- Nociceptor sodium channels shape subthreshold phase, upstroke, and shoulder of action potentials
2024/12/19 by Phil Alexander Köster, Enrico Leipold, Jenny Tigerholm +4 · 8 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · Neuroscience · #Biochemistry #Biology #Biophysics #Chemistry #Current clamp #Depolarization #Electrophysiology #Gating #Ion channel regulation and function #Membrane potential #Neuroscience #Neuroscience and Neuropharmacology Research #Nociception #Nociceptor #Pain Mechanisms and Treatments #Patch clamp #Physics #Receptor #Sodium #Sodium channel #Subthreshold conduction
- Gating and modulation of an inward-rectifier potassium channel
2022/12/16 by Vishwanath Jogini, Morten Ø. Jensen, David E. Shaw · 9 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · Neuroscience · #Binding site #Biochemistry #Biology #Biophysics #Cardiac electrophysiology and arrhythmias #Chemistry #Crystallography #Gating #Inward-rectifier potassium ion channel #Ion channel #Ion channel regulation and function #KcsA potassium channel #Ligand-gated ion channel #Neuroscience and Neuropharmacology Research #Potassium channel #Receptor #Spermine
- Novel CACNA1A Variant p.Cys256Phe Disrupts Disulfide Bonds and Causes Spinocerebellar Ataxia
2021/10/14 by Yuliia V. Nikonishyna, Nadine J. Ortner, Teresa Kaserer +7 · 1 citation
Neuroscience · Medicine · Biochemistry, Genetics and Molecular Biology · Chemistry · #Genetic Neurodegenerative Diseases #Amyotrophic Lateral Sclerosis Research #Nuclear Structure and Function #Missense mutation #Spinocerebellar ataxia #Mutant #Mutation #Ataxia #Gating #Mutant protein #Protein subunit #Trinucleotide repeat expansion #Loss function #Genetics #Wild type #Biology #Molecular biology #Chemistry #Phenotype #Biophysics #Allele #Gene #Neuroscience
- Simplified Gating in Long Short-term Memory (LSTM) Recurrent Neural Networks
2017/01/12 by Yuzhen Lu, Lu, Yuzhen, Fathi M. Salem +1 · 1 voice · 1 citation
Computer Science · Mathematics · Neuroscience · #Artificial intelligence #Artificial neural network #Computer science #Dependency (UML) #Gating #Human Pose and Action Recognition #Machine learning #Multimodal Machine Learning Applications #Music and Audio Processing #Neuroscience #Pattern recognition (psychology) #Recurrent neural network #Sequence (biology) #Speech recognition #cs.NE #stat.ML
- Structural basis for dynamic regulation of the human 26S proteasome
2016/10/21 by Shuobing Chen, Jiayi Wu, Ying Lu +7 · 5 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #AAA proteins #ATP hydrolysis #ATPase #Biochemistry #Biology #Biophysics #Cell biology #Chemistry #Cryo-electron microscopy #Enzyme #Gating #Glycosylation and Glycoproteins Research #Peptidase Inhibition and Analysis #Proteasome #Protein degradation #Protein structure #Proteolysis #Substrate (aquarium) #Ubiquitin #Ubiquitin and proteasome pathways
- Conformational heterogeneity in closed and open states of the KcsA potassium channel in lipid bicelles
2016/07/18 by Dorothy M. Kim, Igor Dikiy, Vikrant Upadhyay +3 · 10 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Neuroscience · #Biochemistry #Biology #Biophysics #Chemistry #Conformational change #Crystallography #Gating #Ion channel #Ion channel regulation and function #KcsA potassium channel #Lipid Membrane Structure and Behavior #Neuroscience and Neuropharmacology Research #Potassium channel
- The hitchhiker’s guide to the voltage-gated sodium channel galaxy
2015/12/28 by Christopher A. Ahern, Jian Payandeh, Frank Bosmans +1 · 34 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Neuroscience · #Biochemistry #Biology #Biophysics #Cell biology #Chemistry #Gating #Ion channel #Ion channel regulation and function #KcsA potassium channel #Neuroscience and Neuropharmacology Research #Nicotinic Acetylcholine Receptors Study #Potassium channel #Receptor #Sodium #Sodium channel #Voltage-gated ion channel
