- Metabolic adaptation and fragility in healthy 3D in vitro skeletal muscle tissues exposed to chronic fatigue syndrome and Long COVID-19 sera
2025/07/31 by Sheeza Mughal, Félix Andújar-Sánchez, María Sabater-Arcis +9 · 3 voices · 1 citation
Medicine · #Biology #Cell biology #Chronic fatigue syndrome #Endocrinology #Exercise and Physiological Responses #Fibromyalgia and Chronic Fatigue Syndrome Research #Glycolysis #Internal medicine #Long-Term Effects of COVID-19 #Medicine #Metabolism #Mitochondrion #Muscle hypertrophy #Myocyte #Skeletal muscle
- Nodal modulator (NOMO) is a force-bearing transmembrane protein required for muscle differentiation
2025/05/31 by Brigitte S. Naughton, Swapnil C. Devarkar, Vanessa Todorow +8 · 2 voices · 2 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · Physics and Astronomy · #Anatomy #Biochemistry #Biology #Biophysics #C2C12 #Cardiomyopathy and Myosin Studies #Cell biology #Cellular Mechanics and Interactions #Chemistry #Force Microscopy Techniques and Applications #Myocyte #Myogenesis #Receptor #Transmembrane protein
- Mavacamten has a differential impact on force generation in myofibrils from rabbit psoas and human cardiac muscle
2021/04/23 by Beatrice Scellini, Nicoletta Piroddi, Marica Dente +6 · 28 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Actin #Anatomy #Biochemistry #Biology #Biophysics #Cardiac muscle #Cardiomyopathy and Myosin Studies #Cardiovascular Effects of Exercise #Cell biology #Chemistry #Contraction (grammar) #Endocrinology #Internal medicine #Isometric exercise #Medicine #Muscle Physiology and Disorders #Muscle contraction #Myocyte #Myofibril #Myosin #Sarcomere #Skeletal muscle
- In Situ Expansion, Differentiation, and Electromechanical Coupling of Human Cardiac Muscle in a 3D Bioprinted, Chambered Organoid
2020/03/31 by Molly E. Kupfer, Molly Kupfer, Wei-Han Lin +15 · 27 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Engineering · Medicine · #3D Printing in Biomedical Research #Anatomy #Biochemistry #Biology #Biomedical engineering #Cardiac muscle #Cell biology #Cellular differentiation #Chemistry #Embryonic stem cell #Extracellular matrix #Induced pluripotent stem cell #Medicine #Myocyte #Organoid #Pluripotent Stem Cells Research #Regenerative medicine #Stem cell #Tissue Engineering and Regenerative Medicine #Tissue engineering
- FoxO Transcription Factors Are Critical Regulators of Diabetes-Related Muscle Atrophy
2018/12/06 by Brian T. O’Neill, Gourav Bhardwaj, Christie M. Penniman +11 · 26 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Adipose Tissue and Metabolism #Apoptosis #Autophagy #Biochemistry #Biology #Cell biology #Diabetes mellitus #Endocrinology #FOXO1 #Insulin #Internal medicine #Medicine #Muscle Physiology and Disorders #Muscle atrophy #Myocyte #Phosphorylation #Protein degradation #Protein kinase B #Sirtuins and Resveratrol in Medicine #Skeletal muscle #Streptozotocin
- MicroRNA‐382 silencing induces a mitonuclear protein imbalance and activates the mitochondrial unfolded protein response in muscle cells
2018/11/11 by Dennis Dahlmans, Alexandre Houzelle, Pénélope Andreux +8 · 13 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Adipose Tissue and Metabolism #Biology #C2C12 #Cell biology #DNAJA3 #Gene #Gene silencing #Genetics #HSPA9 #MicroRNA in disease regulation #Mitochondrial DNA #Mitochondrial Function and Pathology #Mitochondrial biogenesis #Mitochondrion #Molecular biology #Myocyte #Myogenesis #mitochondrial fusion
- Human Induced Pluripotent Stem Cell–Derived Cardiomyocytes as Models for Cardiac Channelopathies
2018/07/05 by Priyanka Garg, Vivek Garg, Rajani Shrestha +3 · 25 citations
Biochemistry, Genetics and Molecular Biology · Medicine · Neuroscience · #Bioinformatics #Biology #Cardiac action potential #Cardiac arrhythmia #Cardiac electrophysiology #Cardiac electrophysiology and arrhythmias #Cardiac myocyte #Disease #Electrophysiology #Embryonic stem cell #Genetics #Induced pluripotent stem cell #Internal medicine #Ion channel #Ion channel regulation and function #Medicine #Myocyte #Neuroscience #Neuroscience and Neural Engineering #Population #Receptor #Repolarization #Sudden cardiac death
- Differences between fast and slow muscles in scallops revealed through proteomics and transcriptomics
