61. Integrated single-cell analysis-based classification of vascular mononuclear phagocytes in mouse and human atherosclerosis
    2022/09/30 by Alma Zernecke, Florian Erhard, Tobias Weinberger +5 · 30 citations
    Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · Medicine · #Atherosclerosis and Cardiovascular Diseases #Biochemistry #Biology #Cell #Cell type #Foam cell #Immune cells in cancer #Immunology #In vitro #Macrophage #Medicine #Pathology #Peripheral blood mononuclear cell #Single-cell and spatial transcriptomics
62. Green synthesis of gold nanoparticles using quercetin biomolecule from mangrove plant, Ceriops tagal: Assessment of antiproliferative properties, cellular uptake and DFT studies
    2022/09/17 by A. Parthiban, V. Sachithanandam, Saran Sarangapany +6 · 7 citations
    Agricultural and Biological Sciences · Chemistry · Materials Science · #Analytical Chemistry (journal) #Biochemistry #Cell #Chemical engineering #Chemistry #Colloidal gold #Fourier transform infrared spectroscopy #HeLa #Materials science #Medicinal Plant Research #Moringa oleifera research and applications #Nanoparticle #Nanoparticles: synthesis and applications #Nanotechnology #Nuclear chemistry #Organic chemistry #Quercetin #Surface plasmon resonance
63. Unified multiscale theory of cellular mechanical adaptations to substrate stiffness
    2022/08/17 by Peng-Cheng Chen, Pengcheng Chen, Xi-Qiao Feng +2 · 5 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · Engineering · Physics and Astronomy · #3D Printing in Biomedical Research #Biological system #Biology #Biophysics #Cell #Cell biology #Cell migration #Cell polarity #Cellular Mechanics and Interactions #Cellular adaptation #Chemistry #Extracellular matrix #Force Microscopy Techniques and Applications #Mechanobiology #Morphogenesis #Physics #Rigidity (electromagnetism) #Stiffness
64. Glucocorticoids enhance chemotherapy-driven stress granule assembly and impair granule dynamics, leading to cell death
    2022/06/17 by Avital Schwed-Gross, Hila Hamiel, Gabriel P. Faber +6 · 10 citations
    Biochemistry, Genetics and Molecular Biology · #Apoptosis #Biochemistry #Biology #Cancer research #Cell #Cell biology #Cell division #Chemotherapy #Cortisone #Cytokinesis #Endocrinology #Endoplasmic Reticulum Stress and Disease #Fungal and yeast genetics research #Genetics #Mitosis #Pharmacology #Programmed cell death #RNA Research and Splicing #Vinblastine #Vinca #Vinorelbine
65. IL‐13 in dermal type‐2 dendritic cell specialization: From function to therapeutic targeting
    2022/06/02 by Olivier Lamiable, Maia Brewerton, Franca Ronchese · 8 citations
    Immunology and Microbiology · Medicine · #Acquired immune system #Antigen #Antigen presentation #Antigen-presenting cell #Biology #Cell #Cell biology #Cell type #Dendritic cell #Dermatology and Skin Diseases #Immune Cell Function and Interaction #Immune system #Immunology #Immunotherapy and Immune Responses #Innate lymphoid cell #T cell
66. Paradoxical roles of caspase-3 in regulating cell survival, proliferation, and tumorigenesis
    2022/05/12 by Ebrahim Eskandari, Connie J. Eaves · 29 citations
    Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · #Apoptosis #Biology #Carcinogenesis #Caspase #Cell #Cell biology #Cell death mechanisms and regulation #Cell growth #DNA Repair Mechanisms #Gene #Genetics #Multicellular organism #Plant-Microbe Interactions and Immunity #Programmed cell death #Yeast
67. E-cadherin to N-cadherin switching in the TGF-β1 mediated retinal pigment epithelial to mesenchymal transition
    2022/04/29 by Jiayi Wei, Liangjing Wu, Shuai Yang +5 · 13 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Biochemistry #Biology #Cadherin #Cancer research #Cancer-related Molecular Pathways #Catenin #Cell #Cell biology #Chemistry #Downregulation and upregulation #Epithelial–mesenchymal transition #Hippo pathway signaling and YAP/TAZ #Proliferative vitreoretinopathy #Retinal #Retinal detachment #Retinal pigment epithelium #Signal transduction #Transforming growth factor #Wnt signaling pathway #Wnt/β-catenin signaling in development and cancer
68. Reprogramming of Cell Death Pathways by Bacterial Effectors as a Widespread Virulence Strategy
