1. Drugs Targeting CD20 in Multiple Sclerosis: Pharmacology, Efficacy, Safety, and Tolerability
   2024/03/01 by Alise K. Carlson, Alise Carlson, Moein Amin +1 · 25 citations
   Immunology and Microbiology · Medicine · #Adverse effect #CAR-T cell therapy research #Clinical trial #Fingolimod #Immunology #Immunotherapy and Immune Responses #Intensive care medicine #Internal medicine #Lymphoma #Medicine #Monoclonal and Polyclonal Antibodies Research #Multiple sclerosis #Ocrelizumab #Ofatumumab #Oncology #Pharmacology #Rituximab #Teriflunomide #Tolerability
2. Telepsychiatry versus face-to-face treatment: systematic review and meta-analysis of randomised controlled trials
   2023/09/01 by Katsuhiko Hagi, Shunya Kurokawa, Akihiro Takamiya +6 · 19 citations
   Medicine · Psychology · #Adverse effect #COVID-19 and Mental Health #Digital Mental Health Interventions #Discontinuation #Face-to-face #Health care #Internal medicine #Medicine #Meta-analysis #Psychiatry #Telemedicine #Telemedicine and Telehealth Implementation #Telepsychiatry #Tolerability
3. Dose escalation randomised study of efmarodocokin alfa in healthy volunteers and patients with ulcerative colitis
   2023/02/02 by Frank Wagner, John C Mansfield, John Mansfield +15 · 13 citations
   Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · Medicine · #Adverse effect #Dermatology #Dermatology and Skin Diseases #Dosing #Erythema #Gastroenterology #Inflammatory Bowel Disease #Internal medicine #Medicine #Pathology #Pharmacodynamics #Pharmacokinetics #Pharmacology #Placebo #Psoriasis #Psoriasis: Treatment and Pathogenesis #Surgery #Tolerability #Ulcerative colitis
4. The novel persistent sodium current inhibitor PRAX‐562 has potent anticonvulsant activity with improved protective index relative to standard of care sodium channel blockers
   2022/01/17 by Kristopher M. Kahlig, Liam Scott, Robert J. Hatch +5 · 17 citations
   Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · Neuroscience · Psychology · #Anesthesia #Anticonvulsant #Biochemistry #Carbamazepine #Chemistry #Epilepsy #Inhibitory postsynaptic potential #Internal medicine #Ion channel regulation and function #Lamotrigine #Medicine #Neuroscience #Neuroscience and Neural Engineering #Neuroscience and Neuropharmacology Research #Patch clamp #Pharmacology #Psychology #Receptor #Sodium #Sodium channel #Sodium channel blocker #Tolerability
5. European clinical guidelines for Tourette syndrome and other tic disorders—version 2.0. Part IV: deep brain stimulation
   2021/10/04 by Natalia Szejko, Yulia Worbe, Andreas Hartmann +15 · 1 citation
   Psychology · Neuroscience · Medicine · #Obsessive-Compulsive Spectrum Disorders #Autism Spectrum Disorder Research #Parkinson's Disease Mechanisms and Treatments #Tourette syndrome #Deep brain stimulation #Tolerability #Randomized controlled trial #Tics #Psychology #Medicine #Psychiatry #Clinical trial #Pediatrics #Adverse effect #Internal medicine
6. Evaluating the Impact of Cost on the Treatment Algorithm for Chronic Idiopathic Constipation: Cost-Effectiveness Analysis
   2021/08/13 by Eric D. Shah, Kyle Staller, Judy Nee +6 · 18 citations
   Biochemistry, Genetics and Molecular Biology · Medicine · #Adverse effect #Chronic constipation #Clinical trial #Constipation #Cost effectiveness #Gastroesophageal reflux and treatments #Gastrointestinal motility and disorders #Health care #Inflammatory Bowel Disease #Intensive care medicine #Internal medicine #Lubiprostone #Medicaid #Medical prescription #Medicine #Pharmacology #Physical therapy #Prescription drug #Reimbursement #Tolerability
