- Fifty years of DNA “Breathing”: Reflections on old and new approaches
2013/07/10 by Peter H. von Hippel, Neil P. Johnson, Andrew H. Marcus · 27 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · #Base pair #Biochemistry #Biology #Biophysics #Chemical physics #Chemistry #Computational biology #DNA #DNA and Nucleic Acid Chemistry #DNA sequencing #Duplex (building) #Gene #Genome #Human genome #RNA Interference and Gene Delivery #RNA and protein synthesis mechanisms #Sequence (biology)
- DNA Base Identification by Electron Microscopy
2012/10/01 by David C. Bell, W. Kelley Thomas, K Murtagh +4 · 1 citation
Biochemistry, Genetics and Molecular Biology · Environmental Science · Chemistry · #Advanced Electron Microscopy Techniques and Applications #RNA and protein synthesis mechanisms #Bacteriophages and microbial interactions #DNA #Base pair #DNA sequencing #Nucleobase #Molecule #Chemistry #Sequencing by ligation #Biophysics #Computational biology #Nanotechnology #Biology #Biochemistry #Base sequence #Materials science #Genomic library
- Mechanistic details of the DNA recognition by the Dnmt1 DNA methyltransferase
2012/05/25 by Pavel Bashtrykov, Sergey Ragozin, Albert Jeltsch · 7 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · #Base (topology) #Base pair #Biology #Chemistry #CpG site #DNA #DNA and Nucleic Acid Chemistry #DNA methylation #DNA methyltransferase #DNMT1 #Endonuclease #Epigenetics and DNA Methylation #Gene #Gene expression #Genetics #Genomics and Chromatin Dynamics #Methylation #Methyltransferase
- On the page number of RNA secondary structures with pseudoknots
2011/12/09 by Peter Clote, Stefan Dobrev, Iván Dotú +5 · 1 citation
Biochemistry, Genetics and Molecular Biology · Mathematics · #Algorithm #Base (topology) #Base pair #Biology #Combinatorics #Computation #Constraint (computer-aided design) #Discrete mathematics #Disjoint sets #Gene #Genetics #Geometry #Mathematics #Pairwise comparison #RNA #RNA Research and Splicing #RNA and protein synthesis mechanisms #RNA modifications and cancer
- Human Genome Sequencing Using Unchained Base Reads on Self-Assembling DNA Nanoarrays
2009/11/05 by Radoje Drmanac, Andrew B. Sparks, Matthew J. Callow +62 · 2 citations
Biochemistry, Genetics and Molecular Biology · #Advanced biosensing and bioanalysis techniques #RNA and protein synthesis mechanisms #Gene expression and cancer classification #Human genome #DNA #Genome #DNA sequencing #Base (topology) #Computational biology #Base pair #Biology #Genetics #Gene
- Continuous base identification for single-molecule nanopore DNA sequencing
2009/02/22 by James Clarke, Hai‐Chen Wu, Hai-Chen Wu +5 · 7 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Engineering · #Adapter (computing) #Advanced biosensing and bioanalysis techniques #Base pair #Base sequence #Biochemistry #Biology #Biophysics #Chemistry #Cleave #Computational biology #Computer science #Cytosine #DNA #DNA polymerase #DNA sequencing #Exonuclease #Gene #Genomic library #Materials science #Nanopore #Nanopore and Nanochannel Transport Studies #Nanopore sequencing #Nanotechnology #Nucleic acid #Nucleotide #RNA modifications and cancer #Sequencing by ligation #Thymine
- The Electronic Properties of DNA Bases
2007/09/03 by Mingsheng Xu, Robert G. Endres, Yasuhiko Arakawa · 2 citations