2018/05/21 by Xiujun Sun, Zhihong Liu, Biao Wu +4 · 1 citation
Medicine · Biochemistry, Genetics and Molecular Biology · Environmental Science · #Cardiomyopathy and Myosin Studies #Muscle Physiology and Disorders #Marine Bivalve and Aquaculture Studies #Myosin #Adductor muscles #Biology #Myofibril #Transcriptome #Scallop #Sarcomere #Titin #Proteomics #Cell biology #Myocyte #Proteome #Myosin light-chain kinase #Gene expression #Biochemistry #Gene #Anatomy #Fishery
- Role of smooth muscle cells in coronary artery bypass grafting failure
2018/01/22 by Kerry Wadey, Kerry S. Wadey, Joshua Lopes +4 · 26 citations
Medicine · #Artery #Bypass grafting #Cardiac Fibrosis and Remodeling #Cardiac Ischemia and Reperfusion #Cardiac and Coronary Surgery Techniques #Cardiology #Heart failure #Internal medicine #Medicine #Myocyte
- Skeletal muscle inflammation and insulin resistance in obesity
2017/01/02 by Huaizhu Wu, Christie M. Ballantyne · 29 citations
Medicine · #Adipokines, Inflammation, and Metabolic Diseases #Adipose Tissue and Metabolism #Adipose tissue #Biology #Carbohydrate metabolism #Cardiovascular Disease and Adiposity #Endocrinology #Glucose homeostasis #Glucose uptake #Inflammation #Insulin #Insulin resistance #Internal medicine #Medicine #Myocyte #Proinflammatory cytokine #Skeletal muscle
- Triadin and CLIMP-63 form a link between triads and microtubules in muscle cells
2016/08/26 by Alexis Osseni, Muriel Sébastien, Oriana Sarrault +6 · 20 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Adipose Tissue and Metabolism #Anatomy #Biology #Cell biology #Combinatorics #Link (geometry) #Microtubule #Mitochondrial Function and Pathology #Muscle Physiology and Disorders #Myocyte
- Inositol 1,4,5-trisphosphate-mediated sarcoplasmic reticulum–mitochondrial crosstalk influences adenosine triphosphate production via mitochondrial Ca2+uptake through the mitochondrial ryanodine receptor in cardiac myocytes
2016/08/05 by Lea K. Seidlmayer, Johannes Kühn, Johannes Kuhn +11 · 25 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Adenosine triphosphate #Biochemistry #Biology #Cardiac Ischemia and Reperfusion #Cardiovascular Function and Risk Factors #Cell biology #Chemistry #Cytosol #Endocrinology #Endoplasmic reticulum #Inositol #Inositol trisphosphate receptor #Internal medicine #Medicine #Mitochondrial Function and Pathology #Mitochondrial permeability transition pore #Mitochondrion #Myocyte #Receptor #Ryanodine receptor #Uniporter
- Effects of 1,25(OH)2D3and 25(OH)D3on C2C12 Myoblast Proliferation, Differentiation, and Myotube Hypertrophy
2016/03/28 by K. van der Meijden, N. Bravenboer, Nathalie Bravenboer +14 · 21 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Biology #C2C12 #Cardiomyopathy and Myosin Studies #Cell biology #Chemistry #Endocrinology #Muscle Physiology and Disorders #Muscle hypertrophy #Muscle metabolism and nutrition #Myocyte #Myogenesis
- Myomir dysregulation and reactive oxygen species in aged human satellite cells
2016/03/11 by Ester Sara Di Filippo, Rosa Mancinelli, Tiziana Pietrangelo +4 · 21 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Biochemistry #Biology #Cell biology #Endocrinology #Gene #Homeostasis #Muscle Physiology and Disorders #Myocyte #Myogenesis #Nutrition and Health in Aging #Reactive oxygen species #Regeneration (biology) #Sarcopenia #Satellite #Skeletal muscle #Telomeres, Telomerase, and Senescence #microRNA
- Supra-physiological dose of testosterone induces pathological cardiac hypertrophy
2016/02/05 by Prapawadee Pirompol, Vassana Teekabut, Wattana Weerachatyanukul +3 · 20 citations
Agricultural and Biological Sciences · Medicine · #Androgen #Cardiac function curve #Endocrinology #Heart failure #Hormonal and reproductive studies #Hormone #Internal medicine #Medicine #Muscle hypertrophy #Myocyte #Myofilament #Pharmacological Effects and Assays #Testosterone (patch)
- Nano-imaging of the beating mouse heart in vivo: Importance of sarcomere dynamics, as opposed to sarcomere length per se, in the regulation of cardiac function
2015/12/28 by Fuyu Kobirumaki-Shimozawa, Kotaro Oyama, Togo Shimozawa +6 · 26 citations
