellular Mechanics and Interactions #Cytoskeleton #Evolutionary biology #Fungal and yeast genetics research #Gene #Genetics #Homology (biology) #Microtubule and mitosis dynamics #Phylogenetic tree #Protein filament
- Active diffusion positions the nucleus in mouse oocytes
2015/03/16 by Maria Almonacid, Wylie W. Ahmed, Wylie Ahmed +7 · 1 citation
Biochemistry, Genetics and Molecular Biology · Medicine · #Actin #Biology #Cell #Cell biology #Cellular Mechanics and Interactions #Centrosome #Cytoplasm #Embryo #Genetics #Live cell imaging #Microtubule #Microtubule and mitosis dynamics #Motor protein #Myosin #Nucleus #Oocyte #Organelle #Reproductive Biology and Fertility
- Structure of the F-actin–tropomyosin complex
2014/12/01 by Julian von der Ecken, Mirco Müller, William Lehman +3 · 2 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Actin #Actin cytoskeleton #Actin remodeling #Actin-binding protein #Actinin #Biochemistry #Biology #Biophysics #Cardiomyopathy and Myosin Studies #Cardiovascular Effects of Exercise #Cell #Cell biology #Cellular Mechanics and Interactions #Chemistry #Cytoskeleton #MDia1 #Microfilament #Myofilament #Myosin #Myosin head #Myosin light-chain kinase #Protein filament #Treadmilling #Tropomyosin
- Capture of microtubule plus-ends at the actin cortex promotes axophilic neuronal migration by enhancing microtubule tension in the leading process
2014/11/27 by B. Ian Hutchins, Susan Wray · 1 citation
Biochemistry, Genetics and Molecular Biology · Neuroscience · #Microtubule and mitosis dynamics #Cellular Mechanics and Interactions #Cellular transport and secretion #Microtubule #Cell biology #Biology #Cytoskeleton #Neuroscience #Cell migration #Microtubule organizing center #Actin #Cell #Centrosome #Genetics #Cell cycle
- Unraveling the Mystery of ATP Hydrolysis in Actin Filaments
2014/09/02 by Martin McCullagh, Marissa G. Saunders, Gregory A. Voth · 2 citations
Biochemistry, Genetics and Molecular Biology · Materials Science · Chemistry · #Protein Structure and Dynamics #Cellular Mechanics and Interactions #Block Copolymer Self-Assembly #Chemistry #ATP hydrolysis #Protein filament #Actin #Hydrolysis #Metadynamics #Monomer #Biophysics #Biochemistry #Computational chemistry #Organic chemistry #Polymer #ATPase #Molecular dynamics #Enzyme
- Cytoskeletal tropomyosins: choreographers of actin filament functional diversity
2013/07/31 by Howard Vindin, Peter W. Gunning · 1 citation
Medicine · Biochemistry, Genetics and Molecular Biology · #Cardiomyopathy and Myosin Studies #Cellular Mechanics and Interactions #Muscle Physiology and Disorders #Cytoskeleton #Actin #Biology #Cell biology #Protein filament #Tropomyosin #Actin remodeling #Actin cytoskeleton #Actin-binding protein #Functional diversity #Cell #Biochemistry #Ecology
- The tension mounts: Stress fibers as force-generating mechanotransducers
2013/01/07 by Keith Burridge, Erika S. Wittchen · 28 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Actin #Anatomy #Biology #Biophysics #Cell #Cell biology #Cellular Mechanics and Interactions #Composite material #Cytoskeleton #Erythrocyte Function and Pathophysiology #Genetics #Materials science #Mechanosensitive channels #Myocyte #Myosin #Sarcomere #Skin and Cellular Biology Research #Stress fiber #Structural engineering #Tensegrity #Tension (geology) #Ultimate tensile strength
more