31. Centriolar cap proteins CP110 and CPAP control slow elongation of microtubule plus ends
    2024/12/10 by Saishree S. Iyer, Fangrui Chen, Funso E. Ogunmolu +21 · 8 citations
    Biochemistry, Genetics and Molecular Biology · #Biochemistry #Biology #Cell #Cell biology #Cell cycle #Centriole #Centrosome #Ciliogenesis #Cilium #Genetic and Kidney Cyst Diseases #Microtubule #Microtubule and mitosis dynamics #Microtubule nucleation #Microtubule-associated protein #Nuclear Structure and Function
32. Cell–cell junctions in focus – imaging junctional architectures and dynamics at high resolution
    2024/10/15 by Vera Janssen, Stephan Huveneers · 1 voice · 2 citations
    Biochemistry, Genetics and Molecular Biology · Neuroscience · #Adherens junction #Advanced Electron Microscopy Techniques and Applications #Barrier Structure and Function Studies #Biology #Cadherin #Cell #Cell biology #Cell junction #Cellular Mechanics and Interactions #Cytoskeleton #Fluorescence #Fluorescence microscope #Live cell imaging #Microscopy
33. Lack of ceramide synthase 5 protects retinal ganglion cells from ocular hypertensive injury
    2024/08/27 by Jian Liu, Yiannis Koutalos, Jie Fan · 1 citation
    Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · Neuroscience · #Apoptosis #Biochemistry #Biology #Cell #Cell biology #Ceramide #Ceramide synthase #Chemistry #Enzyme #Glaucoma #Glaucoma and retinal disorders #Lipid signaling #Neuroscience #Ocular hypertension #Retinal #Retinal ganglion cell #Sleep and Wakefulness Research #Sphingolipid Metabolism and Signaling #Viability assay
34. The widespread vulnerability of Hydra oligactis to tumourigenesis confirms its value as a model for studying the effects of tumoural processes on the ecology and evolution of species
    2024/08/24 by Antoine M. Dujon, Justine Boutry, Sophie Tissot +5 · 1 voice · 1 citation
    Biochemistry, Genetics and Molecular Biology · Earth and Planetary Sciences · Environmental Science · #Biology #Cell #Computer science #Context (archaeology) #Ecology #Evolutionary biology #Evolutionary dynamics #Genetics #Lernaean Hydra #Marine Ecology and Invasive Species #Marine Invertebrate Physiology and Ecology #Multicellular organism #Myxozoan Parasites in Aquatic Species #Population #Vulnerability (computing)
35. Antibody-based near-infrared fluorogenic probes for wash-free imaging of cell-surface proteins
    2024/07/22 by Haoting Wang, Jiaqi Yan, Wenchao Wang +5 · 1 citation
    Biochemistry, Genetics and Molecular Biology · Chemistry · Engineering · #Advanced Fluorescence Microscopy Techniques #Antibody #Biochemistry #Biophysics #Cell #Chemistry #Click Chemistry and Applications #Computational biology #Immunology #Nanoplatforms for cancer theranostics #Nanotechnology #Surface protein #Virology
36. A Curated and Re-annotated Peripheral Blood Cell Dataset Integrating Four Public Resources
    2024/07/18 by Lu Gan, Gan, Lu, Xi Li +2 · 1 citation
    Biochemistry, Genetics and Molecular Biology · Medicine · #Biology #Blood groups and transfusion #Cancer Genomics and Diagnostics #Cell #Computational biology #Computer Vision and Pattern Recognition (cs.CV) #Computer science #FOS: Computer and information sciences #Genetics #Internal medicine #Medicine #Peripheral #Peripheral blood #Single-cell and spatial transcriptomics
37. Tetraspanin proteins in membrane remodeling processes
    2024/07/15 by Raviv Dharan, Raya Sorkin · 7 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Biochemistry #Biology #Caveolin-1 and cellular processes #Cell #Cell Adhesion Molecules Research #Cell biology #Computational biology #Membrane #Membrane protein #Platelet Disorders and Treatments #Tetraspanin
38. The tissue-resident regulatory T cell pool is shaped by transient multi-tissue migration and a conserved residency program
    2024/06/18 by Oliver T. Burton, Orian Bricard, Samar Tareen +15 · 2 voices · 32 citations
    Immunology and Microbiology · Medicine · #Atherosclerosis and Cardiovascular Diseases #Biology #Cell #Cell biology #FOXP3 #Gene #Genetics #Homing (biology) #IL-2 receptor #Immune Cell Function and Interaction #Immune system #Immunology #Lymphatic system #Medicine #Phenotype #Population #Regulatory T cell #T cell #T-cell and B-cell Immunology #T-cell receptor
