2018/09/01 by Petruța Violeta Filip, Denisa Cuciureanu, Laura Sorina Diaconu +3 · 2 citations
Immunology and Microbiology · Medicine · #Antibody #B cell #Epidemiology #Galectins and Cancer Biology #Gastric lymphoma #Gastric mucosa #Gastroenterology #Gastrointestinal tract #Helicobacter pylori #Helicobacter pylori-related gastroenterology studies #Immunology #Internal medicine #Lymphatic system #Lymphoma #Lymphoma Diagnosis and Treatment #MALT lymphoma #Marginal zone #Medicine #Mucosa-associated lymphoid tissue #Pathogenesis #Pathology #Stomach
paper · pdf · doi:10.25122/jml-2018-0035
openalex publication_date 2018/09/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/04
Primary gastric lymphoma (PGL) represents a rare pathology, which can be easily misdiagnosed because of unspecific symptoms of the digestive tract. Histologically, PGL can vary from indolent marginal zone B-cell lymphoma of the mucosa-associated lymphoid tissue (MALT) to aggressive diffuse large B-cell lymphoma (DLBCL). During the years, clinical trials revealed the important role of Helicobacter pylori (H. pylori) in the pathogenesis of gastric MALT lymphoma. Infection with Helicobacter pylori is an influential promoter of gastric lymphomagenesis initiation. Long-term studies revealed that eradication therapy could regress gastric lymphomas.