- Vaccination with mRNA-encoded nanoparticles drives early maturation of HIV bnAb precursors in humans
2025/05/15 by Jordan R. Willis, Madhu Prabhakaran, Michelle K. Muthui +97 · 28 citations
Immunology and Microbiology · Medicine · #Antibody #B cell #Biology #Gene #Genetics #HIV Research and Treatment #HIV vaccine #HIV/AIDS Research and Interventions #Heterologous #Immunogen #Immunogenicity #Immunology #Immunotherapy and Immune Responses #Monoclonal antibody #Priming (agriculture) #Somatic hypermutation #Vaccination #Vaccine trial #Virology
- Diversification of the VH3‐53 immunoglobulin gene segment by somatic hypermutation results in neutralization of SARS‐CoV‐2 virus variants
2024/04/09 by Matthias Bruhn, Maureen Obara, Abdus Salam +10 · 10 citations
Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · Medicine · #Antibody #Antigen-presenting cell #B cell #BCL6 #Biology #Gene #Genetics #Germinal center #Immune system #Immunoglobulin class switching #Immunology #Memory B cell #Naive B cell #SARS-CoV-2 and COVID-19 Research #Single-cell and spatial transcriptomics #Somatic hypermutation #T cell #T-cell and B-cell Immunology #Virology #Virus
- How I Diagnose Rosai-Dorfman Disease
2023/05/11 by Aishwarya Ravindran, Karen L. Rech, Karen L Rech · 24 citations
Medicine · #B cell #CD68 #Cardiac tumors and thrombi #Disease #Emperipolesis #Erdheim–Chester disease #Histiocyte #Histiocytic Disorders and Treatments #Histiocytosis #Immunohistochemistry #Immunology #Medicine #PAX5 #Pathology #Rosai–Dorfman disease #Tuberous Sclerosis Complex Research
- Expansion of plasmablasts and loss of memory B cells in peripheral blood from COVID‐19 patients with pneumonia
2020/07/24 by Sara De Biasi, Domenico Lo Tartaro, Marianna Meschiari +18 · 28 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Antibody #Antigen #Antigen-presenting cell #B cell #Biology #COVID-19 Clinical Research Studies #Diabetes and associated disorders #Flow cytometry #Humoral immunity #Immune system #Immunoglobulin G #Immunoglobulin M #Immunology #Internal medicine #Medicine #Memory B cell #Naive B cell #Pneumonia #SARS-CoV-2 and COVID-19 Research #T cell
- Epstein–Barr Virus in Multiple Sclerosis: Theory and Emerging Immunotherapies
2019/12/17 by Amit Bar‐Or, Michael P. Pender, Rajiv Khanna +7 · 1 citation
Medicine · #Antibody #B cell #Biology #Disease #Epstein–Barr virus #Herpesvirus Infections and Treatments #Immune system #Immunology #Medicine #Multiple Sclerosis Research Studies #Multiple sclerosis #Pathology #Polyomavirus and related diseases #Virology #Virus
- MALT lymphoma: epidemiology, clinical diagnosis and treatment
2018/09/01 by Petruța Violeta Filip, Denisa Cuciureanu, Laura Sorina Diaconu +3 · 1 citation
Medicine · Immunology and Microbiology · #Helicobacter pylori-related gastroenterology studies #Lymphoma Diagnosis and Treatment #Galectins and Cancer Biology #Helicobacter pylori #Lymphoma #Marginal zone #MALT lymphoma #Medicine #Mucosa-associated lymphoid tissue #Lymphatic system #Pathology #Gastrointestinal tract #Epidemiology #Gastric mucosa #Gastric lymphoma #Pathogenesis #Stomach #B cell #Gastroenterology #Immunology #Internal medicine #Antibody
- The enigmatic function of IgD: some answers at last
2018/05/07 by Cindy Gutzeit, Kang Chen, Andrea Cerutti · 29 citations
Immunology and Microbiology · #Antibody #Antigen #Antigen-presenting cell #B cell #B-1 cell #Biology #Cell biology #Effector #Immune Cell Function and Interaction #Immune system #Immunoglobulin D #Immunology #Immunotherapy and Immune Responses #T cell #T-cell and B-cell Immunology
- Transformation of marginal zone lymphoma (and association with other lymphomas)
2016/11/04 by Carla Casulo, Jonathan W. Friedberg, Jonathan Friedberg · 1 citation
Medicine · #B cell #CNS Lymphoma Diagnosis and Treatment #Disease #Follicular lymphoma #Immunology #Lymphoma #Lymphoma Diagnosis and Treatment #Lymphoplasmacytic Lymphoma #MALT lymphoma #Marginal zone #Medicine #Pathology #Spleen #Splenectomy #Splenic marginal zone lymphoma #Viral-associated cancers and disorders #Waldenstrom macroglobulinemia