39. DDX39B protects against sorafenib-induced ferroptosis by facilitating the splicing and cytoplasmic export of GPX4 pre-mRNA in hepatocellular carcinoma
    2024/05/01 by Qin Li, Hang Yuan, Gang Zhao +15 · 5 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Apoptosis #Biochemistry #Biology #Cancer #Cancer cell #Cancer research #Cell #Cell biology #Chemistry #Downregulation and upregulation #Enzyme #Ferroptosis and cancer prognosis #GPX4 #Gene #Genetics #Glutathione #Hepatocellular carcinoma #Liver cancer #Programmed cell death #RNA Research and Splicing #RNA modifications and cancer #Sorafenib
40. Metabolomics analysis revealed the neuroprotective role of 2-phosphoglyceric acid in hypoxic-ischemic brain damage through GPX4/ACSL4 axis regulation
    2024/03/31 by Haocong Chen, Yimingjiang Wusiman, Jing Zhao +7 · 7 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · Neuroscience · #Biochemistry #Bioinformatics #Biology #Brain damage #Cancer-related molecular mechanisms research #Cell #Cell damage #Chemistry #Endogeny #Hypoxia (environmental) #Internal medicine #Ischemia #Medicine #Metabolite #Metabolomics #Metabolomics and Mass Spectrometry Studies #Neuroprotection #Neuroscience #Oxygen #Pharmacology #RNA modifications and cancer
41. Serine Supports Epithelial and Immune Cell Function in Colitis
    2024/02/28 by Ji Dong K. Bai, Suchandrima Saha, Michael C. Wood +4 · 8 citations
    Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · Medicine · #Biochemistry #Biology #Cell #Cell biology #Colitis #Epithelium #Function (biology) #Helicobacter pylori-related gastroenterology studies #Immune system #Immunodeficiency and Autoimmune Disorders #Immunology #Inflammation #Inflammatory Bowel Disease #Medicine #Pathology #Phosphorylation #Serine
42. Transcriptomic analysis reveals ozone treatment delays kiwifruit postharvest softening by modulating cell wall metabolism
    2024/02/19 by Wang Yan, Yan Wang, Yaoxing Niu +3 · 6 citations
    Agricultural and Biological Sciences · Chemistry · Materials Science · #Biochemistry #Biology #Botany #Cell #Cell biology #Cell wall #Chemistry #Enzyme #Expansin #Food science #Gene #Gene expression #Nanocomposite Films for Food Packaging #Pectin #Pectinase #Pectinesterase #Polysaccharides and Plant Cell Walls #Postharvest #Postharvest Quality and Shelf Life Management #Ripening #Softening #Transcriptome #Xyloglucan
43. Phosphoinositide switches in cell physiology - From molecular mechanisms to disease
    2024/02/15 by Fabio Lolicato, Walter Nickel, Volker Haucke +1 · 8 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Biochemistry #Biology #Biophysics #Cell #Cell biology #Cell signaling #Cellular transport and secretion #Chemistry #Erythrocyte Function and Pathophysiology #Lipid bilayer #Membrane #Phosphatidylinositol #Protein Kinase Regulation and GTPase Signaling #Signal transduction
44. HuR–miRNA complex activates RAS GTPase RalA to facilitate endosome targeting and extracellular export of miRNAs
    2024/02/14 by Syamantak Ghosh, Sourav Hom Choudhury, Kamalika Mukherjee +1 · 7 citations
    Biochemistry, Genetics and Molecular Biology · #Biochemistry #Biology #Cell #Cell biology #ESCRT #Endocytic cycle #Endocytosis #Endosome #Enzyme #Extracellular #Extracellular vesicle #Extracellular vesicles in disease #GTPase #Gene #Intracellular #Lysosome #MicroRNA in disease regulation #Microvesicles #RNA Interference and Gene Delivery #Rab #Signal transduction #Small GTPase #microRNA
45. CAR-T cell manufacturing: Major process parameters and next-generation strategies
    2023/12/15 by Melanie Ayala Ceja, Mobina Khericha, Caitlin M. Harris +3 · 29 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · Engineering · Medicine · #Business #CAR-T cell therapy research #Cancer research #Cell #Chemistry #Chimeric antigen receptor #Computer science #Immune system #Immunology #Immunotherapy #Manufacturing process #Materials science #Medicine #Nanowire Synthesis and Applications #Process (computing) #Viral Infectious Diseases and Gene Expression in Insects
