- A single residue in the yellow fever virus envelope protein modulates virion architecture and antigenicity
2025/09/26 by Summa Bibby, James Jung, Yu Shang Low +14 · 1 voice · 3 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Antigenicity #Flaviviridae #Flavivirus #Immunogenicity #Mosquito-borne diseases and control #Residue (chemistry) #Vibrio bacteria research studies #Viral Infections and Vectors #Viral envelope #Virulence #Virus #Yellow fever
- Vaccination with mRNA-encoded nanoparticles drives early maturation of HIV bnAb precursors in humans
2025/05/15 by Jordan R. Willis, Madhu Prabhakaran, Michelle K. Muthui +97 · 28 citations
Immunology and Microbiology · Medicine · #Antibody #B cell #Biology #Gene #Genetics #HIV Research and Treatment #HIV vaccine #HIV/AIDS Research and Interventions #Heterologous #Immunogen #Immunogenicity #Immunology #Immunotherapy and Immune Responses #Monoclonal antibody #Priming (agriculture) #Somatic hypermutation #Vaccination #Vaccine trial #Virology
- Nanomedicines for an Enhanced Immunogenic Cell Death-Based In Situ Cancer Vaccination Response
2024/02/28 by Caiyan Zhao, Changrong Wang, Wenbo Shan +3 · 16 citations
Engineering · Immunology and Microbiology · Medicine · #Antigen #Antigenicity #Cancer immunotherapy #Cancer research #Cancer vaccine #Immune system #Immunogenic cell death #Immunogenicity #Immunology #Immunotherapy #Immunotherapy and Immune Responses #Medicine #Nanoplatforms for cancer theranostics #Phagocytosis and Immune Regulation #Tumor microenvironment
- Chemical and biological conjugation strategies for the development of multivalent protein vaccine nanoparticles
2023/07/25 by Jaeyoung Park, Thomas Pho, Julie A. Champion · 8 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Immunology and Microbiology · Medicine · #Antigen #Biochemistry #Biology #Cell biology #Chemistry #Fusion protein #Immune system #Immunogenicity #Immunology #Immunotherapy and Immune Responses #Monoclonal and Polyclonal Antibodies Research #Protein subunit #Recombinant DNA #vaccines and immunoinformatics approaches
- Non-glycosylated SARS-CoV-2 RBD elicited a robust neutralizing antibody response in mice
2022/05/06 by Qian Ke, Peng Sun, Tiantian Wang +4 · 7 citations
Agricultural and Biological Sciences · Chemistry · Medicine · #Animal Virus Infections Studies #Antibody #Biochemistry #Biology #Chemistry #Escherichia coli #Gene #Immune system #Immunity #Immunogenicity #Immunology #Microbiology #Neutralization #Neutralizing antibody #Recombinant DNA #SARS-CoV-2 and COVID-19 Research #Viral gastroenteritis research and epidemiology #Virology #Virus
- Immunogenicity of Recombinant-Deficient Lactobacillus casei with Complementary Plasmid Expressing Alanine Racemase Gene and Core Neutralizing Epitope Antigen against Porcine Epidemic Diarrhea Virus
2021/09/26 by Fengsai Li, Xiaona Wang, Xiaolong Fan +8 · 1 voice · 4 citations
Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · Medicine · #Animal Virus Infections Studies #Antibody #Antigen #Bacteria #Biology #Epitope #Gene #Immune system #Immunogenicity #Immunology #Lactobacillus casei #Microbiology #Plasmid #Porcine epidemic diarrhea virus #Recombinant DNA #Viral gastroenteritis research and epidemiology #Virology #Virus #Virus-based gene therapy research
- Safety and immunogenicity of a single dose of a tetravalent dengue vaccine with two different serotype-2 potencies in adults in Singapore: A phase 2, double-blind, randomised, controlled trial
2019/12/13 by Vianney Tricou, Jenny G. Low, Helen M. Oh +13 · 22 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Antibody #Biological Research and Disease Studies #Dengue fever #Dengue vaccine #Dengue virus #Immunogenicity #Immunology #Internal medicine #Medicine #Mosquito-borne diseases and control #Randomized controlled trial #Serostatus #Viral Infections and Outbreaks Research #Viral load
- Endolysins as emerging alternative therapeutic agents to counter drug-resistant infections
2019/11/09 by Vijay Singh Gondil, Kusum Harjai, Sanjay Chhibber · 28 citations
