Actin-Depolymerizing Factor and Cofilin-1 Have Unique and Overlapping Functions in Regulating Intestinal Epithelial Junctions and Mucosal Inflammation

2016/02/14 by Dongdong Wang, Nayden G. Naydenov, Alex Feygin +3 · 24 citations
Biochemistry, Genetics and Molecular Biology · Medicine · Neuroscience · #Cellular Mechanics and Interactions #Cell Adhesion Molecules Research #Barrier Structure and Function Studies

paper · pdf · doi:10.1016/j.ajpath.2015.11.023

Cited by

• Disruption of the epithelial barrier during intestinal inflammation: Quest for new molecules and mechanisms
• Disruption of the epithelial barrier during intestinal inflammation: Quest for new molecules and mechanisms. [europepmc]
• Shigella depends on SepA to destabilize the intestinal epithelial integrity via cofilin activation. [europepmc]
• cAMP-dependent activation of protein kinase A attenuates respiratory syncytial virus-induced human airway epithelial barrier disruption. [europepmc]
• Decreased TESK1-mediated cofilin 1 phosphorylation in the jejunum of IBS-D patients may explain increased female predisposition to epithelial dysfunction. [europepmc]
• Modulation of Intestinal Paracellular Transport by Bacterial Pathogens. [europepmc]
• EGF receptor plays a role in the mechanism of glutamine-mediated prevention of alcohol-induced gut barrier dysfunction and liver injury. [europepmc]
• Sperm Flagellar 1 Binds Actin in Intestinal Epithelial Cells and Contributes to Formation of Filopodia and Lamellipodia. [europepmc]
• A Septin Cytoskeleton-Targeting Small Molecule, Forchlorfenuron, Inhibits Epithelial Migration via Septin-Independent Perturbation of Cellular Signaling. [europepmc]
• Sensing Actin Dynamics through Adherens Junctions. [europepmc]
• Impact of in ovo administered pioneer colonizers on intestinal proteome on day of hatch. [europepmc]
• A Novel Pharmacological Approach to Enhance the Integrity and Accelerate Restitution of the Intestinal Epithelial Barrier. [europepmc]
• The HIF target ATG9A is essential for epithelial barrier function and tight junction biogenesis. [europepmc]
• Actin cytoskeleton dynamics during mucosal inflammation: a view from broken epithelial barriers. [europepmc]
• The Intestinal Barrier and Current Techniques for the Assessment of Gut Permeability. [europepmc]
• PARK7 Diminishes Oxidative Stress-Induced Mucosal Damage in Celiac Disease. [europepmc]
• Loss of β-Cytoplasmic Actin in the Intestinal Epithelium Increases Gut Barrier Permeability in vivo and Exaggerates the Severity of Experimental Colitis. [europepmc]
• Mucin-2 knockout is a model of intercellular junction defects, mitochondrial damage and ATP depletion in the intestinal epithelium. [europepmc]
• Mechanotransduction in Skin Inflammation. [europepmc]
• Understanding disruption of the gut barrier during inflammation: Should we abandon traditional epithelial cell lines and switch to intestinal organoids? [europepmc]
• Regulation of Epithelial and Endothelial Barriers by Molecular Chaperones. [europepmc]
• Rationally designed probiotics prevent shrimp white feces syndrome via the probiotics-gut microbiome-immunity axis. [europepmc]
• Coactosin-like protein 1 regulates integrity and repair of model intestinal epithelial barriers via actin binding dependent and independent mechanisms. [europepmc]
• The application of explants, crypts, and organoids as models in intestinal barrier research. [europepmc]