1. Acute myeloid leukemia management and research in 2025
   2024/12/10 by Hagop M. Kantarjian, Courtney D. DiNardo, Tapan M. Kadia +8 · 27 citations
   Biochemistry, Genetics and Molecular Biology · Medicine · #Acute Myeloid Leukemia Research #Acute promyelocytic leukemia #Azacitidine #CD33 #Calicheamicin #Cytarabine #Decitabine #Gemtuzumab ozogamicin #Histone Deacetylase Inhibitors Research #Internal medicine #Leukemia #Medicine #Midostaurin #Multiple Myeloma Research and Treatments #Myeloid leukemia #Oncology #Pharmacology #Stem cell #Venetoclax
2. Daratumumab in pediatric relapsed/refractory acute lymphoblastic leukemia or lymphoblastic lymphoma: the DELPHINUS study
   2024/08/19 by Teena Bhatla, Laura E. Hogan, Laura Hogan +32 · 17 citations
   Medicine · #Acute Lymphoblastic Leukemia research #Acute lymphocytic leukemia #Childhood Cancer Survivors' Quality of Life #Chronic Myeloid Leukemia Treatments #Daratumumab #Gastroenterology #Hematopoietic stem cell transplantation #Immune system #Immunology #Internal medicine #Lenalidomide #Leukemia #Lymphoblastic Leukemia #Lymphoblastic lymphoma #Lymphoma #Medicine #Minimal residual disease #Multiple myeloma #Oncology #T cell #Transplantation
3. Approval of brexucabtagene autoleucel for adults with relapsed and refractory acute lymphocytic leukemia
   2022/05/04 by Noelle V. Frey · 21 citations
   Medicine · #Acute lymphocytic leukemia #Biology #CAR-T cell therapy research #Cancer #Chimeric antigen receptor #Food and drug administration #Immunology #Immunotherapy #Internal medicine #Leukemia #Lymphoblastic Leukemia #Medicine #Oncology #Pharmacology #Population #Refractory (planetary science)
4. IL-6 promotes chemoresistance via upregulating CD36 mediated fatty acids uptake in acute myeloid leukemia
   2022/03/25 by Yanjie Zhang, He‐Zhou Guo, Hezhou Guo +4 · 26 citations
   Biochemistry, Genetics and Molecular Biology · Medicine · #Acute Myeloid Leukemia Research #Biochemistry #Biology #Bone and Joint Diseases #CD36 #Cancer research #Cancer, Lipids, and Metabolism #Chromatin immunoprecipitation #Cytokine #Endocrinology #Gene #Gene expression #Immunology #Leukemia #Lipid metabolism #Molecular biology #Myeloid #Myeloid leukemia #Promoter #Receptor
5. Diagnosis and treatment of therapy-related acute myeloid leukemia
   2022/01/31 by Stephen A. Strickland, Norbert Vey · 1 citation
   Medicine · #Acute Myeloid Leukemia Research #Acute Lymphoblastic Leukemia research #Hematopoietic Stem Cell Transplantation #Medicine #Cytarabine #Myeloid leukemia #Oncology #Internal medicine #Daunorubicin #Leukemia #Hematopoietic stem cell transplantation #Myeloid #Transplantation
6. KTE-X19 anti-CD19 CAR T-cell therapy in adult relapsed/refractory acute lymphoblastic leukemia: ZUMA-3 phase 1 results
   2021/04/07 by Bijal D. Shah, Bijal Shah, Michael R. Bishop +26 · 27 citations
   Engineering · Medicine · #Advancements in Semiconductor Devices and Circuit Design #Adverse effect #Biology #CAR-T cell therapy research #Cancer #Chemotherapy #Chimeric antigen receptor #Cyclophosphamide #Cytokine release syndrome #Fludarabine #Gastroenterology #Immunology #Immunotherapy #Integrated Circuits and Semiconductor Failure Analysis #Internal medicine #Leukemia #Medicine #Minimal residual disease #Refractory (planetary science) #Surgery
7. Potent efficacy of MCL-1 inhibitor-based therapies in preclinical models of mantle cell lymphoma
   2019/11/26 by Michael A. Dengler, Charis E. Teh, Rachel Thijssen +8 · 1 citation
   Medicine · #Apoptosis #Bcl-xL #Biology #Bruton's tyrosine kinase #CAR-T cell therapy research #Cancer research #Cell biology #Chronic Lymphocytic Leukemia Research #Chronic lymphocytic leukemia #Genetics #Ibrutinib #Immunology #Leukemia #Lymphoma #Lymphoma Diagnosis and Treatment #Mantle cell lymphoma #Pharmacology #Programmed cell death #Signal transduction #Tyrosine kinase #Venetoclax
8. Hitting back at lymphoma: How do modern diagnostics identify high‐risk diffuse large B‐cell lymphoma subsets and alter treatment?