7. Initial monotherapy with eslicarbazepine acetate for the management of adult patients with focal epilepsy in clinical practice: a meta-analysis of observational studies
   2021/05/17 by Silvia Fernández-Anaya, Vicente Villanueva, José M. Serratosa +5 · 1 citation
   Medicine · Neuroscience · #Adverse effect #Clinical Practice #Confidence interval #EEG and Brain-Computer Interfaces #Epilepsy #Epilepsy research and treatment #Internal medicine #Medicine #Meta-analysis #Neuroscience and Neuropharmacology Research #Observational study #Pediatrics #Physical therapy #Psychiatry #Randomized controlled trial #Retrospective cohort study #Tolerability
8. Nintedanib: A Review in Fibrotic Interstitial Lung Diseases
   2021/03/25 by Yvette N. Lamb · 26 citations
   Medicine · #Adverse effect #Eosinophilic Disorders and Syndromes #Idiopathic pulmonary fibrosis #Internal medicine #Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis #Interstitial lung disease #Lung #Medicine #Nintedanib #Pirfenidone #Systemic Sclerosis and Related Diseases #Tolerability
9. A Phase 3 Open-Label Study of Elexacaftor/Tezacaftor/Ivacaftor in Children 6 through 11 Years of Age with Cystic Fibrosis and at Least One F508del Allele
   2021/03/18 by Edith T. Zemanick, Jennifer L. Taylor‐Cousar, Jane C. Davies +19 · 2 citations
   Health Professions · Medicine · #Adverse effect #Confidence interval #Cystic Fibrosis Research Advances #Cystic fibrosis #Cystic fibrosis transmembrane conductance regulator #Gastroenterology #Internal medicine #Ivacaftor #Medicine #Neonatal Respiratory Health Research #Pediatric health and respiratory diseases #Pediatrics #Tolerability
10. Long-term Outcome of Deep Brain Stimulation of the Ventral Part of the Anterior Limb of the Internal Capsule in a Cohort of 50 Patients With Treatment-Refractory Obsessive-Compulsive Disorder
    2020/08/28 by Ilse Graat, Roel Mocking, Roel J. T. Mocking +8 · 15 citations
    Medicine · Neuroscience · Psychology · #Adverse effect #Anxiety #Cohort #Deep brain stimulation #Disease #Global Assessment of Functioning #Hamilton Anxiety Rating Scale #Internal medicine #Medicine #Neurological disorders and treatments #Obsessive-Compulsive Spectrum Disorders #Psychiatry #Psychology #Quality of life (healthcare) #Rating scale #Schizophrenia (object-oriented programming) #Tolerability #Vagus Nerve Stimulation Research
11. Response to Inhibition of Receptor‐Interacting Protein Kinase 1 (RIPK1) in Active Plaque Psoriasis: A Randomized Placebo‐Controlled Study
    2020/04/17 by Kathleen Weisel, Scott B. Berger, Scott Berger +10 · 25 citations
    Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · Medicine · #Adverse effect #Cytokine Signaling Pathways and Interactions #Gastroenterology #Immunology #Internal medicine #Medicine #NF-κB Signaling Pathways #Pathology #Pharmacodynamics #Pharmacokinetics #Pharmacology #Placebo #Psoriasis #Psoriasis: Treatment and Pathogenesis #Randomized controlled trial #Tolerability
12. Stanford Accelerated Intelligent Neuromodulation Therapy for Treatment-Resistant Depression
    2020/04/07 by Eleanor J. Cole, Eleanor Cole, Katy H. Stimpson +31 · 47 citations