Agricultural and Biological Sciences · Environmental Science · Medicine · #Antibiotic resistance #Antibiotics #Bacteria #Bacteriophage #Bacteriophages and microbial interactions #Biology #Computational biology #Drug #Drug resistance #Escherichia coli #Genetics #Immune system #Immunogenicity #Immunology #Lysin #Lytic cycle #Microbiology #Peptidoglycan #Pharmacology #Plant Virus Research Studies #Viral gastroenteritis research and epidemiology #Virology #Virus
- Therapeutic efficacy of a human papillomavirus type 16 E7 bacterial exotoxin fusion protein adjuvanted with CpG or GPI-0100 in a preclinical mouse model for HPV-associated disease
2019/04/19 by Diane M. Da Silva, Joseph G. Skeate, Elena Chavez-Juan +6 · 15 citations
Immunology and Microbiology · Medicine · #Adjuvant #Biology #Cancer research #CpG Oligodeoxynucleotide #Fusion protein #Gene #Immune system #Immunogenicity #Immunology #Immunotherapy and Immune Responses #Medicine #Microbial infections and disease research #Recombinant DNA #TLR9 #Toxin Mechanisms and Immunotoxins #Virology
- Chitosan for gene delivery: Methods for improvement and applications
2019/03/21 by Di Chuan, Tao Jin, Rangrang Fan +2 · 26 citations
Biochemistry, Genetics and Molecular Biology · #Advanced biosensing and bioanalysis techniques #Biochemistry #Biology #Chitosan #Computational biology #Delivery system #Gene #Gene delivery #Genetic enhancement #Genetics #Immune system #Immunogenicity #Immunology #Materials science #Nanotechnology #Pharmacology #RNA Interference and Gene Delivery #Recombinant DNA #Vector (molecular biology) #Viral vector #Virus-based gene therapy research
- Exposure to wild-type AAV drives distinct capsid immunity profiles in humans
2018/10/22 by Klaudia Kuranda, Priscilla Jean-Alphonse, Christian Leborgne +8 · 26 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Antibody #Biology #CD8 #Capsid #Genetics #Herpesvirus Infections and Treatments #Humoral immunity #Immune system #Immunity #Immunogenicity #Immunology #In vitro #Medicine #Peripheral blood mononuclear cell #Population #RNA Interference and Gene Delivery #Transduction (biophysics) #Virology #Virus #Virus-based gene therapy research
- A phase 1 study of safety and immunogenicity following intradermal administration of a tetravalent dengue vaccine candidate
2018/05/19 by Lisa A. Jackson, Richard Rupp, Athanasia Papadimitriou +4 · 19 citations
Immunology and Microbiology · Medicine · #Adverse effect #Antibody #Dengue fever #Dengue vaccine #Dengue virus #Immunization #Immunogenicity #Immunology #Internal medicine #Medicine #Mosquito-borne diseases and control #Neutralizing antibody #Placebo #Poxvirus research and outbreaks #Seroconversion #Serotype #Titer #Vaccination #Vaccination schedule #Viral Infections and Outbreaks Research #Virology
- CMV specific cytokine release assay in whole blood is optimized by combining synthetic CMV peptides and toll like receptor agonists
2014/10/30 by Werner Dammermann, David Bochmann, Frank Bentzien +5 · 7 citations
Medicine · #Antibody #Antigen #Biochemistry #Biology #Cytomegalovirus and herpesvirus research #Immune system #Immunogenicity #Immunology #Lipoteichoic acid #Molecular biology #Recombinant DNA #Staphylococcus aureus #Systemic Lupus Erythematosus Research #Viral Infections and Immunology Research #Virology
- Mouse Model of Devil Facial Tumour Disease Establishes That an Effective Immune Response Can be Generated Against the Cancer Cells
2014/05/27 by Terry L. Pinfold, Gabriella K. Brown, SS Bettiol +1 · 1 citation
Medicine · Biochemistry, Genetics and Molecular Biology · Veterinary · #Veterinary Oncology Research #Virus-based gene therapy research #Infectious Diseases and Mycology #Immune system #Immunogenicity #Biology #Antibody #Population #Immunology #Immunity #Medicine
- Recommendations for the characterization of immunogenicity response to multiple domain biotherapeutics
2014/05/24 by Boris Gorovits, Eric Wakshull, Renuka Pillutla +3 · 15 citations
Immunology and Microbiology · Medicine · #Antibody #Biology #Biosimilars and Bioanalytical Methods #CAR-T cell therapy research #Computational biology #Computer science #Immunogenicity #Immunology #Medicine #Monoclonal and Polyclonal Antibodies Research #Polyclonal antibodies
- T cells induced by recombinant chimpanzee adenovirus alone and in prime‐boost regimens decrease chimeric EcoHIV/NDK challenge virus load