    2022/04/25 by Joseph J. Wanford, Abderrahman Hachani, Charlotte Odendall · 16 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Antibiotic Resistance in Bacteria #Autophagy in Disease and Therapy #Biology #Cell #Cell biology #Effector #Gene #Genetics #Microbiology #Reprogramming #Vibrio bacteria research studies #Virulence
69. Ecological drivers of division of labour in Streptomyces
    2022/04/22 by Matthew F. Traxler, Daniel E. Rozen · 1 citation
    Biochemistry, Genetics and Molecular Biology · Medicine · Environmental Science · #Protist diversity and phylogeny #Microbial Natural Products and Biosynthesis #Microbial Community Ecology and Physiology #Multicellular organism #Biology #Division of labour #Streptomyces #Division (mathematics) #Organism #Ecology #Cell division #Bacteria #Genetics #Cell #Economics
70. Acute aerobic exercise‐conditioned serum reduces colon cancer cell proliferation in vitro through interleukin‐6‐induced regulation of DNA damage
    2022/02/25 by Samuel T. Orange, Alastair Jordan, Alastair R. Jordan +8 · 25 citations
    Medicine · #Adipokines, Inflammation, and Metabolic Diseases #Aerobic exercise #Biochemistry #Biology #Cancer #Cancer cell #Cancer survivorship and care #Cell #Cell growth #Colorectal cancer #DNA #DNA damage #Endocrinology #Exercise and Physiological Responses #Immunology #Internal medicine #Medicine #Oncology
71. Rational Design of Nanotherapeutics Based on the Five Features Principle for Potent Elimination of Cancer Stem Cells
    2022/01/25 by Zhijie Zhang, Qingyuan Deng, Chen Xiao +2 · 16 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · Engineering · Materials Science · Medicine · #Biochemistry #Biology #Cancer #Cancer cell #Cancer research #Cancer stem cell #Cell #Cell biology #Chemistry #Drug delivery #Extracellular vesicles in disease #Internal medicine #Internalization #Materials science #Medicine #Metastasis #Nanoparticle-Based Drug Delivery #Nanoplatforms for cancer theranostics #Nanotechnology #Rational design #Stem cell
72. In Vivo Melanoma Cell Morphology Reflects Molecular Signature and Tumor Aggressiveness
    2022/01/07 by Alessandra Marconi, Marika Quadri, Francesca Farnetani +11 · 15 citations
    Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · Medicine · #Cell #Cell type #Confocal #Confocal microscopy #Cutaneous Melanoma Detection and Management #Immunotherapy and Immune Responses #In vivo #Melanoma #Melanoma and MAPK Pathways #Skin cancer #Transcriptome
73. SARS-CoV-2 T Cell Responses Elicited by COVID-19 Vaccines or Infection Are Expected to Remain Robust against Omicron
    2022/01/02 by Syed Faraz Ahmed, Ahmed Abdul Quadeer, Matthew R. McKay · 2 citations
    Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · Medicine · #Antibody #Biology #Cell #Coronavirus disease 2019 (COVID-19) #Disease #Epitope #Genetics #Immune system #Immunology #Immunotherapy and Immune Responses #Infectious disease (medical specialty) #Medicine #SARS-CoV-2 and COVID-19 Research #Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) #T cell #Virology #vaccines and immunoinformatics approaches
74. Cytoskeleton-mediated alterations of nuclear mechanics by extracellular mechanical signals
    2021/12/21 by Xiangjun Peng, Yuxuan Huang, Farid Alisafaei · 5 citations
    Biochemistry, Genetics and Molecular Biology · #Biology #Biophysics #Cell #Cell biology #Cellular Mechanics and Interactions #Cytoskeleton #Extracellular #Genetics #Microtubule and mitosis dynamics #Nuclear Structure and Function
75. Reinvestigation of Classic T Cell Subsets and Identification of Novel Cell Subpopulations by Single-Cell RNA Sequencing
    2021/12/15 by Xuefei Wang, Xiangru Shen, Shan Chen +5 · 26 citations
    Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · #Biology #Cell #Computational biology #Exome sequencing #Gene #Genetics #Identification (biology) #Immune Cell Function and Interaction #Phenotype #RNA #Single cell sequencing #Single-cell and spatial transcriptomics #T-cell and B-cell Immunology
76. B Cell Activation and Plasma Cell Differentiation Are Promoted by IFN-λ in Systemic Lupus Erythematosus