Engineering · Biochemistry, Genetics and Molecular Biology · Chemistry · #Nanopore and Nanochannel Transport Studies #Advanced biosensing and bioanalysis techniques #DNA and Nucleic Acid Chemistry #DNA #Guanine #Thymine #Density functional theory #Base pair #Scanning tunneling microscope #Nucleobase #Cytosine #Molecule #Quantum tunnelling #A-DNA #DNA sequencing #Chemical physics #Chemistry #Electronic structure #Nanotechnology #Crystallography #Materials science #Computational chemistry #Nucleotide #Optoelectronics #Biochemistry #Gene
- Thermal Denaturation of Fluctuating DNA Driven by Bending Entropy
2006/12/31 by J. Palmeri, John Palmeri, Manoel Manghi +3 · 1 citation
Biochemistry, Genetics and Molecular Biology · Chemistry · Engineering · Physics and Astronomy · #Base pair #Chemistry #Configuration entropy #DNA #DNA and Nucleic Acid Chemistry #Denaturation (fissile materials) #Electrostatics and Colloid Interactions #Entropy (arrow of time) #Materials science #Molecular physics #Molecule #Nanopore and Nanochannel Transport Studies #Persistence length #Physics #Quantum mechanics #RADIUS #Thermal #Thermal fluctuations #Thermodynamics #cond-mat.soft #cond-mat.stat-mech #physics.bio-ph
- The mechanism of topoisomerase I poisoning by a camptothecin analog
2002/11/08 by Bart L. Staker, Kathryn A. Hjerrild, M.D. Feese +3 · 1 citation
Biochemistry, Genetics and Molecular Biology · Pharmacology, Toxicology and Pharmaceutics · Medicine · Chemistry · #Cancer therapeutics and mechanisms #Bioactive Compounds and Antitumor Agents #Neutropenia and Cancer Infections #Camptothecin #Topoisomerase #Topotecan #DNA #Binding site #Chemistry #Stereochemistry #Biochemistry #Cleavage (geology) #Intercalation (chemistry) #Base pair #Enzyme #Biophysics #Biology #Genetics
- Divergence between samples of chimpanzee and human DNA sequences is 5%, counting indels
2002/10/04 by Roy J. Britten · 2 citations
Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · #Chromosomal and Genetic Variations #RNA and protein synthesis mechanisms #Genomics and Phylogenetic Studies #Indel #GenBank #Human genome #Genetics #Biology #Genome #DNA #Divergence (linguistics) #Chromosome #DNA sequencing #Sequence (biology) #Base pair #Computational biology #Gene #Single-nucleotide polymorphism
- Molecular Genetic Analyses of the Tyrolean Ice Man
1994/06/17 by Oliva Handt, Martin Richards, Marion Trommsdorff +10 · 3 citations
Biochemistry, Genetics and Molecular Biology · #Forensic and Genetic Research #Genetic diversity and population structure #Identification and Quantification in Food #Hypervariable region #Mitochondrial DNA #Biology #mtDNA control region #DNA #Genetics #DNA sequencing #Sequence (biology) #Genome #Base pair #Evolutionary biology #Molecular biology #Gene #Haplotype #Genotype
- Condensation of DNA by multivalent cations: Considerations on mechanism
1991/11/01 by Victor A. Bloomfield · 38 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Environmental Science · #Aqueous solution #Bacteriophages and microbial interactions #Base pair #Chemical physics #Chemistry #Condensation #Crystallography #DNA #DNA and Nucleic Acid Chemistry #DNA condensation #Electrostatics and Colloid Interactions #Lysis #Micelle #Molecule #Organic chemistry #Physical chemistry #Physics #Thermodynamics
- Directional cloning of DNA fragments at a large distance from an initial probe: a circularization method.