- Somatic hypermutation in immunity and cancer: Critical analysis of strand-biased and codon-context mutation signatures
2016/07/10 by Edward J. Steele · 1 citation
Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · #Antibody #B cell #Biology #CRISPR and Genetic Engineering #Cytidine deaminase #DNA #DNA polymerase #Gene #Genetics #Immune Cell Function and Interaction #Molecular biology #RNA #Reverse transcriptase #Somatic hypermutation #T-cell and B-cell Immunology
- B-cell–specific conditional expression of Myd88p.L252P leads to the development of diffuse large B-cell lymphoma in mice
2016/04/06 by Gero Knittel, Paul Liedgens, Darya Korovkina +38 · 25 citations
Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · Medicine · #Antibody #B cell #Biology #Cancer research #Diffuse large B-cell lymphoma #Gene #Genetics #Germinal center #Immune Cell Function and Interaction #Immunology #Lymphoma #Lymphoma Diagnosis and Treatment #Mutation #NF-κB Signaling Pathways
- Effects of B Cell Depletion on Early Mycobacterium tuberculosis Infection in Cynomolgus Macaques
2016/02/17 by Jiayao Phuah, Jia Yao Phuah, Eileen A. Wong +9 · 28 citations
Medicine · #Antibody #B cell #Biology #Cytokine #Cytokine Signaling Pathways and Interactions #Humoral immunity #Immune system #Immunity #Immunology #Macaque #Medicine #Mycobacterium research and diagnosis #Mycobacterium tuberculosis #Pathology #Tuberculosis #Tuberculosis Research and Epidemiology
- Icetexane Diterpenoids from Perovskia atriplicifolia
2015/01/22 by Zhi‐Yong Jiang, Yi-Jiang Yu, Chao‐Guan Huang +6 · 1 citation
Biochemistry, Genetics and Molecular Biology · Medicine · Chemistry · #Ginseng Biological Effects and Applications #Traditional Chinese Medicine Analysis #Natural product bioactivities and synthesis #Hepatitis B virus #Stereochemistry #Hepatitis B #Duck hepatitis B virus #Group B #In vitro #Chemistry #B cell #Hepadnaviridae #Virology #Virus #Biology #Biochemistry #Medicine #Immunology #Antibody
- Interleukin-10+ Regulatory B Cells Arise Within Antigen-Experienced CD40+ B Cells to Maintain Tolerance to Islet Autoantigens
2014/09/03 by Sonja Kleffel, Andrea Vergani, Sara Tezza +17 · 25 citations
Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · Medicine · #Antibody #Antigen #B cell #Biology #CD40 #Cytotoxic T cell #Diabetes and associated disorders #Diabetes mellitus #Endocrinology #Genetics #Immune tolerance #Immunology #Islet #Pancreatic function and diabetes #Regulatory B cells #T-cell and B-cell Immunology
- Belimumab for Systemic Lupus Erythematosus
2013/04/17 by Bevra H. Hahn · 1 citation
Medicine · Immunology and Microbiology · #Systemic Lupus Erythematosus Research #T-cell and B-cell Immunology #Monoclonal and Polyclonal Antibodies Research #Belimumab #Medicine #Monoclonal antibody #Adverse effect #Monoclonal #Immunology #Lupus erythematosus #Systemic lupus erythematosus #B-cell activating factor #Disease #Antibody #B cell #Internal medicine
- Activated B Cells in the Granulomas of Nonhuman Primates Infected with Mycobacterium tuberculosis
2012/06/19 by Jia Yao Phuah, Joshua T. Mattila, Philana Ling Lin +2 · 30 citations
Immunology and Microbiology · Medicine · #Antibody #Antigen #B cell #Biology #CXCR5 #Germinal center #Granuloma #Humoral immunity #Immune system #Immunity #Immunology #Lymph node #Medicine #Mycobacterium research and diagnosis #Mycobacterium tuberculosis #Pathology #T-cell and B-cell Immunology #Tuberculosis #Tuberculosis Research and Epidemiology
- A phase III, randomized, placebo-controlled study of belimumab, a monoclonal antibody that inhibits B lymphocyte stimulator, in patients with systemic lupus erythematosus
2011/09/01 by Richard Furie, Michelle Petri, Omid Zamani +18 · 37 citations
