- CAR T cells: Building on the CD19 paradigm
2021/07/02 by Anat Globerson Levin, Isabelle Rivière, Zelig Eshhar +1 · 25 citations
Engineering · Immunology and Microbiology · Medicine · #Antigen #Biology #CAR-T cell therapy research #CD19 #Cancer immunotherapy #Cell biology #Chimeric antigen receptor #Immune Cell Function and Interaction #Immune system #Immunology #Immunotherapy #Major histocompatibility complex #Nanowire Synthesis and Applications #T cell
- CAR‐T Cell Therapy in Diffuse Large B Cell Lymphoma: Hype and Hope
2019/03/22 by Georg Hopfinger, Ulrich Jäger, Nina Worel · 1 citation
Medicine · Biochemistry, Genetics and Molecular Biology · Engineering · #CAR-T cell therapy research #Virus-based gene therapy research #Integrated Circuits and Semiconductor Failure Analysis #Medicine #Chimeric antigen receptor #Cytokine release syndrome #Lymphoma #Hematopoietic stem cell transplantation #Cell therapy #Clinical trial #Oncology #Transplantation #Immunotherapy #Adverse effect #Blinatumomab #Immunology #Internal medicine #Stem cell #CD19 #Antigen #Immune system #Biology
- Evolution of chimeric antigen receptor (CAR) T cell therapy: current status and future perspectives
2019/03/04 by Young-Ho Lee, Chan Hyuk Kim · 1 citation
Engineering · Medicine · #Advancements in Semiconductor Devices and Circuit Design #Antigen #Bioinformatics #Biology #CAR-T cell therapy research #CD19 #Cancer research #Cell #Cell therapy #Chimeric antigen receptor #Food and drug administration #Genetics #Immune system #Immunology #Medicine #Nanowire Synthesis and Applications #Pharmacology #T cell
- Resistance to anti-CD19/CD3 BiTE in acute lymphoblastic leukemia may be mediated by disrupted CD19 membrane trafficking
2016/10/26 by Friederike Braig, Anna Brandt, Mariele Goebeler +9 · 28 citations
Medicine · #Acute Lymphoblastic Leukemia research #Acute lymphocytic leukemia #Antigen #Blinatumomab #CAR-T cell therapy research #CD19 #Cancer research #Immunology #Leukemia #Lymphoblastic Leukemia #Medicine #Neuroblastoma Research and Treatments
- Persistence of long-lived plasma cells and humoral immunity in individuals responding to CD19-directed CAR T-cell therapy
2016/05/11 by Vijay Bhoj, Vijay G. Bhoj, Dimitrios Arhontoulis +24 · 28 citations
Immunology and Microbiology · Medicine · #Antibody #Biology #Biosimilars and Bioanalytical Methods #CAR-T cell therapy research #CD19 #Humoral immunity #Immune system #Immunity #Immunology #Medicine #Persistence (discontinuity) #Plasma cell #Virology
- IL-10–Producing Regulatory B Cells in the Pathogenesis of Chronic Hepatitis B Virus Infection
2012/09/13 by Abhishek Das, Gidon Ellis, Celeste Pallant +18 · 26 citations
Immunology and Microbiology · Medicine · #Antibody #B cell #Biology #CD19 #CD24 #CD34 #CD38 #CD8 #Cell #Ex vivo #Hepatitis B #Hepatitis B Virus Studies #Hepatitis B virus #Immune Cell Function and Interaction #Immune system #Immunology #Immunotherapy and Immune Responses #In vivo #Interleukin 10 #Pathogenesis #Regulatory B cells #Stem cell #T cell #Virology #Virus
- Flowcytometric Immunophenotypic Profile of Acute Leukemia: Mansoura Experience
2011/09/20 by Dalia A. Salem, Dalia Salem, Sherin M. Abd El-Aziz · 1 citation
Medicine · #Acute Lymphoblastic Leukemia research #Acute Myeloid Leukemia Research #Acute leukemia #Acute myeloblastic leukemia #Antigen #Biology #CD19 #CD20 #CD34 #CD5 #Genetics #Immunology #Immunophenotyping #Leukemia #Medicine #Myeloproliferative Neoplasms: Diagnosis and Treatment #Pathology
- Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19
2010/07/29 by James N. Kochenderfer, Wyndham H. Wilson, John E. Janik +12 · 39 citations
Biochemistry, Genetics and Molecular Biology · Engineering · Medicine · #Adoptive cell transfer #Antibody #Antigen #B cell #Biology #Bone marrow #CAR-T cell therapy research #CD19 #Cancer research #Chimeric antigen receptor #Immune system #Immunology #Lymphoma #Medicine #Nanowire Synthesis and Applications #T cell #Viral Infectious Diseases and Gene Expression in Insects