1984/11/01 by F S Collins, S M Weissman · 1 citation
Biochemistry, Genetics and Molecular Biology · Environmental Science · #Animal Genetics and Reproduction #Bacteriophages and microbial interactions #Base pair #Biology #Circular bacterial chromosome #Complementary DNA #Cosmid #DNA #Gene #Genetics #Genomic library #In vitro recombination #Molecular biology #Molecular cloning #Multiple cloning site #RNA and protein synthesis mechanisms #Recombinant DNA #Restriction enzyme #Sticky and blunt ends #genomic DNA
- Nucleotide sequence of bacteriophage λ DNA
1982/12/01 by Frederick Sanger, F. Sanger, Alan Coulson +6 · 3 citations
Biochemistry, Genetics and Molecular Biology · #Bacterial Genetics and Biotechnology #Base pair #Biology #Coding region #Computational biology #Consensus sequence #DNA #DNA sequencing #Gene #Genetic code #Genetics #Genomics and Phylogenetic Studies #Nucleic acid sequence #Open reading frame #Peptide sequence #RNA and protein synthesis mechanisms #Reading frame #Sequence (biology) #Stop codon
- Complete sequence of bovine mitochondrial DNA conserved features of the mammalian mitochondrial genome
1982/04/01 by S. Anderson, Stephen K. Anderson, M.H.L. de Bruijn +8 · 14 citations
Biochemistry, Genetics and Molecular Biology · #Base pair #Biology #DNA #Gene #Genetics #Genome #Genomics and Phylogenetic Studies #Homology (biology) #Human genome #MT-RNR1 #Mitochondrial DNA #Mitochondrial Function and Pathology #Molecular biology #Nucleic acid sequence #RNA #RNA and protein synthesis mechanisms #Ribosomal RNA #Stop codon #Transfer RNA #mtDNA control region
- Polymorphism in mitochondrial DNA of humans as revealed by restriction endonuclease analysis.
1980/06/01 by Wesley M. Brown · 10 citations
Biochemistry, Genetics and Molecular Biology · #Genetic diversity and population structure #Forensic and Genetic Research #Genomics and Phylogenetic Studies #Mitochondrial DNA #Restriction enzyme #Biology #Genetics #Homo sapiens #Population #Restriction fragment length polymorphism #Population genetics #Base pair #DNA #Evolutionary biology #Polymerase chain reaction #Gene
- Rapid evolution of animal mitochondrial DNA.
1979/04/01 by Wesley M. Brown, M George, Alex C. C. Wilson · 22 citations
Biochemistry, Genetics and Molecular Biology · #Genomics and Phylogenetic Studies #Mitochondrial Function and Pathology #RNA and protein synthesis mechanisms #Mitochondrial DNA #Biology #DNA #Nuclear DNA #Genetics #Heavy strand #Base pair #Baboon #Genome #Restriction enzyme #Molecular evolution #Molecular biology #Gene #Transfer RNA #RNA
- A new method for sequencing DNA.
1977/02/01 by Allan M. Maxam, Wendy V. Gilbert · 23 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · #Chemical Synthesis and Analysis #DNA and Nucleic Acid Chemistry #Advanced biosensing and bioanalysis techniques #DNA #Cleave #Base pair #DNA sequencing #Single molecule real time sequencing #Sequencing by hybridization #Biology #Gel electrophoresis #Chemistry #Biochemistry #Molecular biology #DNA sequencer
- DNA sequence analysis: a general, simple and rapid method for sequencing large oligodeoxyribonucleotide fragments by mapping
1974/01/01 by Ernest Jay, Robert A. Bambara, R. Padmanabhan +1 · 1 citation
Biochemistry, Genetics and Molecular Biology · #DNA and Nucleic Acid Chemistry #Advanced biosensing and bioanalysis techniques #RNA and protein synthesis mechanisms #Oligonucleotide #Biology #Nucleotide #Sequence (biology) #DNA #Nucleic acid sequence #Sequence analysis #Bacteriophage #DNA sequencing #Molecular biology #Base pair #Genetics #Biochemistry #Computational biology #Gene
- Nucleotide Sequence from the Coat Protein Cistron of R17 Bacteriophage RNA
1969/09/01 by J. M. ADAMS, Jerry M. Adams, Peter Jeppesen +5 · 3 citations
Biochemistry, Genetics and Molecular Biology · Environmental Science · #Bacteriophage #Bacteriophages and microbial interactions #Base pair #Biology #Cistron #Coat protein #Escherichia coli #Gene #Genetic code #Genetics #Nucleotide #RNA #RNA and protein synthesis mechanisms #RNA modifications and cancer #Sequence (biology) #Virology