Medicine · #Antibody #B cell #B-cell activating factor #Belimumab #Clinical endpoint #Disease #Gastroenterology #Immunology #Internal medicine #Liver Diseases and Immunity #Lupus erythematosus #Medicine #Multiple Sclerosis Research Studies #Pathology #Placebo #Post-hoc analysis #Randomized controlled trial #Systemic Lupus Erythematosus Research #Systemic lupus erythematosus
- Efficacy and safety of belimumab in patients with active systemic lupus erythematosus: a randomised, placebo-controlled, phase 3 trial
2011/02/01 by Sandra Navarra, Sandra V Navarra, Renato M Guzmán +27 · 2 citations
Medicine · Neuroscience · #Adverse effect #Alternative medicine #Antibody #Autoimmune disease #B cell #B-cell activating factor #Belimumab #Clinical endpoint #Clinical trial #Connective tissue disease #Disease #Immunology #Internal medicine #Lupus erythematosus #Medicine #Multiple Sclerosis Research Studies #Pathology #Placebo #Randomized controlled trial #Systemic Lupus Erythematosus Research #Systemic lupus erythematosus #Vagus Nerve Stimulation Research
- Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19
2010/07/29 by James N. Kochenderfer, Wyndham H. Wilson, John E. Janik +12 · 39 citations
Biochemistry, Genetics and Molecular Biology · Engineering · Medicine · #Adoptive cell transfer #Antibody #Antigen #B cell #Biology #Bone marrow #CAR-T cell therapy research #CD19 #Cancer research #Chimeric antigen receptor #Immune system #Immunology #Lymphoma #Medicine #Nanowire Synthesis and Applications #T cell #Viral Infectious Diseases and Gene Expression in Insects
- Treatment of gastric marginal zone lymphoma of MALT type
2010/06/30 by Anastasios Stathis, Francesco Bertoni, Emanuele Zucca · 1 citation
Medicine · #Lymphoma Diagnosis and Treatment #Lymphadenopathy Diagnosis and Analysis #Esophageal Cancer Research and Treatment #Medicine #Helicobacter pylori #MALT lymphoma #Mucosa-associated lymphoid tissue #Lymphoma #Gastroenterology #Marginal zone #Internal medicine #Gastric lymphoma #Gastritis #Disease #Chronic gastritis #Antibiotics #Oncology #Immunology #B cell
- Expansion of circulating T cells resembling follicular helper T cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosus
2009/12/28 by Nicholas Simpson, Paul A. Gatenby, Anastasia Wilson +12 · 27 citations
Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · Medicine · #Antibody #Autoantibody #Autoimmune disease #B cell #Biology #Biomarker #CXCR5 #Diabetes and associated disorders #Disease #Gene #Germinal center #Immunology #Internal medicine #Lupus erythematosus #Lupus nephritis #Medicine #Phenotype #Systemic Lupus Erythematosus Research #Systemic lupus erythematosus #T-cell and B-cell Immunology
- High Expression of the Inhibitory Receptor BTLA in T-Follicular Helper Cells and in B-Cell Small Lymphocytic Lymphoma/Chronic Lymphocytic Leukemia
2009/09/17 by Hasni M’Hidi, Marie‐Laure Thibult, Marie-Laure Thibult +7 · 25 citations
Immunology and Microbiology · Medicine · #Antibody #Antigen #Antigen-presenting cell #B cell #BTLA #Biology #Cancer research #Chronic Lymphocytic Leukemia Research #Chronic lymphocytic leukemia #Follicular dendritic cells #Follicular lymphoma #Germinal center #Immune Cell Function and Interaction #Immune system #Immunology #Leukemia #Lymphoma #Lymphoma Diagnosis and Treatment #Mantle zone #Marginal zone #T cell #T lymphocyte
- Helper T Cell-Regulated B Cell Immunity
2006/10/04 by L. J. McHeyzer-Williams, Louise J. McHeyzer‐Williams, Laurent Malherbe +3 · 1 citation
Immunology and Microbiology · #Acquired immune system #Antibody #Antigen #Antigen-presenting cell #B cell #B-1 cell #Biology #Cell biology #Effector #Germinal center #Immune Cell Function and Interaction #Immune system #Immunity #Immunology #Immunotherapy and Immune Responses #Memory B cell #Priming (agriculture) #T cell #T-cell and B-cell Immunology
- BAFF, APRIL and their receptors: Structure, function and signaling
2006/08/18 by Claudia Bossen, Pascal Schneider · 1 citation
