- The role of intra and inter-molecular disulfide bonds in modulating amyloidogenesis: A review
2021/12/24 by Aranyak Mitra, Nandini Sarkar · 8 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Alzheimer's disease research and treatments #Amyloid (mycology) #Amyloid fibril #Amyloid β #Biochemistry #Biology #Biophysics #Chemistry #Disease #Disulfide bond #Endoplasmic Reticulum Stress and Disease #Fibril #Internal medicine #Medicine #Prion Diseases and Protein Misfolding #Protein aggregation #Protein folding
- The monomers, oligomers, and fibrils of amyloid-β inhibit the activity of mitoBKCa channels by a membrane-mediated mechanism
2020/05/04 by Yevheniia Kravenska, Hanna Nieznańska, Hanna Nieznanska +6 · 17 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Materials Science · Medicine · #Alzheimer's disease research and treatments #Amyloid (mycology) #Biochemistry #Biology #Biophysics #Chemistry #Fibril #Ion channel #Lipid Membrane Structure and Behavior #Lipid bilayer #Mechanosensitive channels #Membrane #Monomer #Peptide #Supramolecular Self-Assembly in Materials
- Food protein amyloid fibrils: Origin, structure, formation, characterization, applications and health implications
2019/05/10 by Yiping Cao, Raffaele Mezzenga · 32 citations
Agricultural and Biological Sciences · Chemistry · Materials Science · Medicine · #Alzheimer's disease research and treatments #Amyloid (mycology) #Amyloid fibril #Amyloid β #Biochemistry #Bioinformatics #Biology #Biomedicine #Biophysics #Characterization (materials science) #Chemistry #Context (archaeology) #Disease #Fibril #Food protein #Human health #Materials science #Medicine #Nanotechnology #Pathology #Pickering emulsions and particle stabilization #Protein aggregation #Proteins in Food Systems
- Macrophage-Mediated Phagocytosis and Dissolution of Amyloid-Like Fibrils in Mice, Monitored by Optical Imaging
2019/02/05 by Tina Richey, James S. Foster, Angela D. Williams +14 · 12 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Alzheimer's disease research and treatments #Amyloid (mycology) #Amyloidosis #Amyloidosis: Diagnosis, Treatment, Outcomes #Biochemistry #Biology #Biophysics #Cell biology #Chemistry #Congo red #Dermatological and Skeletal Disorders #Extracellular #Fibril #Innate immune system #Medicine #Pathology #Phagocytosis
- Alpha-synuclein fibrils recruit TBK1 and OPTN to lysosomal damage sites and induce autophagy in microglial cells
2018/11/07 by Claudio Bussi, Javier María Peralta Ramos, Javier M. Peralta Ramos +12 · 26 citations
Medicine · #Alpha-synuclein #Alzheimer's disease research and treatments #Apoptosis #Autophagy #Autophagy in Disease and Therapy #Biochemistry #Biology #Cell biology #Fibril #Immunology #Inflammation #Microglia #Parkinson's Disease Mechanisms and Treatments #Parkinson's disease #Pathology
- Amyloid assembly and disassembly
2018/04/13 by Edward Chuang, Acacia M. Hori, Acacia M Hori +2 · 25 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Alzheimer's disease research and treatments #Amyloid (mycology) #Amyloid disease #Amyloid fibril #Amyloid β #Amyotrophic Lateral Sclerosis Research #Autophagy #Biochemistry #Biogenesis #Biology #Cell biology #Disease #Fibril #Internal medicine #Medicine #Prion Diseases and Protein Misfolding #Proteasome #Protein aggregation #Protein folding
- Propagation of Tau aggregates
2017/05/30 by Michel Goedert, Maria Grazia Spillantini · 1 citation
Medicine · Biochemistry, Genetics and Molecular Biology · Neuroscience · Chemistry · #Alzheimer's disease research and treatments #Prion Diseases and Protein Misfolding #Neurological diseases and metabolism #Fibril #Neurodegeneration #Prion protein #Protein aggregation #Biophysics #Chemistry #Tau protein #Neuroscience #Amyloid fibril #Amyloid β #Biology #Disease #Biochemistry #Alzheimer's disease #Medicine #Pathology
- Coherent X-Ray Imaging of Collagen Fibril Distributions within Intact Tendons
2014/01/01 by Felisa Berenguer, Richard Bean, Richard J. Bean +11 · 2 citations