   2019/07/09 by Jeremy S. Abramson · 1 citation
   Medicine · Immunology and Microbiology · #Lymphoma Diagnosis and Treatment #CAR-T cell therapy research #Immune Cell Function and Interaction #Medicine #Rituximab #Vincristine #Diffuse large B-cell lymphoma #Lymphoma #Ibrutinib #Oncology #Population #Internal medicine #CHOP #Cancer research #Cyclophosphamide #Immunology #Chronic lymphocytic leukemia #Chemotherapy #Leukemia
9. Epidemiology of acute myeloid leukemia: Recent progress and enduring challenges
   2019/04/29 by Rory M. Shallis, Rong Wang, Amy J. Davidoff +3 · 1 citation
   Medicine · #Acute Myeloid Leukemia Research #Disease #Epidemiology #Etiology #Hematological disorders and diagnostics #Hematopoietic Stem Cell Transplantation #Incidence (geometry) #Internal medicine #Leukemia #Medicine #Myeloid #Myeloid leukemia #Oncology #Pediatrics #Transplantation
10. Acute myeloid leukemia: 2019 update on risk‐stratification and management
    2018/10/01 by Elihu H. Estey · 1 citation
    Medicine · #Acute Myeloid Leukemia Research #Myeloproliferative Neoplasms: Diagnosis and Treatment #Hematopoietic Stem Cell Transplantation #Medicine #Myeloid leukemia #Internal medicine #Disease #Incidence (geometry) #Minimal residual disease #Complete remission #Risk stratification #Intensive care medicine #Myeloid #Oncology #Leukemia #Chemotherapy
11. Coexistence of chronic myeloid leukemia and diffuse large B-cell lymphoma with antecedent chronic lymphocytic leukemia: a case report and review of the literature
    2018/03/01 by Khadega A. Abuelgasim, Hinna Rehan, Maha F. Al‐Subaie +4 · 1 citation
    Medicine · #Chronic Lymphocytic Leukemia Research #Chronic Myeloid Leukemia Treatments #Acute Myeloid Leukemia Research #Medicine #Chronic lymphocytic leukemia #Myeloid leukemia #Leukemia #Imatinib mesylate #Imatinib #Pathology #Immunology #Cancer research
12. The interplay of leukemia cells and the bone marrow microenvironment
    2018/02/27 by Delfim Duarte, Edwin D. Hawkins, Cristina Lo Celso · 28 citations
    Medicine · #Acute Myeloid Leukemia Research #Biology #Bone marrow #Cancer research #Hematological disorders and diagnostics #Hematopoietic Stem Cell Transplantation #Immunology #Leukemia #Medicine #Pathology #Stroma #Stromal cell #Tumor cells #Tumor microenvironment
13. Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel
    2016/11/28 by Hartmut Döhner, Elihu H. Estey, David Grimwade +19 · 2 citations
    Medicine · Biochemistry, Genetics and Molecular Biology · #Acute Myeloid Leukemia Research #Histone Deacetylase Inhibitors Research #Chronic Myeloid Leukemia Treatments #Medicine #Expert opinion #Minimal residual disease #Genetic testing #Disease #Myeloid leukemia #Intensive care medicine #Oncology #Family medicine #Leukemia #Internal medicine
14. Resistance to anti-CD19/CD3 BiTE in acute lymphoblastic leukemia may be mediated by disrupted CD19 membrane trafficking
    2016/10/26 by Friederike Braig, Anna Brandt, Mariele Goebeler +9 · 28 citations
    Medicine · #Acute Lymphoblastic Leukemia research #Acute lymphocytic leukemia #Antigen #Blinatumomab #CAR-T cell therapy research #CD19 #Cancer research #Immunology #Leukemia #Lymphoblastic Leukemia #Medicine #Neuroblastoma Research and Treatments
15. Protective mitochondrial transfer from bone marrow stromal cells to acute myeloid leukemic cells during chemotherapy
    2016/06/02 by Ruxanda Moschoi, Véronique Imbert, Marielle Nebout +19 · 30 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Acute Myeloid Leukemia Research #Biochemistry #Biology #Bone marrow #Cancer research #Cancer, Hypoxia, and Metabolism #Cell biology #Chemistry #Glioma Diagnosis and Treatment #Immunology #In vitro #In vivo #Leukemia #Mesenchymal stem cell #Mitochondrion #Myeloid #Myeloid leukemia #Stromal cell
16. Acute Myeloid Leukemia
