- Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo
2017/08/28 by Max Medina-Ramírez, Fernando Garcés, Fernando Garces +35 · 30 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Immunology and Microbiology · Medicine · #Antibody #Biochemistry #Biology #Cell biology #Chemistry #Epitope #Genetics #Glycoprotein #Glycosylation and Glycoproteins Research #Gp41 #HIV Research and Treatment #Immunology #In vitro #In vivo #Molecular biology #Monoclonal and Polyclonal Antibodies Research #Neutralizing antibody #Trimer #Virology
- Engineering HIV envelope protein to activate germline B cell receptors of broadly neutralizing anti-CD4 binding site antibodies
2013/03/25 by Andrew T. McGuire, Sam Hoot, Anita M. Dreyer +11 · 34 citations
Immunology and Microbiology · #AIDS Vaccines #Antibody #Biology #Epitope #Gene #Genetics #Germline #Glycoprotein #Glycosylation #Gp41 #HIV Research and Treatment #HIV vaccine #Human immunodeficiency virus (HIV) #Immune Cell Function and Interaction #Immunology #Molecular biology #Neutralizing antibody #T-cell and B-cell Immunology #Vaccine trial #Virology #Virus
- A region of the C-terminal tail of the gp41 envelope glycoprotein of human immunodeficiency virus type 1 contains a neutralizing epitope: evidence for its exposure on the surface of the virion
2003/02/25 by Susan M. Cleveland, S. Matthew Cleveland, Lesley McLain +5 · 18 citations
Immunology and Microbiology · Medicine · #Antibody #Biology #Epitope #Glycoprotein #Gp41 #HIV Research and Treatment #Herpesvirus Infections and Treatments #Immunology #Linear epitope #Molecular biology #Monoclonal and Polyclonal Antibodies Research #Monoclonal antibody #Polyclonal antibodies #Viral envelope #Virology #Virus