Chemistry · Physics and Astronomy · #Advanced X-ray Imaging Techniques #Anatomy #Biology #Biophysics #Characterization (materials science) #Chemistry #Collagen fibril #Composite material #Computer science #Crystallography #Fibril #Laser-Plasma Interactions and Diagnostics #Materials science #Nanometre #Nanotechnology #Optics #Physics #Resolution (logic) #Ultrastructure
- ATR-FTIR: A “rejuvenated” tool to investigate amyloid proteins
2013/06/05 by Rabia Sarroukh, Erik Goormaghtigh, Jean-Marie Ruysschaert +2 · 28 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Alzheimer's disease research and treatments #Amyloid (mycology) #Amyloid fibril #Amyloid β #Biochemistry #Biology #Biophysics #Chemical engineering #Chemistry #Disease #Fibril #Fourier transform infrared spectroscopy #Medicine #Metabolomics and Mass Spectrometry Studies #Oligomer #Organic chemistry #Peptide #Protein Structure and Dynamics #Protein aggregation
- Protein fibrillation and the olfactory system: speculations on their linkage
2012/09/19 by Morteza Mahmoudi, Kenneth S. Suslick · 1 citation
Chemistry · Medicine · Neuroscience · Nursing · #Alzheimer's disease research and treatments #Amyloid (mycology) #Biochemical Analysis and Sensing Techniques #Biochemistry #Bioinformatics #Biology #Biophysics #Chemistry #Computational biology #Fibril #Medicine #Neuroscience #Pathology #Protein folding #Trace Elements in Health
- Rationally Designed Turn Promoting Mutation in the Amyloid-β Peptide Sequence Stabilizes Oligomers in Solution
2011/07/22 by Jayakumar Rajadas, Corey W. Liu, Paul Novick +4 · 2 citations
Medicine · Biochemistry, Genetics and Molecular Biology · Mathematics · Chemistry · #Alzheimer's disease research and treatments #Protein Structure and Dynamics #Graph theory and applications #Oligomer #Peptide #Fibril #Amyloid (mycology) #Biophysics #P3 peptide #Chemistry #Protein structure #Mutant #Amyloid beta #Turn (biochemistry) #Peptide sequence #Molecular dynamics #Biochemistry #Alzheimer's disease #Biology #Amyloid precursor protein #Medicine #Disease #Organic chemistry
- Environmental Conditions Affect the Kinetics of Nucleation of Amyloid Fibrils and Determine Their Morphology
2010/12/01 by Bertrand Morel, Lorena Varela, Ana I. Azuaga +2 · 25 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Materials Science · Medicine · #Alzheimer's disease research and treatments #Amyloid (mycology) #Amyloid fibril #Amyloid β #Biochemistry #Biology #Biophysics #Chemistry #Crystallography #Enzyme Structure and Function #Fibril #Kinetics #Morphology (biology) #Nucleation #Protein Structure and Dynamics
- Tendon and ligament fibrillar crimps give rise to left‐handed helices of collagen fibrils in both planar and helical crimps
2010/01/08 by Marco Franchi, Vittoria Ottani, Rita Stagni +1 · 15 citations
Materials Science · Medicine · #Anatomy #Biology #Biophysics #Collagen fibril #Collagen: Extraction and Characterization #Composite material #Crimp #Electron microscope #Fibril #Ligament #Materials science #Optics #Orthopedic Surgery and Rehabilitation #Tendon #Tendon Structure and Treatment
- Molecular and Mesoscale Mechanisms of Osteogenesis Imperfecta Disease in Collagen Fibrils
2009/07/31 by Alfonso Gautieri, Sebastien Uzel, Sebastien G. M. Uzel +3 · 1 citation
Biochemistry, Genetics and Molecular Biology · Chemistry · #Anatomy #Biology #Biophysics #Chemistry #Collagen fibril #Composite material #Connective tissue disorders research #Endocrinology #Fibril #Gene #Genetics #Intermolecular force #Materials science #Molecule #Mutation #Osteogenesis imperfecta #Phenotype #Point mutation #Stiffness #Type I collagen
- Sequence and Crowding Effects in the Aggregation of a 10-Residue Fragment Derived from Islet Amyloid Polypeptide
2009/05/29 by Eva Rivera, John E. Straub, John Straub +1 · 13 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Alzheimer's disease research and treatments #Amylin #Amyloid (mycology) #Amyloid fibril #Amyloid β #Biochemistry #Biology #Biophysics #Chemistry #Context (archaeology) #Crystallography #Dimer #Fibril #Insulin #Islet #Molecular dynamics #Nucleation #Peptide #Peptide sequence #Prion Diseases and Protein Misfolding #Protein Structure and Dynamics #Sequence (biology)