    Medicine · Neuroscience · Psychology · #Adverse effect #Brain stimulation #Cognition #Deep brain stimulation #Depression (economics) #Disease #Dorsolateral prefrontal cortex #Functional Brain Connectivity Studies #Internal medicine #Major depressive disorder #Medicine #Neurological disorders and treatments #Neuromodulation #Neuropsychology #Parkinson's disease #Physical medicine and rehabilitation #Prefrontal cortex #Psychiatry #Psychology #Stimulation #Tolerability #Transcranial Magnetic Stimulation Studies #Transcranial direct-current stimulation #Treatment-resistant depression
13. Efficacy of Deep Brain Stimulation of the Ventral Anterior Limb of the Internal Capsule for Refractory Obsessive-Compulsive Disorder: A Clinical Cohort of 70 Patients
    2020/01/07 by Damiaan Denys, Ilse Graat, Roel Mocking +8 · 30 citations
    Medicine · Psychology · #Adverse effect #Anxiety #Cohort #Deep brain stimulation #Hamilton Anxiety Rating Scale #Internal capsule #Internal medicine #Magnetic resonance imaging #Medicine #Neurological disorders and treatments #Obsessive-Compulsive Spectrum Disorders #Pain Management and Treatment #Parkinson's disease #Psychiatry #Psychology #Radiology #Rating scale #Refractory (planetary science) #Tolerability
14. Dapagliflozin: A Review in Type 2 Diabetes
    2019/06/25 by Sohita Dhillon · 25 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Adverse effect #Dapagliflozin #Diabetes Treatment and Management #Diabetes mellitus #Diabetic ketoacidosis #Endocrinology #Insulin #Intensive care medicine #Internal medicine #Medicine #Metabolism, Diabetes, and Cancer #Metformin #Pancreatic function and diabetes #Population #Tolerability #Type 2 diabetes
15. Efficacy and Safety of Flexibly Dosed Esketamine Nasal Spray Combined With a Newly Initiated Oral Antidepressant in Treatment-Resistant Depression: A Randomized Double-Blind Active-Controlled Study
    2019/05/21 by Vanina Popova, Ella J. Daly, Ella Daly +17 · 39 citations
    Medicine · Psychology · #Adverse effect #Anesthesia #Antidepressant #Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes #Depression (economics) #Internal medicine #Medicine #Nasal administration #Nasal spray #Pharmacology #Placebo #Psychedelics and Drug Studies #Tolerability #Treatment of Major Depression #Treatment-resistant depression
16. The KHENERGY Study: Safety and Efficacy of KH176 in Mitochondrial m.3243A>G Spectrum Disorders
    2018/07/30 by Mirian C.H. Janssen, Mirian C. H. Janssen, Saskia Koene +12 · 25 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #ATP Synthase and ATPases Research #Adverse effect #Clinical trial #Coenzyme Q10 studies and effects #Crossover study #Internal medicine #Medicine #Mitochondrial Function and Pathology #Pathology #Pharmacodynamics #Pharmacokinetics #Pharmacology #Placebo #Randomized controlled trial #Tolerability
17. Prospective, randomized, double‐blind assessment of topical bakuchiol and retinol for facial photoageing
    2018/06/27 by S. Dhaliwal, Simran Dhaliwal, Iryna Rybak +23 · 26 citations
    Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · Medicine · #Adverse effect #Bioactive natural compounds #Dermatology #Internal medicine #Medicine #Pharmacology #Phytoestrogen effects and research #Plant chemical constituents analysis #Retinol #Tolerability #Vitamin
18. Tofacitinib: A Review in Rheumatoid Arthritis
    2017/11/14 by Sohita Dhillon · 27 citations
    Medicine · #Adverse effect #Autoimmune and Inflammatory Disorders Research #Internal medicine #Janus kinase inhibitor #Medicine #Methotrexate #Pharmacology #Rheumatoid Arthritis Research and Therapies #Rheumatoid arthritis #Systemic Lupus Erythematosus Research #Tofacitinib #Tolerability