46. Pulses of RhoA signaling stimulate actin polymerization and flow in protrusions to drive collective cell migration
    2023/12/13 by Weiyi Qian, Naoya Yamaguchi, Patrycja Lis +2 · 1 voice · 9 citations
    Biochemistry, Genetics and Molecular Biology · #Actin #Biochemistry #Biology #Cell #Cell biology #Cell migration #Cellular Mechanics and Interactions #Filopodia #Hippo pathway signaling and YAP/TAZ #Lamellipodium #Microtubule and mitosis dynamics #Motility #Myosin #RHOA #Signal transduction #Zebrafish
47. Hypoxia-Responsive CAR-T Cells Exhibit Reduced Exhaustion and Enhanced Efficacy in Solid Tumors
    2023/10/24 by Xiuxiu Zhu, Jun Chen, Wuling Li +8 · 27 citations
    Chemistry · Immunology and Microbiology · Medicine · #Biochemistry #Biology #CAR-T cell therapy research #Cancer research #Cell #Cell biology #Cell growth #Chemistry #Chimeric antigen receptor #Cytotoxic T cell #Downregulation and upregulation #Hypoxia (environmental) #Immune Cell Function and Interaction #Immune system #Immunology #In vitro #Monoclonal and Polyclonal Antibodies Research #Oxygen #Reprogramming #T cell #Tumor cells #Tumor microenvironment
48. Joining forces: crosstalk between mechanosensitive PIEZO1 ion channels and integrin-mediated focal adhesions
    2023/09/29 by Delfine Cheng, Junfan Wang, Mingxi Yao +2 · 1 citation
    Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Biology #Blood properties and coagulation #Cell #Cell biology #Cellular Mechanics and Interactions #Chemistry #Crosstalk #Cytoskeleton #Erythrocyte Function and Pathophysiology #Extracellular matrix #Focal adhesion #Genetics #Integrin #Ion channel #Mechanosensitive channels #Mechanotransduction #PIEZO1 #Physics #Signal transduction
49. Targeting endothelial vascular cell adhesion molecule-1 in atherosclerosis: drug discovery and development of vascular cell adhesion molecule-1–directed novel therapeutics
    2023/08/18 by Jessica R Pickett, Yuao Wu, Lucia F Zacchi +3 · 27 citations
    Immunology and Microbiology · Medicine · #Atherosclerosis and Cardiovascular Diseases #Biochemistry #Bioinformatics #Biology #Cancer research #Cell #Cell Adhesion Molecules Research #Cell adhesion #Cell adhesion molecule #Cell biology #Drug #Drug development #Drug discovery #Function (biology) #ICAM-1 #Immunology #Medicine #Phagocytosis and Immune Regulation #Pharmacology #VCAM-1
50. Neural network-assisted single-molecule localization microscopy with a weak-affinity protein tag
    2023/08/18 by Soohyen Jang, Kaarjel K. Narayanasamy, Johanna V. Rahm +6 · 1 voice · 4 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · #Advanced Electron Microscopy Techniques and Applications #Advanced Fluorescence Microscopy Techniques #Artificial intelligence #Artificial neural network #Biochemistry #Biological system #Biology #Biophysics #Cell #Cell Image Analysis Techniques #Chemistry #Computer science #Endoplasmic reticulum #Fluorescence #Fluorescence microscope #Fluorescence recovery after photobleaching #Fluorescence-lifetime imaging microscopy #Live cell imaging #Microscopy #Optics #Photobleaching #Physics #Resolution (logic) #Super-resolution microscopy #Temporal resolution
51. ICAM-1 and VCAM-1: Gatekeepers in various inflammatory and cardiovascular disorders
    2023/07/11 by Varinder Singh, Rupinder Kaur, Pratima Kumari +3 · 31 citations
    Immunology and Microbiology · Medicine · #Atherosclerosis and Cardiovascular Diseases #Biology #Biomarkers in Disease Mechanisms #Cell #Cell Adhesion Molecules Research #Cell adhesion #Cell adhesion molecule #Endothelium #ICAM-1 #Immune system #Immunoglobulin superfamily #Immunology #Inflammation #Intercellular Adhesion Molecule-1 #Internal medicine #Medicine #VCAM-1
52. Distinct effects of heat shock temperatures on mitotic progression by influencing the spindle assembly checkpoint
    2023/06/18 by Saki Ota, Yui Tanaka, Y. Tanaka +5 · 4 citations
    Biochemistry, Genetics and Molecular Biology · #Biochemistry #Biology #Cell #Cell biology #Cell division #Cellular Mechanics and Interactions #Chromosome #Cytoskeleton #Heat shock proteins research #Kinetochore #Mad2 #Microtubule and mitosis dynamics #Mitosis #Mitotic exit #Mitotic index #Nocodazole #Spindle apparatus #Spindle checkpoint