- Sensory Processing Dysfunction in the Personal Experience and Neuronal Machinery of Schizophrenia
2014/12/17 by Daniel C. Javitt, Robert Freedman · 29 citations
Engineering · Neuroscience · Psychology · #Analog and Mixed-Signal Circuit Design #Cognition #Context (archaeology) #Electroencephalography #Gating #Mismatch negativity #Neural dynamics and brain function #Neuroscience #Neuroscience and Music Perception #Perception #Prepulse inhibition #Psychiatry #Psychology #Psychosis #Schizophrenia (object-oriented programming) #Sensory gating #Sensory processing #Sensory system
- Intracellular Magnesium-Dependent Modulation of Gap Junction Channels Formed by Neuronal Connexin36
2013/03/13 by Nicolás Palacios‐Prado, Gregory Hoge, Alina Marandykina +8 · 1 citation
Biochemistry, Genetics and Molecular Biology · Neuroscience · Chemistry · #Connexins and lens biology #Ion channel regulation and function #Neuroscience and Neuropharmacology Research #Gap junction #Gating #Biophysics #Intracellular #Conductance #Chemistry #Connexin #Magnesium #Coupling (piping) #Neuroscience #Biology #Biochemistry #Materials science #Physics
- Sine gating detector with simple filtering for low-noise infra-red single photon detection at room temperature
2012/05/14 by Nino Walenta, Tommaso Lunghi, Olivier Guinnard +3 · 3 citations
Computer Science · Engineering · Physics and Astronomy · #Advanced Optical Sensing Technologies #Advanced Photonic Communication Systems #Detector #Gating #Jitter #Noise (video) #Photodetector #Photon #Quantum Information and Cryptography #Quantum key distribution #Sine wave #physics.ins-det #quant-ph
- Acidosis Differentially Modulates Inactivation in NaV1.2, NaV1.4, and NaV1.5 Channels
2012/01/01 by Yury Y. Vilin, Colin H. Peters, Peter C. Ruben · 5 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · Neuroscience · #Acidosis #Biochemistry #Biology #Biophysics #Cardiac electrophysiology and arrhythmias #Chemistry #Depolarization #Endocrinology #Extracellular #Gating #Ion channel regulation and function #Membrane potential #NAV1 #Nav1.5 #Neuroscience and Neural Engineering #Sodium #Sodium channel
- Bi-stability, hysteresis, and memory of voltage-gated lysenin channels
2011/09/15 by Daniel Fologea, Eric Krueger, Yuriy I. Mazur +5 · 12 citations
Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · Chemistry · Neuroscience · #Bilayer #Biochemistry #Biology #Biophysics #Chemical physics #Chemistry #Conductance #Gating #Hysteresis #Ion channel #Lipid Membrane Structure and Behavior #Lipid bilayer #Materials science #Membrane #Nanotechnology #Photoreceptor and optogenetics research #Physics #Plant and Biological Electrophysiology Studies #Voltage
- State-dependent electrostatic interactions of S4 arginines with E1 in S2 during Kv7.1 activation
2010/05/17 by Dick Wu, Kelli Delaloye, Mark A. Zaydman +3 · 26 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · Neuroscience · #Biochemistry #Biology #Biophysics #Cardiac electrophysiology and arrhythmias #Chemistry #Electrostatics #Gating #Gene #Ion channel regulation and function #Membrane #Membrane potential #Mutation #Neuroscience and Neural Engineering #Transmembrane domain
- Different pathways for activation and deactivation in CaV1.2: a minimal gating model
2009/08/17 by Stanislav Beyl, Philipp Kügler, Michaela Kudrnac +3 · 9 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Engineering · Medicine · #Advanced Memory and Neural Computing #Biochemistry #Biology #Biophysics #Cardiac electrophysiology and arrhythmias #Cav1.2 #Chemistry #Electrical engineering #Gating #Ion channel regulation and function #Kinetics #Membrane potential #Physics #Reaction rate constant #Time constant #Voltage #Voltage-dependent calcium channel
- Channel-like slippage modes in the human anion/proton exchanger ClC-4
