Functional studies of the Ciona intestinalis myogenic regulatory factor reveal conserved features of chordate myogenesis

2013/02/04 by Stephanie A. Izzi, Bonnie J. Colantuono, Bonnie Colantuono +3 · 7 citations
Biochemistry, Genetics and Molecular Biology · Engineering · Environmental Science · #Biology #Cell biology #Chordate #Ciona #Ciona intestinalis #Computational biology #Conserved sequence #Developmental Biology and Gene Regulation #Embryogenesis #Gene #Genetics #Marine Biology and Environmental Chemistry #Marine Ecology and Invasive Species #Myocyte #Myogenesis #Notochord #Peptide sequence #Vertebrate

paper · doi:10.1016/j.ydbio.2013.01.033

openalex publication_date 2013/02/04 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/01

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• The Ciona myogenic regulatory factor functions as a typical MRF but possesses a novel N-terminus that is essential for activity. [europepmc]
• Regulation and evolution of muscle development in tunicates. [europepmc]
• More Than One-to-Four via 2R: Evidence of an Independent Amphioxus Expansion and Two-Gene Ancestral Vertebrate State for MyoD-Related Myogenic Regulatory Factors (MRFs). [europepmc]
• Exon skipping in genes encoding lineage-defining myogenic transcription factors in rhabdomyosarcoma. [europepmc]
• Quantitative proteome dynamics across embryogenesis in a model chordate. [europepmc]
• A change in cis-regulatory logic underlying obligate versus facultative muscle multinucleation in chordates. [europepmc]