2012/08/29 by Yaowaluck Roshorm, Yaowaluck Maprang Roshorm, Mathew G. Cottingham +4 · 11 citations
Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · #AIDS Vaccines #Antigen #Biology #DNA vaccination #Epitope #Gene #Genetics #HIV Research and Treatment #Immune system #Immunization #Immunogenicity #Immunology #Immunotherapy and Immune Responses #Modified vaccinia Ankara #Plasmid #Recombinant DNA #Recombineering #Vaccination #Vaccine trial #Vaccinia #Virology #Virus #Virus-based gene therapy research
- Improved CD4+ T cell responses to Mycobacterium tuberculosis in PPD-negative adults by M72/AS01 as compared to the M72/AS02 and Mtb72F/AS02 tuberculosis candidate vaccine formulations: A randomized trial
2012/05/27 by Isabel Leroux-Roels, Isabel Leroux‐Roels, Sheron Forgus +12 · 26 citations
Immunology and Microbiology · Medicine · #Adjuvant #Immune responses and vaccinations #Immune system #Immunodeficiency and Autoimmune Disorders #Immunogenicity #Immunology #Medicine #Mycobacterium tuberculosis #Pathology #Reactogenicity #Tuberculosis #Tuberculosis Research and Epidemiology #Tuberculosis vaccines
- Immunogenicity and efficacy of chimeric dengue vaccine (DENVax) formulations in interferon-deficient AG129 mice
2011/12/13 by Joseph N. Brewoo, Richard M. Kinney, Tim D. Powell +8 · 25 citations
Medicine · #Antibody #Biology #Context (archaeology) #Dengue fever #Dengue vaccine #Dengue virus #Gene #Genetics #Heterologous #Immunogenicity #Immunology #Microbiology #Mosquito-borne diseases and control #Neutralizing antibody #Serotype #Viral Infections and Outbreaks Research #Viral Infections and Vectors #Viremia #Virology #Virus
- Development of DENVax: A chimeric dengue-2 PDK-53-based tetravalent vaccine for protection against dengue fever
2011/07/25 by Jorge E. Osorio, Claire Y.-H. Huang, Claire Y.‐H. Huang +2 · 26 citations
Medicine · #Antibody #Biology #Dengue fever #Dengue vaccine #Dengue virus #Flaviviridae #Immunogenicity #Immunology #Mosquito-borne diseases and control #Viral Infections and Outbreaks Research #Viral Infections and Vectors #Viral disease #Virology #Virus
- Biological significance of amino acid substitutions in hepatitis B surface antigen (HBsAg) for glycosylation, secretion, antigenicity and immunogenicity of HBsAg and hepatitis B virus replication
2009/10/07 by C. Wu, Chunli Wu, X. Zhang +11 · 26 citations
Immunology and Microbiology · Medicine · #Antigen #Antigenicity #Biology #Epitope #HBsAg #Hepatitis B Virus Studies #Hepatitis B virus #Hepatitis C virus research #Immunogenicity #Immunology #Immunotherapy and Immune Responses #Molecular biology #Virology #Virus
- Safety and immunogenicity of a prototype adjuvanted inactivated split-virus influenza A (H5N1) vaccine in infants and children
2008/09/17 by Terry Nolan, Peter C. Richmond, Peter Richmond +16 · 27 citations
Medicine · #Adjuvant #Adverse effect #Antibody #Hemagglutination assay #Immunogenicity #Immunology #Inactivated vaccine #Influenza A virus #Influenza A virus subtype H5N1 #Influenza Virus Research Studies #Internal medicine #Medicine #Respiratory viral infections research #Titer #Tolerability #Vaccination #Virology #Virology and Viral Diseases #Virus
- Enhanced immunogenicity of HPV16E7 accompanied by Gp96 as an adjuvant in two vaccination strategies
2008/04/19 by Azam Bolhassani, Farnaz Zahedifard, Mohammad Taghikhani +1 · 14 citations
Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · Medicine · #Adjuvant #Biology #DNA vaccination #Gene #Genetics #Heat shock protein #Hepatitis B Virus Studies #Humoral immunity #Immune system #Immunization #Immunogenicity #Immunology #Immunotherapy and Immune Responses #Vaccination #Virology #Virus-based gene therapy research
- Recommendations on risk-based strategies for detection and characterization of antibodies against biotechnology products
2008/01/30 by Eugen Koren, Holly W. Smith, Elizabeth Shores +20 · 28 citations
Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · Medicine · #Antibody #Biology #Biopharmaceutical #Biosimilars and Bioanalytical Methods #Biotechnology #Clinical trial #Drug #Drug development #Immunogenicity #Immunology #Intensive care medicine #Internal medicine #Licensure #Medicine #Monoclonal and Polyclonal Antibodies Research #Pharmacology #Protein purification and stability