2009/04/13 by Alexi K. Alekov, Christoph Fahlke · 19 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · Neuroscience · #Biochemistry #Biophysics #Cardiac electrophysiology and arrhythmias #Chemical physics #Chemistry #Gating #Ion #Ion channel #Ion channel regulation and function #Ion transporter #Materials science #Neuroscience and Neuropharmacology Research #Physics #Proton #Slippage
- Arachidonic acid inhibition of L-type calcium (CaV1.3b) channels varies with accessory CaVβ subunits
2009/03/30 by Mandy L. Roberts-Crowley, Ann R. Rittenhouse · 19 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · Neuroscience · #Arachidonic acid #Biochemistry #Biology #Biophysics #Calcium #Cardiac electrophysiology and arrhythmias #Cav1.2 #Chemistry #Electrophysiology #Enzyme #Gating #Ion channel regulation and function #L-type calcium channel #Neuroscience #Neuroscience and Neuropharmacology Research #Patch clamp #Protein subunit #Receptor #Voltage-dependent calcium channel
- Side-chain recognition and gating in the ribosome exit tunnel
2008/10/22 by Paula Petrone, Christopher D. Snow, Del Lucent +1 · 2 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · #RNA and protein synthesis mechanisms #RNA modifications and cancer #RNA Research and Splicing #Ribosome #Ribosomal protein #Ribosomal RNA #Amino acid #Biophysics #Gating #Translation (biology) #RNA #Biology #Biochemistry #Physics #Chemistry #Messenger RNA #Gene
- Molecular Basis of Cardiac Action Potential Repolarization
2008/03/01 by Yoram Rudy · 1 citation
Medicine · Biochemistry, Genetics and Molecular Biology · Chemistry · #Cardiac electrophysiology and arrhythmias #Ion channel regulation and function #Electrochemical Analysis and Applications #Repolarization #Cardiac action potential #Chemistry #Ion channel #Gating #Pharmacology #Ventricular action potential #Biophysics #Electrophysiology #Internal medicine #Biology #Medicine #Biochemistry #Receptor
- Whither withered Golgi?
2007/02/16 by Lawrence Kruger, Thomas S. Otis · 1 citation
Neuroscience · Psychology · #Biology #Cognitive science #Gating #Golgi apparatus #Neurology and Historical Studies #Neuron #Neuroscience #Neuroscience and Neuropharmacology Research #Philosophy #Photoreceptor and optogenetics research #Psychology #Synapse
- Sodium Currents Activate without a Hodgkin and Huxley-Type Delay in Central Mammalian Neurons
2006/01/11 by Gytis Baranauskas, Marco Martina · 1 citation
Neuroscience · Biochemistry, Genetics and Molecular Biology · Chemistry · Psychology · #Neuroscience and Neural Engineering #Neural dynamics and brain function #Ion channel regulation and function #Hodgkin–Huxley model #Sodium channel #Gating #Current (fluid) #Neuroscience #Physics #Chemistry #Sodium #Psychology
- Coupling Interactions between Voltage Sensors of the Sodium Channel as Revealed by Site-specific Measurements
2004/02/23 by Baron Chanda, Osei Kwame Asamoah, Francisco Bezanilla · 28 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Biological system #Biology #Biophysics #Cardiac electrophysiology and arrhythmias #Chemical physics #Chemistry #Coupling (piping) #Electrochemical Analysis and Applications #Gating #Ion channel regulation and function #Materials science #Molecular physics #Physics #Sodium #Sodium channel #Voltage
- Axonal excitability revisited
2004/02/12 by John R. Clay · 1 citation
Biochemistry, Genetics and Molecular Biology · Chemistry · Neuroscience · #Axolemma #Axon #Biochemistry #Biology #Biophysics #Central nervous system #Chemistry #Extracellular #Gating #Hodgkin–Huxley model #Ion channel #Lipid Membrane Structure and Behavior #Membrane potential #Neural dynamics and brain function #Neuroscience #Neuroscience and Neural Engineering #Physics #Receptor #Squid #Squid giant axon
- Induced Oscillations in the Alpha Band: Functional Meaning
2003/12/01 by G. Pfurtscheller · 27 citations
Neuroscience · Psychology · #Alpha (finance) #Anatomy #Biology #Computer science #Developmental psychology #EEG and Brain-Computer Interfaces #Electroencephalography #Gating #Neural dynamics and brain function #Neuroscience #Neuroscience and Neural Engineering #Physics #Psychology #Scalp #Synchronization (alternating current) #Telecommunications