Biochemistry, Genetics and Molecular Biology · Chemistry · Immunology and Microbiology · #Antibody #B cell #B-cell activating factor #Biochemistry #Biology #Cell biology #Chemistry #Gene #Gene isoform #Immune Cell Function and Interaction #Immune system #Immunology #NF-κB Signaling Pathways #Receptor #Signal transduction #T-cell and B-cell Immunology
- A Soluble BAFF Antagonist, BR3-Fc, Decreases Peripheral Blood B Cells and Lymphoid Tissue Marginal Zone and Follicular B Cells in Cynomolgus Monkeys
2006/02/01 by Yulia Vugmeyster, Dhaya Seshasayee, Wesley Chang +18 · 1 citation
Immunology and Microbiology · Medicine · #Antibody #B cell #B-cell activating factor #Biology #Germinal center #Immunology #Immunotherapy and Immune Responses #Lymphatic system #Marginal zone #Medicine #Monoclonal and Polyclonal Antibodies Research #Pathology #Receptor #Spleen #T-cell and B-cell Immunology
- The role of APRIL and BAFF in lymphocyte activation
2005/04/15 by Pascal Schneider · 1 citation
Immunology and Microbiology · #Antibody #B cell #B-cell activating factor #Biology #CD154 #CD40 #Cell biology #Cytotoxic T cell #Genetics #Germinal center #Immune Cell Function and Interaction #Immunoglobulin class switching #Immunology #Immunotherapy and Immune Responses #T-cell and B-cell Immunology
- Homeostatic niche specification among naïve and activated B cells: A growing role for the BLyS family of receptors and ligands
2005/03/17 by Jenni E. Crowley, Laura S. Treml, Jason Stadanlick +4 · 1 citation
Immunology and Microbiology · #Antibody #B cell #B-cell activating factor #Biology #Cell biology #Ecology #Genetics #Homeostasis #Immune Cell Function and Interaction #Immune Response and Inflammation #Immunology #Niche #Receptor #T-cell and B-cell Immunology
- VavP-Bcl2 transgenic mice develop follicular lymphoma preceded by germinal center hyperplasia
2003/11/25 by Alexander Egle, Alan W. Harris, Mary L. Bath +3 · 26 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Antibody #B cell #Biology #Center (category theory) #Chemistry #Chronic Lymphocytic Leukemia Research #Follicular lymphoma #Gene #Genetically modified mouse #Genetics #Germinal center #Immunology #Lymphoma #Lymphoma Diagnosis and Treatment #Medicine #PI3K/AKT/mTOR signaling in cancer #Pathology #Transgene
- Generation and characterization of LymphoStat‐B, a human monoclonal antibody that antagonizes the bioactivities of B lymphocyte stimulator
2003/11/01 by Kevin P. Baker, Bryan Edwards, Sarah Main +18 · 2 citations
Immunology and Microbiology · Medicine · #T-cell and B-cell Immunology #Immune Response and Inflammation #Monoclonal and Polyclonal Antibodies Research #B-cell activating factor #B cell #Antibody #Immunology #Monoclonal antibody #Cytokine #In vivo #Spleen #Monoclonal #Medicine #Molecular biology #Biology
- The Remarkable Flexibility of the Human Antibody Repertoire; Isolation of Over One Thousand Different Antibodies to a Single Protein, BLyS
2003/10/28 by Bryan Edwards, Bryan M. Edwards, Steven C. Barash +15 · 1 citation
Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · Medicine · #Antibody #Antibody Repertoire #Antigen #B cell #B-cell activating factor #Biochemistry #Biology #Epitope #Glycosylation and Glycoproteins Research #Immune system #Immunoglobulin light chain #Immunology #Molecular biology #Monoclonal and Polyclonal Antibodies Research #Peptide sequence #Phage display #Repertoire #T-cell and B-cell Immunology #Virology
- Impaired uptake of apoptotic cells into tingible body macrophages in germinal centers of patients with systemic lupus erythematosus
2002/01/01 by Irith Baumann, Wasilis Kolowos, Reinhard Voll +9 · 30 citations
Immunology and Microbiology · Medicine · #Antibody #Antigen-presenting cell #Apoptosis #B cell #Biology #CD68 #Follicular dendritic cells #Follicular hyperplasia #Germinal center #Immune system #Immunohistochemistry #Immunology #Lymph #Lymph node #Medicine #Pathology #Phagocytosis and Immune Regulation #Systemic Lupus Erythematosus Research #T cell #TUNEL assay #interferon and immune responses
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