Medicine · #Anatomy #Biology #Blood pressure #Cardiac cycle #Cardiac electrophysiology and arrhythmias #Cardiology #Cardiomyopathy and Myosin Studies #Cardiovascular Function and Risk Factors #Circulatory system #Contraction (grammar) #Diastole #Dynamics (music) #In vivo #Internal medicine #Medicine #Myocyte #Physics #Sarcomere #Systole
- Historical perspective on heart function: the Frank–Starling Law
2015/11/19 by Vasco Sequeira, Jolanda van der Velden · 1 citation
Medicine · Neuroscience · #Artificial intelligence #Biology #Cardiac function curve #Cardiac muscle #Cardiology #Cardiomyopathy and Myosin Studies #Cardiovascular Effects of Exercise #Cardiovascular Function and Risk Factors #Computer science #Ejection fraction #Frank–Starling law of the heart #Heart failure #Internal medicine #Law #Law and economics #Medicine #Myocyte #Neuroscience #Perspective (graphical) #Political science #Sarcomere #Sociology #Starling #Stroke volume
- Ablation of HRC alleviates cardiac arrhythmia and improves abnormal Ca handling in CASQ2 knockout mice prone to CPVT
2015/09/25 by Bin Liu, Hsiang‐Ting Ho, Hsiang-Ting Ho +14 · 10 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Biochemistry #Biology #Blood pressure #Calsequestrin #Cardiac electrophysiology and arrhythmias #Cardiac function curve #Catecholaminergic polymorphic ventricular tachycardia #Cell biology #Chemistry #Diastole #Endocrinology #Endoplasmic Reticulum Stress and Disease #Endoplasmic reticulum #Heart failure #Internal medicine #Ion channel regulation and function #Knockout mouse #Medicine #Myocyte #Phenotype #Receptor #Refractory period #Ryanodine receptor #Ryanodine receptor 2
- Human Engineered Heart Muscles Engraft and Survive Long Term in a Rodent Myocardial Infarction Model
2015/09/02 by Johannes Riegler, Malte Tiburcy, Antje Ebert +16 · 26 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Andrology #Biology #Bioluminescence imaging #Cardiology #Cell biology #Cell culture #Ejection fraction #Heart failure #Heart transplantation #Internal medicine #Ischemia #Luciferase #Medicine #Mesenchymal stem cell research #Myocardial infarction #Myocyte #Pluripotent Stem Cells Research #Stem cell #Tissue Engineering and Regenerative Medicine #Transfection #Transplantation #Ventricular remodeling #Xenotransplantation
- Sarcomere length nanometry in rat neonatal cardiomyocytes expressed with α-actinin–AcGFP in Z discs
2014/03/17 by Seine A. Shintani, Kotaro Oyama, Fuyu Kobirumaki-Shimozawa +3 · 22 citations
Chemistry · Medicine · #Actinin #Anatomy #Biology #Cardiac electrophysiology and arrhythmias #Cardiomyopathy and Myosin Studies #Cardiovascular Effects of Exercise #Cell #Cell biology #Chemistry #Cytoskeleton #Genetics #Myocyte #Sarcomere
- Blockade of sarcolemmal TRPV2 accumulation inhibits progression of dilated cardiomyopathy
2013/06/19 by Yuko Iwata, Hitomi Ohtake, Osamu Suzuki +3 · 25 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · Neuroscience · #Cardiac electrophysiology and arrhythmias #Cardiology #Cardiomyopathy #Chemistry #Dilated cardiomyopathy #Endocrinology #Heart failure #Internal medicine #Ion Channels and Receptors #Ion channel regulation and function #Medicine #Myocyte #Pharmacology #Sarcolemma
- L-type calcium channel targeting and local signalling in cardiac myocytes
2013/02/14 by Robin M. Shaw, Henry M. Colecraft · 25 citations
Biochemistry, Genetics and Molecular Biology · Medicine · Neuroscience · #Biochemistry #Biology #Biophysics #Calcium #Calcium signaling #Cardiac action potential #Cardiac electrophysiology and arrhythmias #Cardiomyopathy and Myosin Studies #Cav1.2 #Cell biology #Electrophysiology #Endoplasmic reticulum #Internal medicine #Ion channel regulation and function #L-type calcium channel #Lipid microdomain #Medicine #Membrane #Myocyte #Neuroscience #Ryanodine receptor #Signal transduction #Voltage-dependent calcium channel
- Functional studies of the Ciona intestinalis myogenic regulatory factor reveal conserved features of chordate myogenesis
2013/02/04 by Stephanie A. Izzi, Bonnie J. Colantuono, Bonnie Colantuono +3 · 7 citations