- Amyloid β-Protein Assembly and Alzheimer Disease
2008/10/10 by Robin Roychaudhuri, Mingfeng Yang, Minako Hoshi +1 · 1 citation
Medicine · Biochemistry, Genetics and Molecular Biology · Computer Science · Neuroscience · Chemistry · #Alzheimer's disease research and treatments #Prion Diseases and Protein Misfolding #Computational Drug Discovery Methods #Disease #Amyloid fibril #Protein folding #Amyloid (mycology) #Fibril #Biochemistry of Alzheimer's disease #P3 peptide #Neuroscience #Protein aggregation #Alzheimer's disease #Amyloid β #Chemistry #Medicine #Amyloid precursor protein #Biology #Pathology #Cell biology #Biochemistry
- Unraveling the mysteries of protein folding and misfolding
2008/09/02 by Heath Ecroyd, John A. Carver · 1 citation
Medicine · Biochemistry, Genetics and Molecular Biology · Chemistry · #Alzheimer's disease research and treatments #Prion Diseases and Protein Misfolding #Protein Structure and Dynamics #Fibril #Amyloid fibril #Protein folding #Protein aggregation #Chemistry #Amyloid (mycology) #Biophysics #Chaperone (clinical) #Heat shock protein #Folding (DSP implementation) #Biochemistry #Biology #Amyloid β #Medicine #Disease #Pathology
- Protein Aggregation in the Brain: The Molecular Basis for Alzheimer’s and Parkinson’s Diseases
2008/03/18 by G. Brent Irvine, Omar M. A. El‐Agnaf, Ganesh M. Shankar +1 · 1 citation
Medicine · Biochemistry, Genetics and Molecular Biology · Chemistry · Neuroscience · #Alzheimer's disease research and treatments #Parkinson's Disease Mechanisms and Treatments #Prion Diseases and Protein Misfolding #Protein aggregation #Fibril #Monomer #Amyloid fibril #Disease #Pathogenesis #Chemistry #Amyloid (mycology) #Neuroscience #Medicine #Biophysics #Amyloid β #Biology #Polymer #Biochemistry #Pathology
- Protein fibrils in nature can enhance amyloid protein A amyloidosis in mice: Cross-seeding as a disease mechanism
2005/04/13 by Katarzyna Lundmark, Gunilla T. Westermark, Arne Olsén +1 · 3 citations
Biochemistry, Genetics and Molecular Biology · Medicine · Chemistry · #Prion Diseases and Protein Misfolding #Amyloidosis: Diagnosis, Treatment, Outcomes #Alzheimer's disease research and treatments #Fibril #Amyloidosis #Amyloid (mycology) #Amyloid disease #Chemistry #Amyloid fibril #In vitro #Biochemistry #AA amyloidosis #Biophysics #Biology #Pathology #Medicine #Amyloid β #Disease
- The E46K Mutation in α-Synuclein Increases Amyloid Fibril Formation
2005/01/05 by Eric A. Greenbaum, Charles L. Graves, Amanda J. Mishizen-Eberz +5 · 30 citations
Chemistry · Medicine · #Alzheimer's disease research and treatments #Amyloid (mycology) #Amyloid fibril #Amyloid β #Biochemistry #Chemistry #Disease #Fibril #Gene #Medicine #Mutation #Neurological disorders and treatments #Parkinson's Disease Mechanisms and Treatments #Pathology
- Histological and Ultrastructural Evaluation of the Effects of a Radiofrequency-Based Nonablative Dermal Remodeling Device
2004/02/01 by Brian D. Zelickson, David Kist, David A. Kist +12 · 27 citations
Chemistry · Medicine · #Anatomy #Biology #Biophysics #Chemistry #Collagen fibril #Contraction (grammar) #Dermatologic Treatments and Research #Dermis #Electron microscope #Epidermis (zoology) #Fibril #Ground substance #Internal medicine #Medicine #Pathology #Tendon #Tendon Structure and Treatment #Ultrastructure #Western blot #Wound Healing and Treatments
- Discrete molecular dynamics simulations of peptide aggregation
2003/12/30 by Shuying Peng, S. Peng, F. Ding +11 · 2 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Materials Science · Physics and Astronomy · #Aggregate (composite) #BETA (programming language) #Beta sheet #Biochemistry #Biological system #Biology #Chain (unit) #Chemical physics #Chemistry #Computational chemistry #Computer science #Crystallography #Dynamics (music) #Enzyme Structure and Function #Fibril #Hydrogen bond #Materials science #Molecular dynamics #Molecule #Nanotechnology #Peptide #Physics #Protein Structure and Dynamics #Supramolecular Self-Assembly in Materials #cond-mat.soft #q-bio.BM