    2021/11/22 by Jennifer L Barnas, Jennifer L. Barnas, Jennifer S. Albrecht +10 · 19 citations
    Chemistry · Immunology and Microbiology · Medicine · #Antibody #Biochemistry #Cell #Chemistry #Immune Cell Function and Interaction #Immunology #Internal medicine #Lupus erythematosus #Medicine #Plasma cell #Systemic Lupus Erythematosus Research #Systemic lupus erythematosus #T-cell and B-cell Immunology
77. Activation of Fibroblasts in Skin Cancer
    2021/09/30 by Lisette Van Hove, Esther Hoste · 10 citations
    Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · Medicine · #Biology #Cancer #Cancer Cells and Metastasis #Cancer cell #Cancer research #Cancer-Associated Fibroblasts #Cell #Cell biology #Cell culture #Cell type #Fibroblast #Gene #Genetics #Hippo pathway signaling and YAP/TAZ #Immune cells in cancer #Melanoma #Phenotype #Skin cancer #Tumor cells #Tumor microenvironment
78. Deciphering mouse uterine receptivity for embryo implantation at single‐cell resolution
    2021/09/23 by Yi Yang, Qiu‐Yang Zhu, Jilong Liu · 1 citation
    Immunology and Microbiology · Medicine · Biochemistry, Genetics and Molecular Biology · #Reproductive System and Pregnancy #Organ and Tissue Transplantation Research #Single-cell and spatial transcriptomics #Biology #Embryo #Uterus #Laser capture microdissection #Blastocyst #Cell biology #Cell type #Cell #Stromal cell #Microarray analysis techniques #Gene expression #Andrology #Gene #Endocrinology #Genetics #Embryogenesis #Cancer research #Medicine
79. KIF12 Variants and Disturbed Hepatocyte Polarity in Children with a Phenotypic Spectrum of Cholestatic Liver Disease
    2021/09/20 by Amelie Stalke, Malte Sgodda, Tobias Cantz +6 · 19 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Antibody #Biology #Cell #Cholestasis #Disease #Drug Transport and Resistance Mechanisms #Gastroenterology #Gene #Genetic and Kidney Cyst Diseases #Genetics #Hepatocyte #Immunofluorescence #Immunology #In vitro #Internal medicine #Liver disease #Liver physiology and pathology #Liver transplantation #Medicine #Pathology #Phenotype #Polarity (international relations) #Progressive familial intrahepatic cholestasis
80. Multiplexed and reproducible high content screening of live and fixed cells using the Dye Drop method
    2021/08/28 by Caitlin E. Mills, Kartik Subramanian, Marc Hafner +9 · 1 citation
    Biochemistry, Genetics and Molecular Biology · Chemistry · Engineering · Medicine · #Advanced Fluorescence Microscopy Techniques #Biochemistry #Bioinformatics #Biology #Biomedical engineering #Cell #Cell Image Analysis Techniques #Chemistry #Computational biology #Computer science #Drop (telecommunication) #Engineering #Flow cytometry #High-content screening #High-throughput screening #Limiting #Materials science #Medicine #Molecular biology #Multiplexing #Nanotechnology #Single-cell and spatial transcriptomics
81. FHL2 anchors mitochondria to actin and adapts mitochondrial dynamics to glucose supply
    2021/08/03 by Himanish Basu, Gulcin Pekkurnaz, Gülçin Pekkurnaz +7 · 25 citations
    Biochemistry, Genetics and Molecular Biology · #ATP Synthase and ATPases Research #Actin #Actin cytoskeleton #Anchoring #Biochemistry #Biology #Cell #Cell biology #Cytoskeleton #Mechanism (biology) #Metabolism and Genetic Disorders #Mitochondrial Function and Pathology #Mitochondrion #Physics
82. SARS-CoV-2 Initiates Programmed Cell Death in Platelets
    2021/07/23 by Milka Koupenova, Heather A. Corkrey, Olga Vitseva +14 · 29 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Apoptosis #Blood cell #COVID-19 Clinical Research Studies #Cell #Extracellular vesicles in disease #Platelet #Platelet Disorders and Treatments #Programmed cell death
83. Getting started for migration: A focus on EMT cellular dynamics and mechanics in developmental models
    2021/07/07 by Meritxell Font-Noguera, Marianne Montemurro, Corinne Benassayag +2 · 1 voice · 7 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · Neuroscience · #Biology #Cancer Cells and Metastasis #Cell #Cell biology #Cell migration #Cellular Mechanics and Interactions #Computational biology #Developmental Biology and Gene Regulation #Dynamics (music) #Embryo #Embryogenesis #Epithelial–mesenchymal transition #Gastrulation #Genetics #Mesenchymal stem cell #Metastasis #Motility #Neuroscience #Physics #Zebrafish
