2019/05/15 by Beáta Bugyi, Miklós Kellermayer · 1 citation
Biochemistry, Genetics and Molecular Biology · Medicine · Chemistry · #Cellular Mechanics and Interactions #Cardiomyopathy and Myosin Studies #Microtubule and mitosis dynamics #nobody #Actin #Diversity (politics) #Chemistry #Sociology #Computer science #Biochemistry #Anthropology
paper · pdf · doi:10.1007/s10974-019-09515-z
openalex publication_date 2019/05/15 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/31
Actin is among the most highly abundant and ubiquitous proteins in eukaryotic cells. The structure, dynamics and functional diversity of actin have continued to mesmerise cell and molecular biologists, biophysicists and physiologists for more than three quarters of a century. The discovery and initial characterization of actin, which took place in the laboratory of Albert Szent-Györgyi by Ilona Banga and Brúnó F. Straub during the second world war in Hungary, is a remarkable and inspiring moment in the history of science. Many of the early thoughts and ideas on the properties and functions of actin and particularly actomyosin, which are referred to in this short historical overview, resonate freshly even today.