    2015/09/16 by Hartmut Döhner, Daniel J. Weisdorf, Clara D. Bloomfield · 2 citations
    Medicine · #Acute Myeloid Leukemia Research #Myeloproliferative Neoplasms: Diagnosis and Treatment #Hematopoietic Stem Cell Transplantation #Medicine #Myeloid leukemia #Nosology #Leukemia #Myeloid #Disease #Intensive care medicine #Immunology #Internal medicine #Pathology
17. Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts
    2015/06/23 by Jérôme Paggetti, Jerome Paggetti, Franziska Haderk +11 · 28 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · Immunology and Microbiology · Medicine · #Biology #Cancer #Cancer cell #Cancer research #Cell biology #Chemistry #Chronic Lymphocytic Leukemia Research #Chronic lymphocytic leukemia #Endocrinology #Extracellular vesicles in disease #Galectins and Cancer Biology #Genetics #Immunology #Leukemia #Microvesicles #Phenotype #Secretion #Stromal cell #microRNA
18. Background Ionizing Radiation and the Risk of Childhood Cancer: A Census-Based Nationwide Cohort Study
    2015/02/23 by Ben D. Spycher, Judith E. Lupatsch, Marcel Zwahlen +8 · 1 citation
    Medicine · Health Professions · Environmental Science · #Radiation Dose and Imaging #Radioactivity and Radon Measurements #Radioactive contamination and transfer #Medicine #Cancer #Cancer registry #Cumulative incidence #Proportional hazards model #Ionizing radiation #Cohort #Leukemia #Cohort study #Demography #Internal medicine #Irradiation
19. JAK3 mutants transform hematopoietic cells through JAK1 activation, causing T-cell acute lymphoblastic leukemia in a mouse model
    2014/09/06 by Sandrine Degryse, Charles E. de Bock, Luk Cox +13 · 26 citations
    Medicine · #Acute Lymphoblastic Leukemia research #Biology #Cancer research #Chronic Myeloid Leukemia Treatments #Gene #Genetics #Haematopoiesis #Hematopoietic cell #Immunology #Leukemia #Lymphoblastic Leukemia #Mutant #Myeloproliferative Neoplasms: Diagnosis and Treatment #Stem cell
20. Phase 2 trial of CPX-351, a fixed 5:1 molar ratio of cytarabine/daunorubicin, vs cytarabine/daunorubicin in older adults with untreated AML
    2014/04/01 by Jeffrey E. Lancet, Jorge E. Cortes, Jörge E. Cortes +13 · 31 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Acute Myeloid Leukemia Research #Advanced biosensing and bioanalysis techniques #Cytarabine #Daunorubicin #Gastroenterology #Histone Deacetylase Inhibitors Research #Internal medicine #Leukemia #Medicine #Oncology
21. How we treat Richter syndrome
    2014/01/14 by Sameer A. Parikh, Neil E. Kay, Tait D. Shanafelt · 25 citations
    Medicine · #Advanced Breast Cancer Therapies #Aggressive lymphoma #Alemtuzumab #CDKN2A #Cancer #Chronic Lymphocytic Leukemia Research #Chronic lymphocytic leukemia #Diffuse large B-cell lymphoma #Internal medicine #Leukemia #Lymphoma #Lymphoma Diagnosis and Treatment #Medicine #Oncology #Rituximab #Transplantation
22. Leukemia cell–targeted STAT3 silencing and TLR9 triggering generate systemic antitumor immunity
    2013/10/30 by Dewan Md Sakib Hossain, Cedric Dos Santos, Cédric Dos Santos +16 · 26 citations
    Immunology and Microbiology · Medicine · #Biology #Cancer research #Cytokine Signaling Pathways and Interactions #DNA methylation #Immune Cell Function and Interaction #Immune Response and Inflammation #Immune system #Immunology #Leukemia #TLR9
23. FLT3tyrosine kinase inhibitors in acute myeloid leukemia: clinical implications and limitations
    2013/04/30 by Sabine Käyser, Mark J. Levis · 1 citation
    Medicine · #Acute Myeloid Leukemia Research #Chronic Myeloid Leukemia Treatments #Chronic Lymphocytic Leukemia Research #Myeloid leukemia #Tyrosine kinase #Medicine #Fms-Like Tyrosine Kinase 3 #Receptor tyrosine kinase #Cancer research #Drug resistance #Targeted therapy #Tyrosine-kinase inhibitor #Leukemia #CD135 #Mutation #Oncology #Pharmacology #Immunology #Gene #Internal medicine #Biology #Receptor #Cancer #Genetics