- Involvement of Helices at the Dimer Interface in ClC-1 Common Gating
2003/02/01 by Michael D. Duffield, Michael Duffield, Grigori Y. Rychkov +5 · 19 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Biochemistry #Biology #Biophysics #Cardiac electrophysiology and arrhythmias #Chemistry #Chloride channel #Crystallography #Dimer #Gating #Gene #Genetics #Helix (gastropod) #Ion channel regulation and function #Mutagenesis #Mutant #Mutation #Myotonia #Nicotinic Acetylcholine Receptors Study #Sodium #Sodium channel
- Tracking Voltage-dependent Conformational Changes in Skeletal Muscle Sodium Channel during Activation
2002/10/29 by Baron Chanda, Francisco Bezanilla · 35 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · Neuroscience · #Analytical Chemistry (journal) #Biology #Biophysics #Cardiac electrophysiology and arrhythmias #Chemistry #Chromatography #Fluorescence #Gating #Ion channel regulation and function #Kinetics #Neuroscience and Neural Engineering #Physics #Sodium #Sodium channel
- Gating Kinetics of the α1i T-Type Calcium Channel
2001/10/15 by Charles J. Frazier, José Ramón Serrano, Jose R. Serrano +6 · 9 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · Neuroscience · #Biochemistry #Biology #Biophysics #Calcium #Cardiac electrophysiology and arrhythmias #Chemistry #Electrophysiology #Gating #HEK 293 cells #Ion channel regulation and function #Kinetics #Neuroscience #Neuroscience and Neural Engineering #Patch clamp #Physics #Potassium channel #Time constant #Voltage-dependent calcium channel
- The Voltage Sensor in Voltage-Dependent Ion Channels
2000/01/04 by Francisco Bezanilla · 1 citation
Biochemistry, Genetics and Molecular Biology · Chemistry · Neuroscience · #Ion channel regulation and function #Electrochemical Analysis and Applications #Photoreceptor and optogenetics research #Gating #Chemistry #Voltage #Membrane potential #Electrophysiology #Ion channel #Voltage-gated ion channel #Biophysics #Physics #Biochemistry
- Spectroscopic mapping of voltage sensor movement in the Shaker potassium channel
1999/12/01 by K. S. Glauner, L. M. Mannuzzu, Lidia M. Mannuzzu +4 · 3 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · Neuroscience · #Acoustics #Biochemistry #Biology #Biophysics #Cardiac electrophysiology and arrhythmias #Chemistry #Coupling (piping) #Gating #Ion channel #Ion channel regulation and function #Materials science #Nanotechnology #Neuroscience and Neural Engineering #Physics #Potassium channel #Shaker #Voltage #Voltage-gated ion channel
- Structure and function of cardiac potassium channels
1999/05/01 by Dirk J. Snyders · 1 citation
Medicine · Biochemistry, Genetics and Molecular Biology · Neuroscience · Chemistry · #Cardiac electrophysiology and arrhythmias #Ion channel regulation and function #Neuroscience and Neuropharmacology Research #Protein subunit #Biophysics #Membrane potential #Potassium channel #Gating #Inward-rectifier potassium ion channel #Depolarization #Ion channel #Cardiac action potential #Transmembrane protein #Ligand-gated ion channel #Transmembrane domain #Chemistry #KcsA potassium channel #Electrophysiology #Voltage-gated ion channel #Biology #Neuroscience #Biochemistry #Repolarization #Membrane #Receptor
- Electrocoupling of Ion Transporters in Plants: Interaction with Internal Ion Concentrations
1998/11/01 by D. Gradmann, Johannes Hoffstadt, J. Hoffstadt · 1 citation
Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · Chemistry · #Analytical Chemistry (journal) #Biochemistry #Biology #Biophysics #Chemistry #Chromatography #Conductance #Gating #Ion #Ion channel regulation and function #Ion transporter #Membrane potential #Physics #Plant Stress Responses and Tolerance #Plant and Biological Electrophysiology Studies #Steady state (chemistry) #Symporter #Time constant #Transporter
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