19. Management of Allergic Rhinitis: A Review for the Community Pharmacist
    2017/10/25 by J. Russell May, William K. Dolen · 1 citation
    Medicine · #Adverse effect #Allergic Rhinitis and Sensitization #Anesthesia #Antihistamine #Asthma and respiratory diseases #Cetirizine #Corticosteroid #Desloratadine #Fluticasone propionate #Internal medicine #Loratadine #Medicine #Nasal administration #Nasal decongestant #Pharmacology #Sinusitis and nasal conditions #Tolerability
20. Dovitinib in patients with gastrointestinal stromal tumour refractory and/or intolerant to imatinib
    2017/08/29 by Heikki Joensuu, Jean-Yves Blay, Jean‐Yves Blay +22 · 17 citations
    Medicine · #Adverse effect #Chemotherapy #Clinical endpoint #Clinical trial #Dysgeusia #Gastroenterology #Gastrointestinal Bleeding Diagnosis and Treatment #Gastrointestinal Tumor Research and Treatment #Gastrointestinal disorders and treatments #GiST #Imatinib #Imatinib mesylate #Internal medicine #Medicine #Progressive disease #Refractory (planetary science) #Response Evaluation Criteria in Solid Tumors #Stromal cell #Surgery #Tolerability
21. GERI-BD: A Randomized Double-Blind Controlled Trial of Lithium and Divalproex in the Treatment of Mania in Older Patients With Bipolar Disorder
    2017/08/04 by Robert C. Young, Benoit H. Mulsant, Martha Sajatovic +73 · 22 citations
    Medicine · Psychology · #Adverse effect #Anesthesia #Bipolar Disorder and Treatment #Bipolar I disorder #Bipolar disorder #Divalproex #Electroconvulsive Therapy Studies #Internal medicine #Lithium (medication) #Mania #Medicine #Mood #Mood stabilizer #Psychiatry #Psychology #Randomized controlled trial #Schizophrenia research and treatment #Sedation #Tolerability #Young Mania Rating Scale
22. Reduced-dose radiotherapy for human papillomavirus-associated squamous-cell carcinoma of the oropharynx: a single-arm, phase 2 study
    2017/04/20 by Allen M Chen, Allen M. Chen, Carol Felix +23 · 2 citations
    Medicine · #Adverse effect #Carboplatin #Carcinoma #Chemoradiotherapy #Chemotherapy #Cisplatin #Clinical endpoint #Clinical trial #Esophageal Cancer Research and Treatment #Head and Neck Cancer Studies #Induction chemotherapy #Internal medicine #Medicine #Oncology #Oral health in cancer treatment #Phases of clinical research #Radiation therapy #Response Evaluation Criteria in Solid Tumors #Stage (stratigraphy) #Surgery #Tolerability
23. Inhibiting Plasma Kallikrein for Hereditary Angioedema Prophylaxis
    2017/02/17 by Aleena Banerji, Paula J. Busse, Mustafa M. Shennak +25 · 2 citations
    Medicine · Immunology and Microbiology · #Coagulation, Bradykinin, Polyphosphates, and Angioedema #Complement system in diseases #Hemophilia Treatment and Research #Hereditary angioedema #Angioedema #Medicine #C1-inhibitor #Kallikrein #Placebo #Adverse effect #Bradykinin #Gastroenterology #High-molecular-weight kininogen #Internal medicine #Tolerability #Kininogen #Pharmacology #Anesthesia #Immunology #Pathology
24. Curcumin, the golden nutraceutical: multitargeting for multiple chronic diseases
    2016/09/17 by Ajaikumar B Kunnumakkara, Ajaikumar B. Kunnumakkara, Devivasha Bordoloi +6 · 29 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · Pharmacology, Toxicology and Pharmaceutics · #Adverse effect #Bioinformatics #Biology #Clinical trial #Curcuma #Curcumin #Curcumin's Biomedical Applications #Ginger and Zingiberaceae research #Internal medicine #Medicine #Nutraceutical #Pathology #Pharmacology #Piperaceae Chemical and Biological Studies #Resveratrol #Tolerability #Traditional medicine
