- Common Polymorphisms ofCYP2B6Influence Stereoselective Bupropion Disposition
2018/05/14 by Evan D. Kharasch, Amanda Crafford · 9 citations
Chemistry · Medicine · Pharmacology, Toxicology and Pharmaceutics · #Biochemistry #Bupropion #CYP2B6 #CYP2C19 #CYP3A4 #Chemistry #Cytochrome P450 #Enzyme #Hydroxylation #Medicine #Metabolism #Pharmacogenetics and Drug Metabolism #Pharmacology #Pharmacology and Obesity Treatment #Poisoning and overdose treatments #Smoking cessation
- Human Collagen Prolyl 4-Hydroxylase Is Activated by Ligands for Its Iron Center
2016/05/16 by James D. Vasta, Ronald T. Raines · 13 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · #Active center #Amino acid #Biochemistry #Cancer, Hypoxia, and Metabolism #Carboxylate #Chemistry #Cofactor #Dioxygenase #Enzyme #Hydroxylation #Metal-Catalyzed Oxygenation Mechanisms #Proline #S100 Proteins and Annexins #Scurvy #Stereochemistry #Vitamin C
- SIRT1 deacetylates and stabilizes hypoxia-inducible factor-1α (HIF-1α) via direct interactions during hypoxia
2015/05/13 by Hyun-Yoo Joo, Miyong Yun, Jaemin Jeong +11 · 27 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Acetylation #Biochemistry #Biology #Cancer, Hypoxia, and Metabolism #Cell #Cell biology #Chemistry #Downregulation and upregulation #Endocrinology #Endoplasmic Reticulum Stress and Disease #Enzyme #GLUT1 #Gene #Glucose transporter #Hydroxylation #Hypoxia (environmental) #Hypoxia-Inducible Factor 1 #Hypoxia-inducible factors #Oxygen #Proteasome #Sirtuin 1 #Sirtuins and Resveratrol in Medicine
- Membrane protein complexes catalyze both 4- and 3-hydroxylation of cinnamic acid derivatives in monolignol biosynthesis
2011/12/12 by Hsi-Chuan Chen, Quanzi Li, Christopher M. Shuford +4 · 28 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · #Biochemistry #Biosynthesis #Carbohydrate Chemistry and Synthesis #Chemistry #Cinnamic acid #Enzyme #Hydroxylation #Microbial metabolism and enzyme function #Monolignol #Organic chemistry #Plant Gene Expression Analysis
- A new set of molecular mechanics parameters for hydroxyproline and its use in molecular dynamics simulations of collagen‐like peptides
2005/09/16 by Sanghyun Park, Randall J. Radmer, Teri E. Klein +1 · 1 citation
Materials Science · Biochemistry, Genetics and Molecular Biology · Chemistry · #Collagen: Extraction and Characterization #Chemical Synthesis and Analysis #Hydroxyproline #Molecular mechanics #Hydroxylation #Molecular dynamics #Chemistry #Context (archaeology) #Proline #Collagen helix #Monomer #Computational chemistry #Triple helix #Stereochemistry #Amino acid #Biochemistry #Enzyme #Biology #Organic chemistry #Polymer
- Arabidopsis CYP735A1 and CYP735A2 Encode Cytokinin Hydroxylases That Catalyze the Biosynthesis of trans-Zeatin
2004/07/27 by Kentaro Takei, Tomoyuki Yamaya, Hitoshi Sakakibara · 29 citations
Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · Chemistry · #Arabidopsis #Auxin #Biochemistry #Biology #Biosynthesis #Chemistry #Cytokinin #Enzyme #Gene #Hydroxylation #Mutant #Nucleoside #Nucleotide #Photosynthetic Processes and Mechanisms #Plant Molecular Biology Research #Plant biochemistry and biosynthesis #Stereochemistry #Zeatin
- The active sites of molybdenum- and tungsten-containing enzymes
1998/04/01 by J McMaster, Jonathan McMaster, John H. Enemark +1 · 1 citation
Biochemistry, Genetics and Molecular Biology · Chemistry · Energy · #Active site #Biochemistry #Chemistry #Cofactor #Enzyme #Hydroxylation #Inorganic chemistry #Metal-Catalyzed Oxygenation Mechanisms #Metalloenzymes and iron-sulfur proteins #Molybdenum #Molybdenum cofactor #Organic chemistry #Pterin #RNA modifications and cancer #Stereochemistry #Tungsten
- Electron Leakage from the Adrenal-Cortex Mitochondrial P450Scc and P450C11 Systems: NADPH and Steroid Dependence
1995/03/01 by R. Rapoport, D. Sklan, Israel Hanukoglu +1 · 1 citation
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · Pharmacology, Toxicology and Pharmaceutics · #Adrenal cortex #Biochemistry #Biology #Chemistry #Cholesterol side-chain cleavage enzyme #Corticosterone #Cytochrome P450 #Endocrinology #Enzyme #Hormonal and reproductive studies #Hormone #Hydroxylation #Internal medicine #Medicine #Pharmacogenetics and Drug Metabolism #Photochemistry #Pregnenolone #Receptor Mechanisms and Signaling #Steroid
- Bile acid synthesis from cholesterol: regulatory and auxiliary pathways
1994/12/01 by Norman B. Javitt · 2 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Bile acid #Biochemistry #Biology #CYP27A1 #CYP8B1 #Cancer, Lipids, and Metabolism #Chemistry #Chenodeoxycholic acid #Cholesterol #Cholesterol 7 alpha-hydroxylase #Cholesterol and Lipid Metabolism #Cholic acid #Drug Transport and Resistance Mechanisms #Enterohepatic circulation #Enzyme #Hormone #Hydroxylation #Lipoprotein #Reverse cholesterol transport #Steroid #Sterol
- Asymmetric hydroxylation of enolates with N-sulfonyloxaziridines
1992/07/01 by Franklin A. Davis, Bang Chi Chen · 2 citations
Chemistry · #Synthesis and Catalytic Reactions #Asymmetric Synthesis and Catalysis #Chemical Reaction Mechanisms #Chemistry #Hydroxylation #Organic chemistry #Combinatorial chemistry #Stereochemistry #Enzyme
- cis-Hydroxylation of a Synthetic Steroid Intermediate with Iodine, Silver Acetate and Wet Acetic Acid
1958/01/01 by R. B. Woodward, Frederick V. Brutcher · 1 citation
Biochemistry, Genetics and Molecular Biology · Chemistry · #Steroid Chemistry and Biochemistry #Oxidative Organic Chemistry Reactions #Analytical Chemistry and Chromatography #Citation #Acetic acid #Icon #Computer science #Hydroxylation #Social media #Information retrieval #Chemistry #World Wide Web #Organic chemistry