Biochemistry, Genetics and Molecular Biology · Engineering · Environmental Science · #Biology #Cell biology #Chordate #Ciona #Ciona intestinalis #Computational biology #Conserved sequence #Developmental Biology and Gene Regulation #Embryogenesis #Gene #Genetics #Marine Biology and Environmental Chemistry #Marine Ecology and Invasive Species #Myocyte #Myogenesis #Notochord #Peptide sequence #Vertebrate
- The tension mounts: Stress fibers as force-generating mechanotransducers
2013/01/07 by Keith Burridge, Erika S. Wittchen · 28 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Actin #Anatomy #Biology #Biophysics #Cell #Cell biology #Cellular Mechanics and Interactions #Composite material #Cytoskeleton #Erythrocyte Function and Pathophysiology #Genetics #Materials science #Mechanosensitive channels #Myocyte #Myosin #Sarcomere #Skin and Cellular Biology Research #Stress fiber #Structural engineering #Tensegrity #Tension (geology) #Ultimate tensile strength
- Regulation of MEF2 transcriptional activity by calcineurin/mAKAP complexes
2012/12/21 by Jinliang Li, Maximilian A.X. Vargas, Michael S. Kapiloff +2 · 27 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Biochemistry #Biology #Calcineurin #Cell biology #Enhancer #Gene #Histone Deacetylase Inhibitors Research #Internal medicine #MEF2C #Mef2 #Molecular biology #Myocyte #NFAT #Peptidase Inhibition and Analysis #Phosphatase #Phosphorylation #Signaling Pathways in Disease #Transcription factor #Transplantation
- Cigarette smoke and muscle catabolism in C2 myotubes
2012/12/21 by Oren Rom, Sharon Kaisari, Dror Aizenbud +1 · 1 citation
Biochemistry, Genetics and Molecular Biology · Chemistry · Materials Science · Medicine · #Biology #Catabolism #Cell biology #Chemistry #Endocrinology #Internal medicine #Kinase #MAPK/ERK pathway #Medicine #Metabolism #Muscle Physiology and Disorders #Muscle atrophy #Muscle metabolism and nutrition #Myocyte #Myogenesis #Myosin #Oxidative stress #Protein degradation #Sarcopenia #Skeletal muscle #biodegradable polymer synthesis and properties #p38 mitogen-activated protein kinases
- Calcium-mediated cell death during myocardial reperfusion
2012/04/11 by D. Garcia-Dorado, David García‐Dorado, Marisol Ruiz‐Meana +6 · 27 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Apoptosis #Biochemistry #Biology #Calcium #Calcium in biology #Calpain #Cardiac Ischemia and Reperfusion #Cardiac electrophysiology and arrhythmias #Cell biology #Chemistry #Cytosol #Endoplasmic reticulum #Internal medicine #Intracellular #Ischemia #Medicine #Mitochondrial Function and Pathology #Mitochondrial permeability transition pore #Myocyte #Programmed cell death #Reperfusion injury #Reperfusion therapy
- Growth and the regulation of myotomal muscle mass in teleost fish
2011/04/27 by Ian A. Johnston, Neil I. Bower, Daniel J. Macqueen · 27 citations
Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · Environmental Science · #Anatomy #Aquaculture Nutrition and Growth #Biology #Cell biology #Embryo #Embryogenesis #Muscle Physiology and Disorders #Myocyte #Myogenesis #Physiological and biochemical adaptations #Skeletal muscle
- Impact of Sarcoplasmic Reticulum Calcium Release on Calcium Dynamics and Action Potential Morphology in Human Atrial Myocytes: A Computational Study
2011/01/27 by Jussi T. Koivumäki, Topi Korhonen, Pasi Tavi · 1 citation
Medicine · Biochemistry, Genetics and Molecular Biology · Neuroscience · Chemistry · #Cardiac electrophysiology and arrhythmias #Ion channel regulation and function #Neuroscience and Neural Engineering #Endoplasmic reticulum #Calcium #Myocyte #Intracellular #Biophysics #Calcium in biology #Electrophysiology #Chemistry #Contraction (grammar) #Internal medicine #Atrial myocytes #Biology #Medicine #Biochemistry
- α-Skeletal muscle actin nemaline myopathy mutants cause cell death in cultured muscle cells
2009/04/22 by Drieke Vandamme, Ellen Lambert, Davy Waterschoot +6 · 1 citation
Biochemistry, Genetics and Molecular Biology · Medicine · Neuroscience · #Actin #Anatomy #Biology #Biopsy #Bleb (medicine) #Cardiomyopathy and Myosin Studies #Cell biology #Congenital myopathy #Genetic Neurodegenerative Diseases #Medicine #Muscle Physiology and Disorders #Muscle biopsy #Muscle weakness #Myocyte #Myofilament #Myogenesis #Nebulin #Nemaline myopathy #Neuroscience #Pathology #Sarcomere #Skeletal muscle #Titin
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