- Immunogenicity and safety of two live-attenuated tetravalent dengue vaccine formulations in healthy Australian adults☆
2005/09/24 by Scott Kitchener, S KITCHENER, M NISSEN +11 · 20 citations
Medicine · #Antibody #Dengue fever #Dengue vaccine #Dengue virus #Immunogenicity #Immunology #Medicine #Mosquito-borne diseases and control #Neutralizing antibody #Reactogenicity #Serotype #Vaccination #Viral Infections and Outbreaks Research #Viral Infections and Vectors #Virology
- Recombinant Listeria Vaccines Containing PEST Sequences Are Potent Immune Adjuvants for the Tumor-Associated Antigen Human Papillomavirus-16 E7
2004/12/15 by Duane A. Sewell, Vafa Shahabi, George R. Gunn +3 · 28 citations
Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · #Antigen #Biology #Cancer Research and Treatments #Epitope #Fusion protein #Gene #Genetics #Immune system #Immunogenicity #Immunology #Immunotherapy and Immune Responses #Listeria #Listeria monocytogenes #Listeriolysin O #Microbiology #Recombinant DNA #Virology #Virus-based gene therapy research
- Recommendations for the design and optimization of immunoassays used in the detection of host antibodies against biotechnology products
2004/06/01 by Anthony R Mire-Sluis, Anthony R. Mire‐Sluis, Yu Chen Barrett +17 · 31 citations
Biochemistry, Genetics and Molecular Biology · Engineering · Immunology and Microbiology · Medicine · #Antibody #Antibody response #Biochemical engineering #Biology #Biopharmaceutical #Biosimilars and Bioanalytical Methods #Biotechnology #Biotin and Related Studies #Computational biology #Engineering #Immunoassay #Immunogenicity #Immunology #Licensure #Medicine #Monoclonal and Polyclonal Antibodies Research
- A panel of MHC class I restricted viral peptides for use as a quality control for vaccine trial ELISPOT assays
2002/02/01 by Jeffrey R Currier, Jeffrey R. Currier, Ellen Kuta +12 · 27 citations
Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · #Antigen #Biology #CD8 #CTL* #Cytotoxic T cell #ELISPOT #Epitope #HIV Research and Treatment #Human leukocyte antigen #Immune system #Immunogenicity #Immunology #Immunotherapy and Immune Responses #In vitro #Interferon gamma #MHC class I #Major histocompatibility complex #Peripheral blood mononuclear cell #Virology #vaccines and immunoinformatics approaches
- Development of a novel osteochondral graft for cartilage repair
1998/08/01 by B. C. Toolan, Brian C. Toolan, S. R. Frenkel +4 · 6 citations
Chemistry · Medicine · #Anatomy #Articular cartilage #Articular cartilage repair #Biochemistry #Biology #Biomedical engineering #Biotechnology #Cartilage #Chemistry #Collagenase #Enzyme #Hyaluronidase #Immune system #Immunogenicity #Immunology #In vivo #Knee injuries and reconstruction techniques #Materials science #Medicine #Osteoarthritis #Osteoarthritis Treatment and Mechanisms #Pathology #Periodontal Regeneration and Treatments #Proteoglycan #Surgery #Transplantation
- Long Charge-Rich α-Helices in Systemic Autoantigens
1993/09/01 by J.G. Dohlman, A. Lupas, Andrei N. Lupas +2 · 2 citations
Chemistry · Immunology and Microbiology · Medicine · #Antibody #Autoantibody #Biochemistry #Biology #Biophysics #Celiac Disease Research and Management #Chemistry #Coiled coil #Computational biology #Epitope #Gene #Genetics #Globular protein #Immunogenicity #Monoclonal and Polyclonal Antibodies Research #Peptide sequence #Protein structure #T-cell and B-cell Immunology
- The importance of antibody affinity in the performance of immunoassays for antibody
1985/04/01 by Michael W. Steward, Michael Steward, Andrew M. Lew · 9 citations
Chemistry · Medicine · #Advanced Proteomics Techniques and Applications #Antibody #Biochemistry #Biology #Chemistry #Chromatography #Computational biology #Gene #Genetics #Immunogenicity #Immunoglobulin light chain #Mass Spectrometry Techniques and Applications #Mass spectrometry #Molecular biology #Monoclonal and Polyclonal Antibodies Research #Monoclonal antibody #Peptide sequence #Tandem mass spectrometry
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