Cadherin-11 coordinates cellular migration and extracellular matrix remodeling during aortic valve maturation

2015/07/16 by Caitlin J. Bowen, Jingjing Zhou, Derek C. Sung +1 · 25 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Congenital heart defects research #Tissue Engineering and Regenerative Medicine #Cell Adhesion Molecules Research

paper · doi:10.1016/j.ydbio.2015.07.012

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• Cadherin-11 Overexpression Induces Extracellular Matrix Remodeling and Calcification in Mature Aortic Valves. [europepmc]
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• The Endocardium and Heart Valves. [europepmc]
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• Current Evidence and Future Perspectives on Pharmacological Treatment of Calcific Aortic Valve Stenosis. [europepmc]
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• Cadherin 11 Promotes Immunosuppression and Extracellular Matrix Deposition to Support Growth of Pancreatic Tumors and Resistance to Gemcitabine in Mice. [europepmc]
• Research progress in the role and mechanism of Cadherin-11 in different diseases. [europepmc]
• Lactic acid promotes metastatic niche formation in bone metastasis of colorectal cancer. [europepmc]
• KPT-330 Prevents Aortic Valve Calcification via a Novel C/EBPβ Signaling Pathway. [europepmc]
• Side-specific valvular endothelial-interstitial cell mechano-communication via cadherin-11. [europepmc]
• Impaired macrophage trafficking and increased helper T-cell recruitment with loss of cadherin-11 in atherosclerotic immune response. [europepmc]
• Towards Personalized Therapy of Aortic Stenosis. [europepmc]
• Identification of Rare Variants in Right Ventricular Outflow Tract Obstruction Congenital Heart Disease by Whole-Exome Sequencing. [europepmc]
• Soft-Tissue Material Properties and Mechanogenetics during Cardiovascular Development. [europepmc]
• Non-cardiomyocytes in the heart in embryo development, health, and disease, a single-cell perspective. [europepmc]
• Angiopoietin-like 2 is essential to aortic valve development in mice. [europepmc]
• Rho A/ROCK1 signaling-mediated metabolic reprogramming of valvular interstitial cells toward Warburg effect accelerates aortic valve calcification via AMPK/RUNX2 axis. [europepmc]
• Inhibition of miR-101-3p prevents human aortic valve interstitial cell calcification through regulation of CDH11/SOX9 expression. [europepmc]
• Future prospects in the tissue engineering of heart valves: a focus on the role of stem cells. [europepmc]
• Human and porcine aortic valve endothelial and interstitial cell isolation and characterization. [europepmc]