24. Integrin alpha4 blockade sensitizes drug resistant pre-B acute lymphoblastic leukemia to chemotherapy
    2013/01/15 by Yao-Te Hsieh, Eun Ji Gang, Huimin Geng +25 · 27 citations
    Medicine · #Acute Myeloid Leukemia Research #Acute lymphocytic leukemia #Blockade #Cancer research #Cell Adhesion Molecules Research #Chemotherapy #Chemotherapy regimen #Chronic Myeloid Leukemia Treatments #Drug #Immunology #Integrin #Internal medicine #Leukemia #Lymphoblastic Leukemia #Medicine #Pharmacology #Receptor
25. Lysosomal disruption preferentially targets acute myeloid leukemia cells and progenitors
    2012/12/03 by Mahadeo A. Sukhai, Swayam Prabha, Rose Hurren +44 · 25 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Autophagy in Disease and Therapy #Biochemistry #Biology #Cancer research #Cathepsin #Cell biology #Cellular transport and secretion #Haematopoiesis #Immunology #LAMP1 #Leukemia #Lysosome #Myeloid leukemia #Progenitor cell #Protein Degradation and Inhibitors #Stem cell #Vacuole
26. How I treat relapsed childhood acute lymphoblastic leukemia
    2012/08/16 by Franco Locatelli, Martin Schrappe, Maria Ester Bernardo +1 · 28 citations
    Medicine · #Acute Lymphoblastic Leukemia research #Acute lymphocytic leukemia #Antigen #Chemotherapy #Childhood Cancer Survivors' Quality of Life #Hematopoietic Stem Cell Transplantation #Hematopoietic stem cell transplantation #Immunology #Immunophenotyping #Internal medicine #Leukemia #Lymphoblastic Leukemia #Medicine #Minimal residual disease #Oncology #Radiation therapy #Salvage therapy #Surgery #Transplantation
27. A record-based case–control study of natural background radiation and the incidence of childhood leukaemia and other cancers in Great Britain during 1980–2006
    2012/06/05 by G M Kendall, M P Little, Mark P. Little +12 · 2 citations
    Health Professions · Medicine · #Absolute risk reduction #Cancer #Cancer registry #Childhood cancer #Childhood leukaemia #Childhood leukemia #Cohort #Confidence interval #Confounding #Cumulative incidence #Demography #Effects of Radiation Exposure #Environmental health #Incidence (geometry) #Internal medicine #Leukemia #Medicine #Natural experiment #Pathology #Pediatrics #Population #Radiation Dose and Imaging #Radioactivity and Radon Measurements #Rate ratio #Relative risk #Residence
28. Fever in Cancer Treatment: Coley's Therapy and Epidemiologic Observations
    2012/03/01 by Gunver S. Kienle · 1 citation
    Medicine · #Cancer #Cervical Cancer and HPV Research #Dermatology #Disease #Epidemiology #Hematological disorders and diagnostics #Hepatitis B Virus Studies #Immunology #Internal medicine #Leukemia #Medicine #Oncology #Pathology #Sarcoma
29. Flowcytometric Immunophenotypic Profile of Acute Leukemia: Mansoura Experience
    2011/09/20 by Dalia A. Salem, Dalia Salem, Sherin M. Abd El-Aziz · 1 citation
    Medicine · #Acute Lymphoblastic Leukemia research #Acute Myeloid Leukemia Research #Acute leukemia #Acute myeloblastic leukemia #Antigen #Biology #CD19 #CD20 #CD34 #CD5 #Genetics #Immunology #Immunophenotyping #Leukemia #Medicine #Myeloproliferative Neoplasms: Diagnosis and Treatment #Pathology
30. Antineoplastic Mechanisms of Niclosamide in Acute Myelogenous Leukemia Stem Cells: Inactivation of the NF-κB Pathway and Generation of Reactive Oxygen Species
    2010/03/09 by Yanli Jin, Zhongzheng Lu, Ke Ding +7 · 26 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Apoptosis #Biochemistry #Biology #Cancer research #Chemistry #Cytokine Signaling Pathways and Interactions #Histone Deacetylase Inhibitors Research #Immunology #Leukemia #Medicine #NF-κB Signaling Pathways #Niclosamide #Pharmacology #Reactive oxygen species

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