84. Single‐cell analysis of mouse and human prostate reveals novel fibroblasts with specialized distribution and microenvironment interactions
    2021/06/26 by Diya B Joseph, Diya B. Joseph, Gervaise H Henry +18 · 30 citations
    Medicine · #Biology #Bladder and Urothelial Cancer Treatments #Cancer research #Cell #Cell biology #Cell culture #Cell type #Endocrinology #Extracellular matrix #Fibroblast #Hyperplasia #Medicine #Pathology #Prostate #Prostate Cancer Diagnosis and Treatment #Signal transduction #Stromal cell #Urinary Bladder and Prostate Research #Wnt signaling pathway
85. A ciliopathy complex builds distal appendages to initiate ciliogenesis
    2021/06/15 by Dhivya Kumar, Addison Rains, Addison B. Rains +15 · 23 citations
    Biochemistry, Genetics and Molecular Biology · #Anatomy #Appendage #Biology #Cell #Cell biology #Cell cycle #Centriole #Centrosome #Ciliogenesis #Ciliopathies #Ciliopathy #Cilium #Genetic and Kidney Cyst Diseases #Genetics #Hedgehog Signaling Pathway Studies #Microtubule #Microtubule and mitosis dynamics
86. Upregulation of VCAM-1 in lymphatic collectors supports dendritic cell entry and rapid migration to lymph nodes in inflammation
    2021/05/14 by Jorge Arasa, Víctor Collado‐Díaz, Victor Collado-Diaz +18 · 31 citations
    Chemistry · Medicine · #Allergic Rhinitis and Sensitization #Biology #C-C chemokine receptor type 7 #Cell #Cell biology #Cell migration #Chemistry #Chemokine #Dendritic cell #Downregulation and upregulation #Immune system #Immunology #Inflammation #Lymph #Lymphatic Endothelium #Lymphatic System and Diseases #Lymphatic system #Lymphatic vessel #Medicine #Pathology
87. Luminescence lifetime imaging of three-dimensional biological objects
    2021/05/01 by Ruslan I. Dmitriev, Xavier Intes, Margarida Barroso +1 · 26 citations
    Biochemistry, Genetics and Molecular Biology · Chemical Engineering · Medicine · #Advanced Fluorescence Microscopy Techniques #Analytical Chemistry and Sensors #Biochemistry #Biological imaging #Biology #Biophysics #Cell #Context (archaeology) #Fluorescence #Fluorescence-lifetime imaging microscopy #Förster resonance energy transfer #In vivo #Live cell imaging #Luminescence #Materials science #Microscopy #Molecular imaging #Nanotechnology #Optical Imaging and Spectroscopy Techniques #Optics #Optoelectronics
88. Tumor cell nuclei soften during transendothelial migration
    2021/04/05 by Anya B. Roberts, Anya Burkart. Roberts, Jitao Zhang +7 · 28 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Actin #Biology #Biophysics #Cell #Cell biology #Cell migration #Cellular Mechanics and Interactions #Chemistry #Confocal #Confocal microscopy #Cytoskeleton #Extravasation #Materials science #Medicine #Nuclear Structure and Function #Optics #Pathology #Skin and Cellular Biology Research
89. Single-cell profiling of myasthenia gravis identifies a pathogenic T cell signature
    2021/03/28 by Florian Ingelfinger, Sinduya Krishnarajah, Michael H. Kramer +23 · 22 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Antibody #Antifungal resistance and susceptibility #Autoantibody #Autoimmunity #Biology #Cell #Disease #Effector #Genetics #Immune system #Immunology #Medicine #Myasthenia Gravis and Thymoma #Myasthenia gravis #Pathogenesis #Pathology #Single-cell and spatial transcriptomics
90. Yes associated protein 1 promotes resistance to 5-fluorouracil in gastric cancer by regulating GLUT3-dependent glycometabolism reprogramming of tumor-associated macrophages
    2021/03/13 by Zhanke He, Da Chen, Jiani Wu +9 · 25 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · #Biochemistry #Biology #Cancer #Cancer cell #Cancer research #Cancer-related gene regulation #Cell #Cell biology #Chemistry #Endocrinology #GLUT1 #GLUT3 #Gene #Genetics #Glucose transporter #Hippo pathway signaling and YAP/TAZ #In vitro #Macrophage #Macrophage polarization #Reprogramming #Transcription factor #Ubiquitin and proteasome pathways #YAP1

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