- Neighborhood opportunity and cellular senescence in a national sample of U.S. adults
2026/03/17 by Mariana Rodrigues, Jemar R. Bather, Alisha A. Crump +5 · 1 voice
Environmental Science · Medicine · Social Sciences · #Ageing #Biomarker #CDKN2A #Cellular Aging #Cellular senescence #Health disparities and outcomes #Health, Environment, Cognitive Aging #Life course approach #Senescence #Telomeres, Telomerase, and Senescence #Transcriptome
- A comprehensive genomic study of 390 H3F3A-mutant pediatric and adult diffuse high-grade gliomas, CNS WHO grade 4
2023/07/31 by Erik A. Williams, Priscilla K. Brastianos, Hiroaki Wakimoto +5 · 23 citations
Medicine · #Biology #CDKN2A #Cancer #Cancer research #Cohort #Gastroenterology #Gene #Genetics #Glioma #Glioma Diagnosis and Treatment #Internal medicine #Medicine #Mutant #Neurofibromatosis and Schwannoma Cases #Oncology #Pathology
- High-grade glioma with pleomorphic and pseudopapillary features (HPAP): a proposed type of circumscribed glioma in adults harboring frequent TP53 mutations and recurrent monosomy 13
2022/02/01 by Drew Pratt, Zied Abdullaev, Antonios Papanicolau‐Sengos +25 · 21 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Astrocytoma #Biology #CDKN2A #Cancer #Cancer Genomics and Diagnostics #Cancer research #Chromosome #DNA methylation #Epigenetics and DNA Methylation #Gene #Genetics #Glioma #Glioma Diagnosis and Treatment #Karyotype #Medicine #Monosomy #Oligodendroglioma #Pathology #Pleomorphic xanthoastrocytoma
- CDKN2A/B T2D Genome-Wide Association Study Risk SNPs Impact Locus Gene Expression and Proliferation in Human Islets
2018/02/06 by Yahui Kong, Rohit B. Sharma, Socheata Ly +4 · 26 citations
Biochemistry, Genetics and Molecular Biology · #Allele #Biology #CDKN2A #Cancer research #Cancer-related molecular mechanisms research #Candidate gene #Epigenetics and DNA Methylation #Gene #Gene knockdown #Genetics #Genome-wide association study #Genotype #Locus (genetics) #RNA modifications and cancer #SNP #Single-nucleotide polymorphism
- Molecular profiling of neuroendocrine malignancies to identify prognostic and therapeutic markers: a Fox Chase Cancer Center Pilot Study
2016/08/01 by Namrata Vijayvergia, Patrick M. Boland, Patrick M Boland +13 · 25 citations
Medicine · #Biology #CDKN2A #Cancer #Cancer research #Colorectal cancer #Genetics #Internal medicine #KRAS #Lung Cancer Research Studies #Medicine #Neuroendocrine Tumor Research Advances #Neuroendocrine differentiation #Neuroendocrine tumors #Oncology #PTEN #Pancreatic cancer #Pathology #Thyroid Cancer Diagnosis and Treatment
- Loss-of-Function Mutations in the Cell-Cycle Control Gene CDKN2A Impact on Glucose Homeostasis in Humans
2015/11/05 by Aparna Pal, Thomas P. Potjer, Soren K. Thomsen +16 · 23 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Biology #CDKN2A #Cancer research #Endocrinology #Epigenetics and DNA Methylation #Gene #Gene knockdown #Genetics #Genetics and Neurodevelopmental Disorders #Glucose homeostasis #Haploinsufficiency #Insulin #Insulin resistance #Internal medicine #Medicine #Pancreatic function and diabetes #Phenotype
- Integrated analysis of pediatric glioblastoma reveals a subset of biologically favorable tumors with associated molecular prognostic markers
2015/03/09 by Andrey Korshunov, Marina Ryzhova, Volker Hovestadt +19 · 28 citations
Medicine · #Astrocytoma #Biology #CDKN2A #Cancer research #DNA methylation #Gene #Genetics #Glioma #Glioma Diagnosis and Treatment #IDH1 #Internal medicine #Medicine #Methylation #Mutation #Neuroblastoma Research and Treatments #Oncology #Pancreatic and Hepatic Oncology Research #Pathology #Pleomorphic xanthoastrocytoma
- How we treat Richter syndrome
2014/01/14 by Sameer A. Parikh, Neil E. Kay, Tait D. Shanafelt · 25 citations
Medicine · #Advanced Breast Cancer Therapies #Aggressive lymphoma #Alemtuzumab #CDKN2A #Cancer #Chronic Lymphocytic Leukemia Research #Chronic lymphocytic leukemia #Diffuse large B-cell lymphoma #Internal medicine #Leukemia #Lymphoma #Lymphoma Diagnosis and Treatment #Medicine #Oncology #Rituximab #Transplantation
- JAK mutations in high-risk childhood acute lymphoblastic leukemia
2009/05/22 by Charles G. Mullighan, Jinghui Zhang, Richard C. Harvey +21 · 29 citations
Medicine · #ABL #Acute Lymphoblastic Leukemia research #Biology #CDKN2A #Cancer research #Chronic Myeloid Leukemia Treatments #Gene #Genetics #JAK-STAT signaling pathway #Janus kinase #Leukemia #Mutation #Myeloproliferative Neoplasms: Diagnosis and Treatment #Signal transduction #Tyrosine kinase
- Identification of differentially expressed genes in HPV-positive and HPV-negative oropharyngeal squamous cell carcinomas
2006/11/02 by Ivan Martinez, Iván Martínez, Jun Wang +3 · 5 citations
Biochemistry, Genetics and Molecular Biology · #Biology #CDKN2A #Cancer research #Cancer-related gene regulation #Cell #Cell cycle #Downregulation and upregulation #Gene #Gene expression #Genetics #NF-κB Signaling Pathways #RNA modifications and cancer