25. Effect of 5α-Reductase Inhibitors on Sexual Function: A Meta-Analysis and Systematic Review of Randomized Controlled Trials
    2016/07/29 by Luhao Liu, Shankun Zhao, Futian Li +6 · 1 citation
    Medicine · #Urinary Bladder and Prostate Research #Sexual function and dysfunction studies #Hair Growth and Disorders #Dutasteride #Medicine #Sexual function #Erectile dysfunction #Finasteride #Sexual dysfunction #Randomized controlled trial #Meta-analysis #Tolerability #Libido #Internal medicine #Adverse effect #Prostate
26. Pharmacokinetics, Safety and Tolerability of ABT-494, a Novel Selective JAK 1 Inhibitor, in Healthy Volunteers and Subjects with Rheumatoid Arthritis
    2016/06/06 by Mohamed-Eslam F. Mohamed, Mohamed‐Eslam F. Mohamed, Heidi S. Camp +4 · 2 citations
    Immunology and Microbiology · Medicine · #Adverse effect #Cytokine Signaling Pathways and Interactions #Internal medicine #Medicine #Pharmacokinetics #Pharmacology #Psoriasis: Treatment and Pathogenesis #Rheumatoid Arthritis Research and Therapies #Rheumatoid arthritis #Tolerability
27. Effect of age and sex on efficacy and tolerability of β blockers in patients with heart failure with reduced ejection fraction: individual patient data meta-analysis
    2016/04/20 by Dipak Kotecha, Luís Manzano, Henry Krum +18 · 1 citation
    Medicine · #Heart Failure Treatment and Management #Cardiac pacing and defibrillation studies #Acute Myocardial Infarction Research #Medicine #Hazard ratio #Ejection fraction #Heart failure #Tolerability #Placebo #Internal medicine #Proportional hazards model #Confidence interval #Sinus rhythm #Cardiology #Adverse effect #Atrial fibrillation
28. The Application and Outcome of Standard of Care Treatment in Elderly Women with Ovarian Cancer: A Literature Review over the Last 10 Years
    2016/03/23 by S. J. Gibson, Gini F. Fleming, Sarah M. Temkin +1 · 1 citation
    Medicine · Biochemistry, Genetics and Molecular Biology · #Ovarian cancer diagnosis and treatment #BRCA gene mutations in cancer #Intraperitoneal and Appendiceal Malignancies #Medicine #Ovarian cancer #Tolerability #Disease #Standard of care #Cancer #Oncology #Geriatric oncology #Population #Intensive care medicine #Internal medicine #Gerontology #Gynecology #Alternative medicine #Pathology
29. Synthesis of substituted phenylcarbamates of N-cyclobutylformylated chitosan and their application as chiral selectors in enantioseparation
    2016/01/01 by Juan Zhang, Xiao-Chen Wang, Wei Chen +2 · 3 citations
    Chemistry · Engineering · #Analytical Chemistry and Chromatography #Catalysis #Chemistry #Chiral stationary phase #Chitosan #Chromatography #Combinatorial chemistry #Enantiomer #Enantioselective synthesis #Mass Spectrometry Techniques and Applications #Microfluidic and Capillary Electrophoresis Applications #Organic chemistry #Pharmacology #Tolerability
30. Ant venom immunotherapy in Australia: the unmet need
    2014/07/01 by Raymond J Mullins, Simon G.A. Brown · 2 citations
    Medicine · #Food Allergy and Anaphylaxis Research #Allergic Rhinitis and Sensitization #Contact Dermatitis and Allergies #Venom #Anaphylaxis #Tolerability #Allergy #Medicine #Immunotherapy #Immunology #Bee venom #Biology #Pharmacology #Ecology #Adverse effect #Zoology #Immune system

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