53. Single-Cell and Spatial Transcriptomic Analysis of Human Skin Delineates Intercellular Communication and Pathogenic Cells
    2023/05/02 by Kim Thrane, Mårten C.G. Winge, M.C.G. Winge +26 · 15 citations
    Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · Medicine · #Biology #Cell #Cell biology #Computational biology #Gene #Gene expression #Genetics #Human skin #Intracellular #Single-cell and spatial transcriptomics #Skin Protection and Aging #T-cell and B-cell Immunology #Transcriptome
54. The human α cell in health and disease
    2023/04/28 by Yasminye D. Pettway, Yasminye D Pettway, Diane C Saunders +3 · 11 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Biology #Cell #Diabetes Management and Research #Diabetes and associated disorders #Disease #Endocrinology #Genetics #Internal medicine #Medicine #Pancreatic function and diabetes
55. Lung Remodeling Regions in Long-Term Coronavirus Disease 2019 Feature Basal Epithelial Cell Reprogramming
    2023/03/01 by Kangyun Wu, Yong Zhang, Stephen R. Austin +5 · 9 citations
    Medicine · #Biology #COVID-19 Clinical Research Studies #Cell #Coronavirus #Coronavirus disease 2019 (COVID-19) #Diffuse alveolar damage #Disease #Hyperplasia #Immune system #Immunology #Infectious disease (medical specialty) #Internal medicine #Lung #Medicine #Neonatal Respiratory Health Research #Pathology #Reprogramming #Respiratory Support and Mechanisms #Respiratory disease
56. PD-1 blockade and CDK4/6 inhibition augment nonoverlapping features of T cell activation in cancer
    2023/01/04 by Lestat R. Ali, Ana C. Garrido-Castro, Patrick J. Lenehan +8 · 23 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Advanced Breast Cancer Therapies #Augment #Biology #Blockade #Cancer #Cancer Genomics and Diagnostics #Cancer Immunotherapy and Biomarkers #Cancer research #Cell #Effector #Genetics #Immunology #Internal medicine #Medicine #Melanoma #Oncology #Ovarian cancer #Receptor
57. Senescent cell population with ZEB1 transcription factor as its main regulator promotes osteoarthritis in cartilage and meniscus
    2022/12/23 by Hannah Swahn, Kun Li, Tomás Duffy +11 · 29 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Anatomy #Biology #Cartilage #Cell #Cell biology #Extracellular matrix #Gene #Gene expression #Genetics #Medicine #Meniscus #Muscle Physiology and Disorders #Osteoarthritis #Osteoarthritis Treatment and Mechanisms #Pathology #Population #Single-cell and spatial transcriptomics #Transcription factor
58. Lysosome signaling in cell survival and programmed cell death for cellular homeostasis
    2022/12/11 by Srimanta Patra, Shankargouda Patil, Daniel J. Klionsky +1 · 24 citations
    Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · Medicine · #Apoptosis #Autophagy in Disease and Therapy #Biochemistry #Biology #Calcium signaling and nucleotide metabolism #Cell #Cell biology #Cell survival #Enzyme #Homeostasis #Lysosome #Programmed cell death #Toxoplasma gondii Research Studies
59. The central scaffold protein CEP350 coordinates centriole length, stability, and maturation
    2022/10/31 by Onur Rojhat Karasu, Annett Neuner, Enrico Salvatore Atorino +2 · 7 citations
    Biochemistry, Genetics and Molecular Biology · #Biology #Cell #Cell biology #Cell cycle #Centriole #Centrosome #Genetics #Microtubule #Microtubule and mitosis dynamics #Photosynthetic Processes and Mechanisms #Protist diversity and phylogeny #Scaffold protein #Signal transduction
60. An optimized flow cytometry panel for classifying macrophage polarization
    2022/10/18 by Liyuan Liu, John V. Stokes, Wei Tan +1 · 26 citations
    Immunology and Microbiology · Neuroscience · #Antigen #Biology #Cell #Cell biology #Cell type #Flow cytometry #Genetics #Immune Response and Inflammation #Immune cells in cancer #Immune system #Immunology #In vitro #Inflammation #Macrophage #Macrophage polarization #Neuroinflammation and Neurodegeneration Mechanisms

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